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2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization
Murugesan, D., Ray, P. C., Bayliss, T., Prosser, G. A., Harrison, J. R., Green, K., Soares De Melo, C., Feng, T. S., Street, L. J., Chibale, K., Warner, D. F., Mizrahi, V., Epemolu, O., Scullion, P., Ellis, L., Riley, J., Shishikura, Y., Ferguson, L., Osuna-Cabello, M., Read, K. D. & 10 others, , 8 Jun 2018, In: ACS Infectious Diseases. 4, 6, p. 954-969 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)198 Downloads (Pure) -
3D liquefaction criteria for seabed considering the cohesion and friction of soil
Ye, J., 1 Aug 2012, In: Applied Ocean Research. 37, p. 111-119 9 p.Research output: Contribution to journal › Article › peer-review
25 Citations (Scopus) -
3D Metal printed heat sinks with longitudinally varying lattice structure sizes using direct metal laser sintering
Shamvedi, D., McCarthy, O. J., O’Donoghue, E., Danilenkoff, C., O’Leary, P. & Raghavendra, R., 2018, In: Virtual and Physical Prototyping. 13, 4, p. 301-310 10 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
3D MRI Analysis of the Lower Legs of Treated Idiopathic Congenital Talipes Equinovarus (Clubfoot)
Duce, S. L., D'Alessandro, M., Du, Y., Jagpal, B., Gilbert, F. J., Crichton, L., Barker, S., Collinson, J. M. & Miedzybrodzka, Z., 30 Jan 2013, In: PLoS ONE. 8, 1, 10 p., e54100.Research output: Contribution to journal › Article › peer-review
Open Access13 Citations (Scopus) -
3D-printing based Transducer Holder for Robotic Assisted Ultrasound Guided HIFU
Wang, J., Xiao, X., Huang, Z. & Melzer, A., Jul 2019, In: Procedia Manufacturing. 30, p. 3-10 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
3D-printing 'Ocean Plastic' - Fostering childrens' engagement with sustainability
Vones, K., Allan, D., Lambert, I. & Vettese, S., Sep 2018, In: Materials Today Communications. 16, p. 56-59 4 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
3D Whole body contrast enhanced MRA can quantify and monitor atherosclerosis progression
Khan, F., Weir-Mccall, J., White, R. D., Gandy, S., Ramkumar, P., Belch, J., Struthers, A. & Houston, J., 26 Apr 2015, In: Heart. 101, 2, A17.Research output: Contribution to journal › Article › peer-review
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3D WKB solution for fast magnetoacoustic wave behaviour within a separatrix dome containing a coronal null point
McLaughlin, J. A., Thurgood, J. O., Botha, G. J. J. & Wiggs, J. A., Mar 2019, In: Monthly Notices of the Royal Astronomical Society. 484, 1, p. 1390-1400 11 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
3D zero-thickness coupled interface finite element: Formulation and application
Cerfontaine, B., Dieudonné, A-C., Radu, J-P., Collin, F. & Charlier, R., Sep 2015, In: Computers and Geotechnics. 69, p. 124-140 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile35 Citations (Scopus)221 Downloads (Pure) -
3-Fluoro-4-hydroxyprolines: Synthesis, conformational analysis and stereoselective recognition by the VHL E3 ubiquitin ligase for targeted protein degradation
Testa, A., Lucas, X., Castro, G., Chan, K. H., Wright, J., Runcie, A., Gadd, M., Harrison, W. T. A., Ko, E. J., Fletcher, D. & Ciulli, A., 25 Jul 2018, In: Journal of the American Chemical Society. 140, 29, p. 9299-9313 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile41 Citations (Scopus)192 Downloads (Pure) -
4.35 kW peak power femtosecond pulse mode-locked VECSEL for supercontinuum generation
