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  Full Activation of the T Cell Receptor Requires Both Clustering and Conformational Changes at CD3

  Minguet, S., Swamy, M., Alarcón, B., Luescher, I. F. & Schamel, W. W. A., 1 Jan 2007, In: Immunity. 26, 1, p. 43-54 12 p.

  Research output: Contribution to journal › Article › peer-review

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  181 Citations (Scopus)

  96 Downloads (Pure)

• Full-field quantitative phase and polarisation-resolved imaging through an optical fibre bundle

  Gordon, G. S. D., Joseph, J., Sawyer, T., Macfaden, A. J., Williams, C., Wilkinson, T. D. & Bohndiek, S. E., 19 Aug 2019, In: Optics Express. 27, 17, p. 23929-23947 19 p.

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  9 Citations (Scopus)

  32 Downloads (Pure)

• Full-Scale Laboratory Testing Of A Geosynthetically Reinforced Soil Railway Structure

  Esen, A. F., Woodward, P. K., Laghrouche, O., Čebašek, T. M., Brennan, A. J., Robinson, S. & Connolly, D. P., May 2021, In: Transportation Geotechnics. 28, 100526.

  Research output: Contribution to journal › Article › peer-review

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  8 Citations (Scopus)

  78 Downloads (Pure)

• Full volume super-resolution imaging of thick mitotic spindle using 3D AO STED microscope

  McGloin, D., Swedlow, J. & Zdankowski, P., 1 Apr 2019, In: Biomedical Optics Express. 10, 4, p. 1999-2009 11 p., #352466.

  Research output: Contribution to journal › Article › peer-review

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  13 Citations (Scopus)

  156 Downloads (Pure)

• Fully automated analysis of Carbohydrate-Deficient Transferrin (CDT) by using a multicapillary electrophoresis system

  Bortolotti, F., De Paoli, G., Pascali, J. P. & Tagliaro, F., 2007, In: Clinica Chimica Acta. 380, 1-2, p. 4-7 4 p.

  Research output: Contribution to journal › Article › peer-review
  32 Citations (Scopus)

• Fully Convolutional Network Ensembles for White Matter Hyperintensities Segmentation in MR Images

  Li, H., Jiang, G., Zhang, J., Wang, R., Wang, Z., Zheng, W-S. & Menze, B., 1 Dec 2018, In: NeuroImage. 183, p. 650-665 16 p.

  Research output: Contribution to journal › Article › peer-review

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  103 Citations (Scopus)

  265 Downloads (Pure)

• Fully Transradial Versus Transfemoral Approach for Percutaneous Intervention of Coronary Chronic Total Occlusions Applying the Hybrid Algorithm: Insights From RECHARGE Registry

  Bakker, E. J., Maeremans, J., Zivelonghi, C., Faurie, B., Avran, A., Walsh, S., Spratt, J. C., Knaapen, P., Hanratty, C. G., Bressollette, E., Kayaert, P., Bagnall, A. J., Egred, M., Smith, D., McEntegart, M. B., Smith, W. H. T., Kelly, P., Irving, J., Smith, E. J., Strange, J. W., & 2 othersDens, J. & Agostoni, P., Sep 2017, In: Circulation: Cardiovascular Interventions. 10, 9, e005255 .

  Research output: Contribution to journal › Article › peer-review

  Open Access
  29 Citations (Scopus)

• Fulvestrant 500 mg versus anastrozole 1 mg for the first-line treatment of advanced breast cancer: follow-up analysis from the randomized 'FIRST' study

  Robertson, J. F. R., Lindemann, J. P. O., Llombart-Cussac, A., Rolski, J., Feltl, D., Dewar, J., Emerson, L., Dean, A. & Ellis, M. J., 2012, In: Breast Cancer Research and Treatment. 136, 2, p. 503-511 9 p.

  Research output: Contribution to journal › Article › peer-review
  146 Citations (Scopus)

• Functional 3D architecture in an intrinsically disordered E3 ligase domain facilitates ubiquitin transfer

  Murphy, P., Xu, Y., Rouse, S. L., Jaffray, E. G., Plechanovova, A., Matthews, S. J., Penedo, J. C. & Hay, R., 30 Jul 2020, In: Nature Communications. 11, 13 p., 3807.

