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  Allosteric targeting of the Fanconi anemia ubiquitin-conjugating enzyme Ube2T by fragment screening

  Morreale, F., Bortoluzzi, A., Chaugule, V., Arkinson, C., Walden, H. & Ciulli, A., 11 May 2017, In: Journal of Medicinal Chemistry. 60, 9, p. 4093-4098 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  • Ubiquitin-Conjugating Enzymes
  • Fanconi Anemia
  • DNA Repair
  • Binding Sites
  • In Vitro Techniques
  8 Citations (Scopus)

  204 Downloads (Pure)

• Alloyed quaternary/binary core/shell quantum dot-graphene oxide nanocomposite: Preparation, characterization and application as a fluorescence “switch ON” probe for environmental pollutants

  Adegoke, O., Montaseri, H., Nsibande, S. A. & Forbes, P. B. C., 5 Oct 2017, In: Journal of Alloys and Compounds. 720, p. 70-78 9 p.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• All patients with diabetes should have annual UACR tests. Why is that so hard?

  Willison, A., Tully, V. & Davey, P., 20 Sep 2016, In: BMJ Quality Improvement Reports. 5, 1, 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  • Albumins
  • Creatinine
  • Urine
  • Patient Participation
  • Kidney Diseases
  161 Downloads (Pure)

• AlmostSignificant: simplifying quality control of high-throughput sequencing data

  Ward, J., Cole, C., Febrer, M. & Barton, G. J., 15 Dec 2016, In: Bioinformatics. 32, 24, p. 3850-3851 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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  • High Throughput
  • Sequencing
  • Quality Control
  • DNA Sequence Analysis
  • Quality control
  2 Citations (Scopus)

  109 Downloads (Pure)

• A localized surface plasmon resonance-amplified immunofluorescence biosensor for ultrasensitive and rapid detection of nonstructural protein 1 of Zika virus

  Takemura, K., Adegoke, O., Suzuki, T. & Park, E. Y., 31 Jan 2019, In: PLoS ONE. 14, 1, p. 1-14 14 p., e0211517.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Zika virus
  • Surface plasmon resonance
  • surface plasmon resonance
  • Zika Virus
  • Surface Plasmon Resonance
  6 Citations (Scopus)

