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Author

  • Chim Lang
Abstract

P6505 Urinary desmosine, an elastin-specific degradation product is associated with maximum aortic root size and aortic z-scores in patients with bicuspid aortic valve

Iskandar, Z., Huang, J. T. J., Mordi, I., Miller, L. D., Chin, C., Goudie, D., Mcwilliam, C., Berg, J., Neagoie, A., Lang, C. C. & Choy, A. M., 21 Oct 2019, p. ehz746.1095.

Research output: Contribution to conferenceAbstract

Article

Adverse prognosis associated with asymmetric myocardial thickening in aortic stenosis

Kwiecinski, J., Chin, C. W. L., Everett, R. J., White, A. C., Semple, S. S., Yeung, E., Jenkins, W. J., Shah, A. S. V., Koo, M., Mirsadraee, S., Lang, C. C., Mills, N., Prasad, S. K., Jansen, M. A., Japp, A., Newby, D. E. & Dweck, M. R., 30 Mar 2017, In : European Heart Journal - Cardiovascular Imaging. 10 p., jex052.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
167 Downloads (Pure)

Allopurinol treatment adversely impacts left ventricular mass regression in patients with well-controlled hypertension

Gingles, C., Symon, R., Gandy, S., Struthers, A., Houston, G., MacDonald, T., Lang, C., Donnan, P. & George, J., Dec 2019, In : Journal of Hypertension. 37, 12, p. 2481-2489 9 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
156 Downloads (Pure)

A network analysis to identify pathophysiological pathways distinguishing ischaemic from non-ischaemic heart failure

Sama, I. E., Woolley, R. J., Nauta, J. F., Romaine, S. P. R., Tromp, J., Ter Maaten, J. M., van der Meer, P., Lam, C. S. P., Samani, N. J., Ng, L. L., Metra, M., Dickstein, K., Anker, S. D., Zannad, F., Lang, C. C., Cleland, J. G. F., van Veldhuisen, D. J., Hillege, H. L. & Voors, A. A., May 2020, In : European Journal of Heart Failure. 22, 5, p. 821-833 13 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
21 Downloads (Pure)

Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status

Cameron, A. R., Morrison, V., Levin, D., Mohan, M., Forteath, C., Beall, C., McNeilly, A. D., Balfour, D. J. K., Savinko, T., Wong, A. K. F., Viollet, B., Sakamoto, K., Fagerholm, S. C., Foretz, M., Lang, C. C. & Rena, G., 19 Aug 2016, In : Circulation Research. 119, 5, p. 652-665 14 p.

Research output: Contribution to journalArticle

Open Access
File
148 Citations (Scopus)
273 Downloads (Pure)

A Randomised Controlled Trial of a Facilitated Home-Based Rehabilitation Intervention in Patients with Heart Failure with Preserved Ejection Fraction and their Caregivers: The REACH-HFpEF Pilot Study

Lang, C. C., Smith, K., Wingham, J., Eyre, V., Greaves, C. J., Warren, F. C., Green, C., Jolly, K., Davis, R. C., Doherty, P., Miles, J., Britten, N., Abraham, C., Van Lingen, R., Singh, S., Paul, K., Hillsdon, M., Sadler, S., Hayward, C., Dalal Hayes, M. & 2 others, Taylor, R. S. . & REACH-HF investigators, 9 Apr 2018, In : BMJ Open. 8, 4, p. 1-12 12 p., e019649.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
148 Downloads (Pure)
Open Access
File
18 Downloads (Pure)

A Randomized Controlled Trial of Metformin on Left Ventricular Hypertrophy in Patients with Coronary Artery Disease without Diabetes: The MET-REMODEL Trial

Mohan, M., Al-Talabany, S., McKinnie, A., Mordi, I., Singh, J., Gandy, S., Baig, F., Hussain, M. S. ., Bhalraam, U., Khan, F., Choy, A., Matthew, S., Houston, G., Struthers, A., George, J. & Lang, C. C., 1 Nov 2019, In : European Heart Journal. 40, 41, p. 3409-3417 9 p.

