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A missense mutation in the catalytic domain of O-GlcNAc transferase links perturbations in protein O-GlcNAcylation to X-linked intellectual disability
Pravata, V. M., Gundogdu, M., Bartual, S. G., Ferenbach, A. T., Stavridis, M., Õunap, K., Pajusalu, S., Žordania, R., Wojcik, M. H. & van Aalten, D. M. F., 7 Nov 2019, In: FEBS Letters. 594, 4, p. 717-727 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)12 Downloads (Pure) -
A Mixed Analytical/Numerical Method for Velocity and Heat Transfer of Laminar Power-Law Fluids
Li, B., Zheng, L., Lin, P., Wang, Z. & Liao, M., 3 Aug 2016, In: Numerical Mathematics: Theory, Methods and Applications. 9, 3, p. 315-336 22 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
A mixed methods approach to understanding funder trust and due diligence processes in online crowdfunding investment
Jones, H. S. & Moncur, W., Feb 2020, In: ACM Transactions on Social Computing. 3, 1, p. 1-29 29 p., 3.Research output: Contribution to journal › Article › peer-review
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A mixed-methods feasibility study protocol to assess the communication behaviours within the dental health professional-parent-child triad in a general dental practice setting
Yuan, S., Humphris, G. M., Ross, A., MacPherson, L., Zhou, Y. & Freeman, R., 13 Aug 2018, In: Pilot and Feasibility Studies. 4, p. 1-9 9 p., 136.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)174 Downloads (Pure) -
A mobile phone intervention to reduce binge drinking among disadvantaged men: study protocol for a randomised controlled cost-effectiveness trial
Crombie, I. K., Irvine, L., Williams, B., Sniehotta, F. F., Petrie, D., Evans, J. M. M., Emslie, C., Jones, C., Ricketts, I. W., Humphris, G., Norrie, J., Rice, P. & Slane, P. W., 19 Dec 2014, In: Trials. 15, 8 p., 494.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)167 Downloads (Pure) -
A model based criterion for gene expression calls using RNA-seq data
Wagner, G. P., Kin, K. & Lynch, V. J., Sep 2013, In: Theory in Biosciences. 132, 3, p. 159-164 6 p.Research output: Contribution to journal › Article › peer-review
74 Citations (Scopus) -
A Model for (Quasi-)Periodic Multiwavelength Photometric Variability in Young Stellar Objects
Kesseli, A. Y., Petkova, M. A., Wood, K., Whitney, B. A., Hillenbrand, L. A., Gregory, S. G., Stauffer, J. R., Morales-Calderon, M., Rebull, L. & Alencar, S. H. P., Sep 2016, In: Astrophysical Journal. 828, 1, p. 1-15 15 p., 42.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)80 Downloads (Pure) -
A model for dynamic reconfiguration in service-oriented architectures
Fiadeiro, J. L. & Lopes, A., 1 May 2013, In: Software and Systems Modeling. 12, 2, p. 349-367 19 p.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
A model of consultation in prostate cancer care: evidence from a systematic review
Paterson, C. & Nabi, G., 2017, In: Cancer Nursing. 40, 4, p. 276-288 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (Scopus)379 Downloads (Pure) -
A model of the transformative journey into reflexivity: an exploration into students' experiences of critical reflection
Shaw, R., 15 Feb 2013, In: Reflective Practice. 14, 3, p. 319-335 17 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
A Modified AUGIS Delphi Process to Establish Future Research Priorities in Benign Upper Gastrointestinal Surgery
Apr 2020, In: World Journal of Surgery. 44, p. 1216-1222 7 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
A modified Delphi process to establish future research priorities in malignant oesophagogastric surgery
Wilson, M. S. J., Blencowe, N. S., Boyle, C., Knight, S. R., Petty, R., Vohra, R. S. & Underwood, T. J., 16 Dec 2019, In: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland. 6 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
A molecular explanation for the recessive nature of parkin-linked Parkinson's disease
Spratt, D. E., Julio Martinez-Torres, R., Noh, Y. J., Mercier, P., Manczyk, N., Barber, K. R., Aguirre, J. D., Burchell, L., Purkiss, A., Walden, H. & Shaw, G. S., 1 Jan 2013, In: Nature Communications. 4, 12 p., 1983.Research output: Contribution to journal › Article › peer-review
87 Citations (Scopus) -
A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors
Harrison, J. R., Brand, S., Smith, V., Robinson, D. A., Thompson, S., Smith, A., Davies, K., Mok, N., Torrie, L. S., Collie, I., Hallyburton, I., Norval, S., Simeons, F. R. C., Stojanovski, L., Frearson, J. A., Brenk, R., Wyatt, P. G., Gilbert, I. H. & Read, K. D., 12 Sep 2018, In: Journal of Medicinal Chemistry. 61, 18, p. 8374–8389 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)198 Downloads (Pure) -
A monovalent ion in the DNA binding interface of the eukaryotic junction-resolving enzyme GEN1
