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• Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, phenformin, and AICAR

  Sakamoto, K., Goransson, O., Hardie, D. G. & Alessi, D. R., Aug 2004, In: AJP - Endocrinology and Metabolism (Endocrinology and Metabolism. 287, 2, p. E310-E317

  Research output: Contribution to journal › Article › peer-review

  • acadesine 100%
  • Phenformin 95%
  • AMP-activated protein kinase kinase 90%
  • Muscle Contraction 61%
  • Skeletal Muscle 47%
  254 Citations (Scopus)

• Activity of any class IA PI3K isoform can sustain cell proliferation and survival

  Foukas, L. C., Berenjeno, I. M., Gray, A., Khwaja, A. & Vanhaesebroeck, B., 22 Jun 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 25, p. 11381-11386 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Phosphatidylinositol 3-Kinases 100%
  • Protein Isoforms 81%
  • Cell Survival 76%
  • Cell Proliferation 66%
  • MAP Kinase Signaling System 9%
  120 Citations (Scopus)

• Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity

  Pao, K-C., Wood, N. T., Knebel, A., Rafie, K., Stanley, M., Mabbitt, P. D., Sundaramoorthy, R., Hofmann, K., van Aalten, D. M. F. & Virdee, S., 11 Apr 2018, In: Nature. 556, 7701, p. 381-385 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Esterification 100%
  • Ubiquitin-Protein Ligases 86%
  • Ubiquitin 76%
  • Ubiquitination 30%
  • Genes 30%
  67 Citations (Scopus)

  469 Downloads (Pure)

• Activities related to the occurrence of traumatic dental injuries in 15- to 18-year-olds

  Huang, B., Marcenes, W., Croucher, R. & Hector, M., 1 Feb 2009, In: Dental Traumatology. 25, 1, p. 64-68 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Tooth Injuries 100%
  • Economic Status 23%
  • Traffic Accidents 16%
  • Leisure Activities 15%
  • Taiwan 13%
  29 Citations (Scopus)

• Activism, separation of powers and development

  Mishra, A. & Anant, T. C. A., Dec 2006, In: Journal of Development Economics. 81, 2

  Research output: Contribution to journal › Article › peer-review

  • Separation of Powers 100%
  • separation of powers 72%
  • Activism 55%
  • organization 42%
  • corruption 26%
  2 Citations (Scopus)

• Active β-Amyloid Immunization Restores Spatial Learning in PDAPP Mice Displaying Very Low Levels of β-Amyloid

  Chen, G., Chen, K. S., Kobayashi, D., Barbour, R., Motter, R., Games, D., Martin, S. J. & Morris, R. G. M., 7 Mar 2007, In: Journal of Neuroscience. 27, 10, p. 2654-2662 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Spatial Learning 100%
  • Amyloid 78%
  • Vaccination 66%
  • Serial Learning 29%
  • Learning 20%
  41 Citations (Scopus)

• Active water transport in unicellular algae: where, why, and how

  Raven, J. A. & Doblin, M. A., 22 Dec 2014, In: Journal of Experimental Botany. 65, 22, p. 6279-6292 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Active Biological Transport 100%
  • algae 65%
  • Xylem 56%
  • Water 54%
  • water 33%
  26 Citations (Scopus)

• Active Vertex Model for Cell-Resolution Description of Epithelial Tissue Mechanics

  Barton, D. L., Henkes, S., Weijer, C. J. & Sknepnek, R., 30 Jun 2017, In: PLoS Computational Biology. 13, 6, 34 p., e1005569.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Vertex Model 100%
  • mechanics 81%
  • Mechanics 77%
  • Tissue 63%
  • epithelium 59%
  78 Citations (Scopus)

  210 Downloads (Pure)

• Active transport of the Ubiquitin Ligase MID1 along the microtubules Is regulated by Protein Phosphatase 2A

  Aranda-Orgilles, B., Aigner, J., Kunath, M., Lurz, R., Schneider, R. & Schweiger, S., 24 Oct 2008, In: PLoS ONE. 3, 10, p. - 8 p., e3507.

