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• Yeast informs Alzheimer's disease

  McGurk, L. & Bonini, N. M., 2 Dec 2011, In: Science. 334, 6060, p. 1212-1213 2 p.

  Research output: Contribution to journal › Short survey › peer-review

  • Yeasts
  • Alzheimer Disease
  7 Citations (Scopus)

• Protein interacting with C kinase (PICK1) is a suppressor of spinocerebellar ataxia 3-associated neurodegeneration in Drosophila

  McGurk, L. & Bonini, N. M., 1 Jan 2012, In: Human Molecular Genetics. 21, 1, p. 76-84 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Machado-Joseph Disease
  • Protein Kinase C
  • Drosophila
  • polyglutamine
  • Phosphotransferases
  16 Citations (Scopus)

  63 Downloads (Pure)

• Poly(ADP-Ribose) Prevents Pathological Phase Separation of TDP-43 by Promoting Liquid Demixing and Stress Granule Localization

  McGurk, L., Gomes, E., Guo, L., Mojsilovic-Petrovic, J., Tran, V., Kalb, R. G., Shorter, J. & Bonini, N. M., 6 Sep 2018, In: Molecular Cell. 71, 5, p. 703-717.e9 24 p.

  Research output: Contribution to journal › Article › peer-review

  • Tankyrases
  • Poly Adenosine Diphosphate Ribose
  • Amyotrophic Lateral Sclerosis
  • Phosphorylation
  • Poly(ADP-ribose) Polymerases
  91 Citations (Scopus)

• Poly(ADP-ribose) Engages the TDP-43 Nuclear-Localization Sequence to Regulate Granulo-Filamentous Aggregation

  McGurk, L., Gomes, E., Guo, L., Shorter, J. & Bonini, N. M., 26 Dec 2018, In: Biochemistry. 57, 51, p. 6923-6926 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Poly Adenosine Diphosphate Ribose
  • Agglomeration
  • Prions
  • Biopolymers
  • DNA-Binding Proteins
  8 Citations (Scopus)

• Nuclear poly(ADP-ribose) activity is a therapeutic target in amyotrophic lateral sclerosis

  McGurk, L., Mojsilovic-Petrovic, J., Van Deerlin, V. M., Shorter, J., Kalb, R. G., Lee, V. M., Trojanowski, J. Q., Lee, E. B. & Bonini, N. M., 29 Aug 2018, In: Acta Neuropathologica Communications. 6, 1, p. 1-15 15 p., 84.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Poly Adenosine Diphosphate Ribose
  • Amyotrophic Lateral Sclerosis
  • veliparib
  • Spinal Cord
  • Nuclear RNA
  24 Citations (Scopus)

  70 Downloads (Pure)

• Functional conservation in human and Drosophila of Metazoan ADAR2 involved in RNA editing: Loss of ADAR1 in insects

  Keegan, L. P., McGurk, L., Palavicini, J. P., Brindle, J., Paro, S., Li, X., Rosenthal, J. J. C. & O'Connell, M. A., 1 Sep 2011, In: Nucleic Acids Research. 39, 16, p. 7249-7262 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • RNA Editing
  • Insecta
  • Drosophila
  • Vertebrates
  • Crustacea
  35 Citations (Scopus)

  80 Downloads (Pure)

• Drosophila as an in vivo model for human neurodegenerative disease

  McGurk, L., Berson, A. & Bonini, N. M., Oct 2015, In: Genetics. 201, 2, p. 377-402 26 p.

  Research output: Contribution to journal › Article › peer-review

  • Diptera
  • Drosophila
  • Neurodegenerative Diseases
  • Therapeutic Human Experimentation
  • polyglutamine
  121 Citations (Scopus)