  Research output: Contribution to journal › Article › peer-review

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  4 Citations (Scopus)

  43 Downloads (Pure)

• Functional analysis of a hypomorphic allele shows that MMP14 catalytic activity is the prime determinant of the Winchester syndrome phenotype

  de Vos, I. J. H. M., Tao, E. Y., Ong, S. L. M., Goggi, J. L., Scerri, T., Wilson, G. R., Low, C. G. M., Wong, A. S. W., Grussu, D., Stegmann, A. P. A., van Geel, M., Janssen, R., Amor, D. J., Bahlo, M., Dunn, N. R., Carney, T. J., Lockhart, P. J., Coull, B. & van Steensel, M., 15 Aug 2018, In: Human Molecular Genetics. 27, 16, p. 2775-2788 14 p., ddy168.

  Research output: Contribution to journal › Article › peer-review

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  18 Citations (Scopus)

  135 Downloads (Pure)

• Functional analysis of the EsaB component of the Staphylococcus aureus Type VII secretion system

  Casabona, M. G., Buchanan, G., Zoltner, M., Harkins, C. P., Holden, M. T. G. & Palmer, T., Dec 2017, In: Microbiology. 163, 12, p. 1851-1863 13 p.

  Research output: Contribution to journal › Article › peer-review

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  12 Citations (Scopus)

  205 Downloads (Pure)

• Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry

  Ajuh, P., Kuster, B., Panov, K., Zomerdijk, J. C. B. M., Mann, M. & Lamond, A. I., 2000, In: EMBO Journal. 19, 23, p. 6569-6581 13 p.

  Research output: Contribution to journal › Article › peer-review
  169 Citations (Scopus)

• Functional and genetic analysis of glutathione S-transferase π

  Wolf, C. R., Park, B. K., Kitteringham, N., Otto, D. & Henderson, C. H., 28 Feb 2001, In: Chemico-Biological Interactions. 133, 1-3, p. 280-284 5 p.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• Functional and genomic insights into the pathogenesis of B urkholderia species to rice

  Naughton, L. M., An, S. Q., Hwang, I., Chou, S. H., He, Y. Q., Tang, J. L., Ryan, R. P. & Dow, J. M., 1 Mar 2016, In: Environmental Microbiology. 18, 3, p. 780-790 11 p.

  Research output: Contribution to journal › Article › peer-review
  20 Citations (Scopus)

• Functional and proteomic analysis of a full thickness filaggrin-deficient skin organoid model

  Elias, M. S., Wright, S. C., Nicholson, W. V., Morrison, K. D., Prescott, A. R., Ten Have, S., Whitfield, P. D., Lamond, A. I. & Brown, S. J., 9 Sep 2019, (E-pub ahead of print) In: Wellcome Open Research. 4, p. 134 28 p.

  Research output: Contribution to journal › Article › peer-review

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  74 Downloads (Pure)

• Functional and structural deficits at accumbens synapses in a mouse model of Fragile X

  Neuhofer, D., Henstridge, C. M., Dudok, B., Sepers, M., Lassalle, O., Katona, I. & Manzoni, O. J., 26 Mar 2015, In: Frontiers in Cellular Neuroscience. 9

  Research output: Contribution to journal › Article › peer-review

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  25 Citations (Scopus)

  106 Downloads (Pure)

• Functional CD169 on Macrophages Mediates Interaction with Dendritic Cells for CD8+ T Cell Cross-Priming

  van Dinther, D., Veninga, H., Iborra, S., Borg, E. G. F., Hoogterp, L., Olesek, K., Beijer, M. R., Schetters, S. T. T., Kalay, H., Garcia-Vallejo, J. J., Franken, K. L., Cham, L. B., Lang, K. S., van Kooyk, Y., Sancho, D., Crocker, P. R. & den Haan, J. M. M., 6 Feb 2018, In: Cell Reports. 22, 6, p. 1484-1495 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  70 Citations (Scopus)

  174 Downloads (Pure)

• Functional characterisation of the iron superoxide dismutase gene repertoire in Trypanosoma brucei

  Wilkinson, S. R., Prathalingam, S. R., Taylor, M. C., Ahmed, A., Horn, D. & Kelly, J. M., 15 Jan 2006, In: Free Radical Biology and Medicine. 40, 2, p. 198-209 12 p.

