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• Article

  Disclosure of records and privacy rights in rape cases

  Raitt, F. E., May 2011, In: Edinburgh Law Review. 15, 1, p. 33-56 24 p.

  Research output: Contribution to journal › Article › peer-review

• Disclosure patterns in derivatives reporting by UK firms: Implications for corporate governance

  Dunne, T., Fox, A. & Helliar, C., 2007, In: International Journal of Accounting, Auditing and Performance Evaluation. 4, 3, p. 231-247 17 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Disconnect between standardized field-based testing and mannitol challenge in Scottish elite swimmers

  Clearie, K. L., Williamson, P. A., Vaidyanathan, S., Short, P., Goudie, A., Burns, P., Hopkinson, P., Meldrum, K., Howaniec, L. & Lipworth, B. J., May 2010, In: Clinical and Experimental Allergy. 40, 5, p. 731-737 7 p.

  Research output: Contribution to journal › Article › peer-review
  19 Citations (Scopus)

• Disconnection of pulmonary and systemic arterial stiffness in COPD

  Weir-McCall, J. R., Liu-Shiu-Cheong, P. S., Struthers, A. D., Lipworth, B. J. & Houston, J. G., 28 May 2018, In: International Journal of Chronic Obstructive Pulmonary Disease. 13, p. 1755-1765 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  2 Citations (Scopus)

  124 Downloads (Pure)

• Discontinuation of beta-blockers in cardiovascular disease: UK primary care cohort study

  Kalra, P. R., Morley, C., Barnes, S., Menown, I., Kassianos, G., Padmanabhan, S., Gupta, S. & Lang, C. C., 2012, In: International Journal of Cardiology. 167, 6, p. 2695-2699 5 p.

  Research output: Contribution to journal › Article › peer-review
  22 Citations (Scopus)

• Discordant fandom and global football brands: ‘Let the people sing’

  Hewer, P., Gannon, M. & Cordina, R., 1 Nov 2017, In: Journal of Consumer Culture. 17, 3, p. 600-619 20 p.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• Discourse analysis and pragmatics in the design of a conversation prosthesis

  Alm, N., Arnott, J. L. & Newell, A. F., 1989, In: Journal of Medical Engineering and Technology. 13, 1-2, p. 10-12 3 p.

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)

• Discourse-mediation of the mapping between language and the visual world: Eye movements and mental representation

  Altmann, G. T. M. & Kamide, Y., Apr 2009, In: Cognition. 111, 1, p. 55-71 17 p.

  Research output: Contribution to journal › Article › peer-review
  117 Citations (Scopus)

• Discourses and practices in teaching methods and assessment: insights from an early career academic

  Gopinath, D., 3 Mar 2015, In: SAGE Open . 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  103 Downloads (Pure)

• Discourses of citizenship in transition: Scale, politics and urban renewal

  Smith, F. M., 1 Jan 1999, In: Urban Studies. 36, 1, p. 167-187 21 p.

  Research output: Contribution to journal › Article › peer-review
  19 Citations (Scopus)

• Discourses of disrupted identities in the practice of strategic change: The mayor, the street-fighter and the insider-out

  Beech, N. & Johnson, P., 2005, In: Journal of Organizational Change Management. 18, 1, p. 31-47 17 p.

  Research output: Contribution to journal › Article › peer-review
  49 Citations (Scopus)

• Discovery, in vivo activity and mechanism of action of a small-molecule p53 activator

  Lain, S., Hollick, J. J., Campbell, J., Staples, O. D., Higgins, M., Aoubala, M., McCarthy, A., Appleyard, V., Murray, K. E., Baker, L., Thompson, A., Mathers, J., Holland, S. J., Stark, M. J. R., Pass, G., Woods, J., Lane, D. P. & Westwood, N. J., 6 May 2008, In: Cancer Cell. 13, 5, p. 454-463 10 p.