Wilcox, K. G., Tropper, A. C., Beere, H. E., Ritchie, D. A., Kunert, B., Heinen, B. & Stolz, W., 28 Jan 2013, In: Optics Express. 21, 2, p. 1599-1605 7 p.Research output: Contribution to journal › Article › peer-review
143 Citations (Scopus) -
4-Acyl pyrroles: mimicking acetylated lysines in histone code reading
Lucas, X., Wohlwend, D., Hügle, M., Schmidtkunz, K., Gerhardt, S., Schüle, R., Jung, M., Einsle, O. & Günther, S., 23 Dec 2013, In: Angewandte Chemie International Edition. 52, 52, p. 14055-14059 5 p.Research output: Contribution to journal › Article › peer-review
80 Citations (Scopus) -
4 DOFs hollow soft pneumatic actuator – HOSE
Manfredi, L., Putzu, F., Guler, S., Huan, Y. & Cuschieri, A., 28 Jan 2019, In: Materials Research Express. 6, 4, 045703.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)100 Downloads (Pure) -
4th ESPT Conference: pharmacogenomics and personalized medicine - research progress and clinical implementation
Sipeky, C., Llerena, A., Manolopoulos, V. G., Pearson, E., Mlakar, V., Gozzo, L., Simmaco, M., Marchetti, P., Re, M. D., Stankovic, S., Meyer, U., Cascorbi, I., Ingelman-Sundberg, M., Suarez-Kurtz, G., Marc, J., Katsila, T., Paulmichl, M., Nofziger, C., Ansari, M., Drago, F. & 1 others, , Oct 2019, In: Pharmacogenomics. 20, 15, p. 1063-1069 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
5-chloroindole: a potent allosteric modulator of the 5-HT3 receptor
Newman, A. . S., Batis, N., Grafton, G., Caputo, F., Brady, C. A., Lambert, J. J., Peters, J. A., Gordon, J., Barnes, N. M., Brain, K. L., Powell, A. D. & Barnes, N. M., 2013, In: British Journal of Pharmacology. 169, 6, p. 1228-1238 11 p.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus) -
5-Fluorouracil cardiotoxicity: reversible left ventricular systolic dysfunction with early detection
Iskandar, MZ., Quasem, W. & El-Omar, M., May 2015, In: BMJ Case Reports. 2015, 4 p., bcr2015209347.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)108 Downloads (Pure) -
5-HTTLPR and Early Childhood Adversities Moderate Cognitive and Emotional Processing in Adolescence
Owens, M., Goodyer, I. M., Wilkinson, P., Bhardwaj, A., Abbott, R., Croudace, T., Dunn, V., Jones, P. B., Walsh, N. D., Ban, M. & Sahakian, B. J., 28 Nov 2012, In: PLoS ONE. 7, 11, 12 p.Research output: Contribution to journal › Article › peer-review
36 Citations (Scopus) -
6-hydroxydopamine (6-OHDA) Oxidative Stress Assay for Observing Dopaminergic Neuron Loss in Caenorhabditis elegans
Offenburger, S-L. & Gartner, A., 20 Sep 2018, In: Bio-Protocol. 8, 18, 12 p., e3025.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
6-OHDA-induced dopaminergic neurodegeneration in Caenorhabditis elegans is promoted by the engulfment pathway and inhibited by the transthyretin-related protein TTR-33
Offenburger, S-L., Ho, X. Y., Tachie-Menson, T., Coakley, S., Hilliard, M. A. & Gartner, A., 18 Jan 2018, In: PLoS Genetics. 14, 1, p. 1-27 27 p., e1007125.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)234 Downloads (Pure) -
84 The crystal structure and catalytic mechanism of the twister ribozyme
Lilley, D. M. J., Liu, Y. & Wilson, T. J., May 2015, In: Journal of Biomolecular Structure and Dynamics. 33 , Suppl 1, p. 54-55 2 p.Research output: Contribution to journal › Article › peer-review
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85.7 MHz repetition rate mode-locked semiconductor disk laser: fundamental and soliton bound states
Butkus, M., Viktorov, E. A., Erneux, T., Hamilton, C. J., Maker, G., Malcolm, G. P. A. & Rafailov, E. U., 21 Oct 2013, In: Optics Express. 21, 21, p. 25526-25531 6 p.Research output: Contribution to journal › Article › peer-review
24 Citations (Scopus) -