  142 Downloads (Pure)

• A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

  Manning, A., Highland, H. M., Gasser, J., Sim, X., Tukiainen, T., Fontanillas, P., Grarup, N., Rivas, M. A., Mahajan, A., Locke, A. E., Cingolani, P., Pers, T. H., Viñuela, A., Brown, A. A., Wu, Y., Flannick, J., Fuchsberger, C., Gamazon, E. R., Gaulton, K. J., Im, H. K. & 242 others, Teslovich, T. M., Blackwell, T. W., Bork-Jensen, J., Burtt, N. P., Chen, Y., Green, T., Hartl, C., Kang, H. M., Kumar, A., Ladenvall, C., Ma, C., Moutsianas, L., Pearson, R. D., Perry, J. R. B., Rayner, N. W., Robertson, N. R., Scott, L. J., van de Bunt, M., Eriksson, J. G., Jula, A., Koskinen, S., Lehtimäki, T., Palotie, A., Raitakari, O. T., Jacobs, S. B., Wessel, J., Chu, A. Y., Scott, R. A., Goodarzi, M. O., Blancher, C., Buck, G., Buck, D., Chines, P. S., Gabriel, S., Gjesing, A. P., Groves, C. J., Hollensted, M., Huyghe, J. R., Jackson, A. U., Jun, G., Justesen, J. M., Mangino, M., Murphy, J., Neville, M., Onofrio, R., Small, K. S., Stringham, H. M., Trakalo, J., Banks, E., Carey, J., Carneiro, M. O., DePristo, M., Farjoun, Y., Fennell, T., Goldstein, J. I., Grant, G., Hrabé de Angelis, M., Maguire, J., Neale, B. M., Poplin, R., Purcell, S., Schwarzmayr, T., Shakir, K., Smith, J. D., Strom, T. M., Wieland, T., Lindstrom, J., Brandslund, I., Christensen, C., Surdulescu, G. L., Lakka, T. A., Doney, A. S. F., Nilsson, P., Wareham, N. J., Langenberg, C., Varga, T. V., Franks, P. W., Rolandsson, O., Rosengren, A. H., Farook, V. S., Thameem, F., Puppala, S., Kumar, S., Lehman, D. M., Jenkinson, C. P., Curran, J. E., Fowler, S. P., Arya, R., DeFronzo, R. A., Abboud, H. E., Syvänen, A-C., Hicks, P. J., Palmer, N. D., Ng, M. C. Y., Bowden, D. W., Freedman, B. I., Esko, T., Mägi, R., Milani, L., Mihailov, E., Metspalu, A., Narisu, N., Kinnunen, L., Bonnycastle, L. L., Swift, A., Pasko, D., Wood, A. R., Fadista, J., Pollin, T. I., Barzilai, N., Atzmon, G., Glaser, B., Thorand, B., Strauch, K., Peters, A., Roden, M., Müller-Nurasyid, M., Liang, L., Kriebel, J., Illig, T., Grallert, H., Gieger, C., Meisinger, C., Lannfelt, L., Musani, S. K., Griswold, M., Taylor, H. A., Wilson, G., Correa, A., Oksa, H., Scott, W. R., Afzal, U., Tan, S-T., Loh, M., Chambers, J. C., Sehmi, J., Kooner, J. S., Lehne, B., Cho, Y. S., Lee, J-Y., Han, B-G., Käräjämäki, A., Qi, Q., Qi, L., Huang, J., Hu, F. B., Melander, O., Orho-Melander, M., Below, J. E., Aguilar, D., Wong, T. Y., Liu, J., Khor, C-C., Chia, K. S., Lim, W. Y., Cheng, C-Y., Chan, E., Tai, E. S., Aung, T., Linneberg, A., Isomaa, B., Meitinger, T., Tuomi, T., Hakaste, L., Kravic, J., Jørgensen, M. E., Lauritzen, T., Deloukas, P., Stirrups, K. E., Owen, K. R., Farmer, A. J., Frayling, T. M., O'Rahilly, S. P., Walker, M., Levy, J. C., Hodgkiss, D., Hattersley, A. T., Kuulasmaa, T., Stančáková, A., Barroso, I., Bharadwaj, D., Chan, J., Chandak, G. R., Daly, M. J., Donnelly, P. J., Ebrahim, S. B., Elliott, P., Fingerlin, T., Froguel, P., Hu, C., Jia, W., Ma, R. C. W., McVean, G., Park, T., Prabhakaran, D., Sandhu, M., Scott, J., Sladek, R., Tandon, N., Teo, Y. Y., Zeggini, E., Watanabe, R. M., Koistinen, H. A., Kesaniemi, Y. A., Uusitupa, M., Spector, T. D., Salomaa, V., Rauramaa, R., Palmer, C. N. A., Prokopenko, I., Morris, A. D., Bergman, R. N., Collins, F. S., Lind, L., Ingelsson, E., Tuomilehto, J., Karpe, F., Groop, L., Jørgensen, T., Hansen, T., Pedersen, O., Kuusisto, J., Abecasis, G., Bell, G. I., Blangero, J., Cox, N. J., Duggirala, R., Seielstad, M., Wilson, J. G., Dupuis, J., Ripatti, S., Hanis, C. L., Florez, J. C., Mohlke, K. L., Meigs, J. B., Laakso, M., Morris, A. P., Boehnke, M., Altshuler, D., McCarthy, M. I., Gloyn, A. L. & Lindgren, C. M., Jul 2017, In: Diabetes. 66, 7, p. 2019-2032 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Fasting
  • Type 2 Diabetes Mellitus
  • Insulin
  • Exome
  • Population
  23 Citations (Scopus)