  Research output: Contribution to journal › Article › peer-review
  393 Citations (Scopus)

• Discovery and Characterization of Selective and Ligand-Efficient DYRK Inhibitors

  Henderson, S. H., Sorrell, F., Bennett, J., Fedorov, O., Hanley, M. T., Godoi, P. H., Ruela de Sousa, R., Robinson, S., Ashall-Kelly, A., Hopkins Navratilova, I., Walter, D. S., Elkins, J. M. & Ward, S. E., 12 Aug 2021, In: Journal of Medicinal Chemistry. 64, 15, p. 11709-11728 20 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  1 Downloads (Pure)

• Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability

  Kwasna, D., Rehman, S. A. A., Natarajan, J., Matthews, S., Madden, R., De Cesare, V., Weidlich, S., Virdee, S., Ahel, I., Gibbs-Seymour, I. & Kulathu, Y., 5 Apr 2018, In: Molecular Cell. 70, 1, p. 150-164.e6 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  68 Citations (Scopus)

  140 Downloads (Pure)

• Discovery and development of Seliciclib. How systems biology approaches can lead to better drug performance

  Khalil, H. S., Mitev, V., Vlaykova, T., Cavicchi, L. & Zhelev, N., 20 May 2015, In: Journal of Biotechnology. 202, p. 40-49 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  30 Citations (Scopus)

  51 Downloads (Pure)

• Discovery and Differential Processing of HLA Class II-Restricted Minor Histocompatibility Antigen LB-PIP4K2A-1S and Its Allelic Variant by Asparagine Endopeptidase

  Kremer, A. N., Bausenwein, J., Lurvink, E., Kremer, A. E., Rutten, C. E., van Bergen, C. A. M., Kretschmann, S., van der Meijden, E., Honders, M. W., Mazzeo, D., Watts, C., Mackensen, A., Falkenburg, J. H. F. & Griffioen, M., 11 Mar 2020, In: Frontiers in Immunology. 11, 11 p., 381.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  3 Citations (Scopus)

  16 Downloads (Pure)

• Discovery and observations of ASASSN-13db, an EX lupi-type accretion event on a low-mass T tauri star

  Holoien, T. W. S., Prieto, J. L., Stanek, K. Z., Kochanek, C. S., Shappee, B. J., Zhu, Z., Sicilia-Aguilar, A., Grupe, D., Croxall, K., Adams, D. J., Simon, J. D., Morrell, N. W., McGraw, S. M., Wagner, R. M., Basu, U., Beacom, J. F., Bersier, D., Brimacombe, J., Jencson, J., Pojmanski, G. & 3 others, Starrfield, S. G., Szczygie, D. M. & Woodward, C. E., 20 Apr 2014, In: Astrophysical Journal Letters. 785, 2, 6 p., L35.

  Research output: Contribution to journal › Article › peer-review
  23 Citations (Scopus)

• Discovery and Optimisation of a Compound Series active against Trypanosoma cruzi, the causative agent of Chagas’ Disease

  Harrison, J. R., Sarkar, S., Hampton, S., Riley, J., Stojanovski, L., Sahlberg, C., Appelqvist, P., Erath, J., Mathan, V., Rodriguez, A., Kaiser, M., Pacanowska, D. G., Read, K. D., Johansson, N. G. & Gilbert, I. H., 26 Mar 2020, In: Journal of Medicinal Chemistry. 63, 6, p. 3066-3089 24 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  1 Citation (Scopus)

  8 Downloads (Pure)

• Discovery and optimisation studies of antimalarial phenotypic hits

  Mital, A., Murugesan, D., Kaiser, M., Yeates, C. & Gilbert, I. H., 20 Oct 2015, In: European Journal of Medicinal Chemistry. 103, p. 530-538 9 p.