8-Aryl-6-chloro-3-nitro-2-(phenylsulfonylmethyl)imidazo[1,2-a]pyridines as potent antitrypanosomatid molecules bioactivated by type 1 nitroreductases
Fersing, C., Boudot, C., Pedron, J., Hutter, S., Primas, N., Castera-Ducros, C., Bourgeade-Delmas, S., Sournia-Saquet, A., Moreau, A., Cohen, A., Stigliani, J-L., Pratviel, G., Crozet, M. D., Wyllie, S., Fairlamb, A., Valentin, A., Rathelot, P., Azas, N., Courtioux, B., Verhaeghe, P. & 1 others, , 5 Sep 2018, In: European Journal of Medicinal Chemistry. 157, p. 115-126 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)22 Downloads (Pure) -
A 1.8-kb insertion in the 3′-UTR of RXFP2 is associated with polledness in sheep
Wiedemar, N. & Drögemüller, C., Aug 2015, In: Animal Genetics. 46, 4, p. 457-461 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile26 Citations (Scopus)30 Downloads (Pure) -
A 2 × 2 factorial, randomised, open-label trial to determine the clinical and cost-effectiveness of hypertonic saline (HTS 6%) and carbocisteine for airway clearance versus usual care over 52 weeks in adults with bronchiectasis: a protocol for the CLEAR clinical trial
Bradley, J. M., Anand, R., O'Neill, B., Ferguson, K., Clarke, M., Carroll, M., Chalmers, J., De Soyza, A., Duckers, J., Hill, A. T., Loebinger, M. R., Copeland, F., Gardner, E., Campbell, C., Agus, A., McGuire, A., Boyle, R., McKinney, F., Dickson, N., McAuley, D. F. & 1 others, , 19 Dec 2019, In: Trials. 20, 10 p., 747.Research output: Contribution to journal › Article › peer-review
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A 3D cephalometric protocol for the accurate quantification of the craniofacial symmetry and facial growth
Pinheiro, M., Ma, X., Fagan, M. J., McIntyre, G. T., Lin, P., Sivamurthy, G. & Mossey, P. A., 17 May 2019, In: Journal of Biological Engineering. 13, p. 1-11 11 p., 42.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)124 Downloads (Pure) -
A 3D numerical approach to assess the temporal evolution of settlement damage to buildings on cavities subject to weathering
Ciantia, M., Castellanza, R. & Fernandez-Mrrodo, J. A., Sep 2018, In: Rock Mechanics and Rock Engineering. 51, 9, p. 2839-2862 24 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)215 Downloads (Pure) -
A 3-D semi-coupled numerical model for fluid-structures-seabed-interaction (FSSI-CAS 3D): model and verification
Ye, J., Jeng, D., Wang, R. & Zhu, C., Jul 2013, In: Journal of Fluids and Structures. 40, p. 148-162 15 p.Research output: Contribution to journal › Article › peer-review
28 Citations (Scopus) -
A 3-species competition model for bio-control
Alzahrani, E. O., Davidson, F. A. & Dodds, N., 1 Jun 2012, In: Applied Mathematics and Computation. 218, 19, p. 9690-9698 9 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
A balance of positive and negative regulators determines the pace of the segmentation clock
Wiedermann, G., Bone, R. A., Silva, J. C., Bjorklund, M., Murray, P. J. & Dale, J. K., 10 Sep 2015, In: eLife. 4, 28 p., e05842.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (Scopus)303 Downloads (Pure) -
A battle for the skies: applying the European emissions trading system to international aviation
Hartmann, J., 2013, In: Nordic Journal of International Law. 82, 2, p. 187-220Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
Abcc5 Knockout Mice Have Lower Fat Mass and Increased Levels of Circulating GLP-1
Cyranka, M., Veprik, A., McKay, E. J., van Loon, N., Thijsse, A., Cotter, L., Hare, N., Saibudeen, A., Lingam, S., Pires, E., Larraufie, P., Reimann, F., Gribble, F., Stewart, M., Bentley, E., Lear, P., McCullagh, J., Cantley, J., Cox, R. D. & de Wet, H., Aug 2019, In: Obesity. 27, 8, p. 1292-1304 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)66 Downloads (Pure) -