Research output: Contribution to journalArticle

Open Access
File
19 Citations (Scopus)
98 Downloads (Pure)

ASPIRE-3-PREVENT: a cross-sectional survey of preventive care after a coronary event across the UK

Jennings, C. S., Kotseva, K., Bassett, P., Adamska, A., Wood, D. & ASPIRE-3-PREVENT Investigators, 29 Apr 2020, In : Open Heart. 7, 1, p. 1-10 10 p., e001196.

Research output: Contribution to journalArticle

Open Access
File
22 Downloads (Pure)

Association of Chromosome 9p21 with Subsequent Coronary Heart Disease events: A GENIUS-CHD study of individual participant data

CARDIoGRAMplusC4D Consortium, Patel, R. S., Schmidt, A. F., Tragante, V., McCubrey, R. O., Holmes, M. V., Howe, L. J., Direk, K., Åkerblom, A., Leander, K., Virani, S. S., Kaminski, K. A., Muehlschlegel, J. D., Dubé, M. P., Allayee, H., Almgren, P., Alver, M., Baranova, E. V., Behlouli, H., Boeckx, B. & 31 others, Braund, P. S., Breitling, L. P., Delgado, G., Duarte, N. E., Dufresne, L., Eriksson, N., Foco, L., Gijsberts, C. M., Gong, Y., Hartiala, J., Heydarpour, M., Hubacek, J. A., Kleber, M., Kofink, D., Kuukasjärvi, P., Lee, V. V., Leiherer, A., Lenzini, P. A., Levin, D., Lyytikäinen, L. P., Martinelli, N., Mons, U., Nelson, C. P., Nikus, K., Pilbrow, A. P., Ploski, R., Sun, Y. V., Tanck, M. W. T., Mordi, I. R., Palmer, C. N. & Lang, C. C., Apr 2019, In : Circulation: Genomic and Precision Medicine. 12, 4, p. 161-172 12 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
10 Downloads (Pure)

Association of Factor V Leiden with Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data

Mahmoodi, B. K., Tragante, V., Kleber, M. E., Holmes, M. V., Schmidt, A. F., McCubrey, R. O., Howe, L. J., Direk, K., Allayee, H., Baranova, E. V., Braund, P. S., Delgado, G. E., Eriksson, N., Gijsberts, C. M., Gong, Y., Hartiala, J., Heydarpour, M., Pasterkamp, G., Kotti, S., Kuukasjärvi, P. & 64 others, Lenzini, P. A., Levin, D., Lyytikäinen, L-P., Muehlschlegel, J. D., Nelson, C. P., Nikus, K., Pilbrow, A. P., Tang, W. H. W., van der Laan, S. W., van Setten, J., Vilmundarson, R. O., Deanfield, J., Deloukas, P., Dudbridge, F., James, S., Mordi, I. R., Teren, A., Bergmeijer, T. O., Body, S. C., Bots, M., Burkhardt, R., Cooper-DeHoff, R. M., Cresci, S., Danchin, N., Doughty, R. N., Grobbee, D. E., Hagström, E., Hazen, S. L., Held, C., Hoefer, I. E., Hovingh, G. K., Johnson, J. A., Kaczor, M. P., Kähönen, M., Klungel, O. H., Laurikka, J. O., Lehtimäki, T., Maitland-van der Zee, A. H., McPherson, R., Palmer, C. N., Kraaijeveld, A. O., Pepine, C. J., Sanak, M., Sattar, N., Scholz, M., Simon, T., Spertus, J. A., Stewart, A. F. R., Szczeklik, W., Thiery, J., Visseren, F. L. J., Waltenberger, J., Richards, A. M., Lang, C. C., Cameron, V. A., Åkerblom, A., Pare, G., März, W., Samani, N. J., Hingorani, A. D., Ten Berg, J. M., Wallentin, L., Asselbergs, F. W. & Patel, R., 11 Aug 2020, In : Circulation. 142, 6, p. 546-555 10 p.