  Research output: Contribution to journal › Article › peer-review
  14 Citations (Scopus)

• Discovery and Optimization of 5-Amino-1,2,3-triazole-4-carboxamide Series against Trypanosoma cruzi

  Brand, S., Ko, E. J., Viayna, E., Thompson, S., Spinks, D., Thomas, M., Sandberg, L., Francisco, A. F., Jayawardhana, S., Smith, V. C., Jansen, C., De Rycker, M., Thomas, J., MacLean, L., Osuna-Cabello, M., Riley, J., Scullion, P., Stojanovski, L., Simeons, F. R. C., Epemolu, O. & 16 others, Shishikura, Y., Crouch, S. D., Bakshi, T. S., Nixon, C. J., Reid, I. H., Hill, A. P., Underwood, T. Z., Hindley, S. J., Robinson, S. A., Kelly, J. M., Fiandor, J. M., Wyatt, P. G., Marco, M., Miles, T. J., Read, K. D. & Gilbert, I. H., 14 Sep 2017, In: Journal of Medicinal Chemistry. 60, 17, p. 7284-7299 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  21 Citations (Scopus)

  164 Downloads (Pure)

• Discovery and profiling of small RNAs responsive to stress conditions in the plant pathogen Pectobacterium atrosepticum

  Kwenda, S., Gorshkov, V., Ramesh, A. M., Naidoo, S., Rubagotti, E., Birch, P. R. J. & Moleleki, L. N., 12 Jan 2016, In: BMC Genomics. 17, 15 p., 47.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  14 Citations (Scopus)

  124 Downloads (Pure)

• Discovery and refinement of loci associated with lipid levels

  Global Lipids Genetics Consortium, 2013, In: Nature Genetics. 45, 11, p. 1274-1283 10 p.

  Research output: Contribution to journal › Article › peer-review
  1546 Citations (Scopus)

• Discovery and structure-activity relationships of pyrrolone antimalarials

  Murugesan, D., Mital, A., Kaiser, M., Shackleford, D. M., Morizzi, J., Katneni, K., Campbell, M., Hudson, A., Charman, S. A., Yeates, C. & Gilbert, I. H., 2013, In: Journal of Medicinal Chemistry. 56, 7, p. 2975-2990 16 p.

  Research output: Contribution to journal › Article › peer-review
  41 Citations (Scopus)

• Discovery and Validation of SIRT2 Inhibitors Based on Tenovin-6: Use of a H-1-NMR Method to Assess Deacetylase Activity

  Pirrie, L., McCarthy, A. R., Major, L. L., Morkunaite, V., Zubriene, A., Matulis, D., Lain, S., Lebl, T. & Westwood, N. J., 2012, In: Molecules and Cells. 17, 10, p. 12206-12224 19 p.

  Research output: Contribution to journal › Article › peer-review
  8 Citations (Scopus)

• Discovery of 2-[1-(4,4-Difluorocyclohexyl)piperidin-4-yl]-6-fluoro-3-oxo-2,3-dihydro-1H-isoindole-4-carboxamide (NMS-P118): a potent, orally available, and highly selective PARP-1 inhibitor for cancer therapy

  Papeo, G., Posteri, H., Borghi, D., Busel, A. A., Caprera, F., Casale, E., Ciomei, M., Cirla, A., Corti, E., D'Anello, M., Fasolini, M., Forte, B., Galvani, A., Isacchi, A., Khvat, A., Krasavin, M. Y., Lupi, R., Orsini, P., Perego, R., Pesenti, E. & 9 others, Pezzetta, D., Rainoldi, S., Riccardi-Sirtori, F., Scolaro, A., Sola, F., Zuccotto, F., Felder, E. R., Donati, D. & Montagnoli, A., 10 Sep 2015, In: Journal of Medicinal Chemistry. 58, 17, p. 6875-6898 24 p.

  Research output: Contribution to journal › Article › peer-review
  64 Citations (Scopus)

• Discovery of 2-iminobenzimidazoles as a new class of trypanothione reductase inhibitor by high-throughput screening

  Holloway, G. A., Baell, J. B., Fairlamb, A. H., Novello, P. M., Parisot, J. P., Richardson, J., Watson, K. G. & Street, I. P., 1 Mar 2007, In: Bioorganic and Medicinal Chemistry Letters. 17, 5, p. 1422-1427 6 p.

