Find Research Outputs

Search results

• Review article

  Mathematical models for immunology: current state of the art and future research directions

  Eftimie, R., Gillard, J. J. & Cantrell, D. A., Oct 2016, In: Bulletin of Mathematical Biology. 78, 10, p. 2091-2134 44 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Immunology
  • immunology
  • Allergy and Immunology
  • mathematical models
  • state of the art
  65 Citations (Scopus)

  186 Downloads (Pure)

• Quantitative Predictive Modelling Approaches to Understanding Rheumatoid Arthritis: A Brief Review

  Macfarlane, F. R., Chaplain, M. A. J. & Eftimie, R., Jan 2020, In: Cells. 9, 1, 26 p., 74.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Rheumatoid Arthritis
  • Disease Progression
  • Biological Models
  • Chronic Pain
  • Health Care Costs
  1 Citation (Scopus)

  63 Downloads (Pure)
• Editorial

  Preface

  Eftimie, R., 1 Jan 2018, In: Lecture Notes in Mathematics. 2232, p. vii-ix

  Research output: Contribution to journal › Editorial › peer-review
• Comment/debate

  Validation of multi-scale models for fibrosis. Comment on "Towards a unified approach in the modeling of fibrosis: A review with research perspectives" by M. Ben Amar and C. Bianca

  Eftimie, R., Jul 2016, In: Physics of Life Reviews. 17, p. 90-91 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  File
  2 Citations (Scopus)

  136 Downloads (Pure)
• Chapter

  Lyapunov-Schmidt and Centre Manifold reduction methods for nonlocal PDEs modelling animal aggregations

  Buono, P-L. & Eftimie, R., 2016, Mathematical sciences with multidisciplinary applications: in honor of Professor Christiane Rousseau. And in recognition of the Mathematics for Planet Earth Initiative. Toni, B. (ed.). Springer International Publishing, Vol. 157. p. 29-59 31 p. (Springer proceedings in mathematics & statistics; vol. 157).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Center Manifold Reduction
  • Hyperbolic Partial Differential Equations
  • Reduction Method
  • Animals
  • Aggregation
  4 Citations (Scopus)
• Book

  Hyperbolic and kinetic models for self-organised biological aggregations: A modelling and pattern formation approach

  Eftimie, R., 2018, 1 ed. Switzerland: Springer International Publishing. 288 p. (Lecture Notes in Mathematics; vol. 2232)

  Research output: Book/Report › Book

  • book
  • bacterium
  • ecological community
  • cell
  • kinetics
• Article

  Aggregation and travelling wave dynamics in a two-population model of cancer cell growth and invasion

  Bitsouni, V., Trucu, D., Chaplain, M. A. J. & Eftimie, R., Dec 2018, In: Mathematical Medicine and Biology: a Journal of the IMA. 35, 4, p. 541-577 37 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cell growth
  • Invasion
  • Cancer
  • Population Model
  • Traveling Wave
  8 Citations (Scopus)

  162 Downloads (Pure)

• A kinetic theory approach for modelling tumour and macrophages heterogeneity and plasticity during cancer progression

  Eftimie, R. & Gibelli, L., 4 May 2020, In: Mathematical Models and Methods in Applied Sciences. 30, 4, p. 659-683 25 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Macrophages
  • Macrophage
  • Kinetic theory
  • Kinetic Theory
  • Progression
  2 Citations (Scopus)

  39 Downloads (Pure)

• A mathematical model for the role of macrophages in the persistence and elimination of oncolytic viruses

  Almuallem, N. & Eftimie, R., 8 Apr 2020, In: Mathematics in Applied Sciences and Engineering. 1, 2, p. 100-123 24 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Oncolytic Viruses
  • Vesicular Stomatitis
  • Theoretical Models
  • Macrophages
  • Viruses
  23 Downloads (Pure)

