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• Comment/debate

  First person - Leeanne McGurk

  McGurk, L., Jun 2020, In: Journal of Cell Science. 133, 12, 2 p., jcs.248773.

  Research output: Contribution to journal › Comment/debate › peer-review
• Article

  Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila

  Deng, P., Khan, A., Jacobson, D., Sambrani, N., McGurk, L., Li, X., Jayasree, A., Hejatko, J., Shohat-Ophir, G., O'Connell, M. A., Li, J. B. & Keegan, L. P., 27 Mar 2020, In: Nature Communications. 11, 1, p. 1580 1580.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • editing
  • RNA Editing
  • Drosophila
  • Adenosine
  • brain
  7 Citations (Scopus)

  52 Downloads (Pure)

• Drosophila as an in vivo model for human neurodegenerative disease

  McGurk, L., Berson, A. & Bonini, N. M., Oct 2015, In: Genetics. 201, 2, p. 377-402 26 p.

  Research output: Contribution to journal › Article › peer-review

  • Diptera
  • Drosophila
  • Neurodegenerative Diseases
  • Therapeutic Human Experimentation
  • polyglutamine
  122 Citations (Scopus)

• Membrane and synaptic defects leading to neurodegeneration in Adar mutant Drosophila are rescued by increased autophagy

  Khan, A., Paro, S., McGurk, L., Sambrani, N., Hogg, M. C., Brindle, J., Pennetta, G., Keegan, L. P. & O'Connell, M. A., 14 Feb 2020, In: BMC Biology. 18, 1, 16 p., 15.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Synaptic Membranes
  • adenosine deaminase
  • Adenosine Deaminase
  • autophagy
  • mutant
  3 Citations (Scopus)

  50 Downloads (Pure)

• Poly-A binding protein-1 localization to a subset of TDP-43 inclusions in amyotrophic lateral sclerosis occurs more frequently in patients harboring an expansion in C9orf72

  McGurk, L., Lee, V. M., Trojanowksi, J. Q., Van Deerlin, V. M., Lee, E. B. & Bonini, N. M., 1 Sep 2014, In: Journal of Neuropathology and Experimental Neurology. 73, 9, p. 837-845 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Poly(A)-Binding Proteins
  • Amyotrophic Lateral Sclerosis
  • Inclusion Bodies
  • Motor Neurons
  • Sarcoma
  30 Citations (Scopus)

• Protein interacting with C kinase (PICK1) is a suppressor of spinocerebellar ataxia 3-associated neurodegeneration in Drosophila

  McGurk, L. & Bonini, N. M., 1 Jan 2012, In: Human Molecular Genetics. 21, 1, p. 76-84 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Machado-Joseph Disease
  • Protein Kinase C
  • Drosophila
  • polyglutamine
  • Phosphotransferases
  16 Citations (Scopus)

  63 Downloads (Pure)

• TDP-43, a protein central to amyotrophic lateral sclerosis, is destabilized by tankyrase-1 and -2

  McGurk, L., Rifai, O. & Bonini, N. M., 23 Jun 2020, In: Journal of Cell Science. 133, 12

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Tankyrases
  • Amyotrophic Lateral Sclerosis
  • Poly(ADP-ribose) Polymerases
  • RNA-Binding Proteins
  • DNA-Binding Proteins
  1 Citation (Scopus)

  19 Downloads (Pure)

• Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models

  Kim, H. J., Raphael, A. R., Ladow, E. S., Mcgurk, L., Weber, R. A., Trojanowski, J. Q., Lee, V. M. Y., Finkbeiner, S., Gitler, A. D. & Bonini, N. M., Feb 2014, In: Nature Genetics. 46, 2, p. 152-160 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Amyotrophic Lateral Sclerosis
  • Phosphorylation
  • Diptera
  • Ataxin-2
  • Carrier Proteins
  206 Citations (Scopus)