  Research output: Contribution to journal › Article › peer-review

  • Protein Phosphatase 2 100%
  • Active Biological Transport 94%
  • Ligases 84%
  • Ubiquitin 77%
  • Microtubules 75%
  32 Citations (Scopus)

• Active swarms on a sphere

  Sknepnek, R. & Henkes, S., 17 Feb 2015, In: Physical Review E: Statistical, Nonlinear, and Soft Matter Physics. 91, 2, 5 p., 022306.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Swarm 100%
  • Collective Motion 75%
  • Motion 50%
  • Hairy ball theorem 47%
  • Curvature 36%
  40 Citations (Scopus)

  249 Downloads (Pure)

• Active stabilisation and timing jitter characterisation of sub-500fs pulse passively modelocked VECSEL

  Quarterman, A. H., Wilcox, K. G., Elsmere, S. P., Mihoubi, Z. & Tropper, A. C., 16 Sep 2008, In: Electronics Letters. 44, 19, p. 1135-1137 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Timing jitter 100%
  • Surface emitting lasers 96%
  • Laser pulses 88%
  • Frequency synthesizers 86%
  • Stabilization 57%
  28 Citations (Scopus)

• Active-site topologies of human CYP2D6 and its aspartate-301 → glutamate, asparagine, and glycine mutants

  Mackman, R., Tschirret-Guth, R. A., Smith, G., Hayhurst, G. P., Ellis, S. W., Lennard, M. S., Tucker, G. T., Wolf, C. R. & Ortiz de Montellano, P. R., 1996, In: Archives of Biochemistry and Biophysics. 331, 1, p. 134-140 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Cytochrome P-450 CYP2D6 100%
  • Asparagine 99%
  • Aryl Group 89%
  • Cytochrome P450 85%
  • Aspartic Acid 83%
  44 Citations (Scopus)

• Active site residues in m-calpain: identification by site-directed mutagenesis

  Arthur, J. S. C., Gauthier, S. & Elce, J. S., 24 Jul 1995, In: FEBS Letters. 368, 3, p. 397-400 4 p.

  Research output: Contribution to journal › Article › peer-review

  • m-calpain 100%
  • Calpain 76%
  • Site-Directed Mutagenesis 66%
  • Catalytic Domain 55%
  • Cysteine 53%
  50 Citations (Scopus)

• Active site models of human cytochrome P450s based on NMR relaxation measurements

  Modi, S., Paine, M. J., Oliver, C. F., Smith, G., Sutcliffe, M. J., Gilham, D. E., Shaw, A. N. J., Lian, L. Y., Primrose, W. U., Wolf, C. R. & Roberts, G. C. K., 1997, In: FASEB Journal. 11, 9, p. A771-A771 1 p.

  Research output: Contribution to journal › Meeting abstract › peer-review

  • Cytochrome P-450 CYP2D6 100%
  • Cytochromes 90%
  • Cytochrome P450 85%
  • Protons 81%
  • Catalytic Domain 71%

• Active self-management of chronic pain in the community

  Smith, B. H. & Elliott, A. M., Feb 2005, In: Pain. 113, 3, p. 249-50 2 p.

  Research output: Contribution to journal › Editorial › peer-review
  12 Citations (Scopus)

• Active restoration accelerates the carbon recovery of human modified-tropical forests

  Philipson, C., Cutler, M., Brodrick, P. G., Asner, G. P., Boyd, D. S., Costa, P. M., Fiddes, J., Foody, G. M., van der Heijden, G. M. F., Ledo, A., Lincoln, P. R., Margrove, J. A., Martin, R. E., Milne, S., Pinard, M. A., Reynolds, G., Snoep, M., Tangki, H., Wai, Y. S., Wheeler, C. E. & 1 others, Burslem, D. F. R. P., 14 Aug 2020, In: Science. 369, 6505, p. 838-841 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Forests 100%
  • Carbon 82%
  • Biodiversity 19%
  • Costs and Cost Analysis 17%
  • Paris 16%
  9 Citations (Scopus)

  181 Downloads (Pure)

• Active repression of antiapoptotic gene expression by RelA(p65) NF-kB

  Campbell, K. J., Rocha, S. & Perkins, N. D., Mar 2004, In: Molecular Cell. 13, 6, p. 853-865 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Daunorubicin 100%
  • NF-kappa B 83%
  • Gene Expression 47%
  • Histone Deacetylases 30%
  • Ultraviolet Rays 26%
  342 Citations (Scopus)