• Bifurcations and chaotic dynamics in a tumour-immune-virus system

  Eftimie, R., Macnamara, C. K., Dushoff, J., Bramson, J. L. & Earn, D. J. D., 7 Dec 2016, In: Mathematical Modelling of Natural Phenomena. 11, 5, p. 65-85 21 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Chaotic Dynamics
  • Viruses
  • Virus
  • Tumor
  • Tumors
  9 Citations (Scopus)

  186 Downloads (Pure)

• Directionality of macrophages movement in tumour invasion: a multiscale moving boundary approach

  Suveges, S., Eftimie, R. & Trucu, D., Dec 2020, In: Bulletin of Mathematical Biology. 82, 12, 50 p., 148.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Macrophages
  • Macrophage
  • Invasion
  • Moving Boundary
  • Tumor
  16 Downloads (Pure)

• Improving cancer detection through combinations of cancer and immune biomarkers: a modelling approach

  Eftimie, R. & Hassanein, E., 20 Mar 2018, In: Journal of Translational Medicine. 16, 1, p. 1-16 16 p., 73.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Biomarkers
  • Tumor Biomarkers
  • Interleukin-7
  • Early Detection of Cancer
  • Neoplasms
  5 Citations (Scopus)

  190 Downloads (Pure)

• Investigation into the role of macrophages heterogeneity on solid tumour aggregations

  Eftimie, R., Apr 2020, In: Mathematical Biosciences. 322, 15 p., 108325.

  Research output: Contribution to journal › Article › peer-review

  • Macrophages
  • Macrophage
  • Tumor
  • Tumors
  • Aggregation

• Mathematical Modelling of Cancer Invasion: The Multiple Roles of TGF-β Pathway on Tumour Proliferation and Cell Adhesion

  Bitsouni, V., Chaplain, M. & Eftimie, R., 6 Jul 2017, In: Mathematical Models and Methods in Applied Sciences. 27, 10, p. 1929-1962 34 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cell Adhesion
  • Intercellular Signaling Peptides and Proteins
  • Cell adhesion
  • Growth Factors
  • Proliferation
  9 Citations (Scopus)

  184 Downloads (Pure)

• Model based analysis of the heterogeneity in the tumour size dynamics differentiates vemurafenib, dabrafenib and trametinib in metastatic melanoma

  Mistry, H. B., Orrell, D. & Eftimie, R., 1 Feb 2018, In: Cancer Chemotherapy and Pharmacology. 81, 2, p. 325-332 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • dabrafenib
  • Vemurafenib
  • Tumors
  • Melanoma
  • trametinib
  3 Citations (Scopus)

  194 Downloads (Pure)

• Modelling and investigation of the CD4⁺ T cells-macrophages paradox in melanoma immunotherapies

  Eftimie, R. & Hamam, H., 7 May 2017, In: Journal of Theoretical Biology. 420, p. 82-104 23 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Macrophages
  • Macrophage
  • Immunotherapy
  • T-cells
  • Melanoma
  11 Citations (Scopus)

  199 Downloads (Pure)

• Modelling the collective response of heterogeneous cell populations to stationary gradients and chemical signal relay

  Pineda, M. & Eftimie, R., 16 Nov 2017, In: Physical Biology. 14, 6, p. 1-14 14 p., 066003.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Population Dynamics
  • Biological Phenomena
  • Cell Aggregation
  • Behavior Control
  • Cell Separation
  1 Citation (Scopus)

  171 Downloads (Pure)

• Modelling the effects of environmental heterogeneity within the lung on the tuberculosis life-cycle

  Pitcher, M. J., Bowness, R., Dobson, S., Eftimie, R. & Gillespie, S. H., 7 Dec 2020, In: Journal of Theoretical Biology. 506, 18 p., 110381.