  Research output: Contribution to journal › Article › peer-review
  47 Citations (Scopus)

• Discovery of A Ca2+-and calmodulin-dependent protein phosphatase

  Stewart, A. A., Ingebritsen, T. S., Manalan, A., Klee, C. B. & Cohen, P., 11 Jan 1982, In: FEBS Letters. 137, 1, p. 80-84 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  333 Citations (Scopus)

• Discovery of an Allosteric Binding Site in Kinetoplastid Methionyl-tRNA Synthetase

  Torrie, L. S., Robinson, D. A., Thomas, M. G., Hobrath, J. V., Shepherd, S. M., Post, J. M., Ko, E. J., Ferreira, R. A., Mackenzie, C. J., Wrobel, K., Edwards, D. P., Gilbert, I. H., Gray, D. W., Fairlamb, A. H. & De Rycker, M., 8 May 2020, In: ACS Infectious Diseases. 6, 5, p. 1044-1057 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  3 Citations (Scopus)

  29 Downloads (Pure)

• Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-acyl-ACP Reductase from Pseudomonas aeruginosa

  Cukier, C. D., Hope, A. G., Elamin, A. A., Moynie, L., Schnell, R., Schach, S., Kneuper, H., Singh, M., Naismith, J. H., Lindqvist, Y., Gray, D. W. & Schneider, G., 2013, In: ACS Chemical Biology. n/a, cb4005063.

  Research output: Contribution to journal › Article › peer-review
  22 Citations (Scopus)

• Discovery of a new sialic acid binding region that regulates Siglec-7

  Yamakawa, N., Yasuda, Y., Yoshimura, A., Goshima, A., Crocker, P. R., Vergoten, G., Nishiura, Y., Takahashi, T., Hanashima, S., Matsumoto, K., Yamaguchi, Y., Tanaka, H., Kitajima, K. & Sato, C., 26 May 2020, In: Scientific Reports. 10, 14 p., 8647.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  5 Citations (Scopus)

  17 Downloads (Pure)

• Discovery of a Novel Class of Orally Active Trypanocidal N-Myristoyltransferase Inhibitors

  Brand, S., Cleghorn, L. A. T., McElroy, S. P., Robinson, D. A., Smith, V. C., Hallyburton, I., Harrison, J. R., Norcross, N. R., Spinks, D., Bayliss, T., Norval, S., Stojanovski, L., Torrie, L. S., Frearson, J. A., Brenk, R., Fairlamb, A. H., Ferguson, M. A. J., Read, K. D., Wyatt, P. G. & Gilbert, I. H., 12 Jan 2012, In: Journal of Medicinal Chemistry. 55, 1, p. 140-152 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  87 Citations (Scopus)

  429 Downloads (Pure)

• Discovery of an RmlC/D fusion protein in the microalga Prymnesium parvum and its implications for NDP-β-L-rhamnose biosynthesis in microalgae

  Wagstaff, B., Rejzek, M., Kuhaudomlarp, S., Hill, L., Mascia, I., Nepogodiev, S. A., Dorfmueller, H. & Field, R. A., 7 Jun 2019, In: Journal of Biological Chemistry. 294, 23, p. 9172-9185 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  4 Citations (Scopus)

  108 Downloads (Pure)

• Discovery of an unconventional centromere in budding yeast redefines evolution of point centromeres

  Kobayashi, N., Suzuki, Y., Schoenfeld, L., Müller, C., Nieduszynski, C., Wolfe, K. & Tanaka, T., 3 Aug 2015, In: Current Biology. 25, 15, p. 2026-2033 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  26 Citations (Scopus)

  174 Downloads (Pure)

• Discovery of a protein phosphatase activity encoded in the genome of bacteriophage lambda. Probable identity with open reading frame 221.

  Cohen, P. T. & Cohen, P., 15 Jun 1989, In: The Biochemical journal. 260, 3, p. 931-934 4 p.