Research output: Contribution to journalArticle

Association with outcomes and response to treatment of trimethylamine N-oxide in heart failure (from BIOSTAT-CHF)

Suzuki, T., Yazaki, Y., Voors, A. A., Jones, D. J. L., Chan, D. C. S., Anker, S. D., Cleland, J. G. F., Dickstein, K., Filippatos, G. S., Hillege, H. L., Lang, C., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H., Metra, M. & Ng, L. L., 29 Oct 2018, In : European Journal of Heart Failure. 10 p.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
72 Downloads (Pure)

A systems BIOlogy Study to TAilored Treatment in Chronic Heart Failure: Rationale, design, and baseline characteristics of BIOSTAT-CHF

Voors, A. A., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., van der Harst, P., Hillege, H. L., Lang, C. C., ter Maaten, J. M., Ng, L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H. & Metra, M., 20 Jun 2016, In : European Journal of Heart Failure. 18, 6, p. 716-726 11 p.

Research output: Contribution to journalArticle

69 Citations (Scopus)

Bio-adrenomedullin as a marker of congestion in patients with new-onset and worsening heart failure

ter Maaten, J. M., Kremer, D., Demissei, B., Struck, J., Bergmann, A., Anker, S. D., Ng, L. L., Dickstein, K., Metra, M., Samani, N. J., Romaine, S. P. R., Cleland, J. G. F., Girerd, N., Lang, C. C., van Veldhuisen, D. J. & Voors, A. A., 20 Jun 2019, In : European Journal of Heart Failure. 21, 6, p. 732-743 12 p.

Research output: Contribution to journalArticle

Open Access
File
12 Citations (Scopus)
188 Downloads (Pure)

Biomarker-Guided Versus Guideline-Based Treatment of Patients With Heart Failure: Results From BIOSTAT-CHF

Ouwerkerk, W., Zwinderman, A. H., Ng, L. L., Demissei, B., Hillege, H. L., Zannad, F., van Veldhuisen, D. J., Samani, N. J., Ponikowski, P., Metra, M., ter Maaten, J. M., Lang, C., van der Harst, P., Filippatos, G. S., Dickstein, K., Cleland, J. G. F., Anker, S. D. & Voors, A. A., 30 Jan 2018, In : Journal of the American College of Cardiology. 71, 4, p. 386-398 13 p.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
269 Downloads (Pure)

Cardiovascular Effects of Switching from Tobacco Cigarettes to Electronic Cigarettes

George, J., Hussain, M., Vadiveloo, T., Ireland, S., Hopkinson, P., Struthers, A. D., Donnan, P. T., Khan, F. & Lang, C. C., 24 Dec 2019, In : Journal of the American College of Cardiology. 74, 25, p. 3112-3120 9 p.

Research output: Contribution to journalArticle

Open Access
File
22 Citations (Scopus)
64 Downloads (Pure)

Circulating plasma concentrations of ACE2 in men and women with heart failure and effects of renin-angiotensin-aldosterone-inhibitors

Sama, I. E., Ravera, A., Santema, B. T., van Goor, H., ter Maaten, J. M., Cleland, J. G. F., Rienstra, M., Friedrich, A. W., Samani, N. J., Ng, L. L., Dickstein, K., Lang, C. C., Filippatos, G., Anker, S. D., Ponikowski, P., Metra, M., van Veldhuisen, D. J. & Voors, A. A., 14 May 2020, In : European Heart Journal. 41, 19, p. 1810-1817 8 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

Clinical correlates and outcome associated with changes in 6-Minute Walking Distance in Patients with Heart Failure: findings from the BIOSTAT-CHF study

Ferreira, J. P., Metra, M., Anker, S. D., Dickstein, K., Lang, C., Ng, L. L., Samani, N. J., Cleland, J. G. F., van Veldhuisen, D. J., Voors, A. A. & Zannad, F., Feb 2019, In : European Journal of Heart Failure. 21, 2, p. 218-226 9 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
111 Downloads (Pure)