  38 Downloads (Pure)

• Altered metabolic parameters in association with antipsychotic medication use in diabetes: A population based case-control study

  Wake, D. J., Broughton, P., Perera, S. M., MacIntyre, D. J. & Leese, G. P., Apr 2016, In: Psychoneuroendocrinology. 66, p. 214-220 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Antipsychotic Agents
  • Case-Control Studies
  • Schizophrenia
  • Population
  • Prescriptions
  5 Citations (Scopus)

  173 Downloads (Pure)

• Altered mitochondrial bioenergetics are responsible for the delay in Wallerian degeneration observed in neonatal mice

  Kline, R. A., Dissanayake, K. N., Hurtado, M. L., Martínez, N. W., Ahl, A., Mole, A. J., Lamont, D. J., Court, F. A., Ribchester, R. R., Wishart, T. M. & Murray, L. M., 1 Oct 2019, In: Neurobiology of Disease. 130, p. 1-16 16 p., 104496.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Wallerian Degeneration
  • Energy Metabolism
  • Axons
  • Oxidative Phosphorylation
  • Wounds and Injuries
  4 Citations (Scopus)

  137 Downloads (Pure)

• Alternate thermoregulation and functional binding of Escherichia coli type 1 fimbriae in environmental and animal isolates

  Marshall, J., Rossez, Y., Mainda, G., Gally, D. L., Daniell, T. J. & Holden, N. J., Nov 2016, In: FEMS Microbiology Letters. 363, 22, p. 1-8 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Mannans
  • Body Temperature Regulation
  • Plant Roots
  • Temperature
  • Escherichia coli
  3 Citations (Scopus)

• Alternative caries management options for primary molars: 2.5-yr outcomes of a randomised clinical trial

  Santamaria, R. M., Innes, N., Machiulskiene, V., Schmoeckel, J., Alkilzy, M. & Splieth, C. H., 20 Dec 2017, In: Caries Research. 51, 6, p. 605-614

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Randomized Controlled Trials
  • Pulpitis
  • Nonparametric Statistics
  • Compomers
  • Therapeutics
  39 Citations (Scopus)

  292 Downloads (Pure)

• Alternative splicing of barley clock genes in response to low temperature: evidence for alternative splicing conservation

  Calixto, C. P. G., Simpson, C. G., Waugh, R. & Brown, J. W. S., 13 Dec 2016, In: PLoS ONE. 11, 12, p. 1-24 24 p., e0168028.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Hordeum
  • alternative splicing
  • Alternative Splicing
  • Conservation
  • Genes
  10 Citations (Scopus)

  162 Downloads (Pure)

• Alternative Splicing of Circadian Clock Genes Correlates With Temperature in Field-Grown Sugarcane

  Dantas, L. L. B., Calixto, C. P. G., Dourado, M. M., Carneiro, M. S., Brown, J. W. S. & Hotta, C. T., 23 Dec 2019, In: Frontiers in Plant Science. 10, p. 1-15 15 p., 1614.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • alternative splicing
  • circadian clocks
  • sugarcane
  • temperature
  • genes
  1 Citation (Scopus)

  103 Downloads (Pure)

• Alternatives to imprisonment in Scotland: policy, strategy and practice

  Freeman, R. & Lloyd, G., 19 Dec 2016, In: Criminology, Victimology and Security Review. 10, 3, p. 60-72

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • imprisonment
  • child custody
  • offense
  • adulthood
  • correctional institution
  543 Downloads (Pure)

• A Macrophage-Pericyte Axis Directs Tissue Restoration via Amphiregulin-Induced Transforming Growth Factor Beta Activation

  Minutti, C. M., Modak, R. V., Macdonald, F., Li, F., Smyth, D. J., Dorward, D. A., Blair, N., Husovsky, C., Muir, A., Giampazolias, E., Dobie, R., Maizels, R. M., Kendall, T. J., Griggs, D. W., Kopf, M., Henderson, N. C. & Zaiss, D. M., 19 Mar 2019, In: Immunity. 50, 3, p. 645-654.e6

