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2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization
Murugesan, D., Ray, P. C., Bayliss, T., Prosser, G. A., Harrison, J. R., Green, K., Soares De Melo, C., Feng, T. S., Street, L. J., Chibale, K., Warner, D. F., Mizrahi, V., Epemolu, O., Scullion, P., Ellis, L., Riley, J., Shishikura, Y., Ferguson, L., Osuna-Cabello, M., Read, K. D. & 10 others, , 8 Jun 2018, In: ACS Infectious Diseases. 4, 6, p. 954-969 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)188 Downloads (Pure) -
30-day mortality after systemic anticancer treatment for breast and lung cancer in England: a population-based, observational study
Wallington, M., Saxon, E. B., Bomb, M., Smittenaar, R., Wickenden, M., McPhail, S., Rashbass, J., Chao, D., Dewar, J., Talbot, D., Peake, M., Perren, T., Wilson, C. & Dodwell, D., Sep 2016, In: Lancet Oncology. 17, 9, p. 1203-1216 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile67 Citations (Scopus)251 Downloads (Pure) -
30-day mortality following trauma and orthopaedic surgery during the peak of the COVID-19 pandemic: a multicentre regional analysis of 484 patients
Karayiannis, P. N., Roberts, V., Cassidy, R., Mayne, A. I. W., McAuley, D., Milligan, D. J. & Diamond, O., 1 Jul 2020, In: Bone & Joint Open. 1, 7, p. 392-397 6 p.Research output: Contribution to journal › Article › peer-review
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3D deformation field in growing plant roots reveals both mechanical and biological responses to axial mechanical forces
Bizet, F., Bengough, A. G., Hummel, I., Bogeat-Triboulot, M-B. & Dupuy, L. X., Oct 2016, In: Journal of Experimental Botany. 67, 19, p. 5605-5614 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)165 Downloads (Pure) -
3D-FEA of stress levels and distributions for different bases under a Class I composite restoration
Wang, Y., Liao, Z., Liu, D., Liu, Z., McIntyre, G. T., Jian, F., Lv, W., Yang, J., Zhao, Z. & Lai, W., Feb 2011, In: American Journal of Dentistry. 24, 1, p. 3-7 5 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
3D liquefaction criteria for seabed considering the cohesion and friction of soil
Ye, J., 1 Aug 2012, In: Applied Ocean Research. 37, p. 111-119 9 p.Research output: Contribution to journal › Article › peer-review
25 Citations (Scopus) -
3D Metal printed heat sinks with longitudinally varying lattice structure sizes using direct metal laser sintering
Shamvedi, D., McCarthy, O. J., O’Donoghue, E., Danilenkoff, C., O’Leary, P. & Raghavendra, R., 2018, In: Virtual and Physical Prototyping. 13, 4, p. 301-310 10 p.Research output: Contribution to journal › Article › peer-review
21 Citations (Scopus) -
3D MRI Analysis of the Lower Legs of Treated Idiopathic Congenital Talipes Equinovarus (Clubfoot)
Duce, S. L., D'Alessandro, M., Du, Y., Jagpal, B., Gilbert, F. J., Crichton, L., Barker, S., Collinson, J. M. & Miedzybrodzka, Z., 30 Jan 2013, In: PLoS ONE. 8, 1, 10 p., e54100.Research output: Contribution to journal › Article › peer-review
Open Access13 Citations (Scopus) -
3D-printing 'Ocean Plastic' - Fostering childrens' engagement with sustainability
Vones, K., Allan, D., Lambert, I. & Vettese, S., Sep 2018, In: Materials Today Communications. 16, p. 56-59 4 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
3D RNA-seq: A powerful and flexible tool for rapid and accurate differential expression and alternative splicing analysis of RNA-seq data for biologists
Guo, W., Tzioutziou, N., Stephen, G., Milne, I., Calixto, C., Waugh, R., Brown, J. W. S. & Zhang, R., 19 Dec 2020, In: RNA Biology. 14 p.Research output: Contribution to journal › Article › peer-review
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3D Technology Development and Dental Education: What Topics Are Best Suited for 3D Learning Resources?