Clinical Determinants and Prognostic Implications of Renin and Aldosterone in Patients with Symptomatic Heart Failure

BIOSTAT consortium, Kobayashi, M., ter Maaten, J. M., Stienen, S., Voors, A. A., Duarte, K., Lamiral, Z., Girerd, N., Rossignol, P., Zannad, F. & Ferreira, J. P., 1 Jun 2020, In : ESC Heart Failure. 7, 3, p. 953-963 11 p.

Research output: Contribution to journalArticle

Open Access
File
27 Downloads (Pure)

Clinical Role of CA125 in Worsening Heart Failure: A BIOSTAT-CHF Study Subanalysis

Núñez, J., Bayés-Genís, A., Revuelta-López, E., Ter Maaten, J. M., Miñana, G., Barallat, J., Cserkóová, A., Bodi, V., Fernández-Cisnal, A., Núñez, E., Sanchis, J., Lang, C., Ng, L. L., Metra, M. & Voors, A. A., May 2020, In : JACC: Heart Failure. 8, 5, p. 386-397 12 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Cohort Profile: Genetics of Diabetes Audit and Research in Tayside Scotland (GoDARTS)

Hébert, H. L., Shepherd, B., Milburn, K., Veluchamy, A., Meng, W., Carr, F., Donnelly, L. A., Tavendale, R., Leese, G., Colhoun, H. M., Dow, E., Morris, A. D., Doney, A. S., Lang, C. C., Pearson, E. R., Smith, B. H. & Palmer, C. N. A., 1 Apr 2018, In : International Journal of Epidemiology. 47, 2, p. 380-381j 12 p.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
219 Downloads (Pure)

Comparing biomarker profiles of patients with heart failure: atrial fibrillation vs. sinus rhythm and reduced vs. preserved ejection fraction

Santema, B. T., Kloosterman, M., Van Gelder, I. C., Mordi, I., Lang, C., Lam, C. S. P., Anker, S. D., Cleland, J. G. F., Dickstein, K., Filippatos, G. S., van der Harst, P., Hillege, H. L., ter Maaten, J. M., Metra, M., Ng, L. L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zwinderman, A. H., Zannad, F. & 4 others, Damman, K., van der Meer, P., Rienstra, M. & Voors, A. A., 14 Nov 2018, In : European Heart Journal. 39, 43, p. 3867-3875 9 p.

Research output: Contribution to journalArticle

Open Access
File
19 Citations (Scopus)
69 Downloads (Pure)

Comparison of exercise testing and CMR measured myocardial perfusion reserve for predicting outcome in asymptomatic aortic stenosis: the PRognostic Importance of MIcrovascular Dysfunction in Aortic Stenosis (PRIMID AS) study

Singh, A., Greenwood, J. P., Berry, C., Dawson, D. K., Hogrefe, K., Kelly, D. J., Dhakshinamurthy, V., Lang, C. C., Khoo, J. P., Sprigings, D., Steeds, R. P., Jerosch-Herold, M., Neubauer, S., Prendergast, B., Williams, B., Zhang, R., Hudson, I., Squire, I. B., Ford, I., Samani, N. J. & 1 others, McCann, G. P., 21 Apr 2017, In : European Heart Journal. 38, 16, p. 1222-1229 8 p.