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Amphiregulin
  • Pericytes
  • Transforming Growth Factor beta
  • Macrophages
  • Wounds and Injuries
  36 Citations (Scopus)

• A matched comparison study of hepatitis C treatment outcomes in the prison and community setting, and an analysis of the impact of prison release or transfer during therapy

  Aspinall, E. J., Mitchell, W., Schofield, J., Cairns, A., Lamond, S., Bramley, P., Peters, S. E., Valerio, H., Tomnay, J., Goldberg, D. J., Mills, P. R., Barclay, S. T., Fraser, A., Dillon, J. F., Martin, N. K., Hickman, M. & Hutchinson, S. J., Dec 2016, In: Journal of Viral Hepatitis. 23, 12, p. 1009-1016 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Prisons
  • Hepatitis C
  • Prisoners
  • Therapeutics
  • Antiviral Agents
  28 Citations (Scopus)

  190 Downloads (Pure)

• Ambassadors of hope, research pioneers and agents of change: individuals’ expectations and experiences of taking part in a randomised trial of an innovative health technology: longitudinal qualitative study

  Lawton, J., Blackburn, M., Breckenridge, J., Hallowell, N. & Rankin, D., 27 May 2019, In: Trials. 20, p. 1-12 12 p., 289.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Biomedical Technology
  • Longitudinal Studies
  • Blood Glucose
  • Inventions
  • Random Allocation
  1 Citation (Scopus)

  105 Downloads (Pure)

• A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic dermatitis

  Naeem, A. S., Tommasi, C., Cole, C., Brown, S. J., Zhu, Y., Way, B., Willis Owen, S. A. G., Moffatt, M., Cookson, W. O., Harper, J. I., Di, W. L., Brown, S. J., Reinheckel, T. & O'Shaughnessy, R. F. L., Apr 2017, In: Journal of Allergy and Clinical Immunology. 139, 4, p. 1228-1241 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cathepsin H
  • Mechanistic Target of Rapamycin Complex 2
  • filaggrin
  • Mechanistic Target of Rapamycin Complex 1
  • Thymoma
  9 Citations (Scopus)

  214 Downloads (Pure)

• A meta-ethnography of the facilitators and barriers to successful implementation of patient complaints processes in health-care settings

  Scott, D. & Grant, S. M., Apr 2018, In: Health Expectations. 21, 2, p. 508-517 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cultural Anthropology
  • Delivery of Health Care
  • Social Responsibility
  • New Zealand
  • Sweden
  5 Citations (Scopus)

  201 Downloads (Pure)

• A method for automatic segmentation and splitting of hyperspectral images of raspberry plants collected in field conditions

  Williams, D., Britten, A., McCallum, S., Jones, H., Aitkenhead, M., Karley, A., Loades, K., Prashar, A. & Graham, J., 1 Nov 2017, In: Plant Methods. 13, p. 1-12 12 p., 74.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Rubus
  • hyperspectral imagery
  • raspberries
  • methodology
  • reflectance
  9 Citations (Scopus)

  170 Downloads (Pure)

• A methodological approach to assess the hazard of underground cavities subjected to environmental weathering

  Castellanza, R., Lollino, P. & Ciantia, M., Dec 2018, In: Tunnelling and Underground Space Technology. 82, p. 278-292 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Weathering
  • Hazards
  • cavity
  • Rocks
  • weathering
  6 Citations (Scopus)

  41 Downloads (Pure)

• A Method to Evaluate Trainee Progression During Simulation Training at the Urology Simulation Boot Camp (USBC) Course

  Kailavasan, M., Hanchanale, V., Rajpal, S., Morley, R., Mcllhenny, C., Somani, B., Nabi, G., Gowda, R., Jain, S., Biyani, C. S. & Myatt, A., Jan 2019, In: Journal of Surgical Education. 76, 1, p. 215-222 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Simulation Training
  • Urology
  • trainee
  • simulation
  • Mental Competency
  6 Citations (Scopus)