• Active queue management algorithms in DiffServ networks

  Liu, W., Cheng, W. Q., He, J. H., Le, C. H., Chou, C. T. & Yang, Z. K., 1 Jun 2005, In: Ruan Jian Xue Bao/Journal of Software. 16, 6, p. 1120-1130 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Throughput 100%
  • Adaptive algorithms 72%
  • Quality of service 56%
  1 Citation (Scopus)

• Active MRI tracking for robotic assisted FUS

  Xiao, X., Huang, Z. & Melzer, A., 1 Mar 2017, Proceedings from the 13th International Symposium on Therapeutic Ultrasound. AIP Publishing, Vol. 1816. 080003

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  Open Access

  File

  • robotics 100%
  • transducers 27%
  • Czech Republic 25%
  • necrosis 23%
  • beam steering 20%
  91 Downloads (Pure)

• Active momentum trading versus passive '1/N naive diversification'

  Banerjee, A. N. & Hung, C-H. D., May 2013, In: Quantitative Finance. 13, 5, p. 655-663 9 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Active microbial ecosystem in glacier basal ice fuelled by iron and silicate comminution‐derived hydrogen

  Toubes-Rodrigo, M., Potgieter-Vermaak, S., Sen, R., Oddsdóttir, E. S., Elliott, D. & Cook, S., Aug 2021, In: MicrobiologyOpen. 10, 4, 13 p., e1200.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Ice Cover 100%
  • Silicates 94%
  • Ice 77%
  • Hydrogen 74%
  • Ecosystem 70%

• Active membranes: 3D printing of elastic fibre patterns on pre-stretched textiles

  Agkathidis, A., Berdos, Y. & Brown, A., 1 Mar 2019, In: International Journal of Architectural Computing. 17, 1, p. 74-87 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • 3D printers 100%
  • Textiles 99%
  • Membranes 85%
  • Fibers 69%
  • Laminating 35%
  4 Citations (Scopus)

  49 Downloads (Pure)

• Active-learning methods to improve student performance and scientific interest in a large introductory oceanography course

  Yuretich, R. F., Khan, S., Leckie, R. M. & Clement, J. J., Mar 2001, In: Journal of Geoscience Education. 49, 2, p. 111-119 9 p.

  Research output: Contribution to journal › Article › peer-review

  • oceanography 100%
  • learning method 87%
  • student 74%
  • learning 72%
  • performance 41%
  54 Citations (Scopus)

• Active learning for young people... youth participation, well-being and civic renewal

  Barber, T., 2009.

  Research output: Contribution to conference › Paper

• Active Learning for Patch-Based Digital Pathology using Convolutional Neural Networks to Reduce Annotation Costs

  Carse, J. & McKenna, S., 2019, Digital Pathology: 15th European Congress, ECDP 2019, Warwick, UK, April 10–13, 2019, Proceedings. Reyes-Aldasoro, C. C., Janowczyk, A., Veta, M., Bankhead, P. & Sirinukunwattana, K. (eds.). Switzerland: Springer , p. 20-27 8 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 11435 LNCS).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  Open Access

  File

  • Active Learning 100%
  • Annotation 87%
  • Problem-Based Learning 72%
  • Pathology 72%
  • Patch 67%
  2 Citations (Scopus)

  93 Downloads (Pure)

• Active defence responses associated with non-host resistance of Arabidopsis thaliana to the oomycete pathogen Phytophthora infestans

  Huitema, E., Vleeshouwers, V. G. A. A., Francis, D. M. & Kamoun, S., Nov 2003, In: Molecular Plant Pathology. 4, 6, p. 487-500 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Phytophthora infestans 100%
  • Oomycetes 88%
  • Arabidopsis 67%
  • defense 48%
  • infection 48%
  84 Citations (Scopus)

• Activators of the Epstein-Barr virus lytic program concomitantly induce apoptosis, but lytic gene expression protects from cell death