Research output: Contribution to journalArticle

Open Access
File
32 Citations (Scopus)
142 Downloads (Pure)

Concentric vs. eccentric remodelling in heart failure with reduced ejection fraction: clinical characteristics, pathophysiology and response to treatment

Nauta, J. F., Hummel, Y. M., Tromp, J., Ouwerkerk, W., van der Meer, P., Jin, X., Lam, C. S. P., Bax, J. J., Metra, M., Samani, N. J., Ponikowski, P., Dickstein, K., Anker, S. D., Lang, C., Ng, L. L., Zannad, F., Filippatos, G. S., van Veldhuisen, D. J., van Melle, J. P. & Voors, A. A., 11 Nov 2019, In : European Journal of Heart Failure. 9 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
67 Downloads (Pure)

Coronary angiography in worsening heart failure: determinants, findings, and prognostic implications

Ferreira, J. P., Rossignol, P., Demissei, B., Sharma, A., Girerd, N., Anker, S. D., Cleland, J. G. F., Dickstein, K., Filippatos, G. S., Hillege, H. L., Lang, C. C., Metra, M., Ng, L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zwinderman, A. H., Voors, A. A. & Zannad, F., 1 Apr 2018, In : Heart. 104, 7, p. 606-613 8 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
401 Downloads (Pure)

Dapagliflozin Versus Placebo on Left Ventricular Remodeling in Patients With Diabetes and Heart Failure: The REFORM Trial

Singh, J. S. S., Mordi, I. R., Vickneson, K., Fathi, A., Donnan, P. T., Mohan, M., Choy, A. M. J., Gandy, S., George, J., Khan, F., Pearson, E. R., Houston, J. G., Struthers, A. D. & Lang, C. C., 1 Jun 2020, In : Diabetes Care. 43, 6, p. 1356-1359 4 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
62 Downloads (Pure)

Determinants and clinical outcome of uptitration of ACE-inhibitor and beta-blocker in patients with heart failure: a prospective European study

Ouwerkerk, W., Voors, A. A., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., van der Harst, P., Hillege, H. L., Lang, C. C., ter Maaten, J. M., Ng, L. L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Metra, M. & Zwinderman, A. H., 21 Jun 2017, In : European Heart Journal. 38, 24, p. 1883-1890b 10 p.

Research output: Contribution to journalArticle

Open Access
File
121 Citations (Scopus)
112 Downloads (Pure)

Development and validation of multivariable models to predict mortality and hospitalization in patients with heart failure

Voors, A. A., Ouwerkerk, W., Zannad, F., van Veldhuisen, D. J., Samani, N. J., Ponikowski, P., Ng, L., Metra, M., ter Maaten, J. M., Lang, C., Hillege, H. L., van der Harst, P., Filippatos, G. S., Dickstein, K., Cleland, J. G. F., Anker, S. D. & Zwinderman, K., 9 May 2017, In : European Journal of Heart Failure. 19, 5, p. 627-634 8 p.

Research output: Contribution to journalArticle

Open Access
File
69 Citations (Scopus)
140 Downloads (Pure)

Distinct Pathological Pathways in Patients with Heart Failure and Diabetes

Tromp, J., Voors, A. A., Sharma, A., Ferreira, J. P., Ouwerkerk, W., Hillege, H. L., Arevalo Gomez, K., Dickstein, K., Anker, S. D., Metra, M., Lang, C., Ng, L. L., van der Harst, P., van Veldhuisen, D. J., van der Meer, P., Lam, C. S. P., Zannad, F. & Sama, I. E., Mar 2020, In : JACC: Heart Failure. 8, 3, p. 234-242 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
Open Access
File
8 Citations (Scopus)
203 Downloads (Pure)

Effects of combined renin-angiotensin-aldosterone system inhibitor and beta-blocker treatment on outcomes in heart failure with reduced ejection fraction: insights from BIOSTAT-CHF and ASIAN-HF registries

Ouwerkerk, W., Teng, T-H. K., Tromp, J., Tay, W. T., Cleland, J. G., van Veldhuisen, D. J., Dickstein, K., Ng, L. L., Lang, C. C., Anker, S. D., Zannad, F., Hung, C-L., Sawhney, J. P. S., Naik, A., Shimizu, W., Hagiwara, N., Wander, G. S., Anand, I., Richards, A. M., Voors, A. A. & 1 others, Lam, C. S. P., 25 Jun 2020, In : European Journal of Heart Failure. 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Effects of the coronary artery disease associated LPA and 9p21 loci on risk of aortic valve stenosis