Liu, Y., Freeman, A. D. J., Déclais, A-C. & Lilley, D. M. J., 16 Nov 2018, In: Nucleic Acids Research. 46, 20, p. 11089-11098 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)110 Downloads (Pure) -
A More Scientific Approach to Applied Economics: Reconstructing Statistical, Analytical Significance, and Correlation Analysis
Altman, M., 28 Feb 2019, In: SSRN Working Paper Series. 23 p.Research output: Contribution to journal › Article
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"A Morning Since Eight of Just Pure Grill": A Multischool Qualitative Study of Student Abuse
Rees, C. E. & Monrouxe, L. V., Nov 2011, In: Academic Medicine: Journal of the Association of American Medical Colleges. 86, 11, p. 1374-1382 9 p.Research output: Contribution to journal › Article › peer-review
46 Citations (Scopus) -
A Morphological identification cell cytotoxicity assay using cytoplasm-localized fluorescent probe (CLFP) to distinguish living and dead cells
Lai, F., Shen, Z., Wen, H., Chen, J., Zhang, X., Lin, P., Yin, D., Cui, H. & Chen, X., 8 Jan 2017, In: Biochemical and Biophysical Research Communications. 482, 2, p. 257-263 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)400 Downloads (Pure) -
A mouse model for functional dissection of TAB1 O-GlcNAcylation
Authier, F., Muha, V. & van Aalten, D. M. F., 27 Aug 2019, In: Wellcome Open Research. 4, 16 p., 128.Research output: Contribution to journal › Article › peer-review
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A moving interface finite element formulation for layered structures
Funari, M. F., Greco, F. & Lonetti, P., 1 Jul 2016, In: Composites Part B: Engineering. 96, p. 325-337 13 p.Research output: Contribution to journal › Article › peer-review
33 Citations (Scopus) -
A moving interface finite element formulation to predict dynamic edge debonding in FRP-strengthened concrete beams in service conditions
Funari, M. F., Spadea, S., Fabbrocino, F. & Luciano, R., Jun 2020, In: Fibers. 8, 6, p. 1-9 9 p., 42.Research output: Contribution to journal › Article › peer-review
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AMP-activated protein kinase: a cellular energy sensor that comes in twelve flavours
Ross, F. A., MacKintosh, C. & Hardie, D. G., 24 Mar 2016, In: FEBS Journal. 283, 16, p. 2987-3001 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile135 Citations (Scopus)112 Downloads (Pure) -
AMP-activated protein kinase: a cellular energy sensor with a key role in metabolic disorders and in cancer
Hardie, D. G., Feb 2011, In: Biochemical Society Transactions. 39, p. 1-13 13 p.Research output: Contribution to journal › Article › peer-review
123 Citations (Scopus) -
AMP-activated protein kinase (AMPK)α2 plays a role in determining the cellular fate of glucose in insulin-resistant mouse skeletal muscle
Lee-Young, R. S., Bonner, J. S., Mayes, W. H., Iwueke, I., Barrick, B. A., Hasenour, C. M., Kang, L. & Wasserman, D. H., Mar 2013, In: Diabetologia. 56, 3, p. 608-617 10 p.Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus) -
AMP-activated protein kinase activator A-769662 increases intracellular calcium and ATP release from astrocytes in an AMPK-independent manner
Vlachaki Walker, J. M., Robb, J. L., Cruz, A. M., Malhi, A., Weightman Potter, P. G., Ashford, M. L. J., McCrimmon, R. J., Ellacott, K. L. J. & Beall, C., 21 Apr 2017, In: Diabetes, Obesity & Metabolism. 19, 7, p. 997-1005 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)290 Downloads (Pure) -
AMP-activated protein kinase inhibits Kv1.5 channel currents of pulmonary arterial myocytes in response to hypoxia and inhibition of mitochondrial oxidative phosphorylation
Moral-Sanz, J., Mahmoud, A. D., Ross, F. A., Eldstrom, J., Fedida, D., Hardie, D. G. & Evans, A. M., 1 Sep 2016, In: Journal of Physiology. 594, 17, p. 4901-4915 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)157 Downloads (Pure) -
AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study
Boyle, J. G., Logan, P. J., Jones, G. C., Small, M., Sattar, N., Connell, J. M. C., Cleland, S. J. & Salt, I. P., 2011, In: Diabetologia. 54, 7, p. 1799-1809 11 p.Research output: Contribution to journal › Article › peer-review
54 Citations (Scopus) -
Amphiphilic oxygenated amorphous carbon-graphite buckypapers with gas sensitivity to polar and non-polar VOCs
Homaeigohar, S., Sep 2019, In: Nanomaterials. 9, 9, p. 1-14 14 p., 1343.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)16 Downloads (Pure) -
AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation
Gowans, G. J., Hawley, S. A., Ross, F. A. & Hardie, D. G., 1 Oct 2013, In: Cell Metabolism. 18, 4, p. 556-566 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile272 Citations (Scopus)159 Downloads (Pure) -
AMPK: opposing the metabolic changes in both tumour cells and inflammatory cells?