Poblete, P., McAleer, S. & Mason, A. G., 1 Sep 2020, In: Dentistry Journal. 8, 3, 13 p., 95.Research output: Contribution to journal › Article › peer-review
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3-Fluoro-4-hydroxyprolines: Synthesis, conformational analysis and stereoselective recognition by the VHL E3 ubiquitin ligase for targeted protein degradation
Testa, A., Lucas, X., Castro, G., Chan, K. H., Wright, J., Runcie, A., Gadd, M., Harrison, W. T. A., Ko, E. J., Fletcher, D. & Ciulli, A., 25 Jul 2018, In: Journal of the American Chemical Society. 140, 29, p. 9299-9313 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile36 Citations (Scopus)178 Downloads (Pure) -
3 tera-basepairs as a fundamental limit for robust DNA replication
Al Mamun, M., Albergante, L., Blow, J. J. & Newman, T. J., 30 Jun 2020, In: Physical Biology. 17, 4, 10 p., 046002.Research output: Contribution to journal › Article › peer-review
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3T MRI investigation of cardiac left ventricular structure and function in a UK population: The tayside screening for the prevention of cardiac events (TASCFORCE) study
Gandy, S. J., Lambert, M., Belch, J., Cavin, I., Crowe, E., Littleford, R., Macfarlane, J. A., Matthew, S. Z., Martin, P., Nicholas, R. S., Struthers, A., Sullivan, F., Waugh, S. A., White, R. D., Weir-Mccall, J. R. & Houston, J. G., 11 Oct 2016, In: Journal of Magnetic Resonance Imaging. 44, 5, p. 1186-1196 25267.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)175 Downloads (Pure) -
4.35 kW peak power femtosecond pulse mode-locked VECSEL for supercontinuum generation
Wilcox, K. G., Tropper, A. C., Beere, H. E., Ritchie, D. A., Kunert, B., Heinen, B. & Stolz, W., 28 Jan 2013, In: Optics Express. 21, 2, p. 1599-1605 7 p.Research output: Contribution to journal › Article › peer-review
142 Citations (Scopus) -
4-Acyl Pyrrole Derivatives Yield Novel Vectors for Designing Inhibitors of the Acetyl-Lysine Recognition Site of BRD4(1)
Hügle, M., Lucas, X., Weitzel, G., Ostrovskyi, D., Breit, B., Gerhardt, S., Einsle, O., Günther, S. & Wohlwend, D., 25 Feb 2016, In: Journal of Medicinal Chemistry. 59, 4, p. 1518-1530 13 p.Research output: Contribution to journal › Article › peer-review
37 Citations (Scopus) -
4-Acyl pyrroles: mimicking acetylated lysines in histone code reading
Lucas, X., Wohlwend, D., Hügle, M., Schmidtkunz, K., Gerhardt, S., Schüle, R., Jung, M., Einsle, O. & Günther, S., 23 Dec 2013, In: Angewandte Chemie International Edition. 52, 52, p. 14055-14059 5 p.Research output: Contribution to journal › Article › peer-review
79 Citations (Scopus) -
5-chloroindole: a potent allosteric modulator of the 5-HT3 receptor
Newman, A. . S., Batis, N., Grafton, G., Caputo, F., Brady, C. A., Lambert, J. J., Peters, J. A., Gordon, J., Barnes, N. M., Brain, K. L., Powell, A. D. & Barnes, N. M., 2013, In: British Journal of Pharmacology. 169, 6, p. 1228-1238 11 p.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus) -
5-HTTLPR and Early Childhood Adversities Moderate Cognitive and Emotional Processing in Adolescence
Owens, M., Goodyer, I. M., Wilkinson, P., Bhardwaj, A., Abbott, R., Croudace, T., Dunn, V., Jones, P. B., Walsh, N. D., Ban, M. & Sahakian, B. J., 28 Nov 2012, In: PLoS ONE. 7, 11, 12 p.Research output: Contribution to journal › Article › peer-review
36 Citations (Scopus) -