  Research output: Contribution to journal › Article › peer-review

  • Life Cycle
  • Tuberculosis
  • Lung
  • tuberculosis
  • Life Cycle Stages
  1 Citation (Scopus)

• Modelling the transmission of infectious diseases inside hospital bays: implications for COVID-19

  Moreno Martos, D., Parcell, B. J. & Eftimie, R., 2020, In: Mathematical Biosciences and Engineering. 17, 6, p. 8084-8104 21 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Bays
  • Severe Acute Respiratory Syndrome
  • Infectious Disease Transmission
  • Infectious Diseases
  • infectious diseases
  12 Downloads (Pure)

• Multiscale Moving Boundary Modelling of Cancer Interactions with a Fusogenic Oncolytic Virus: the Impact of Syncytia Dynamics

  Alzahrani, T., Eftimie, R. & Trucu, D., May 2020, In: Mathematical Biosciences. 323, p. 1-22 22 p., 108296.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Oncolytic Viruses
  • Moving Boundary
  • Viruses
  • giant cells
  • Virus
  1 Citation (Scopus)

  9 Downloads (Pure)

• Non-local multiscale approaches for tumour-oncolytic viruses interactions

  Alsisi, A., Eftimie, R. & Trucu, D., 30 Sep 2020, In: Mathematics in Applied Sciences and Engineering. 1, 3, p. 207-273 25 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • viruses
  • tumors
  • cancer
  • cells
  • interactions
  132 Downloads (Pure)

• Non-local parabolic and hyperbolic models for cell polarisation in heterogeneous cancer cell populations

  Bitsouni, V. & Eftimie, R., 1 Oct 2018, In: Bulletin of Mathematical Biology. 80, 10, p. 2600-2632 33 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cell Population
  • Polarization
  • Cancer
  • Cells
  • cancer
  2 Citations (Scopus)

  153 Downloads (Pure)

• Oncolytic viral therapies and the delicate balance between virus-macrophage-tumour interactions: a mathematical approach

  Almuallem, N., Trucu, D. & Eftimie, R., 7 Dec 2020, (Accepted/In press) In: Mathematical Biosciences and Engineering.

  Research output: Contribution to journal › Article › peer-review

  • Macrophages
  • Macrophage
  • Oncogenic Viruses
  • Viruses
  • Therapy

• Pattern formation in a nonlocal mathematical model for the multiple roles of the TGF-β pathway in tumour dynamics

  Eftimie, R., Perez, M. & Buono, P-L., Jul 2017, In: Mathematical Biosciences. 289, p. 96-115 20 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pattern Formation
  • Pathway
  • Cell adhesion
  • Tumor
  • Tumors
  5 Citations (Scopus)

  169 Downloads (Pure)

• The Evolution of Communication Mechanisms in Self-Organised Ecological Aggregations: Impact on Pattern Formation

  Eftimie, R., 28 Aug 2020, In: Mathematical Models and Methods in Applied Sciences.

  Research output: Contribution to journal › Article › peer-review

  • Pattern Formation
  • Aggregation
  • Communication
  • Agglomeration
  • Animals
  1 Citation (Scopus)

• The impact of environmental noise on animal communication: pattern formation in a class of deterministic and stochastic hyperbolic models for self-organised biological aggregations

  Eftimie, R., 10 Aug 2018, In: Biomath. 7, 1, p. 1-18 18 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Animal Communication
  • Biocommunications
  • Pattern Formation
  • Spatio-temporal Patterns
  • Animals
  195 Downloads (Pure)

• The re-polarisation of M2 and M1 macrophages and its role on cancer outcomes

  den Breems, N. Y. & Eftimie, R., 7 Feb 2016, In: Journal of Theoretical Biology. 390, p. 23-39 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Repolarization
  • Macrophages
  • Macrophage
  • Tumor
  • Tumors
  27 Citations (Scopus)

  202 Downloads (Pure)

• Tumour-associated macrophages and oncolytic virotherapies: a mathematical investigation into a complex dynamics

  Eftimie, R. & Eftimie, G., 6 Feb 2018, In: Letters in Biomathematics. 5, sup1, p. S6-S35

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Macrophages
  • Oncolytic Virotherapy
  • Macrophage
  • Complex Dynamics
  • Viruses
  10 Citations (Scopus)

  189 Downloads (Pure)