Find Research outputs

Search results

• Article

  Keap1, the sensor for electrophiles and oxidants that regulates the phase 2 response, is a zinc metalloprotein

  Dinkova-Kostova, A. T., Holtzclaw, W. D. & Wakabayashi, N., 10 May 2005, In: Biochemistry. 44, 18, p. 6889-6899 11 p.

  Research output: Contribution to journal › Article › peer-review
  173 Citations (Scopus)

• Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression

  McMahon, M., Itoh, K., Yamamoto, M. & Hayes, J. D., 13 Jun 2003, In: Journal of Biological Chemistry. 278, 24, p. 21592-21600 9 p.

  Research output: Contribution to journal › Article › peer-review
  838 Citations (Scopus)

• KEAP₁ inhibition is neuroprotective and suppresses the development of epilepsy

  Shekh-Ahmad, T., Eckel, R., Dayalan Naidu, S., Higgins, M., Yamamoto, M., Dinkova-Kostova, A., Kovac, S., Abramov, A. Y. & Walker, M. C., May 2018, In: Brain. 141, 5, p. 1390-1403 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  55 Citations (Scopus)

  214 Downloads (Pure)

• KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients

  Quinti, L., Dayalan Naidu, S., Träge, U., Chen, X., Kegel-Gleason, K., Lleres, D., Connolly, C., Chopra, V., Low, C., Moniot, S., Sapp, E., Tousley, A. R., Vodicka, P., Van Kanegan, M. J., Kaltenbach, L. S., Crawford, L. A., Fuszard, M., Higgins, M., Miller, J. R. C., Farmer, R. E. & 19 others, Potluri, V., Samajdar, S., Meisel, L., Zhang, N., Snyder, A., Stein, R., Hersch, S. M., Ellerby, L. M., Weerapana, E., Schwarzschild, M. A., Steegborn, C., Leavitt, B. R., Degterev, A., Tabrizi, S. J., Lo, D. C., DiFiglia, M., Thompson, L. M., Dinkova-Kostova, A. & Kazantsev, A. G., 6 Jun 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 23, p. e4676-e4685 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  62 Citations (Scopus)

  168 Downloads (Pure)

• Keap1 perceives stress via three sensors for the endogenous signaling molecules nitric oxide, zinc, and alkenals

  McMahon, M., Lamont, D. J., Beattie, K. A. & Hayes, J. D., 2 Nov 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 44, p. 18838-18843 6 p.

  Research output: Contribution to journal › Article › peer-review
  303 Citations (Scopus)

• Keep, lose, change: prompts for the re-design of product concepts in a focus group setting

  Frohlich, D. M., Lim, C. S. C. & Ahmed, A., 2014, In: CoDesign. 10, 2, p. 80-95 16 p.

  Research output: Contribution to journal › Article › peer-review
  14 Citations (Scopus)

• Keeping or destroying records some current issues in retention

  Brown, C., May 1999, In: Business Archives. 77, p. 31-44 14 p.

  Research output: Contribution to journal › Article

• Keeping up appearances: Police Rhetoric, Public Trust and "Police Scandal" in London and Berlin, 1880-1914

  Johansen, A., 2011, In: Crime, History & Societies. 15, 1, p. 59-83 25 p.

  Research output: Contribution to journal › Article › peer-review

• Keeping Up Textual Appearances: The Road Vehicles (Display of Registration Marks) Regulations 2001

  Giddens, T., 18 Mar 2020, (E-pub ahead of print) In: Law, Technology and Humans. 2, 1, p. 1-16 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  42 Downloads (Pure)

• Keller's arthroplasty in adults with hallux valgus and hallux rigidus

  Putti, A. B., Pande, S., Adam, R. F. & Abboud, R. J., 1 Mar 2012, In: Foot and Ankle Surgery. 18, 1, p. 34-38 5 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Kelly v Kelly and the Royal Infirmary of Edinburgh NHS Trust

  Ferguson, P. R., Dec 1997, In: Family Law. 27, p. 788-790 3 p.

  Research output: Contribution to journal › Article

• Kelp (Laminaria digitata) increases germination and affects rooting and plant vigour in crops and native plants from an arable grassland in the Outer Hebrides, Scotland

  Thorsen, M. K., Woodward, S. & McKenzie, B. M., Sep 2010, In: Journal of Coastal Conservation. 14, 3, p. 239-247 9 p.

  Research output: Contribution to journal › Article › peer-review
  15 Citations (Scopus)

• Kelvin-Helmholtz instability in a current-vortex sheet at a 3D magnetic null

  Wyper, P. F. & Pontin, D. I., Mar 2013, In: Physics of Plasmas. 20, 3, 032117.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• Kenneth Buthlay (1926-2009)

  Riach, A., Robb, D. & McCulloch, M. P., 2010, In: Scottish Literary Review. 2, 2, p. XIII-XVI 4 p.