• A Method to Exploit the Structure of Genetic Ancestry Space to Enhance Case-Control Studies

  Bodea, C. A., Neale, B. M., Ripke, S., International IBD Genetics Consortium, Daly, M. J., Devlin, B. & Roeder, K., 5 May 2016, In: American Journal of Human Genetics. 98, 5, p. 857-868 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Genetic Structures
  • Gene Frequency
  • Case-Control Studies
  • Multifactorial Inheritance
  • Bayes Theorem
  6 Citations (Scopus)

• Amine Containing Analogs of Sulindac for Cancer Prevention

  Mathew, B., Hobrath, J. V., Connelly, M. C., Guy, R. K. & Reynolds, R. C., 31 Jan 2018, In: Open Medicinal Chemistry Journal. 12, p. 1-12 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Sulindac
  • sulindac sulfide amide
  • Amines
  • Libraries
  • 3-(5-nitrofuryl)-7-(5-nitrofurfurylidene)-3,3a,4,5,6,7-hexahydro-2H-indazole
  152 Downloads (Pure)

• A minimally invasive tool to study immune response and skin barrier in children with atopic dermatitis

  Hulshof, L., Hack, D. P., Hasnoe, Q. C. J., Dontje, B., Jakasa, I., Riethmüller, C., McLean, W. H. I., van Aalderen, W. M. C., Van't Land, B., Kezic, S., Sprikkelman, A. B. & Middelkamp-Hup, M. A., Mar 2019, In: British Journal of Dermatology. 180, 3, p. 621-630 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Atopic Dermatitis
  • Skin
  • Child
  • Interleukins
  • Biomarkers
  16 Citations (Scopus)

  139 Downloads (Pure)

• Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice

  Loftus, R. M., Assmann, N., Kedia-Mehta, N., O'Brien, K. L., Garcia, A., Gillespie, C., Hukelmann, J. L., Oefner, P. J., Lamond, A. I., Gardiner, C. M., Dettmer, K., Cantrell, D. A., Sinclair, L. V. & Finlay, D. K., 14 Jun 2018, In: Nature Communications. 9, 1, p. 1-15 15 p., 2341.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Oxidative Phosphorylation
  • amino acids
  • mice
  • Lymphocytes
  • Natural Killer Cells
  59 Citations (Scopus)

  171 Downloads (Pure)

• Amino acid secretion influences the size and composition of copper carbonate nanoparticles synthesized by ureolytic fungi

  Liu, F., Csetenyi, L. & Gadd, G., Sep 2019, In: Applied Microbiology and Biotechnology. 103, 17, p. 7217-7230 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • copper carbonate
  • Carbonates
  • Nanoparticles
  • Fungi
  • Minerals
  9 Citations (Scopus)

  107 Downloads (Pure)

• Amino acid substitutions in the human homomeric β3 GABAA receptor that enable activation by GABA

  Gottschald Chiodi, C., Baptista-Hon, D., Hunter, W. & Hales, T., 15 Feb 2019, In: Journal of Biological Chemistry. 294, 7, p. 2375-2385 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • GABA-A Receptors
  • Amino Acid Substitution
  • Substitution reactions
  • gamma-Aminobutyric Acid
  • Chemical activation
  1 Citation (Scopus)

  115 Downloads (Pure)

• A missense mutation in the catalytic domain of O-GlcNAc transferase links perturbations in protein O-GlcNAcylation to X-linked intellectual disability

  Pravata, V. M., Gundogdu, M., Bartual, S. G., Ferenbach, A. T., Stavridis, M., Õunap, K., Pajusalu, S., Žordania, R., Wojcik, M. H. & van Aalten, D. M. F., 7 Nov 2019, In: FEBS Letters. 594, 4, p. 717-727 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • O-GlcNAc transferase
  • Missense Mutation
  • Intellectual Disability
  • Catalytic Domain
  • X ray crystallography
  7 Citations (Scopus)

  12 Downloads (Pure)

• A Mixed Analytical/Numerical Method for Velocity and Heat Transfer of Laminar Power-Law Fluids

  Li, B., Zheng, L., Lin, P., Wang, Z. & Liao, M., 3 Aug 2016, In: Numerical Mathematics: Theory, Methods and Applications. 9, 3, p. 315-336 22 p.