Dandapani, M. & Hardie, D. G., Apr 2013, In: Biochemical Society Transactions. 41, 2, p. 687-693 7 p.Research output: Contribution to journal › Article › peer-review
34 Citations (Scopus) -
AMPK: a target for drugs and natural products with effects on both diabetes and cancer
Hardie, D. G., Jul 2013, In: Diabetes. 62, 7, p. 2164-2172 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile263 Citations (Scopus)133 Downloads (Pure) -
AMPK: regulating energy balance at the cellular and whole body levels
Hardie, D. G. & Ashford, M. L. J., Mar 2014, In: Physiology. 29, 2, p. 99-107 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile161 Citations (Scopus)160 Downloads (Pure) -
AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1-Parkin independent manner
Seabright, A. P., Fine, N. H. F., Barlow, J. P., Lord, S. O., Musa, I., Gray, A., Bryant, J. A., Banzhaf, M., Lavery, G. G., Hardie, D. G., Hodson, D. J., Philp, A. & Lai, Y-C., 4 May 2020, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34, 5, p. 6284-6301 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)77 Downloads (Pure) -
AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B
Johanns, M., Lai, Y. C., Hsu, M. F., Jacobs, R., Vertommen, D., Van Sande, J., Dumont, J. E., Woods, A., Carling, D., Hue, L., Viollet, B., Foretz, M. & Rider, M. H., 8 Mar 2016, In: Nature Communications. 7, 10856.Research output: Contribution to journal › Article › peer-review
Open Access54 Citations (Scopus) -
AMPK Causes Cell Cycle Arrest in LKB1-deficient Cells via Activation of CAMKK2
Fogarty, S., Ross, F. A., Vara Ciruelos, D., Gray, A., Gowans, G. J. & Hardie, D. G., 1 Aug 2016, In: Molecular Cancer Research. 14, 8, p. 683-695 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile34 Citations (Scopus)310 Downloads (Pure) -
AMPK dilates resistance arteries via activation of SERCA and BKCa channels in smooth muscle
Schneider, H., Schubert, K. M., Blodow, S., Kreutz, C-P., Erdogmus, S., Wiedenmann, M., Qiu, J., Fey, T., Ruth, P., Lubomirov, L. T., Pfitzer, G., Mederos y Schnitzler, M., Hardie, D. G., Gudermann, T. & Pohl, U., Jul 2015, In: Hypertension. 66, 1, p. 108-116 9 p.Research output: Contribution to journal › Article › peer-review
30 Citations (Scopus) -
AMPK modulates glucose-sensing in insulin-secreting cells by altered phosphotransfer to KATP channels
Beall, C., Watterson, K. R., McCrimmon, R. J. & Ashford, M. L. J., Jun 2013, In: Journal of Bioenergetics and Biomembranes. 45, 3, p. 229-241 13 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
AMPK-sensing energy while talking to other signaling pathways
Hardie, D. G., 2 Dec 2014, In: Cell Metabolism. 20, 6, p. 939-952 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile311 Citations (Scopus)151 Downloads (Pure) -
AMPKα1: a glucose sensor that controls CD8 T-cell memory
Rolf, J., Zarrouk, M., Finlay, D. K., Foretz, M., Viollet, B. & Cantrell, D. A., Apr 2013, In: European Journal of Immunology. 43, 4, p. 889-896 8 p.Research output: Contribution to journal › Article › peer-review
133 Citations (Scopus) -
Amputation-free survival in 17,353 people at high risk for foot ulceration in diabetes: a national observational study
Scottish Diabetes Research Network Epidemiology Group, Vadiveloo, T., Jeffcoate, W., Donnan, P. T., Colhoun, H. C., McGurnaghan, S., Wild, S., McCrimmon, R. & Leese, G. P., Dec 2018, In: Diabetologia. 61, 12, p. 2590-2597 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)183 Downloads (Pure) -
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure
LifeLines Cohort Study, Sung, Y. J., de Las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., Manning, A. K., Brown, M. R., Aschard, H., Feitosa, M. F., Franceschini, N., Lu, Y., Cheng, C-Y., Sim, X., Vojinovic, D. & 40 others, , 1 Aug 2019, In: Human Molecular Genetics. 28, 15, p. 2615-2633 19 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)59 Downloads (Pure) -