  Research output: Contribution to journal › Article › peer-review
  91 Citations (Scopus)

• Discovery of a pyrrolopyrimidine (JH-II-127), a highly potent, selective, and brain penetrant LRRK2 inhibitor

  Hatcher, J. M., Zhang, J., Choi, H. G., Ito, G., Alessi, D. R. & Gray, N. S., 14 May 2015, In: ACS Medicinal Chemistry Letters. 6, 5, p. 584-589 6 p.

  Research output: Contribution to journal › Article › peer-review
  30 Citations (Scopus)

• Discovery of a quinoline-4-carboxamide derivative with a novel mechanism of action, multistage antimalarial activity, and potent in vivo efficacy

  Baragaña, B., Norcross, N. R., Wilson, C., Porzelle, A., Hallyburton, I., Grimaldi, R., Osuna-Cabello, M., Norval, S., Riley, J., Stojanovski, L., Simeons, F. R. C., Wyatt, P. G., Delves, M. J., Meister, S., Duffy, S., Avery, V. M., Winzeler, E. A., Sinden, R. E., Wittlin, S., Frearson, J. A. & 7 others, Gray, D. W., Fairlamb, A. H., Waterson, D., Campbell, S. F., Willis, P., Read, K. D. & Gilbert, I. H., 10 Nov 2016, In: Journal of Medicinal Chemistry. 59, 21, p. 9672-9685 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  33 Citations (Scopus)

  181 Downloads (Pure)

• Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium

  Koivula, R. W., Heggie, A., Barnett, A., Cederberg, H., Hansen, T. H., Koopman, A. D., Ridderstråle, M., Rutters, F., Vestergaard, H., Gupta, R., Herrgård, S., Heymans, M. W., Perry, M. H., Rauh, S., Siloaho, M., Teare, H. J. A., Thorand, B., Bell, J., Brunak, S., Frost, G. & 14 others, Jablonka, B., Mari, A., McDonald, T. J., Dekker, J. M., Hansen, T., Hattersley, A., Laakso, M., Pedersen, O., Koivisto, V., Ruetten, H., Walker, M., Pearson, E., Franks, P. W. & DIRECT Consortium, Jun 2014, In: Diabetologia. 57, 6, p. 1132-1142 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  33 Citations (Scopus)

  169 Downloads (Pure)

• Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium

  Koivula, R. W., Forgie, I. M., Kurbasic, A., Viñuela, A., Heggie, A., Giordano, G. N., Hansen, T. H., Hudson, M., Koopman, A. D. M., Rutters, F., Siloaho, M., Allin, K. H., Brage, S., Brorsson, C. A., Dawed, A. Y., De Masi, F., Groves, C. J., Kokkola, T., Mahajan, A., Perry, M. H. & 30 others, Rauh, S. P., Ridderstråle, M., Teare, H. J. A., Thomas, E. L., Tura, A., Vestergaard, H., White, T., Adamski, J., Bell, J. D., Beulens, J. W., Brunak, S., Dermitzakis, E. T., Froguel, P., Frost, G., Gupta, R., Hansen, T., Hattersley, A., Jablonka, B., Kaye, J., Laakso, M., McDonald, T. J., Pedersen, O., Schwenk, J. M., Pavo, I., Mari, A., McCarthy, M. I., Ruetten, H., Walker, M., Pearson, E. & Franks, P. W., 1 Sep 2019, In: Diabetologia. 62, 9, p. 1601-1615 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  10 Citations (Scopus)

  11 Downloads (Pure)

• Discovery of catalytically active orthologues of the Parkinson's disease kinase PINK1: Analysis of substrate specificity and impact of mutations

  Woodroof, H. I., Pogson, J. H., Begley, M., Cantley, L. C., Deak, M., Campbell, D. G., Van Aalten, D. M. F., Whitworth, A. J., Alessi, D. R. & Muqit, M. M. K., 1 Nov 2011, In: Open Biology. 1, NOVEMBER, 110012.