6-hydroxydopamine (6-OHDA) Oxidative Stress Assay for Observing Dopaminergic Neuron Loss in Caenorhabditis elegans
Offenburger, S-L. & Gartner, A., 20 Sep 2018, In: Bio-Protocol. 8, 18, 12 p., e3025.Research output: Contribution to journal › Article › peer-review
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6-OHDA-induced dopaminergic neurodegeneration in Caenorhabditis elegans is promoted by the engulfment pathway and inhibited by the transthyretin-related protein TTR-33
Offenburger, S-L., Ho, X. Y., Tachie-Menson, T., Coakley, S., Hilliard, M. A. & Gartner, A., 18 Jan 2018, In: PLoS Genetics. 14, 1, p. 1-27 27 p., e1007125.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)229 Downloads (Pure) -
85.7 MHz repetition rate mode-locked semiconductor disk laser: fundamental and soliton bound states
Butkus, M., Viktorov, E. A., Erneux, T., Hamilton, C. J., Maker, G., Malcolm, G. P. A. & Rafailov, E. U., 21 Oct 2013, In: Optics Express. 21, 21, p. 25526-25531 6 p.Research output: Contribution to journal › Article › peer-review
24 Citations (Scopus) -
8-Alkynyl-3-nitroimidazopyridines display potent antitrypanosomal activity against both T. b. brucei and cruzi
Fersing, C., Boudot, C., Castera-Ducros, C., Pinault, E., Hutter, S., Paoli-Lombardo, R., Primas, N., Pedron, J., Seguy, L., Bourgeade-Delmas, S., Sournia-Saquet, A., Stigliani, J. L., Brossas, J. Y., Paris, L., Valentin, A., Wyllie, S., Fairlamb, A. H., Boutet-Robinet, É., Corvaisier, S., Since, M. & 8 others, , 15 Sep 2020, In: European Journal of Medicinal Chemistry. 202, 15 p., 112558.Research output: Contribution to journal › Article › peer-review
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8-Aryl-6-chloro-3-nitro-2-(phenylsulfonylmethyl)imidazo[1,2-a]pyridines as potent antitrypanosomatid molecules bioactivated by type 1 nitroreductases
Fersing, C., Boudot, C., Pedron, J., Hutter, S., Primas, N., Castera-Ducros, C., Bourgeade-Delmas, S., Sournia-Saquet, A., Moreau, A., Cohen, A., Stigliani, J-L., Pratviel, G., Crozet, M. D., Wyllie, S., Fairlamb, A., Valentin, A., Rathelot, P., Azas, N., Courtioux, B., Verhaeghe, P. & 1 others, , 5 Sep 2018, In: European Journal of Medicinal Chemistry. 157, p. 115-126 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)18 Downloads (Pure) -
A 10-year Review of Surgical Management of Dermatofibrosarcoma Protuberans
Durack, A., Gran, S., Gardiner, M. D., Jain, A., Craythorne, E., Proby, C. M., Marsden, J., Harwood, C. A. & Matin, R. N., 29 Jun 2020, In: British Journal of Dermatology.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
A 20-year multicentre outcome analysis of salvage mechanical circulatory support for refractory cardiogenic shock after cardiac surgery
Khorsandi, M., Dougherty, S., Sinclair, A., Buchan, K., MacLennan, F., Bouamra, O., Curry, P., Zamvar, V., Berg, G. & Al-Attar, N., 8 Nov 2016, In: Journal of Cardiothoracic Surgery. 11, p. 1-10 10 p., 151.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)194 Downloads (Pure) -
A 30-Year Clinical and Magnetic Resonance Imaging Observational Study of Multiple Sclerosis and Clinically Isolated Syndromes
Chung, K. K., Altmann, D., Barkhof, F., Miszkiel, K., Brex, P. A., O'Riordan, J., Ebner, M., Prados, F., Cardoso, M. J., Vercauteren, T., Ourselin, S., Thompson, A., Ciccarelli, O. & Chard, D. T., Jan 2020, In: Annals of Neurology. 87, 1, p. 63-74 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)72 Downloads (Pure) -