A Multicellular Model of Intestinal Crypt Buckling and Fission
Almet, A. A., Hughes, B. D., Landman, K. A., Näthke, I. S. & Osborne, J. M., Feb 2018, In: Bulletin of Mathematical Biology. 80, 2, p. 335-359 25 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)224 Downloads (Pure) -
A Multicenter, Randomized, Placebo-Controlled Trial of Atorvastatin for the Primary Prevention of Cardiovascular Events in Patients With Rheumatoid Arthritis: A multicenter, randomized, placebo controlled trial
Kitas, G. D., Nightingale, P., Armitage, J., Sattar, N., Belch, J. J. F. & Symmons, D. P. M., Sep 2019, In: Arthritis and Rheumatology. 71, 9, p. 1437-1449 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Citations (Scopus)40 Downloads (Pure) -
A multi-centre, parallel group superiority trial of silk therapeutic clothing compared to standard care for the management of eczema in children (CLOTHES Trial): study protocol for a randomised controlled trial
Harrison, E. F., Haines, R. H., Cowdell, F., Sach, T. H., Dean, T., Pollock, I., Burrows, N. P., Buckley, H., Batchelor, J., Williams, H. C., Lawton, S., Brown, S. J., Bradshaw, L. E., Ahmed, A., Montgomery, A. A., Mitchell, E. J. & Thomas, K. S., 2 Sep 2015, In: Trials. 16, 12 p., 390.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)171 Downloads (Pure) -
A multi-centre, prospective epidemiological surveillance study considering ophthalmic complications of functional endoscopic sinus surgery
Burgess, S., Foulds, J., White, P., Foot, B. & Macewen, C., Mar 2020, In: Journal of Laryngology and Otology. 134, 3, p. 228-232 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)40 Downloads (Pure) -
A multicentre parallel-group randomised trial assessing multiparametric MRI characterisation and image-guided biopsy of prostate in men suspected of having prostate cancer: MULTIPROS study protocol
Szewczyk-Bieda, M., Wei, C., Coll, K., Gandy, S., Donnan, P., Ragupathy, S. K. A., Singh, P., Wilson, J. & Nabi, G., 21 Nov 2019, In: Trials. 20, p. 1-8 8 p., 638.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)71 Downloads (Pure) -
A Multi-disciplinary Approach to the Archaeological Investigation of a Bedrock-Dominated Shallow-Marine Landscape: An example from the Bay of Firth, Orkney, UK
Bates, M. R., Nayling, N., Bates, R., Dawson, S., Huws, D. & Wickham-Jones, C., Mar 2013, In: International Journal of Nautical Archaeology. 42, 1, p. 24-43 20 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
A multidisciplinary intervention to reduce antibiotic duration in lower respiratory tract infections
Murray, C., Shaw, A., Lloyd, M., Smith, R. P., Fardon, T. C., Schembri, S. & Chalmers, J. D., Feb 2014, In: Journal of Antimicrobial Chemotherapy. 69, 2, p. 515-518 4 p.Research output: Contribution to journal › Article › peer-review
29 Citations (Scopus) -
A multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24.2, 17q23 and 19q13
Leslie, E. J., Carlson, J. C., Shaffer, J. R., Feingold, E., Wehby, G., Laurie, C. A., Jain, D., Laurie, C. C., Doheny, K. F., McHenry, T., Resick, J., Sanchez, C., Jacobs, J., Emanuele, B., Vieira, A. R., Neiswanger, K., Lidral, A. C., Valencia-Ramirez, L. C., Lopez-Palacio, A. M., Valencia, D. R. & 35 others, , 1 Jul 2016, In: Human Molecular Genetics. 25, 13, p. 2862-2872 11 p.Research output: Contribution to journal › Article › peer-review
86 Citations (Scopus) -
A multifaceted approach to identify non-specific enzyme inhibition: Application to Mycobacterium tuberculosis shikimate kinase
Alturki, M. S., Fuanta, N. R., Jarrard, M. A., Hobrath, J. V., Goodwin, D. C., Rants'o, T. A. & Calderón, A. I., 15 Feb 2018, In: Bioorganic and Medicinal Chemistry Letters. 28, 4, p. 802-808 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)159 Downloads (Pure)