  Research output: Contribution to journal › Article › peer-review
  75 Citations (Scopus)

• Functional characterisation of the regulation of CAAT enhancer binding protein alpha by GSK-3 phosphorylation of Threonines 222/226

  Liu, H. K., Perrier, S., Lipina, C., Finlay, D., McLauchlan, H., Hastie, C. J., Hundal, H. S., Sutherland, C. & Sutherland, C., 6 Apr 2006, In: BMC Molecular Biology. 7, p. - 12 p., 14.

  Research output: Contribution to journal › Article › peer-review
  21 Citations (Scopus)

• Functional Characterization of Class I Trehalose Biosynthesis Genes in Physcomitrella patens

  Phan, T. L. C. H. B., Delorge, I., Avonce, N. & Van Dijck, P., 20 Jan 2020, In: Frontiers in Plant Science. 10, 17 p., 1694.

  Research output: Contribution to journal › Article › peer-review

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  6 Citations (Scopus)

  35 Downloads (Pure)

• Functional characterization of the Υ-aminobutyric acid transporter from mycobacterium smegmatis MC² 155 reveals sodium-driven GABA transport

  Pavić, A., Ji, Y., Serafini, A., Garza-Garcia, A., McPhillie, M. J., Holmes, A. O. M., Sorio de Carvalho, L. P., Wang, Y., Bartlam, M., Goldman, A. & Postis, V. L. G., 25 Jan 2021, In: Journal of Bacteriology. 203, 4, 14 p., e00642-20.

  Research output: Contribution to journal › Article › peer-review

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  2 Citations (Scopus)

  36 Downloads (Pure)

• Functional coexpression of serine protein kinase SRPK1 and its substrate ASF/SF2 in Escherichia coli

  Yue, B. G., Ajuh, P., Akusjärvi, G., Lamond, A. I. & Kreivi, J. P., 1 Mar 2000, In: Nucleic Acids Research. 28, 5, p. e4 1 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  31 Citations (Scopus)

• Functional complexity of the twin-arginine translocase TatC component revealed by site-directed mutagenesis

  Buchanan, G., de Leeuw, E., Stanley, N. R., Wexler, M., Berks, B. C., Sargent, F. & Palmer, T., Mar 2002, In: Molecular Microbiology. 43, 6, p. 1457-1470 14 p.

  Research output: Contribution to journal › Article › peer-review
  83 Citations (Scopus)

• Functional connectivity between the thalamus and postsubiculum: Analysis of evoked responses elicited by stimulation of the laterodorsal thalamic nucleus in anesthetized rats

  Shires, K. L., Hawthorne, J. P., Hope, A. M. J., Dudchenko, P. A., Wood, E. R. & Martin, S. J., Jul 2013, In: Hippocampus. 23, 7, p. 559-569 11 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Functional consequences of nutrient translocation in mycelial fungi

  Boswell, G. P., Jacobs, H., Davidson, F. A., Gadd, G. M. & Ritz, K., 21 Aug 2002, In: Journal of Theoretical Biology. 217, 4, p. 459-477 19 p.

  Research output: Contribution to journal › Article › peer-review
  88 Citations (Scopus)

• Functional consequences of the identification and localisation of cyclooxygenase isoforms in dorsal horn of rat spinal cord

  Grubb, B. D., Willingale, H. L., Gardiner, N. J. & Giblett, S., 1 Dec 1997, In: Advances in Experimental Medicine and Biology. 433, p. 209-212 4 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Functional conservation in human and Drosophila of Metazoan ADAR2 involved in RNA editing: Loss of ADAR1 in insects

  Keegan, L. P., McGurk, L., Palavicini, J. P., Brindle, J., Paro, S., Li, X., Rosenthal, J. J. C. & O'Connell, M. A., 1 Sep 2011, In: Nucleic Acids Research. 39, 16, p. 7249-7262 14 p.

  Research output: Contribution to journal › Article › peer-review

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  44 Citations (Scopus)

  47 Downloads (Pure)

• Functional C-terminally encoded plant peptide (CEP) hormone domains evolved de novo in the plant parasite Rotylenchulus reniformis

  Eves-van den Akker, S., Lilley, C. J., Yusup, H. B., Jones, J. T. & Urwin, P. E., 7 Sep 2016, In: Molecular Plant Pathology. 17, 8, p. 1265-1275 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  29 Citations (Scopus)

  131 Downloads (Pure)

• Functional differences and interactions between phenotypic subpopulations of olfactory ensheathing cells in promoting CNS axonal regeneration

  Kumar, R., Hayat, S., Felts, P., Bunting, S. & Wigley, C., 7 Feb 2005, In: Glia. 50, 1, p. 12-20 9 p.