A 3D numerical approach to assess the temporal evolution of settlement damage to buildings on cavities subject to weathering
Ciantia, M., Castellanza, R. & Fernandez-Mrrodo, J. A., Sep 2018, In: Rock Mechanics and Rock Engineering. 51, 9, p. 2839-2862 24 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)210 Downloads (Pure) -
A 3-D semi-coupled numerical model for fluid-structures-seabed-interaction (FSSI-CAS 3D): model and verification
Ye, J., Jeng, D., Wang, R. & Zhu, C., Jul 2013, In: Journal of Fluids and Structures. 40, p. 148-162 15 p.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
A 3D view of the Taurus star-forming region by Gaia and Herschel: multiple populations related to the filamentary molecular cloud
Roccatagliata, V., Franciosini, E., Sacco, G. G., Randich, S. & Sicilia Aguilar, A., 18 Jun 2020, In: Astronomy and Astrophysics. 638, 10 p., A85.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)20 Downloads (Pure) -
A 3-species competition model for bio-control
Alzahrani, E. O., Davidson, F. A. & Dodds, N., 1 Jun 2012, In: Applied Mathematics and Computation. 218, 19, p. 9690-9698 9 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
A 5 μm image of β Pictoris b at A sub-Jupiter projected separation: Evidence for a misalignment between the planet and the inner, warped disk
Currie, T., Thalmann, C., Matsumura, S., Madhusudhan, N., Burrows, A. & Kuchner, M., 1 Aug 2011, In: Astrophysical Journal Letters. 736, 2, L33.Research output: Contribution to journal › Article › peer-review
40 Citations (Scopus) -
A balanced approach to identifying, prioritising and evaluating all potential consequences of quality improvement: modified Delphi study
Toma, M., Dreischulte, T., Gray, N. M. . & Guthrie, B., Feb 2020, In: BMJ Open. 9, 3, p. 1-11 11 p., e023890.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)147 Downloads (Pure) -
A battle for the skies: applying the European emissions trading system to international aviation
Hartmann, J., 2013, In: Nordic Journal of International Law. 82, 2, p. 187-220Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
ABCB1 (MDR1) induction defines a common resistance mechanism in paclitaxel- and olaparib-resistant ovarian cancer cells
Vaidyanathan, A., Sawers, L., Gannon, A-L., Chakravarty, P., Scott, A. L., Bray, S. E., Ferguson, M. J. & Smith, G., 9 Aug 2016, In: British Journal of Cancer. 115, p. 431-441 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile103 Citations (Scopus)384 Downloads (Pure) -
Abdominal massage plus advice, compared with advice only, for neurogenic bowel dysfunction in MS: a RCT
McClurg, D., Harris, F., Goodman, K., Doran, S., Hagen, S., Treweek, S., Norton, C., Coggrave, M., Norrie, J., Rauchhaus, P., Donnan, P., Emmanuel, A., Manoukian, S. & Mason, H., Oct 2018, In: Health Technology Assessment. 22, 58, p. 1-133 133 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)173 Downloads (Pure) -
Abdominal paragangliomas: Analysis of surgeon's experience
FitzGerald, S. C., Gingell, L. M., Parnaby, C. N., O'Dwyer, P. J. & Connell, J. M., 1 May 2011, In: World Journal of Endocrine Surgery. 3, 2, p. 55-58 4 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
A behavioural approach to specifying interventions: what insights can be gained for the reporting and implementation of interventions to reduce antibiotic use in hospitals?