  Research output: Contribution to journal › Article › peer-review
  65 Citations (Scopus)

• Discovery of common and rare genetic risk variants for colorectal cancer

  Huyghe, J. R., Bien, S. A., Harrison, T. A., Kang, H. M., Chen, S., Schmit, S. L., Conti, D. V., Qu, C., Jeon, J., Edlund, C. K., Greenside, P., Wainberg, M., Schumacher, F. R., Smith, J. D., Levine, D. M., Nelson, S. C., Sinnott-Armstrong, N. A., Albanes, D., Alonso, M. H., Anderson, K. & 179 others, Arnau-Collell, C., Arndt, V., Bamia, C., Banbury, B. L., Baron, J. A., Berndt, S. I., Bézieau, S., Bishop, D. T., Boehm, J., Boeing, H., Brenner, H., Brezina, S., Buch, S., Buchanan, D. D., Burnett-Hartman, A., Butterbach, K., Caan, B. J., Campbell, P. T., Carlson, C. S., Castellví-Bel, S., Chan, A. T., Chang-Claude, J., Chanock, S. J., Chirlaque, M-D., Cho, S. H., Connolly, C. M., Cross, A. J., Cuk, K., Curtis, K. R., de la Chapelle, A., Doheny, K. F., Duggan, D., Easton, D. F., Elias, S. G., Elliott, F., English, D. R., Feskens, E. J. M., Figueiredo, J. C., Fischer, R., FitzGerald, L. M., Forman, D., Gala, M., Gallinger, S., Gauderman, W. J., Giles, G. G., Gillanders, E., Gong, J., Goodman, P. J., Grady, W. M., Grove, J. S., Gsur, A., Gunter, M. J., Haile, R. W., Hampe, J., Hampel, H., Harlid, S., Hayes, R. B., Hofer, P., Hoffmeister, M., Hopper, J. L., Hsu, W-L., Huang, W-Y., Hudson, T. J., Hunter, D. J., Ibañez-Sanz, G., Idos, G. E., Ingersoll, R., Jackson, R. D., Jacobs, E. J., Jenkins, M. A., Joshi, A. D., Joshu, C. E., Keku, T. O., Key, T. J., Kim, H. R., Kobayashi, E., Kolonel, L. N., Kooperberg, C., Kühn, T., Küry, S., Kweon, S-S., Larsson, S. C., Laurie, C. A., Le Marchand, L., Leal, S. M., Lee, S. C., Lejbkowicz, F., Lemire, M., Li, C. I., Li, L., Lieb, W., Lin, Y., Lindblom, A., Lindor, N. M., Ling, H., Louie, T. L., Männistö, S., Markowitz, S. D., Martín, V., Masala, G., McNeil, C. E., Melas, M., Milne, R. L., Moreno, L., Murphy, N., Myte, R., Naccarati, A., Newcomb, P. A., Offit, K., Ogino, S., Onland-Moret, N. C., Pardini, B., Parfrey, P. S., Pearlman, R., Perduca, V., Pharoah, P. D. P., Pinchev, M., Platz, E. A., Prentice, R. L., Pugh, E., Raskin, L., Rennert, G., Rennert, H. S., Riboli, E., Rodríguez-Barranco, M., Romm, J., Sakoda, L. C., Schafmayer, C., Schoen, R. E., Seminara, D., Shah, M., Shelford, T., Shin, M-H., Shulman, K., Sieri, S., Slattery, M. L., Southey, M. C., Stadler, Z. K., Stegmaier, C., Su, Y-R., Tangen, C. M., Thibodeau, S. N., Thomas, D. C., Thomas, S. S., Toland, A. E., Trichopoulou, A., Ulrich, C. M., Van Den Berg, D. J., van Duijnhoven, F. J. B., Van Guelpen, B., van Kranen, H., Vijai, J., Visvanathan, K., Vodicka, P., Vodickova, L., Vymetalkova, V., Weigl, K., Weinstein, S. J., White, E., Win, A. K., Wolf, C. R., Wolk, A., Woods, M. O., Wu, A. H., Zaidi, S. H., Zanke, B. W., Zhang, Q., Zheng, W., Scacheri, P. C., Potter, J. D., Bassik, M. C., Kundaje, A., Casey, G., Moreno, V., Abecasis, G. R., Nickerson, D. A., Gruber, S. B., Hsu, L. & Peters, U., 1 Jan 2019, In: Nature Genetics. 51, 1, p. 76-87 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  136 Citations (Scopus)