Abdominal massage plus advice, compared with advice only, for neurogenic bowel dysfunction in MS: a RCT
McClurg, D., Harris, F., Goodman, K., Doran, S., Hagen, S., Treweek, S., Norton, C., Coggrave, M., Norrie, J., Rauchhaus, P., Donnan, P., Emmanuel, A., Manoukian, S. & Mason, H., Oct 2018, In: Health Technology Assessment. 22, 58, p. 1-133 133 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)182 Downloads (Pure) -
Ability of verbal autopsy data to detect deaths due to uncontrolled hyperglycaemia: testing existing methods and development and validation of a novel weighted score
Blackstock, S., Witham, M. D., Wade, A. N., Crampin, A., Beran, D., Ogle, G. D. & Davies, J. I., 18 Oct 2019, In: BMJ Open. 9, 10, p. 1-8 8 p., e026331.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)90 Downloads (Pure) -
ABIN1 dysfunction as a genetic basis for lupus nephritis
Caster, D. J., Korte, E. A., Nanda, S. K., McLeish, K. R., Oliver, R. K., G'Sell, R. T., Sheehan, R. M., Freeman, D. W., Coventry, S. C., Kelly, J. A., Guthridge, J. M., James, J. A., Sivils, K. L., Alarcon-Riquelme, M. E., Scofield, R. H., Adrianto, I., Gaffney, P. M., Stevens, A. M., Freedman, B. I., Langefeld, C. D. & 25 others, , 1 Nov 2013, In: Journal of the American Society of Nephrology. 24, 11, p. 1743-1754 12 p.Research output: Contribution to journal › Article › peer-review
Open Access51 Citations (Scopus) -
ABIN2 Function Is Required To Suppress DSS-Induced Colitis by a Tpl2-Independent Mechanism
Nanda, S. K., Nagamori, T., Windheim, M., Amu, S., Aviello, G., Patterson-Kane, J., Arthur, J. S. C., Ley, S. C., Fallon, P. & Cohen, P., 1 Dec 2018, In: Journal of Immunology. 201, 11, p. 3373-3382 10 p.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
A Biocultural Analysis of Mortuary Practices in the Later Anglo-Saxon to Anglo-Norman Black Gate Cemetery, Newcastle-upon-Tyne, England
Swales, D. M., 11 Dec 2018, In: International Journal of Osteoarchaeology. 22 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
A bioinspired autonomous swimming robot as a tool for studying goal-directed locomotion
Manfredi, L., Assaf, T., Mintchev, S., Marrazza, S., Capantini, L., Orofino, S., Ascari, L., Grillner, S., Wallén, P., Ekeberg, O., Stefanini, C. & Dario, P., 2013, In: Biological Cybernetics. 107, 5, p. 513-527 15 p.Research output: Contribution to journal › Article › peer-review
27 Citations (Scopus) -
Abnormal brain responses to social fairness in depression: an fMRI study using the Ultimatum Game
Gradin, V. B., Pérez, A., MacFarlane, J. A., Cavin, I., Waiter, G., Engelmann, J., Dritschel, B., Pomi, A., Matthews, K. & Steele, J. D., Apr 2015, In: Psychological Medicine. 45, 6, p. 1241-1251 11 p.Research output: Contribution to journal › Article › peer-review
28 Citations (Scopus) -
Abnormal neural responses to social exclusion in schizophrenia
Gradin, V. B., Waiter, G., Kumar, P., Stickle, C., Milders, M., Matthews, K., Reid, I., Hall, J. & Steele, J. D., 16 Aug 2012, In: PLoS ONE. 7, 8, p. - 7 p., e42608.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
A brain-permeable inhibitor of the neurodegenerative disease target kynurenine 3-monooxygenase prevents accumulation of neurotoxic metabolites
Zhang, S., Sakuma, M., Deora, G. S., Levy, C. W., Klausing, A., Breda, C., Read, K. D., Edlin, C. D., Ross, B. P., Wright Muelas, M., Day, P. J., O'Hagan, S., Kell, D. B., Schwarcz, R., Leys, D., Heyes, D. J., Giorgini, F. & Scrutton, N. S., 24 Jul 2019, In: Communications Biology. 2, p. 1-10 10 p., 271.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)120 Downloads (Pure) -