  Research output: Contribution to journal › Article › peer-review

• Keratin 12 missense mutation induces the unfolded protein response and apoptosis in meesmann epithelial corneal dystrophy

  Allen, E. H. A., Courtney, D. G., Atkinson, S. D., Moore, J. E., Mairs, L., Poulsen, E. T., Schiroli, D., Maurizi, E., Cole, C., Hickerson, R. P., James, J., Murgatroyd, H., Smith, F. J. D., MacEwen, C., Enghild, J. J., Nesbit, M. A., Leslie Pedrioli, D. M., McLean, W. H. I. & Moore, C. B. T., 15 Mar 2016, In: Human Molecular Genetics. 25, 6, p. 1176-1191 16 p., ddw001.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  9 Citations (Scopus)

  142 Downloads (Pure)

• Keratin 14-Null Cells as a Model to Test the Efficacy of Gene Therapy Approaches in Epithelial Cells

  D'Alessandro, M., Coats, S. E., Jonkmann, M. F., Leigh, I. M. & Lane, B., Jul 2011, In: Journal of Investigative Dermatology. 131, 7, p. 1412-1419 8 p.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• Keratin 16 and keratin 17 mutations cause pachyonychia congenita

  McLean, W. H. I., Rugg, E. L., Lunny, D. P., Morley, S. M., Lane, E. B., Swensson, O., Dopping-Hepenstal, P. J. C., Griffiths, W. A. D., Eady, R. A. J., Higgins, C., Navsaria, H. A., Leigh, I. M., Strachan, T., Kunkeler, L. & Munro, C. S., Mar 1995, In: Nature Genetics. 9, 3, p. 273-278 6 p.

  Research output: Contribution to journal › Article › peer-review
  286 Citations (Scopus)

• Keratin 17 mutations in four families from India with pachyonychia congenita

  Agarwala, M., Salphale, P., Peter, D., Wilson, N. J., Pulimood, S., Schwartz, M. E. & Smith, F. J. D., 10 Jul 2017, In: Indian Journal of Dermatology. 62, 4, p. 422-426 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  4 Citations (Scopus)

• Keratin 7 promoter selectively targets transgene expression to normal and neoplastic pancreatic ductal cells in vitro and in vivo

  Pujal, J., Huch, M., Jose, A., Abasolo, I., Rodolosse, A., Duch, A., Sanchez-Palazon, L., Smith, F. J. D., McLean, W. H. I., Fillat, C. & Real, F. X., May 2009, In: FASEB Journal. 23, 5, p. 1366-1375 10 p.

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)

• Keratin 9 Is Required for the Structural Integrity and Terminal Differentiation of the Palmoplantar Epidermis

  Fu, D. J., Thomson, C., Lunny, D. P., Dopping-Hepenstal, P. J., McGrath, J. A., Smith, F. J. D., McLean, W. H. I. & Leslie Pedrioli, D. M., 2013, In: Journal of Investigative Dermatology. n/a, n/a.

  Research output: Contribution to journal › Article › peer-review
  52 Citations (Scopus)

• Keratin antigen retrieval in oral mucosal biopsies using microwave processing

  Ogden, G. R., Lunny, D. & Lane, E. B., 1 Jan 1996, In: Histochemical Journal. 28, 12, p. 875-882 8 p.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• Keratin K6c mutations cause focal palmoplantar keratoderma

  Wilson, N. J., Messenger, A. G., Leachman, S. A., O'Toole, E. A., Lane, E. B., McLean, W. H. I. & Smith, F. J. D., Feb 2010, In: Journal of Investigative Dermatology. 130, 2, p. 425-429 5 p.

  Research output: Contribution to journal › Article › peer-review
  40 Citations (Scopus)

• Keratin mutations of epidermolysis bullosa simplex alter the kinetics of stress response to osmotic shock

  D'Alessandro, M., Russell, D., Morley, S. M., Davies, A. M. & Lane, E. B., 2002, In: Journal of Cell Science. 115, 22, p. 4341-4351 11 p.

  Research output: Contribution to journal › Article › peer-review
  89 Citations (Scopus)

• Keratin profiles of normal and malignant oral mucosa using exfoliative cytology

  Ogden, G. R., McQueen, S., Chisholm, D. M. & Lane, E. B., 1993, In: Journal of Clinical Pathology. 46, 4, p. 352-356 5 p.

  Research output: Contribution to journal › Article › peer-review

  26 Citations (Scopus)

• Keratins and skin disease

  Knöbel, M., O’Toole, E. A. & Smith, F. J. D., Jun 2015, In: Cell and Tissue Research. 360, 3, p. 583-589 7 p.