Duncan, E. M., Charani, E., Clarkson, J. E., Francis, J. J., Gillies, K., Grimshaw, J. M., Kern, W. V., Lorencatto, F., Marwick, C. A., McEwen, J., Möhler, R., Morris, A. M., Ramsay, C. R., Rogers Van Katwyk, S., Rzewuska, M., Skodvin, B., Smith, I., Suh, K. N. & Davey, P. G., 1 May 2020, In: Journal of Antimicrobial Chemotherapy. 75, 5, p. 1338-1346 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)59 Downloads (Pure) -
Aberrant Autophagosome Formation Occurs Upon Small Molecule Inhibition of ULK1 Kinase Activity
Zachari, M., Longo, M. & Ganley, I., Dec 2020, In: Life Science Alliance. 3, 12, p. 1-11 11 p., e202000815.Research output: Contribution to journal › Article › peer-review
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ABHD4-dependent developmental anoikis safeguards the embryonic brain
László, Z. I., Lele, Z., Zöldi, M., Miczán, V., Mógor, F., Simon, G. M., Mackie, K., Kacskovics, I., Cravatt, B. F. & Katona, I., 31 Aug 2020, In: Nature Communications. 11, 16 p., 4363 (2020).Research output: Contribution to journal › Article › peer-review
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Ability of primary care health databases to assess medicinal products discussed by the European Union Pharmacovigilance Risk Assessment Committee
Flynn, R., Hedenmalm, K., Murray-Thomas, T., Pacurariu, A., Arlett, P., Shepherd, H., Myles, P. & Kurz, X., 12 Feb 2020, In: Clinical Pharmacology and Therapeutics. 107, 4, p. 957-965 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)105 Downloads (Pure) -
ABIN1 dysfunction as a genetic basis for lupus nephritis
Caster, D. J., Korte, E. A., Nanda, S. K., McLeish, K. R., Oliver, R. K., G'Sell, R. T., Sheehan, R. M., Freeman, D. W., Coventry, S. C., Kelly, J. A., Guthridge, J. M., James, J. A., Sivils, K. L., Alarcon-Riquelme, M. E., Scofield, R. H., Adrianto, I., Gaffney, P. M., Stevens, A. M., Freedman, B. I., Langefeld, C. D. & 25 others, , 1 Nov 2013, In: Journal of the American Society of Nephrology. 24, 11, p. 1743-1754 12 p.Research output: Contribution to journal › Article › peer-review
Open Access51 Citations (Scopus) -
ABIN2 Function Is Required To Suppress DSS-Induced Colitis by a Tpl2-Independent Mechanism
Nanda, S. K., Nagamori, T., Windheim, M., Amu, S., Aviello, G., Patterson-Kane, J., Arthur, J. S. C., Ley, S. C., Fallon, P. & Cohen, P., 1 Dec 2018, In: Journal of Immunology. 201, 11, p. 3373-3382 10 p.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
A Biocultural Analysis of Mortuary Practices in the Later Anglo-Saxon to Anglo-Norman Black Gate Cemetery, Newcastle-upon-Tyne, England
Swales, D. M., 11 Dec 2018, In: International Journal of Osteoarchaeology. 22 p.Research output: Contribution to journal › Article › peer-review
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A bioinspired autonomous swimming robot as a tool for studying goal-directed locomotion
Manfredi, L., Assaf, T., Mintchev, S., Marrazza, S., Capantini, L., Orofino, S., Ascari, L., Grillner, S., Wallén, P., Ekeberg, O., Stefanini, C. & Dario, P., 2013, In: Biological Cybernetics. 107, 5, p. 513-527 15 p.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
A Black Death mass grave at Thornton Abbey: the discovery and examination of a fourteenth-century rural catastrophe
Willmott, H., Townend, P., Swales, D. M., Poinar, H., Eaton, K. & Klunk, J., Feb 2020, In: Antiquity. 94, 373, p. 179-196 18 p.Research output: Contribution to journal › Article › peer-review
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A blended learning Approach to teaching foreign policy: Student experiences of learning through face-to-face and online discussion and their relationship to academic performance
Bliuc, A-M., Ellis, R. A., Goodyear, P. & Piggott, L., Apr 2011, In: Computers and Education. 56, 3, p. 856-864 9 p.Research output: Contribution to journal › Article › peer-review
43 Citations (Scopus) -
Abnormal neural responses to social exclusion in schizophrenia
Gradin, V. B., Waiter, G., Kumar, P., Stickle, C., Milders, M., Matthews, K., Reid, I., Hall, J. & Steele, J. D., 16 Aug 2012, In: PLoS ONE. 7, 8, p. - 7 p., e42608.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
Abnormal Reward Valuation and Event-Related Connectivity in Unmedicated Major Depressive Disorder
Rupprechter, S., Stankevicius, A., Huys, Q. J. M., Seriès, P. & Steele, D., 7 Jan 2020, In: Psychological Medicine. p. 1-9 9 p.Research output: Contribution to journal › Article › peer-review
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A bonding and damage constitutive model for lightly cemented granular material
Doherty, J. P. & Muir Wood, D., Nov 2020, In: Computers and Geotechnics. 127, 11 p., 103732.Research output: Contribution to journal › Article › peer-review
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