A brief report on perceptions of alcohol and society among Scottish medical students
Steed, H., Groome, M., Rice, P., Simpson, K., Day, A. & Ker, J., 2012, In: Alcohol and Alcoholism. 47, 1, p. 75-78 4 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Absence of curli in soil-persistent Escherichia coli is mediated by a C-di-GMP signaling defect and suggests evidence of biofilm-independent niche specialization
Somorin, Y. M., Vollmerhausen, T., Waters, N., Pritchard, L., Abram, F., Brennan, F. & O'Byrne, C., 22 Jun 2018, In: Frontiers in Microbiology. 9, p. 1-13 13 p., 1340.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)147 Downloads (Pure) -
Absence of potential gadolinium toxicity symptoms following 22,897 gadoteric acid (Dotarem®) examinations, including 3,209 performed on renally insufficient individuals
Young, L., Matthew, S. & Houston, J., Apr 2019, In: European Radiology. 29, 4, p. 1922-1930 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)209 Downloads (Pure) -
Absence of the Tks4 Scaffold Protein Induces Epithelial-Mesenchymal Transition-Like Changes in Human Colon Cancer Cells
Szeder, B., Tárnoki-Zách, J., Lakatos, D., Vas, V., Kudlik, G., Merő, B., Koprivanacz, K., Bányai, L., Hámori, L., Róna, G., Czirók, A., Füredi, A. & Buday, A. L., 29 Oct 2019, In: Cells. 8, 11, 18 p., 1343.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Absolute immunoquantification of the expression of ABC transporters P-glycoprotein, breast cancer resistance protein and multidrug resistance-associated protein 2 in human liver and duodenum
Tucker, T. G. H. A., Milne, A. M., Fournel-Gigleux, S., Fenner, K. S. & Coughtrie, M. W. H., 2012, In: Biochemical Pharmacology. 83, 2, p. 279-285 7 p.Research output: Contribution to journal › Article › peer-review
70 Citations (Scopus) -
Absolute quantitation of brain metabolites with respect to heterogeneous tissue compositions in H-1-MR spectroscopic volumes
Gussew, A., Erdtel, M., Hiepe, P., Rzanny, R. & Reichenbach, J. R., Oct 2012, In: Magnetic Resonance Materials in Physics Biology and Medicine. 25, 5, p. 321-333 13 p.Research output: Contribution to journal › Article › peer-review
45 Citations (Scopus) -
A call for public archives for biological image data
Ellenberg, J., Swedlow, J. R., Barlow, M., Cook, C. E., Sarkans, U., Patwardhan, A., Brazma, A. & Birney, E., 30 Oct 2018, In: Nature Methods. 15, 11, p. 849-854 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile19 Citations (Scopus)166 Downloads (Pure) -
A calming cacophony: social identity can shape the experience of loud noise
Shankar, S., Stevenson, C., Pandey, K., Tewari, S., Hopkins, N. P. & Reicher, S. D., Dec 2013, In: Journal of Environmental Psychology. 36, p. 87-95 9 p.Research output: Contribution to journal › Article › peer-review
29 Citations (Scopus) -
A cardiovascular disease policy model that predicts life expectancy taking into account socioeconomic deprivation
Lewsey, J. D., Lawson, K. D., Ford, I., Fox, K. A. A., Ritchie, L. D., Tunstall-Pedoe, H., Watt, G. C. M., Woodward, M., Kent, S., Neilson, M. & Briggs, A. H., Feb 2015, In: Heart (British Cardiac Society). 101, 3, p. 201-208 8 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
ACARS: Adaptive context - Aware rate selection for DSRC in vehicular networks
Nwizege, K. S. & He, J., 1 Dec 2012, In: International Journal of Simulation: Systems, Science and Technology. 13, 6, p. 13-23 11 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus)