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Cutting Edge: Building bridges between cellular and molecular structural biology
Patwardhan, A., Brandt, R., Butcher, S. J., Collinson, L., Gault, D., Grünewald, K., Hecksel, C., Huiskonen, J. T., Iudin, A., Jones, M. L., Korir, P. K., Koster, A. J., Lagerstedt, I., Lawson, C. L., Mastronarde, D., McCormick, M., Parkinson, H. E., Rosenthal, P. B., Saalfeld, S., Saibil, H. R. & 7 others, , 24 Jul 2017, In: eLife. 6, p. 1-11 11 p., e25835.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)144 Downloads (Pure) -
CXCL12 and C5a trigger cell migration via a PAK1/2-p38α MAPK-MAPKAP-K2-HSP27 pathway
Rousseau, S., Dolado, I., Beardmore, V., Shpiro, N., Marquez, R., Nebreda, A. R., Arthur, J. S. C., Case, L. M., Tessier-Lavigne, M., Gaestel, M., Cuenda, A. & Cohen, P., 1 Nov 2006, In: Cellular Signalling. 18, 11, p. 1897-1905 9 p.Research output: Contribution to journal › Article › peer-review
106 Citations (Scopus) -
CXCL-8-dependent and -independent neutrophil activation in COPD: experiences from a pilot study of the CXCR2 antagonist danirixin
Keir, H. R., Richardson, H., Fillmore, C., Shoemark, A., Lazaar, A. L., Miller, B. E., Tal-Singer, R., Chalmers, J. D. & Mohan, D., 10 Nov 2020, In: ERJ Open Research. 6, 4, 4 p., 00583-2020.Research output: Contribution to journal › Article › peer-review
Open AccessFile24 Downloads (Pure) -
Cyanobacterial effects in Lake Ludoš, Serbia - Is preservation of a degraded aquatic ecosystem justified?
Tokodi, N., Drobac, D., Meriluoto, J., Lujić, J., Marinović, Z., Važić, T., Nybom, S., Simeunović, J., Dulić, T., Lazić, G., Petrović, T., Vuković-Gačić, B., Sunjog, K., Kolarević, S., Kračun-Kolarević, M., Subakov-Simić, G., Miljanović, B., Codd, G. A. & Svirčev, Z., 1 Sep 2018, In: Science of the Total Environment. 635, p. 1047-1062 16 p.Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus) -
Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants
MacKintosh, C., Beattie, K. A., Klumpp, S., Cohen, P. & Codd, G. A., 1990, In: FEBS Letters. 264, 2, p. 187-192 6 p.Research output: Contribution to journal › Article › peer-review
1365 Citations (Scopus) -
Cyanobacterial toxins: Occurrence, properties and biological significance
Codd, G. A., 1995, In: Water Science and Technology. 32, 4, p. 149-156 8 p.Research output: Contribution to journal › Article › peer-review
325 Citations (Scopus) -
Cyanobacterial toxins: risk management for health protection
Codd, G. A., Morrison, L. F. & Metcalf, J. S., Mar 2005, In: Toxicology and Applied Pharmacology. 203, 3, p. 264-272 9 p.Research output: Contribution to journal › Article › peer-review
858 Citations (Scopus) -
Cyanobacteria vs green algae: which group has the edge?
