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Author

  • Leeanne McGurk

Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila

Deng, P., Khan, A., Jacobson, D., Sambrani, N., McGurk, L., Li, X., Jayasree, A., Hejatko, J., Shohat-Ophir, G., O'Connell, M. A., Li, J. B. & Keegan, L. P., 27 Mar 2020, In : Nature Communications. 11, 1, p. 1580 1580.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
36 Downloads (Pure)

Drosophila as an in vivo model for human neurodegenerative disease

McGurk, L., Berson, A. & Bonini, N. M., Oct 2015, In : Genetics. 201, 2, p. 377-402 26 p.

Research output: Contribution to journalArticle

108 Citations (Scopus)

First person - Leeanne McGurk

McGurk, L., Jun 2020, In : Journal of Cell Science. 133, 12, 2 p., jcs.248773.

Research output: Contribution to journalComment/debate

Membrane and synaptic defects leading to neurodegeneration in Adar mutant Drosophila are rescued by increased autophagy

Khan, A., Paro, S., McGurk, L., Sambrani, N., Hogg, M. C., Brindle, J., Pennetta, G., Keegan, L. P. & O'Connell, M. A., 14 Feb 2020, In : BMC Biology. 18, 1, 16 p., 15.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
42 Downloads (Pure)

Poly(ADP-Ribosylation) in Age-Related Neurological Disease

McGurk, L., Rifai, O. M. & Bonini, N. M., Aug 2019, In : Trends in Genetics. 35, 8, p. 601-613 13 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)

Poly-A binding protein-1 localization to a subset of TDP-43 inclusions in amyotrophic lateral sclerosis occurs more frequently in patients harboring an expansion in C9orf72

McGurk, L., Lee, V. M., Trojanowksi, J. Q., Van Deerlin, V. M., Lee, E. B. & Bonini, N. M., 1 Sep 2014, In : Journal of Neuropathology and Experimental Neurology. 73, 9, p. 837-845 9 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)
Open Access
File
16 Citations (Scopus)
56 Downloads (Pure)

TDP-43, a protein central to amyotrophic lateral sclerosis, is destabilized by tankyrase-1 and -2

McGurk, L., Rifai, O. & Bonini, N. M., 23 Jun 2020, In : Journal of Cell Science. 133, 12

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
17 Downloads (Pure)

Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models

Kim, H. J., Raphael, A. R., Ladow, E. S., Mcgurk, L., Weber, R. A., Trojanowski, J. Q., Lee, V. M. Y., Finkbeiner, S., Gitler, A. D. & Bonini, N. M., Feb 2014, In : Nature Genetics. 46, 2, p. 152-160 9 p.

Research output: Contribution to journalArticle

199 Citations (Scopus)