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  • 2020
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  • 2016

Author

  • Victoria Cowling
Article

CAPAM: the mRNA cap adenosine N6 methyltransferase

Cowling, V., 1 Mar 2019, In : Trends in Biochemical Sciences. 44, 3, p. 183-185 3 p., 1545.

Research output: Contribution to journalArticle

Open Access
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5 Citations (Scopus)
112 Downloads (Pure)

CAP-MAP: cap analysis protocol with minimal analyte processing, a rapid and sensitive approach to analysing mRNA cap structures

Galloway, A., Atrih, A., Grzela, R., Darzynkiewicz, E., Ferguson, M. A. J. & Cowling, V. H., 26 Feb 2020, In : Open Biology. 10, 2, p. 1-13 13 p., 190306.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
47 Downloads (Pure)

CDK1-Cyclin B1 Activates RNMT, Coordinating mRNA Cap Methylation with G1 Phase Transcription

Aregger, M., Kaskar, A., Varshney, D., Fernandez-Sanchez, M. E., Inesta-Vaquera, F. A., Weidlich, S. & Cowling, V. H., 3 Mar 2016, In : Molecular Cell. 61, 5, p. 734-746 13 p.

Research output: Contribution to journalArticle

Open Access
File
20 Citations (Scopus)
156 Downloads (Pure)

c-Myc deregulation induces mRNA capping enzyme dependency

Lombardi, O., Varshney, D., Phillips, N. M. & Cowling, V. H., 16 Oct 2016, In : Oncotarget. 7, 50, p. 82273-82288 16 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
167 Downloads (Pure)

DHX15 regulates CMTR1-dependent gene expression and cell proliferation

Inesta-Vaquera, F., Chaugule, V. K., Galloway, A., Chandler, L., Rojas-Fernandez, A., Weidlich, S., Peggie, M. & Cowling, V., 18 Jun 2018, In : Life Science Alliance. 1, 3, 18 p., e201800092.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
160 Downloads (Pure)

Direct High-Throughput Screening Assay for mRNA Cap Guanine-N7 Methyltransferase Activity

Kasprzyk, R., Fido, M., Mamot, A., Wanat, P., Smietanski, M., Kopcial, M., Cowling, V. H., Kowalska, J. & Jemielity, J., 7 Apr 2020, In : Chemistry: a European Journal. 11 p.

Research output: Contribution to journalArticle

Human IFIT1 inhibits mRNA translation of rubulaviruses but not other members of the Paramyxoviridae family

Young, D. F., Andrejeva, J., Li, X., Inesta-Vaquera, F., Dong, C., Cowling, V. H., Goodbourn, S. & Randall, R. E., 15 Oct 2016, In : Journal of Virology. 90, 20, p. 9446-9456 11 p.

Research output: Contribution to journalArticle

Open Access
File
17 Citations (Scopus)
158 Downloads (Pure)

Mechanism of allosteric activation of human mRNA cap methyltransferase (RNMT) by RAM: Insights from accelerated molecular dynamics simulations

Bueren-Calabuig, J., Bage, M., Cowling, V. & Pisliakov, A., 19 Sep 2019, In : Nucleic Acids Research. 47, 16, p. 8675-8692 18 p., gkz613.

Research output: Contribution to journalArticle

Open Access
File
83 Downloads (Pure)

Molecular basis of RNA guanine-7 methyltransferase (RNMT) activation by RAM

Varshney, D., Petit, A-P., Bueren-Calabuig, J. A., Jansen, C., Fletcher, D. A., Peggie, M., Weidlich, S., Scullion, P., Pisliakov, A. V. & Cowling, V. H., 1 Dec 2016, In : Nucleic Acids Research. 44, 21, p. 10423-10436 14 p.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
375 Downloads (Pure)

mRNA Cap methylation in pluripotency and differentiation

Grasso, L., Suska, O., Davidson, L., Gonatopoulos-Pournatzis, T., Williamson, R., Wasmus, L., Wiedlich, S., Peggie, M., Stavridis, M. P. & Cowling, V. H., 2 Aug 2016, In : Cell Reports. 16, 5, p. 1352-1365 14 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
240 Downloads (Pure)

mRNA cap methyltransferase, RNMT-RAM, promotes RNA pol II-dependent transcription

Varshney, D., Lombardi, O., Schweikert, G., Dunn, S., Suska, O. & Cowling, V., May 2018, In : Cell Reports. 23, 5, p. 1530-1542 13 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
172 Downloads (Pure)

Oncogenic PIK3CA mutations increase dependency on the mRNA cap methyltransferase, RNMT, in breast cancer cells

Dunn, S., Lombardi, O., Lukoszek, R. & Cowling, V., Apr 2019, In : Open Biology. 9, 4, p. 1-15 15 p., 190052.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
113 Downloads (Pure)

Positioning Europe for the EPITRANSCRIPTOMICS challenge

Jantsch, M., Quattrone, A., O'Connell, M., Helm, M., Frye, M., Macias-Gonzales, M., Ohman, M., Ameres, S., Willems, L., Fuks, F., Oulas, A., Vanacova, S., Nielsen, H., Bousquet-Antonelli, C., Motorin, Y., Roignant, J-Y., Balatsos, N., Dinnyes, A., Baranov, P., Kelly, V. & 40 others, Lamm, A., Rechavi, G., Pelizzola, M., Liepins, J., Holodnuka Kholodnyuk, I., Zammit, V., Ayers, D., Drablos, F., Dahl, J. A., Bujnicki, J., Jeronimo, C., Almeida, R., Neagu, M., Costache, M., Bankovic, J., Banovic, B., Kyselovic, J., Valor, L. M., Selbert, S., Pir, P., Demircan, T., Cowling, V., Schäfer, M., Rossmanith, W., Lafontaine, D., David, A., Carre, C., Lyko, F., Schaffrath, R., Schwartz, S., Verdel, A., Klungland, A., Purta, E., Timotijevic, G., Cardona, F., Davalos, A., Ballana, E., O Carroll, D., Ule, J. & Fray, R., 3 Jun 2018, In : RNA Biology. 15, 6, p. 829-831 8 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
164 Downloads (Pure)

The eukaryotic translation initiation factor eIF4E elevates steady-state m7G capping of coding and noncoding transcripts

Culjkovic-Kraljacic, B., Skrabanek, L., Revuelta, M. V., Gasiorek, J., Cowling, V. H., Cerchietti, L. & Borden, K. L. B., 14 Oct 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 11 p.

Research output: Contribution to journalArticle

Open Access
File
1 Downloads (Pure)

The mRNA cap methyltransferase gene TbCMT1 is not essential in vitro but is a virulence factor in vivo for bloodstream form Trypanosoma brucei

Kelner, A., Tinti, M., Guther, M., Foth, B. J., Chappell, L., Berriman, M., Cowling, V. & Ferguson, M., 24 Jul 2018, In : PLoS ONE. 13, 7, p. 1-14 14 p., e0201263.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
129 Downloads (Pure)
Review article

mRNA cap regulation in mammalian cell function and fate

Galloway, A. & Cowling, V., Mar 2019, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1862, 3, p. 270-279 10 p.

Research output: Contribution to journalReview article

Open Access
File
14 Citations (Scopus)
86 Downloads (Pure)