  Research output: Contribution to journal › Article › peer-review

  • Power-law Fluid
  • Analytical Methods
  • Heat Transfer
  • Boundary layers
  • Boundary Layer
  6 Citations (Scopus)

• A mixed-methods feasibility study protocol to assess the communication behaviours within the dental health professional-parent-child triad in a general dental practice setting

  Yuan, S., Humphris, G. M., Ross, A., MacPherson, L., Zhou, Y. & Freeman, R., 13 Aug 2018, In: Pilot and Feasibility Studies. 4, p. 1-9 9 p., 136.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Dental General Practices
  • Feasibility Studies
  • Communication
  • Tooth
  • Health
  3 Citations (Scopus)

  174 Downloads (Pure)

• A Model for (Quasi-)Periodic Multiwavelength Photometric Variability in Young Stellar Objects

  Kesseli, A. Y., Petkova, M. A., Wood, K., Whitney, B. A., Hillenbrand, L. A., Gregory, S. G., Stauffer, J. R., Morales-Calderon, M., Rebull, L. & Alencar, S. H. P., Sep 2016, In: Astrophysical Journal. 828, 1, p. 1-15 15 p., 42.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • hot spot
  • young
  • light curve
  • accretion
  • stars
  8 Citations (Scopus)

  82 Downloads (Pure)

• A model of consultation in prostate cancer care: evidence from a systematic review

  Paterson, C. & Nabi, G., 2017, In: Cancer Nursing. 40, 4, p. 276-288 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Prostatic Neoplasms
  • Systematic Reviews
  • Referral and Consultation
  • Self-Management
  • Nurse Specialists
  13 Citations (Scopus)

  380 Downloads (Pure)

• A modified Delphi process to establish future research priorities in malignant oesophagogastric surgery

  Wilson, M. S. J., Blencowe, N. S., Boyle, C., Knight, S. R., Petty, R., Vohra, R. S. & Underwood, T. J., 16 Dec 2019, In: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland. 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Neoplasms
  • Consensus
  • Surgeons
  • Ireland
  • Genomics
  2 Citations (Scopus)

• A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors

  Harrison, J. R., Brand, S., Smith, V., Robinson, D. A., Thompson, S., Smith, A., Davies, K., Mok, N., Torrie, L. S., Collie, I., Hallyburton, I., Norval, S., Simeons, F. R. C., Stojanovski, L., Frearson, J. A., Brenk, R., Wyatt, P. G., Gilbert, I. H. & Read, K. D., 12 Sep 2018, In: Journal of Medicinal Chemistry. 61, 18, p. 8374–8389 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • glycylpeptide N-tetradecanoyltransferase
  • African Trypanosomiasis
  • Crystallography
  • Trypanosoma brucei brucei
  • Central Nervous System Diseases
  18 Citations (Scopus)

  198 Downloads (Pure)

• A monovalent ion in the DNA binding interface of the eukaryotic junction-resolving enzyme GEN1

  Liu, Y., Freeman, A. D. J., Déclais, A-C. & Lilley, D. M. J., 16 Nov 2018, In: Nucleic Acids Research. 46, 20, p. 11089-11098 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Ions
  • DNA
  • Substrate Specificity
  • Enzymes
  • Catalytic Domain
  3 Citations (Scopus)

  110 Downloads (Pure)

• A More Scientific Approach to Applied Economics: Reconstructing Statistical, Analytical Significance, and Correlation Analysis

  Altman, M., 28 Feb 2019, In: SSRN Working Paper Series. 23 p.