Beardall, J. & Raven, J. A., 8 Sep 2017, In: Journal of Experimental Botany. 68, 14, p. 3697-3699 3 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)144 Downloads (Pure) -
Cyanotoxins in desert environments may present a risk to human health
Metcalf, J. S., Richer, R., Cox, P. A. & Codd, G. A., 1 Apr 2012, In: Science of the Total Environment. 421, p. 118-123 6 p.Research output: Contribution to journal › Article › peer-review
86 Citations (Scopus) -
Cycles of Identity Formation in Interorganizational Collaborations
Beech, N., 2003, In: International Studies of Management and Organization. p. 28-52 25 p.Research output: Contribution to journal › Article › peer-review
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Cyclic AMP Effectors in African Trypanosomes Revealed by Genome-Scale RNA Interference Library Screening for Resistance to the Phosphodiesterase Inhibitor CpdA
Gould, M. K., Bachmaier, S., Ali, J. A. M., Alsford, S., Tagoe, D. N. A., Munday, J. C., Schnaufer, A. C., Horn, D., Boshart, M. & de Koning, H. P., Oct 2013, In: Antimicrobial Agents and Chemotherapy. 57, 10, p. 4882-4893 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile41 Citations (Scopus)20 Downloads (Pure) -
Cyclic AMP induction of Dictyostelium prespore gene expression requires autophagy
Yamada, Y. & Schaap, P., 15 Aug 2019, In: Developmental Biology. 452, 2, p. 114-126 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)99 Downloads (Pure) -
Cyclic AMP regulates a calcium-activated non-selective cation channel in a rat insulinoma cell line
Reale, V., Hales, C. N. & Ashford, M. L. J., 30 Mar 1992, In: Journal of Physiology. 446Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
Cyclic and Fatigue Behaviour of Rock Materials: Review, Interpretation and Research Perspectives
Cerfontaine, B. & Collin, F., 1 Feb 2018, In: Rock Mechanics and Rock Engineering. 51, 2, p. 391-414 24 p.Research output: Contribution to journal › Article › peer-review
142 Citations (Scopus) -
Cyclic and macrocyclic peptides as chemical tools to recognise protein surfaces and probe protein-protein interactions
Cardote, T. A. F. & Ciulli, A., 19 Apr 2016, In: ChemMedChem. 11, 8, p. 787-794 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile108 Citations (Scopus)157 Downloads (Pure) -
Cyclic change of server's performance: Impacts and applications
Huang, B., Xie, J. & He, Q. M., Mar 2014, In: IEEE Transactions on Automatic Control. 59, 3, p. 703-713 11 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Cyclic-di-adenosine monophosphate (c-di-AMP) is required for osmotic regulation in Staphylococcus aureus but dispensable for viability in anaerobic conditions
Zeden, M. S., Schuster, C. F., Bowman, L., Zhong, Q., Williams, H. D. & Gründling, A., 2 Mar 2018, In: Journal of Biological Chemistry. 293, 9, p. 3180-3200 21 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile49 Citations (Scopus)165 Downloads (Pure) -
Cyclic di-GMP signalling and the regulation of bacterial virulence
Ryan, R. P., Jul 2013, In: Microbiology. 159, 7, p. 1286-1297 12 p.Research output: Contribution to journal › Article › peer-review
64 Citations (Scopus) -
Cyclic Nrarp mRNA expression is regulated by the somitic oscillator but Nrarp protein levels do not oscillate
Wright, D., Ferjentsik, Z., Chong, S-W., Qiu, X., Jiang, Y-J., Malapert, P., Pourquie, O., Van Hateren, N., Wilson, S. A., Franco, C., Gerhardt, H., Dale, J. K. & Maroto, M., Dec 2009, In: Developmental Dynamics. 238, 12, p. 3043-3055 13 p.Research output: Contribution to journal › Article › peer-review
16 Citations (Scopus) -
Cyclin A triggers Mitosis either via the Greatwall kinase pathway or Cyclin B
Hegarat, N., Crncec, A., Suarez Peredoa Rodriguez, M. F., Iturra, F. E., Gu, Y., Busby, O., Lang, P. F., Barr, A. R., Bakal, C., Kanemaki, M. T., Lamond, A. I., Novak, B., Ly, T. & Hochegger, H., 2 Jun 2020, In: EMBO Journal. 39, 11, 23 p., e104419.Research output: Contribution to journal › Article › peer-review
Open AccessFile24 Citations (Scopus)82 Downloads (Pure) -
Cyclin B1 is localized to unattached kinetochores and contributes to efficient microtubule attachment and proper chromosome alignment during mitosis
Chen, Q., Zhang, X., Jiang, Q., Clarke, P. R. & Zhang, C., Feb 2008, In: Cell Research. 18, 2, p. 268-280 13 p.Research output: Contribution to journal › Article › peer-review