  238 Downloads (Pure)

• Discovery of indoline-2-carboxamide derivatives as a new class of brain-penetrant inhibitors of Trypanosoma brucei

  Cleghorn, L. A. T., Albrecht, S., Stojanovski, L., Simeons, F. R. J., Norval, S., Kime, R., Collie, I. T., De Rycker, M., Campbell, L., Hallyburton, I., Frearson, J. A., Wyatt, P. G., Read, K. D. & Gilbert, I. H., 8 Oct 2015, In: Journal of Medicinal Chemistry. 58, 19, p. 7695-7706 12 p.

  Research output: Contribution to journal › Article › peer-review
  23 Citations (Scopus)

• Discovery of inhibitors of Trypanosoma brucei by phenotypic screening of a focused protein kinase library

  Woodland, A., Thompson, S., Cleghorn, L. A. T., Norcross, N., De Rycker, M., Grimaldi, R., Hallyburton, I., Rao, B., Norval, S., Stojanovski, L., Brun, R., Kaiser, M., Frearson, J. A., Gray, D. W., Wyatt, P. G., Read, K. D. & Gilbert, I. H., Nov 2015, In: ChemMedChem. 10, 11, p. 1809-1820 12 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• Discovery of invariants through automated theory formation

  Llano, M. T., Ireland, A. & Pease, A., Oct 2012, In: Formal Aspects of Computing. n/a, p. 1-47 47 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Discovery of New Bromodomain Scaffolds by Biosensor Fragment Screening

  Navratilova, I., Aristotelous, T., Picaud, S., Chaikuad, A., Knapp, S., Filappakopoulos, P. & Hopkins, A. L., 8 Dec 2016, In: ACS Medicinal Chemistry Letters. 7, 12, p. 1213-1218 6 p.

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  11 Citations (Scopus)

• Discovery of NMS-E973 as novel, selective and potent inhibitor of heat shock protein 90 (Hsp90)

  Brasca, M. G., Mantegani, S., Amboldi, N., Bindi, S., Caronni, D., Casale, E., Ceccarelli, W., Colombo, N., De Ponti, A., Donati, D., Ermoli, A., Fachin, G., Felder, E. R., Ferguson, R. D., Fiorelli, C., Guanci, M., Isacchi, A., Pesenti, E., Polucci, P., Riceputi, L. & 4 others, Sola, F., Visco, C., Zuccotto, F. & Fogliatto, G., 15 Nov 2013, In: Bioorganic & Medicinal Chemistry. 21, 22, p. 7047-7063 17 p.

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  18 Citations (Scopus)

• Discovery of non-steroidal mifepristone mimetics: pyrazoline-based PR antagonists

  Jones, D. G., Liang, X., Stewart, E. L., Noe, R. A., Kallander, L. S., Madauss, K. P., Williams, S. P., Thompson, S. K., Gray, D. W. & Hoekstra, W. J., 2005, In: Bioorganic & Medicinal Chemistry Letters. 15, 13, p. 3203-6 4 p.

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  28 Citations (Scopus)