  Research output: Contribution to journal › Article › peer-review
  50 Citations (Scopus)

• Functional dissection of Adenylate Cyclase R, an inducer of spore encapsulation

  Chen, Z., Schilde, C. & Schaap, P., 31 Dec 2010, In: Journal of Biological Chemistry. 285, 53, p. 41724-41731 8 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Functional dissection of Caenorhabditis elegans CLK-2/TEL2 cell cycle defects during embryogenesis and germline development

  Moser, S. C., von Elsner, S., Buessing, I., Alpi, A., Schnabel, R. & Gartner, A., Apr 2009, In: PLoS Genetics. 5, 4, p. - 15 p., e1000451.

  Research output: Contribution to journal › Article › peer-review
  34 Citations (Scopus)

• Functional disturbance of marrow stromal microenvironment in the myelodysplastic syndromes

  Tauro, S., Hepburn, M. D., Peddie, C. M., Bowen, D. T. & Pippard, M. J., 2002, In: Leukemia. 16, 5, p. 785-790 6 p.

  Research output: Contribution to journal › Article › peer-review
  47 Citations (Scopus)

• Functional diversification of SRSF protein kinase to control ubiquitin-dependent neurodevelopmental signalling

  Bustos, F., Segarra-Fas, A., Nardocci, G., Cassidy, A., Antico, O., Davidson, L., Brandenburg, L., Macartney, T., Toth, R., Hastie, C. J., Moran, J., Gourlay, R., Vargese, J., Soares, R., Montecino, M. & Findlay, G. M., 7 Dec 2020, In: Developmental Cell. 55, p. 629-647.e7 27 p.

  Research output: Contribution to journal › Article › peer-review

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  9 Citations (Scopus)

  64 Downloads (Pure)

• Functional domains of the Xenopus replication licensing factor Cdt1

  Ferenbach, A., Li, A., Brito-Martins, M. & Blow, J. J., 2005, In: Nucleic Acids Research. 33, 1, p. 316-24 9 p.

  Research output: Contribution to journal › Article › peer-review
  55 Citations (Scopus)

• Functional dynamics in the voltage-dependent anion channel

  Villinger, S., Briones, R., Giller, K., Zachariae, U., Lange, A., De Groot, B. L., Griesinger, C., Becker, S. & Zweckstetter, M., 28 Dec 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 52, p. 22546-22551 6 p.

  Research output: Contribution to journal › Article › peer-review
  85 Citations (Scopus)

• Functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders

  Hanzl, A., Casement, R., Imrichova, H., Hughes, S. J., Barone, E., Testa, A., Bauer, S., Wright, J., Brand, M., Ciulli, A. & Winter, G. E., 3 Nov 2022, (E-pub ahead of print) In: Nature Chemical Biology. 26 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  2 Citations (Scopus)

  116 Downloads (Pure)

• Functional effects of genetic variants in the 11β-hydroxylase (CYP11B1) gene

  Barr, M., MacKenzie, S. M., Wilkinson, D. M., Holloway, C. D., Friel, E. C., Miller, S., MacDonald, T., Fraser, R., Connell, J. M. C. & Davies, E., Dec 2006, In: Clinical Endocrinology. 65, 6, p. 816-825 10 p.

  Research output: Contribution to journal › Article › peer-review
  16 Citations (Scopus)

• Functional endoscopic sinus surgery chopstick technique

  Manickavasagam, J., Segaram, S. & Harkness, P., 1 May 2010, In: Laryngoscope. 120, 5, p. 975-977 3 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Functional expression and comparative characterization of nine murine cytochromes P450 by fluorescent inhibition screening

  McLaughlin, L. A., Dickmann, L. J., Wolf, C. R. & Henderson, C. J., Jul 2008, In: Drug Metabolism and Disposition. 36, 7, p. 1322-1331 10 p.

  Research output: Contribution to journal › Article › peer-review
  34 Citations (Scopus)

• Functional expression of cell surface cannabinoid CB₁ receptors on presynaptic inhibitory terminals in cultured rat hippocampal neurons

  Irving, A. J., Coutts, A. A., Harvey, J., Rae, M. G., Mackie, K., Bewick, G. S. & Pertwee, R. G., 1 Jun 2000, In: Neuroscience. 98, 2, p. 253-262 10 p.