55 Citations (Scopus) -
Cyclin B1 scaffolds MAD1 at the kinetochore corona to activate the mitotic checkpoint
Allan, L. A., Reis, M. C., Ciossani, G., Huigs in ‘t Veld, P. J., Wohlgemuth, S., Kops, G. J. P. L., Musacchio, A. & Saurin, A. T., 17 Jun 2020, In: EMBO Journal. 39, 12, 16 p., e103180.Research output: Contribution to journal › Article › peer-review
Open AccessFile21 Citations (Scopus)157 Downloads (Pure) -
Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis
Wyllie, S., Thomas, M., Patterson, S., Crouch, S., De Rycker, M., Lowe, R., Gresham, S., Urbaniak, M. D., Otto, T. D., Stojanovski, L., Simeons, F. R. C., Manthri, S., MacLean, L. M., Zuccotto, F., Homeyer, N., Pflaumer, H., Boesche, M., Sastry, L., Connolly, P., Albrecht, S. & 12 others, , 9 Aug 2018, In: Nature. 560, 7717, p. 192-197 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile72 Citations (Scopus)546 Downloads (Pure) -
Cyclin-Dependent Kinases: CAK-handed kinase activation
Clarke, P. R., 1 Jan 1995, In: Current Biology. 5, 1, p. 40-42 3 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Citations (Scopus) -
Cycling injuries requiring orthopaedic intervention during the first COVID-19 lockdown period: A multi-centre SCottish Orthopaedic Research collaborativE (SCORE) study
Faulkner, A., MacDonald, D. R. W., Neilly, D. W., Davies, P. S. E., Ha, T. T., Stevenson, I. M., Jariwala, A. C., Donoghue, C. J., Lee, A., Bashyam, J., Greensmith, T. S., Macinnes, A., Pennington, R., Sinnerton, R., Supparamaniam, S., Crome, C. R., Guiot, L., Harte, C., Kennedy, M. J., Noteman, T. W. & 7 others, , 26 Jun 2021, (E-pub ahead of print) In: Surgeon. 6 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Cycloalkane-modified amphiphilic polymers provide direct extraction of membrane proteins for CryoEM analysis
Higgins, A. J., Flynn, A. J., Marconnet, A., Musgrove, L. J., Postis, V. L. G., Lippiat, J. D., Chung, C., Ceska, T., Zoonens, M., Sobott, F. & Muench, S. P., 25 Nov 2021, In: Communications Biology. 4, 9 p., 1337.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)22 Downloads (Pure) -
Cyclobutane pyrimidine dimers are photosensitised by carprofen plus UVA in human HaCaT cells
Robinson, K. S., Traynor, N. J., Moseley, H., Ferguson, J. & Woods, J. A., Jun 2010, In: Toxicology in Vitro. 24, 4, p. 1126-1132 7 p.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus) -
Cyclooxygenase-1 is a marker for a subpopulation of putative nociceptive neurons in rat dorsal root ganglia
Chopra, B., Giblett, S., Little, J. G., Donaldson, L. F., Tate, S., Evans, R. J. & Grubb, B. D., 24 Dec 2001, In: European Journal of Neuroscience. 12, 3, p. 911-920 10 p.Research output: Contribution to journal › Article › peer-review
66 Citations (Scopus) -
Cyclosporin-induced hypertension precedes renal dysfunction and sodium retention in man
Sturrock, N. D. C., Lang, C. C. & Struthers, A. D., 1993, In: Journal of Hypertension. 11, 11, p. 1209-1216 8 p.Research output: Contribution to journal › Article › peer-review
40 Citations (Scopus) -
Cyclosporin-induced nephrotoxicity and hypertension
Sturrock, N. D., Lang, C. C. & Struthers, A. D., 1992, In: British Journal of Hospital Medicine. 48, 8, p. 483-485, 488-489 5 p.Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus) -
Cyclosporin-induced renal vasoconstriction is augmented by frusemide and by angiotensin II in humans
Sturrock, N. D. C., Lang, C. C., Coutie, W. J. & Struthers, A. D., 1995, In: Journal of Hypertension. 13, 9, p. 987-991 5 p.Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus) -
CYP2B6 and OPRM1 gene variations predict methadone-related deaths
Bunten, H., Liang, W-J., Pounder, D., Seneviratne, C. & Osselton, M. D., Jan 2011, In: Addiction Biology. 16, 1, p. 142-144 3 p.Research output: Contribution to journal › Article › peer-review
54 Citations (Scopus) -
Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans
Takahashi, S., Fukami, T., Masuo, Y., Brocker, C. N., Xie, C., Krausz, K. W., Wolf, C. R., Henderson, C. J. & Gonzalez, F. J., Dec 2016, In: Journal of Lipid Research. 57, p. 2130-2037 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile137 Citations (Scopus)213 Downloads (Pure) -
CYP2C8 and SLCO1B1 variants and therapeutic response to thiazolidinediones in patients with type 2 diabetes.