• Discovery of novel heart rate-associated loci using the Exome Chip

  van den Berg, M. E., Warren, H. R., Cabrera, C. P., Verweij, N., Mifsud, B., Haessler, J., Bihlmeyer, N. A., Fu, Y-P., Weiss, S., Lin, H. J., Grarup, N., Li-Gao, R., Pistis, G., Shah, N., Brody, J. A., Müller-Nurasyid, M., Lin, H., Mei, H., Smith, A. V., Lyytikäinen, L-P. & 101 others, Hall, L. M., van Setten, J., Trompet, S., Prins, B. P., Isaacs, A., Radmanesh, F., Marten, J., Entwistle, A., Kors, J. A., Silva, C. T., Alonso, A., Bis, J. C., de Boer, R. A., de Haan, H. G., de Mutsert, R., Dedoussis, G., Dominiczak, A. F., Doney, A. S. F., Ellinor, P. T., Eppinga, R. N., Felix, S. B., Guo, X., Hagemeijer, Y., Hansen, T., Harris, T. B., Heckbert, S. R., Huang, P. L., Hwang, S-J., Kähönen, M., Kanters, J. K., Kolcic, I., Launer, L. J., Li, M., Yao, J., Linneberg, A., Liu, S., Macfarlane, P. W., Mangino, M., Morris, A. D., Mulas, A., Murray, A. D., Nelson, C. P., Orrú, M., Padmanabhan, S., Peters, A., Porteous, D. J., Poulter, N. R., Psaty, B. M., Qi, L., Raitakari, O. T., Rivadeneira, F., Roselli, C., Rudan, I., Sattar, N., Sever, P., Sinner, M. F., Soliman, E. Z., Spector, T. D., Stanton, A. V., Stirrups, K. E., Taylor, K. D., Tobin, M. D., Uitterlinden, A. G., Vaartjes, I., Hoes, A. W., van der Meer, P., Völker, U., Waldenberger, M., Xie, Z., Zoledziewska, M., Tinker, A., Polasek, O., Rosand, J., Jamshidi, Y., van Duijn, C. M., Zeggini, E., Wouter Jukema, J., Asselbergs, F. W., Samani, N. J., Lehtimäki, T., Gudnason, V., Wilson, J., Lubitz, S. A., Kääb, S., Sotoodehnia, N., Caulfield, M. J., Palmer, C. N. A., Sanna, S., Mook-Kanamori, D. O., Deloukas, P., Pedersen, O., Rotter, J. I., Dörr, M., O'Donnell, C. J., Hayward, C., Arking, D. E., Kooperberg, C., van der Harst, P., Eijgelsheim, M., Stricker, B. H. C. & Munroe, P. B., 15 Jun 2017, In: Human Molecular Genetics. 26, 12, p. 2346-2363 18 p.

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  15 Citations (Scopus)

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• Discovery of N-Phenyl-4-(thiazol-5-yl)pyrimidin-2-amine aurora kinase inhibitors

  Wang, S., Midgley, C. A., Scaërou, F., Grabarek, J. B., Griffiths, G., Jackson, W., Kontopidis, G., McClue, S. J., McInnes, C., Meades, C., Mezna, M., Plater, A., Stuart, I., Thomas, M. P., Wood, G., Clarke, R. G., Blake, D. G., Zheleva, D. I., Lane, D. P., Jackson, R. C. & 2 others, Glover, D. M. & Fischer, P. M., 10 Jun 2010, In: Journal of Medicinal Chemistry. 53, 11, p. 4367-4378 12 p.

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  79 Citations (Scopus)

• Discovery of potent and selective 5-azaindazole inhibitors of leucine-rich repeat kinase 2 (LRRK2) - Part 1

  Osborne, J., Birchall, K., Tsagris, D. J., Lewis, S. J., Smiljanic-Hurley, E., Taylor, D. L., Levy, A., Alessi, D. & McIver, E. G., 15 Feb 2019, In: Bioorganic & Medicinal Chemistry Letters. 29, 4, p. 668-673 6 p.

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• Discovery of potent and selective covalent inhibitors of JNK

  Zhang, T., Inesta-Vaquera, F., Niepel, M., Zhang, J., Ficarro, S. B., Machleidt, T., Xie, T., Marto, J. A., Kim, N., Sim, T., Laughlin, J. D., Park, H., LoGrasso, P. V., Patricelli, M., Nomanbhoy, T. K., Sorger, P. K., Alessi, D. R. & Gray, N. S., 27 Jan 2012, In: Chemistry & Biology. 19, 1, p. 140-154 15 p.

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  210 Citations (Scopus)