  Research output: Contribution to journal › Article

  • statistical significance
  • economics
  • causality
  • persistence
  • literature

• A Morphological identification cell cytotoxicity assay using cytoplasm-localized fluorescent probe (CLFP) to distinguish living and dead cells

  Lai, F., Shen, Z., Wen, H., Chen, J., Zhang, X., Lin, P., Yin, D., Cui, H. & Chen, X., 8 Jan 2017, In: Biochemical and Biophysical Research Communications. 482, 2, p. 257-263 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cytotoxicity
  • Assays
  • Fluorescent Dyes
  • Cytoplasm
  • Cells
  10 Citations (Scopus)

  400 Downloads (Pure)

• A mouse model for functional dissection of TAB1 O-GlcNAcylation

  Authier, F., Muha, V. & van Aalten, D. M. F., 27 Aug 2019, In: Wellcome Open Research. 4, 16 p., 128.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Dissection
  • Carrier Proteins
  • Phosphotransferases
  • Phenotype
  • Medical problems
  14 Downloads (Pure)

• A moving interface finite element formulation for layered structures

  Funari, M. F., Greco, F. & Lonetti, P., 1 Jul 2016, In: Composites Part B: Engineering. 96, p. 325-337 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Debonding
  • Crack propagation
  • Composite materials
  33 Citations (Scopus)

• AMP-activated protein kinase: a cellular energy sensor that comes in twelve flavours

  Ross, F. A., MacKintosh, C. & Hardie, D. G., 24 Mar 2016, In: FEBS Journal. 283, 16, p. 2987-3001 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Flavors
  • AMP-Activated Protein Kinases
  • Protein Isoforms
  • Gene encoding
  • Tumors
  135 Citations (Scopus)

  112 Downloads (Pure)

• AMP-activated protein kinase activator A-769662 increases intracellular calcium and ATP release from astrocytes in an AMPK-independent manner

  Vlachaki Walker, J. M., Robb, J. L., Cruz, A. M., Malhi, A., Weightman Potter, P. G., Ashford, M. L. J., McCrimmon, R. J., Ellacott, K. L. J. & Beall, C., 21 Apr 2017, In: Diabetes, Obesity & Metabolism. 19, 7, p. 997-1005 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • A 769662
  • AMP-Activated Protein Kinases
  • Astrocytes
  • Adenosine Triphosphate
  • Calcium
  14 Citations (Scopus)

  290 Downloads (Pure)

• AMP-activated protein kinase inhibits K_v1.5 channel currents of pulmonary arterial myocytes in response to hypoxia and inhibition of mitochondrial oxidative phosphorylation

  Moral-Sanz, J., Mahmoud, A. D., Ross, F. A., Eldstrom, J., Fedida, D., Hardie, D. G. & Evans, A. M., 1 Sep 2016, In: Journal of Physiology. 594, 17, p. 4901-4915 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Oxidative Phosphorylation
  • Muscle Cells
  • Hypoxia
  • Lung
  15 Citations (Scopus)

  157 Downloads (Pure)

• Amphiphilic oxygenated amorphous carbon-graphite buckypapers with gas sensitivity to polar and non-polar VOCs

  Homaeigohar, S., Sep 2019, In: Nanomaterials. 9, 9, p. 1-14 14 p., 1343.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Amorphous carbon
  • Volatile Organic Compounds
  • Graphite
  • Volatile organic compounds
  • Gases
  3 Citations (Scopus)

  16 Downloads (Pure)

• AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B

  Johanns, M., Lai, Y. C., Hsu, M. F., Jacobs, R., Vertommen, D., Van Sande, J., Dumont, J. E., Woods, A., Carling, D., Hue, L., Viollet, B., Foretz, M. & Rider, M. H., 8 Mar 2016, In: Nature Communications. 7, 10856.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • cyclic AMP
  • Phosphorylation
  • adenosine monophosphate
  • Type 4 Cyclic Nucleotide Phosphodiesterase
  • phosphorylation
  54 Citations (Scopus)