  Research output: Contribution to journal › Article › peer-review
  82 Citations (Scopus)

• Functional genomic analysis of epithelioid sarcoma reveals distinct proximal and distal subtype biology

  Rasmussen, S. V., Jin, J. X., Bickford, L. R., Woods, A. D., Sahm, F., Crawford, K. A., Nagamori, K., Goto, H., Torres, K. E., Sidoni, A., Rudzinski, E. R., Thway, K., Jones, R. L., Ciulli, A., Wright, H., Lathara, M., Srinivasa, G., Kannan, K., Huang, P. H., Grünewald, T. G. P., & 2 othersBerlow, N. E. & Keller, C., Jul 2022, In: Clinical and translational medicine. 12, 7, 22 p., e961.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  85 Downloads (Pure)

• Functional herniated choroid plexus in brain parenchyma following VP shunt removal

  El Sheikh, M., Fadelalla, M., Kanodia, A. K., Kouli, O., Peebles, M. & Hossain-Ibrahim, K., 8 Jan 2020, (E-pub ahead of print) In: British Journal of Neurosurgery. 4 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Functional impairment outcomes in clinical trials of different ADHD medications: post hoc responder analyses and baseline subgroup analyses

  Coghill, D. R., Werner-Kiechle, T., Farahbakhshian, S., Bliss, C., Robertson, B. & Huss, M., May 2021, In: European Child & Adolescent Psychiatry. 30, 5, p. 809-821 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  6 Citations (Scopus)

  36 Downloads (Pure)

• Functional interaction of the SNARE protein NtSyp121 in Ca2+ channel gating, Ca2+ transients and ABA signalling of stomatal guard cells

  Sokolovski, S., Hills, A., Gay, R. A. & Blatt, M. R., 2008, In: Molecular Plant. 1, 2, p. 347-358 12 p.

  Research output: Contribution to journal › Article › peer-review
  42 Citations (Scopus)

• Functional interactions between ubiquitin E2 enzymes and TRIM proteins

  Napolitano, L. M., Jaffray, E. G., Hay, R. T. & Meroni, G., 1 Mar 2011, In: Biochemical Journal. 434, p. 309-319 11 p.

  Research output: Contribution to journal › Article › peer-review
  84 Citations (Scopus)

• Functional intercomparison of intraoperative radiotherapy equipment - Photon Radiosurgery System

  Armoogum, K. S., Parry, J. M., Souliman, S. K., Sutton, D. G. & Mackay, C. D., 27 Feb 2007, In: Radiation Oncology . 2, 9 p., 11.

  Research output: Contribution to journal › Article › peer-review
  30 Citations (Scopus)

• Functionalism, Co-operation, Good Faith and the Making of the "Daily- Preventive Justice" in Contract Law Theory and Practice: A Contribution to a Rational Understanding of Good Faith. Evaluations from the South African Perspective

  Siliquini-Cinelli, L., 2014, In: Comparative Law Review. 5, 1, p. 1-49

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Functionalism and representationalism in contemporary urban agendas: a Scottish perspective on city-region branding

  Lloyd, G. & Peel, D., 2008, In: Urban Research and Practice. 1, 1, p. 36-53 18 p.

  Research output: Contribution to journal › Article › peer-review
  20 Citations (Scopus)

• Functional kinomics establishes a critical node of volume-sensitive cation-Cl^- cotransporter regulation in the mammalian brain

  Zhang, J., Gao, G., Begum, G., Wang, J., Khanna, A. R., Shmukler, B. E., Daubner, G. M., De Los Heros, P., Davies, P., Varghese, J., Bhuiyan, M. I. H., Duan, J., Zhang, J., Duran, D., Alper, S. L., Sun, D., Elledge, S. J., Alessi, D. R. & Kahle, K. T., 26 Oct 2016, In: Scientific Reports. 6, p. 1-19 19 p., 35986.

  Research output: Contribution to journal › Article › peer-review

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  35 Citations (Scopus)

  168 Downloads (Pure)

• Functionally distinct groups of inherited PTEN mutations in autism and tumour syndromes

  Spinelli, L., Black, F. M., Berg, J. N., Eickholt, B. J. & Leslie, N. R., Feb 2015, In: Journal of Medical Genetics. 52, 2, p. 128-134 7 p.

  Research output: Contribution to journal › Article
  67 Citations (Scopus)