  Inman, G. J., Binné, U. K., Parker, G. A., Farrell, P. J. & Allday, M. J., 2001, In: Journal of Virology. 75, 5, p. 2400-2410 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Human gammaherpesvirus 4 100%
  • Human Herpesvirus 4 74%
  • cell death 69%
  • apoptosis 68%
  • Cell Death 56%
  55 Citations (Scopus)

• Activators of protein kinase C down-regulate and phosphorylate the T3/T-cell antigen receptor complex of human T lymphocytes

  Cantrell, D. A., Davies, A. A. & Crumpton, M. J., 1 Dec 1985, In: Proceedings of the National Academy of Sciences of the United States of America. 82, 23, p. 8158-8162 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • T-Cell Antigen Receptor 100%
  • Protein Kinase C 92%
  • Down-Regulation 68%
  • Phosphorylation 67%
  • T-Lymphocytes 60%
  209 Citations (Scopus)

• Activation status of the Pregnane X Receptor influences Vemurafenib availability in humanized mouse models

  MacLeod, A. K., McLaughlin, L. A., Henderson, C. J. & Wolf, C. R., 1 Nov 2015, In: Cancer Research. 75, 21, p. 4573-4581 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Vemurafenib 100%
  • Pregnane X Receptor 98%
  • Cytochrome P-450 CYP3A 48%
  • Elacridar 14%
  • constitutive androstane receptor 12%
  13 Citations (Scopus)

• Activation of μ-opioid receptors by MT-45 (1-cyclohexyl-4-(1,2-diphenylethyl)piperazine) and its fluorinated derivatives

  Baptista-Hon, D. T., Smith, M., Singleton, S., Antonides, L. H., Daeid, N. N., McKenzie, C. & Hales, T. G., 9 Jul 2020, In: British Journal of Pharmacology. 177, 15, p. 3436-3448 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • (+,-)-1-cyclohexyl-4-(1,2-diphenylethyl)piperazine 100%
  • Opioid Receptors 53%
  • N-Methyl-D-Aspartate Receptors 47%
  • Ala(2)-MePhe(4)-Gly(5)-enkephalin 46%
  • Artificial Receptors 24%
  3 Citations (Scopus)

  47 Downloads (Pure)

• Activation of wnt5a in epidermis triggers massive hypersensitivity to double-stranded RNA

  Reilly, L., Romanowska, M. & Foerster, J., Sep 2010, In: Journal of Investigative Dermatology. 130, S2, p. S84-S84 1 p., 500 [Oral 041].

  Research output: Contribution to journal › Book/Film/Article review › peer-review

• Activation of transcription factor Nrf2 to counteract mitochondrial dysfunction in Parkinson’s disease

  Bento-Pereira, C. & Dinkova-Kostova, A., 18 Jul 2020, (E-pub ahead of print) In: Medicinal Research Reviews. 41, 2, p. 785-802 18 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Oxidative Stress 100%
  • Disorder 86%
  • Parkinson Disease 84%
  • Transcription Factors 75%
  • NF-E2 Transcription Factor 32%
  5 Citations (Scopus)

  35 Downloads (Pure)

• Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD

  Baas, A. F., Boudeau, J., Sapkota, G. P., Smit, L., Medema, R., Morrice, N. A., Alessi, D. R. & Clevers, H. C., 2003, In: EMBO Journal. 22, 12, p. 3062-3072 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Subcellular Localization 100%
  • Silencing RNA 94%
  • Threonine 81%
  • Serine 68%
  • Mutation 61%
  277 Citations (Scopus)

• Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1

  Richardson, C., Rafiqi, F. H., Karlsson, H. K. R., Moleleki, N., Vandewalle, A., Campbell, D. G., Morrice, N. A. & Alessi, D. R., 1 Mar 2008, In: Journal of Cell Science. 121, 5, p. 675-684 10 p.

  Research output: Contribution to journal › Article › peer-review

  • thiazide receptor 100%
  • Member 3 Solute Carrier Family 12 97%
  • Phosphotransferases 44%
  • Phosphorylation 20%
  • Chlorides 12%
  254 Citations (Scopus)

• Activation of the renal Na+:Cl- cotransporter by angiotensin II is a WNK4-dependent process

  Castaneda-Bueno, M., Graciela Cervantes-Perez, L., Vazquez, N., Uribe, N., Kantesaria, S., Morla, L., Bobadilla, N. A., Doucet, A., Alessi, D. R. & Gamba, G., 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 20, p. 7929-7934 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Member 3 Solute Carrier Family 12 100%
  • Lysine 58%
  • Angiotensin II 57%
  • Phosphotransferases 46%
  • Kidney 32%
  169 Citations (Scopus)

• Activation of the Ras mitogen-activated protein kinase ribosomal protein kinase pathway is not required for the repression of phosphoenolpyruvate carboxykinase gene transcription by insulin

  Sutherland, C., Waltner-Law, M., Gnudi, L., Kahn, B. B. & Granner, D. K., 1998, In: Journal of Biological Chemistry. 273, 6, p. 3198-3204 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Phosphoenolpyruvate 100%
  • Ribosomal Proteins 95%
  • Insulin Derivative 77%
  • Mitogen-Activated Protein Kinases 75%
  • Protein Kinases 70%
  48 Citations (Scopus)

• Activation of the protease from human adenovirus type 2 is accompanied by a conformational change that is dependent on cysteine-104

  Jones, S. J., Iqbal, M., Grierson, A. W. & Kemp, G., Aug 1996, In: Journal of General Virology. 77, 8, p. 1821-1824

  Research output: Contribution to journal › Article › peer-review

  • Human Adenoviruses 100%
  • Cysteine 71%
  • Peptide Hydrolases 63%
  • Fluorescence 36%
  • Catalysis 36%
  9 Citations (Scopus)

• Activation of the NRF2 Signaling Pathway by Copper-Mediated Redox Cycling of Para- and Ortho-Hydroquinones

  Wang, X. J., Hayes, J. D., Higgins, L. G., Wolf, C. R. & Dinkova-Kostova, A. T., 29 Jan 2010, In: Chemistry & Biology. 17, 1, p. 75-85 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Hydroquinones 100%
  • 2-tert-butyl-4-quinone 96%
  • Antioxidant Response Elements 85%
  • hydroquinone 83%
  • Copper 59%
  80 Citations (Scopus)

• Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); Comparison of its substrate specificity with that of other SAP kinases

  Goedert, M., Cuenda, A., Craxton, M., Jakes, R. & Cohen, P., 16 Jun 1997, In: EMBO Journal. 16, 12, p. 3563-3571 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mitogen-Activated Protein Kinase 13 100%
  • Substrate Specificity 62%
  • Heat-Shock Proteins 58%
  • Protein Kinases 51%
  • Phosphotransferases 43%
  348 Citations (Scopus)

• Activation of the novel MAP kinase homologue SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6)

  Cuenda, A., Goedert, M., Craxton, M., Jakes, R. & Cohen, P., 1 Nov 1997, In: Biochemical Society Transactions. 25, 4

  Research output: Contribution to journal › Meeting abstract › peer-review
  8 Citations (Scopus)

• Activation of the neutrophil NADPH oxidase is inhibited by SB 203580, a specific inhibitor of SAPK2/p38

  Lal, A. S., Clifton, A. D., Rouse, J., Segal, A. W. & Cohen, P., 7 Jun 1999, In: Biochemical and Biophysical Research Communications. 259, 2, p. 465-470 6 p.

  Research output: Contribution to journal › Article › peer-review

  • SB 203580 100%
  • Mitogen-Activated Protein Kinase 11 92%
  • Neutrophil Activation 64%
  • NADPH Oxidases 58%
  • Phorbol 46%
  59 Citations (Scopus)

• Activation of the MAP kinase pathway requires p21ras and p74raf-1

  Marshall, C. J., Ashworth, A., Howe, L. R., Leevers, S. J., Paterson, H. F., Thorneycroft, S. G., Gomez, N., Nakielny, S., Traverse, S. & Cohen, P., 1 Jan 1993, In: International Journal of Cancer. 53, 1, p. 171-172 2 p.

  Research output: Contribution to journal › Article › peer-review

• Activation of the MAP kinase pathway by the protein kinase raf

  Howe, L. R., Leevers, S. J., Gómez, N., Nakielny, S., Cohen, P. & Marshall, C. J., 16 Oct 1992, In: Cell. 71, 2, p. 335-342 8 p.

  Research output: Contribution to journal › Article › peer-review

  • raf Kinases 100%
  • Protein Kinases 88%
  • MAP Kinase Kinase Kinases 87%
  • Phosphotransferases 74%
  • Oncogenic 67%
  616 Citations (Scopus)

• Activation of the MAP kinase homologue RK requires the phosphorylation of Thr-180 and Tyr-182 and both residues are phosphorylated in chemically stressed KB cells

  Doza, Y. N., Cuenda, A., Thomas, G. M., Cohen, P. & Nebreda, A. R., 8 May 1995, In: FEBS Letters. 364, 2, p. 223-228 6 p.

  Research output: Contribution to journal › Article › peer-review

  • KB Cells 100%
  • Phosphotransferases 55%
  • Phosphorylation 49%
  • Enzyme Activation 30%
  70 Citations (Scopus)

• Activation of the E3 ligase function of the BRCA1/BARD1 complex by polyubiquitin chains

  Mallery, D. L., Vandenberg, C. J. & Hiom, K., 16 Dec 2002, In: EMBO Journal. 21, 24, p. 6755-6762 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Polyubiquitin 100%
  • Ubiquitin-Protein Ligases 78%
  • Histone 73%
  • Histones 42%
  • Ubiquitin Thiolesterase 36%
  225 Citations (Scopus)

• Activation of the cryptic DNA binding function of mutant forms of p53

  Hupp, T. R., Meek, D. W., Midgley, C. A. & Lane, D. P., 11 Jul 1993, In: Nucleic Acids Research. 21, 14, p. 3167-3174 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Casein Kinase II 100%
  • DNA 62%
  • Allosteric Regulation 55%
  • Multiprotein Complexes 49%
  • Post Translational Protein Processing 38%
  181 Citations (Scopus)

• Activation of the cardiac mTOR/p70(S6K) pathway by leucine requires PDK1 and correlates with PRAS40 phosphorylation

  Canedo, C. S., Demeulder, B., Ginion, A., Bayascas, J. R., Balligand, J-L., Alessi, D. R., Vanoverschelde, J-L., Beauloye, C., Hue, L. & Bertrand, L., Apr 2010, In: AJP - Endocrinology and Metabolism (Endocrinology and Metabolism. 298, 4, p. E761-E769 9 p.

  Research output: Contribution to journal › Article › peer-review

  • 70-kDa Ribosomal Protein S6 Kinases 100%
  • TOR Serine-Threonine Kinases 84%
  • Proline 80%
  • Phosphatidylinositols 80%
  • Leucine 77%
  46 Citations (Scopus)

• Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains

  Emmerich, C. H., Ordureau, A., Strickson, S., Arthur, J. S. C., Pedrioli, P. G. A., Komander, D. & Cohen, P., 17 Sep 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 38, p. 15247-15252 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Polyubiquitin 100%
  • Methionine 71%
  • Ubiquitin 68%
  • Phosphotransferases 10%
  • Transforming Growth Factor beta 9%
  254 Citations (Scopus)

  120 Downloads (Pure)

• Activation of stress-activated protein kinase-3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); Comparison of the specificities of SAPK3 and SAPK2 (RK/p38)

  Cuenda, A., Cohen, P., Buée-Scherrer, V. & Goedert, M., 15 Jan 1997, In: EMBO Journal. 16, 2, p. 295-305 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mitogen-Activated Protein Kinase 12 100%
  • Mitogen-Activated Protein Kinase 11 94%
  • Cytokines 32%
  • Protein 21%
  • Interleukin-1 10%
  309 Citations (Scopus)

• Activation of serum- and glucocorticoid-regulated protein kinase by agonists that activate phosphatidylinositide 3-kinase is mediated by 3-phosphoinositide-dependent protein kinase-1 (PDK1) and PDK2

  Kobayashi, T. & Cohen, P., 15 Apr 1999, In: Biochemical Journal. 339, 2, p. 319-328 10 p.

  Research output: Contribution to journal › Article › peer-review

  • serum-glucocorticoid regulated kinase 100%
  • 3-Phosphoinositide-Dependent Protein Kinases 97%
  • Agonist 55%
  • Protein Kinases 53%
  • Phosphotransferases 45%
  496 Citations (Scopus)