  Research output: Contribution to journal › Article › peer-review
  51 Citations (Scopus)

• Ketamine and ditran block end-plate ion conductance and [³H]phencyclidine binding to electric organ membrane

  Volle, R. L., Alkadhi, K. A., Branisteanu, D. D., Reynolds, L. S., Epstein, P. M., Smilowitz, H., Lambert, J. J. & Henderson, E. G., Jun 1982, In: Journal of Pharmacology and Experimental Therapeutics. 221, 3, p. 570-576 7 p.

  Research output: Contribution to journal › Article › peer-review
  17 Citations (Scopus)

• Ketamine as the anaesthetic for electroconvulsive therapy: the KANECT randomised controlled trial

  Fernie, G., Currie, J., Perrin, J. S., Stewart, C. A., Anderson, V., Bennett, D. M., Hay, S. & Reid, I. C., 1 Jun 2017, In: British Journal of Psychiatry. 210, 6, p. 422-428 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  29 Citations (Scopus)

  278 Downloads (Pure)

• Ketamine inhibits synaptic transmission and nicotinic acetylcholine receptor-mediated responses in rat intracardiac ganglia in situ

  Harper, A. A., Rimmer, K., Dyavanapalli, J., McArthur, J. R. & Adams, D. J., 15 Mar 2020, In: Neuropharmacology. 165, 8 p., 107932.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  140 Downloads (Pure)

• Ketamine potentiates 5‐HT₃ receptor‐mediated currents in rabbit nodose ganglion neurones

  Peters, J. A., Malone, H. M. & Lambert, J. J., Jul 1991, In: British Journal of Pharmacology. 103, 3, p. 1623-1625 3 p.

  Research output: Contribution to journal › Article › peer-review
  26 Citations (Scopus)

• Ketamine pre-treatment dissociates the effects of electroconvulsive stimulation on mossy fibre sprouting and cellular proliferation in the dentate gyrus

  Lamont, S. R., Stanwell, B. J., Hill, R., Reid, I. C. & Stewart, C. A., 2005, In: Brain Research. 1053, 1-2, p. 27-32 6 p.

  Research output: Contribution to journal › Article › peer-review
  22 Citations (Scopus)

• Ketamine prevents ECS-induced synaptic enhancement in rat hippocampus

  Stewart, C. A. & Reid, I. C., 29 Aug 1994, In: Neuroscience Letters. 178, 1, p. 11-14 4 p.

  Research output: Contribution to journal › Article › peer-review
  45 Citations (Scopus)

• Ketoacidosis with pulmonary embolism: a formula to detect clots?

  Kidder, D., Pearson, E., Davidson, J., Swaminathan, K. & Petrie, J. R., 1 Nov 2008, In: British Journal of Diabetes and Vascular Disease. 8, 6, p. 301 1 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Key challenges and ways forward in researching the "good death": qualitative in-depth interview and focus group study

  Kendall, M., Harris, F., Boyd, K., Sheikh, A., Murray, S. A., Brown, D., Mallinson, I., Kearney, N. & Worth, A., 2007, In: BMJ. 334, 7592, p. 1-6 6 p.

  Research output: Contribution to journal › Article › peer-review
  85 Citations (Scopus)

• Key differences identified between actinic keratosis and cutaneous squamous cell carcinoma by transcriptome profiling

  Lambert, S. R., Mladkova, N., Gulati, A., Hamoudi, R., Purdie, K., Cerio, R., Leigh, I., Proby, C. & Harwood, C. A., 21 Jan 2013, In: British Journal of Cancer. 110, 2, p. 520-529 10 p.

  Research output: Contribution to journal › Article › peer-review
  64 Citations (Scopus)

• Keyholders and flak jackets: the method in the madness of mixed metaphors

  Maclean, A., Sep 2008, In: Clinical Ethics. 3, 3, p. 121-126 6 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Keynesianism Constrained

  Tomlinson, J., 2009, In: Radical Philosophy. 155, p. 6-10 5 p.

  Research output: Contribution to journal › Article › peer-review

• Key parameters of face shape variation in 3D in a large sample

  Evison, M., Dryden, I., Fieller, N., Mallett, X., Morecroft, L., Schofield, D. & Bruegge, R. V., Jan 2010, In: Journal of Forensic Sciences. 55, 1, p. 159-162 4 p.

  Research output: Contribution to journal › Article › peer-review
  26 Citations (Scopus)

• Key performance indicators (KPIs) and priority setting in using the multi-attribute approach for assessing sustainable intelligent buildings

  ALwaer, H. & Clements-Croome, D. J., Apr 2010, In: Building and Environment. 45, 4, p. 799-807 9 p.