• AMPK Causes Cell Cycle Arrest in LKB1-deficient Cells via Activation of CAMKK2

  Fogarty, S., Ross, F. A., Vara Ciruelos, D., Gray, A., Gowans, G. J. & Hardie, D. G., 1 Aug 2016, In: Molecular Cancer Research. 14, 8, p. 683-695 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Cell Cycle Checkpoints
  • Null Lymphocytes
  • Calcimycin
  • Phosphorylation
  34 Citations (Scopus)

  311 Downloads (Pure)

• Amputation-free survival in 17,353 people at high risk for foot ulceration in diabetes: a national observational study

  Scottish Diabetes Research Network Epidemiology Group, Vadiveloo, T., Jeffcoate, W., Donnan, P. T., Colhoun, H. C., McGurnaghan, S., Wild, S., McCrimmon, R. & Leese, G. P., Dec 2018, In: Diabetologia. 61, 12, p. 2590-2597 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Amputation
  • Ulcer
  • Foot
  • Observational Studies
  • Scotland
  15 Citations (Scopus)

  188 Downloads (Pure)

• A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

  LifeLines Cohort Study, Sung, Y. J., de Las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., Manning, A. K., Brown, M. R., Aschard, H., Feitosa, M. F., Franceschini, N., Lu, Y., Cheng, C-Y., Sim, X., Vojinovic, D. & 40 others, Marten, J., Musani, S. K., Kilpeläinen, T. O., Richard, M. A., Aslibekyan, S., Bartz, T. M., Dorajoo, R., Li, C., Liu, Y., Rankinen, T., Smith, A. V., Tajuddin, S. M., Tayo, B. O., Zhao, W., Zhou, Y., Matoba, N., Sofer, T., Alver, M., Amini, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Giulianini, F., Goel, A., Harris, S. E., Hartwig, F. P., Connell, J. M., Smith, B. H., Rotter, J. I., Franks, P. W., Rice, K., Elliott, P., Caulfield, M. J., Gauderman, W. J., Munroe, P. B., Rao, D. C. & Morrison, A. C., 1 Aug 2019, In: Human Molecular Genetics. 28, 15, p. 2615-2633 19 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Arterial Pressure
  • Smoking
  • Genome
  • Blood Pressure
  • Genes
  4 Citations (Scopus)

  61 Downloads (Pure)

• A Multicellular Model of Intestinal Crypt Buckling and Fission

  Almet, A. A., Hughes, B. D., Landman, K. A., Näthke, I. S. & Osborne, J. M., Feb 2018, In: Bulletin of Mathematical Biology. 80, 2, p. 335-359 25 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • intestinal crypts
  • buckling
  • Buckling
  • Organoids
  • Tissue
  3 Citations (Scopus)

  226 Downloads (Pure)

• A Multicenter, Randomized, Placebo-Controlled Trial of Atorvastatin for the Primary Prevention of Cardiovascular Events in Patients With Rheumatoid Arthritis: A multicenter, randomized, placebo controlled trial

  Kitas, G. D., Nightingale, P., Armitage, J., Sattar, N., Belch, J. J. F. & Symmons, D. P. M., Sep 2019, In: Arthritis and Rheumatology. 71, 9, p. 1437-1449 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Atorvastatin
  • Primary Prevention
  • Rheumatoid Arthritis
  • Placebos
  • Randomized Controlled Trials
  30 Citations (Scopus)

  40 Downloads (Pure)

• A multicentre parallel-group randomised trial assessing multiparametric MRI characterisation and image-guided biopsy of prostate in men suspected of having prostate cancer: MULTIPROS study protocol

  Szewczyk-Bieda, M., Wei, C., Coll, K., Gandy, S., Donnan, P., Ragupathy, S. K. A., Singh, P., Wilson, J. & Nabi, G., 21 Nov 2019, In: Trials. 20, p. 1-8 8 p., 638.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Image-Guided Biopsy
  • Prostate
  • Prostatic Neoplasms
  • Biopsy
  • Magnetic Resonance Imaging
  2 Citations (Scopus)

  71 Downloads (Pure)