Dawed, A. Y., Donnelly, L., Tavendale, R., Carr, F., Leese, G., Palmer, C. N. A., Pearson, E. & Zhou, K., Nov 2016, In: Diabetes Care. 39, 11, p. 1902-1908 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile39 Citations (Scopus)221 Downloads (Pure) -
CYP2D6 genotype and adjuvant tamoxifen: meta-analysis of heterogeneous study populations
Province, M. A., Goetz, M. P., Brauch, H., Flockhart, D. A., Hebert, J. M., Whaley, R., Suman, V. J., Schroth, W., Winter, S., Zembutsu, H., Mushiroda, T., Newman, W. G., Lee, M-T. M., Ambrosone, C. B., Beckmann, M. W., Choi, J-Y., Dieudonné, A-S., Fasching, P. A., Ferraldeschi, R., Gong, L. & 34 others, , Feb 2014, In: Clinical Pharmacology & Therapeutics. 95, 2, p. 216-227 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile139 Citations (Scopus)152 Downloads (Pure) -
CYP3A4 active site volume modification by mutagenesis of leucine 211
Fowler, S. M., Taylor, J. M., Friedberg, T., Roland Wolf, C. & Riley, R. J., 10 Apr 2002, In: Drug Metabolism and Disposition. 30, 4, p. 452-456 5 p.Research output: Contribution to journal › Article › peer-review
Open Access25 Citations (Scopus) -
Cystatin F Ensures Eosinophil Survival by Regulating Granule Biogenesis
Matthews, S. P., McMillan, S. J., Colbert, J. D., Lawrence, R. A. & Watts, C., 19 Apr 2016, In: Immunity. 44, 4, p. 795-806 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile27 Citations (Scopus)165 Downloads (Pure) -
Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysis
Hamilton, G., Colbert, J. D., Schuettelkopf, A. W. & Watts, C., 6 Feb 2008, In: EMBO Journal. 27, 3, p. 499-508 10 p.Research output: Contribution to journal › Article › peer-review
81 Citations (Scopus) -
Cystatin F Regulates Proteinase Activity in IL-2-activated Natural Killer Cells
Maher, K., Konjar, S., Watts, C., Turk, B. & Kopitar-Jerala, N., Sep 2014, In: Protein and Peptide Letters. 21, 9, p. 957-965 9 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
Cysteine eliminates the feeder cell requirement for cultivation of Trypanosoma brucei bloodstream forms in vitro
Duszenko, M., Ferguson, M. A. J., Lamont, G. S., Rifkin, M. R. & Cross, G. A., 1 Oct 1985, In: Journal of Experimental Medicine. 162, 4, p. 1256-1263 8 p.Research output: Contribution to journal › Article › peer-review
78 Citations (Scopus) -
Cysteine residues 244 and 458-459 within the catalytic subunit of Na,K-ATPase control the enzyme's hydrolytic and signaling function under hypoxic conditions
Petrushanko, I. Y., Mitkevich, V. A., Lakunina, V. A., Anashkina, A. A., Spirin, P. V., Rubtsov, P. M., Prassolov, V. S., Bogdanov, N. B., Hänggi, P., Fuller, W., Makarov, A. & Bogdanova, A., Oct 2017, In: Redox Biology. 13, p. 310-319 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)140 Downloads (Pure) -
Cysteine-scanning mutagenesis and disulfide mapping studies of the conserved domain of the twin-arginine translocase TatB component
Lee, P. A., Orriss, G. L., Buchanan, G., Greene, N. P., Bond, P. J., Punginelli, C., Jack, R. L., Sansom, M. S. P., Berks, B. C. & Palmer, T., 2006, In: Journal of Biological Chemistry. 281, 45, p. 34072-34085 14 p.Research output: Contribution to journal › Article › peer-review
50 Citations (Scopus) -
Cysteine scanning mutagenesis and disulfide mapping studies of the TatA component of the bacterial twin arginine translocase
Greene, N. P., Porcelli, I., Buchanan, G., Hicks, M. G., Schermann, S. M., Palmer, T. & Berks, B. C., 2007, In: Journal of Biological Chemistry. 282, 33, p. 23937-23945 9 p.Research output: Contribution to journal › Article › peer-review
44 Citations (Scopus) -
Cysteine scanning mutagenesis and topological mapping of the Escherichia coli twin-arginine translocase TatC component
Punginelli, C., Maldonado, B., Grahl, S., Jack, R., Alami, M., Schroeder, J., Berks, B. C. & Palmer, T., 2007, In: Journal of Bacteriology. 189, 15, p. 5482-5494 13 p.Research output: Contribution to journal › Article › peer-review
37 Citations (Scopus) -
Cystic Fibrosis: A Pocket Guide
Roughley, M., MacDougall, L. & Erolin, C., 2020, In: Journal of Visual Communication in Medicine. 43, 4, p. 198-210 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Downloads (Pure) -
Cystic fibrosis across Europe: EuroCareCF analysis of demographic data from 35 countries
Mehta, G., Macek, M., Mehta, A. & European Registry Working Grp, Dec 2010, In: Journal of Cystic Fibrosis. 9, S2, p. S5-S21 17 p.Research output: Contribution to journal › Article › peer-review
76 Citations (Scopus) -
Cystic fibrosis as a bowel cancer syndrome and the potential role of CK2
Mehta, A., Sep 2008, In: Molecular and Cellular Biochemistry. 316, 1-2, p. 169-175 7 p.Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus) -
Cystic fibrosis diagnosed after 2 months of age leads to worse outcomes and requires more therapy
Sims, E. J., Clark, A., McCormick, J., Mehta, G., Connett, G. & Mehta, A., 2007, In: Pediatrics. 119, 1, p. 19-28 10 p.Research output: Contribution to journal › Article › peer-review
105 Citations (Scopus) -
Cystic fibrosis in the mouse by targeted insertional mutagenesis
Dorin, J. R., Dickinson, P., Alton, E. W., Smith, S. N., Geddes, D. M., Stevenson, B. J., Kimber, W. L., Fleming, S., Clarke, A. R. & Hooper, M. L., 1992, In: Nature. 359, 6392, p. 211-5 5 p.Research output: Contribution to journal › Article › peer-review
236 Citations (Scopus) -
Cystic fibrosis transmembrane regulator fragments with the Phe(508) deletion exert a dual allosteric control over the master kinase CK2
Pagano, M. A., Marin, O., Cozza, G., Sarno, S., Meggio, F., Treharne, K. J., Mehta, A. & Pinna, L. A., 15 Feb 2010, In: Biochemical Journal. 426, 1, p. 19-29 11 p.Research output: Contribution to journal › Article › peer-review
23 Citations (Scopus)