  Research output: Contribution to journal › Article › peer-review
  210 Citations (Scopus)

• Key role for AMP-activated protein kinase in the ventromedial hypothalamus in regulating counterregulatory hormone responses to acute hypoglycemia

  McCrimmon, R. J., Shaw, M., Fan, X., Cheng, H., Ding, Y., Vella, M. C., Zhou, L., Mcnay, E. C. & Sherwin, R. S., Feb 2008, In: Diabetes. 57, 2, p. 444-450 7 p.

  Research output: Contribution to journal › Article › peer-review
  127 Citations (Scopus)

• Keystroke dynamics in the pre-touchscreen era

  Ahmad, N., Szymkowiak, A. & Campbell, P. A., 19 Dec 2013, In: Frontiers in Human Neuroscience. 7, 835.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24

  Birnbaum, S., Ludwig, K. U., Reutter, H., Herms, S., Steffens, M., Rubini, M., Baluardo, C., Ferrian, M., de Assis, N. A., Alblas, M. A., Barth, S., Freudenberg, J., Lauster, C., Schmidt, G., Scheer, M., Braumann, B., Berge, S. J., Reich, R. H., Schiefke, F., Hemprich, A. & 14 others, Poetzsch, S., Steegers-Theunissen, R. P., Poetzsch, B., Moebus, S., Horsthemke, B., Kramer, F-J., Wienker, T. F., Mossey, P. A., Propping, P., Cichon, S., Hoffmann, P., Knapp, M., Noethen, M. M. & Mangold, E., Apr 2009, In: Nature Genetics. 41, 4, p. 473-477 5 p.

  Research output: Contribution to journal › Article › peer-review
  330 Citations (Scopus)

• Kidney biopsy findings in primary Sjogren syndrome

  Kidder, D., Rutherford, E., Kipgen, D., Fleming, S., Geddes, C. & Stewart, G. A., 2015, In: Nephrology Dialysis Transplantation. 7 p.

  Research output: Contribution to journal › Article › peer-review
  35 Citations (Scopus)

• Kikuchi's disease displaying a t(2:16) chromosomal translocation

  Robertson, K. E., Forsyth, P. D., Batstone, P. J., Levison, D. A. & Goodlad, J. R., Apr 2007, In: Journal of Clinical Pathology. 60, 4, p. 433-435 3 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Killing with proficiency: integrated post-translational regulation of an offensive Type VI secretion system

  Ostrowski, A., Cianfanelli, F. R., Porter, M., Mariano, G., Peltier, J., Wong, J. J., Swedlow, J. R., Trost, M. & Coulthurst, S. J., 27 Jul 2018, In: PLoS Pathogens. 14, 7, p. 1-25 25 p., e1007230.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  13 Citations (Scopus)

  154 Downloads (Pure)

• Killing “without getting into trouble”? Assisted suicide and Scots criminal law

  Ferguson, P. R., Sep 1998, In: Edinburgh Law Review. 2, 3, p. 288-314 27 p.

  Research output: Contribution to journal › Article › peer-review

• Kinase and channel activity of TRPM6 are co-ordinated by a dimerization motif and pocket interaction

  van der Wijst, J., Blanchard, M. G., Woodroof, H. I., Macartney, T. J., Gourlay, R., Hoenderop, J. G., Bindels, R. J. & Alessi, D. R., 13 May 2014, In: Biochemical Journal. 460, 2, p. 165-175 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  9 Citations (Scopus)

  134 Downloads (Pure)

• Kinase drug discovery: What's next in the field?

  Cohen, P. & Alessi, D. R., 2013, In: ACS Chemical Biology. 8, 1, p. 96-104 9 p.

  Research output: Contribution to journal › Article › peer-review
  295 Citations (Scopus)

• Kinase inhibitors arrest neurodegeneration in cell and C. elegans models of LRRK2 toxicity

  Yao, C., Johnson, W. M., Gao, Y., Wang, W., Zhang, J., Deak, M., Alessi, D. R., Zhu, X., Mieyal, J. J., Roder, H., Wilson-Delfosse, A. L. & Chen, S. G., 15 Jan 2013, In: Human Molecular Genetics. 22, 2, p. 328-344 17 p.

  Research output: Contribution to journal › Article › peer-review
  59 Citations (Scopus)

• Kindlin-3 in the immune system

  Fagerholm, S. C., Lek, H. S. & Morrison, V. L., 2014, In: American Journal of Clinical and Experimental Immunology. 3, 1, p. 37-42 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  32 Downloads (Pure)

• Kindling the Singing Flame: The Burning of the Public Record Office (30 June 1922) as a Historical Problem

  Regan, J., 2015, In: Journal of the Old Athlone Society . 3, 10, p. 11-30 20 p.

  Research output: Contribution to journal › Article