Trenkwalder, T., Nelson, C. P., Musameh, M. D., Mordi, I. R., Kessler, T., Pellegrini, C., Debiec, R., Rheude, T., Lazovic, V., Zeng, L., Martinsson, A., Gustav Smith, J., Gådin, J. R., Franco-Cereceda, A., Eriksson, P., Nielsen, J. B., Graham, S. E., Willer, C. J., Hveem, K., Kastrati, A. & 9 others, Braund, P. S., Palmer, C. N. A., Aracil, A., Husser, O., Koenig, W., Schunkert, H., Lang, C. C., Hengstenberg, C. & Samani, N. J., 1 Feb 2019, In : International Journal of Cardiology. 276, p. 212-217 6 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
121 Downloads (Pure)

Epicardial Adipose Tissue Is Related to Arterial Stiffness and Inflammation in Patients with Cardiovascular Disease and Type 2 Diabetes

Al-Talabany, S., Mordi, I., Houston, J. G., Colhoun, H. M., Weir-McCall, J. R., Matthew, S. Z., Looker, H. C., Levin, D., Belch, J. J. F., Dove, F., Khan, F. & Lang, C. C., 13 Feb 2018, In : BMC Cardiovascular Disorders. 18, p. 1-8 8 p., 31.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
155 Downloads (Pure)

Epicardial Adipose Tissue is Related to Arterial Stiffness in Patients with Cardio-metabolic Disease

Al-Talabany, S., Khan, F., Houston, G., Colhoun, H., Weir-Mccall, J., Leven, D., Dove, F., Cassidy, D., Looker, H. & Lang, C., 5 Apr 2016, In : Journal of the American College of Cardiology. 67, 13, Supplement 5, p. 1832 1 p., 1263-258.

Research output: Contribution to journalArticle

Fibroblast growth factor 23 is related to profiles indicating volume overload, poor therapy optimization and prognosis in patients with new-onset and worsening heart failure

Ter Maaten, J. M., Voors, A. A., Damman, K., van der Meer, P., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., van der Harst, P., Hillege, H. L., Lang, C. C., Metra, M., Navis, G., Ng, L., Ouwerkerk, W., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Zwinderman, A. H. & 1 others, de Borst, M. H., 15 Feb 2018, In : International Journal of Cardiology. 253, p. 84-90 7 p.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
173 Downloads (Pure)

Genetic associations with plasma ACE2 concentration – potential relevance to Covid-19 risk

Nelson, C. P., Sama, I. E., Codd, V., Webb, T. R., Ye, S., Lang, C. C., Voors, A. A., Ng, L. L. & Samani, N. J., 7 Jul 2020, In : Circulation.

Research output: Contribution to journalArticle

Open Access

Genetic Risk and Atrial Fibrillation in Patients with Heart Failure

Kloosterman, M., Santema, B. T., Roselli, C., Nelson, C. P., Koekemoer, A., Romaine, S. P. R., Van Gelder, I. C., Lam, C. S. P., Artola, V. A., Lang, C., Ng, L. L., Metra, M., Anker, S. D., Filippatos, G. S., Dickstein, K., Ponikowski, P., van der Harst, P., Meer, P. V. D., Van Veldhuisen, D. J., Benjamin, E. J. & 3 others, Voors, A. A., Samani, N. J. & Rienstra, M., 27 Mar 2020, In : European Journal of Heart Failure. 22, 3, p. 519-527 9 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
48 Downloads (Pure)
Open Access
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10 Downloads (Pure)

Genetic variation in Kruppel like factor 15 is associated with left ventricular hypertrophy in patients with type 2 diabetes: discovery and replication cohorts

Patel, S. K., Wai, B., Lang, C. C., Levin, D., Palmer, C. N. A., Parry, H. M., Velkoska, E., Harrap, S. B., Srivastava, P. M. & Burrell, L. M., Apr 2017, In : EBioMedicine. 18, p. 171-178 8 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
71 Downloads (Pure)

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

Regeneron Genetics Center, Shah, S., Henry, A., Roselli, C., Lin, H., Sveinbjörnsson, G., Fatemifar, G., Hedman, Å. K., Wilk, J. B., Morley, M. P., Chaffin, M. D., Helgadottir, A., Verweij, N., Dehghan, A., Almgren, P., Andersson, C., Aragam, K. G., Ärnlöv, J., Backman, J. D., Biggs, M. L. & 32 others, Bloom, H. L., Brandimarto, J., Brown, M. R., Buckbinder, L., Carey, D. J., Chasman, D. I., Chen, X., Chen, X., Chung, J., Chutkow, W., Cook, J. P., Delgado, G. E., Denaxas, S., Doney, A. S., Dörr, M., Dudley, S. C., Dunn, M. E., Engström, G., Esko, T., Felix, S. B., Finan, C., Ford, I., Mordi, I. R., Morris, A. D., Morris, A. P., Palmer, C. N. A., Parry, H. M., Smith, N. L., Veluchamy, A., McMurray, J. J. V., Lang, C. C. & Lumbers, R. T., 9 Jan 2020, In : Nature Communications. 11, 12 p., 163.

Research output: Contribution to journalArticle

Open Access
File
17 Citations (Scopus)
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Genome-wide association study of angioedema induced by angiotensin-converting enzyme inhibitor and angiotensin receptor blocker treatment

Rasmussen, E. R., Hallberg, P., Baranova, E. V., Eriksson, N., Karawajczyk, M., Johansson, C., Cavalli, M., Maroteau, C., Veluchamy, A., Islander, G., Hugosson, S., Terreehorst, I., Asselbergs, F. W., Norling, P., Johansson, H-E., Kohnke, H., Syvänen, A-C., Siddiqui, M. K., Lang, C., Magnusson, P. K. E. & 8 others, Yue, Q-Y., Wadelius, C., von Buchwald, C., Bygum, A., Alfirevic, A., Maitland-van der Zee, A. H., Palmer, C. N. A. & Wadelius, M., 21 Feb 2020, In : Pharmacogenomics Journal. 14 p.

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Geographical differences in heart failure characteristics and treatment across Europe: results from the BIOSTAT-CHF study

Lombardi, C. M., Ferreira, J. P., Carubelli, V., Anker, S. D., Cleland, J. G., Dickstein, K., Filippatos, G., Lang, C. C., Ng, L. L., Ponikowski, P., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Voors, A. & Metra, M., 1 Aug 2020, In : Clinical Research in Cardiology . 109, 8, p. 967-977 11 p.

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Heart failure etiologies and clinical factors precipitating for worsening heart failure: Findings from BIOSTAT-CHF

Kobayashi, M., Voors, A. A., Girerd, N., Billotte, M., Anker, S. D., Cleland, J. G., Lang, C. C., Ng, L. L., van Veldhuisen, D. J., Dickstein, K., Metra, M., Duarte, K., Rossignol, P., Zannad, F. & Ferreira, J. P., 8 Nov 2019, In : European Journal of Internal Medicine. 8 p.

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Heart failure in the outpatient versus inpatient setting: findings from the BIOSTAT-CHF study

Ferreira, J. P., Metra, M., Mordi, I., Gregson, J., ter Maaten, J., Tromp, J., Anker, S. D., Dickstein, K., Hillege, H. L., Ng, L. L., van Veldhuisen, D. J., Lang, C. C., Voors, A. A. & Zannad, F., 1 Jan 2019, In : European Journal of Heart Failure. 21, 1, p. 112-120 9 p.

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Heart failure treatment up‐titration and outcome and age: an analysis of BIOSTAT‐CHF

Mordi, I. R., Ouwerkerk, W., Anker, S. D., Cleland, J. G., Dickstein, K., Metra, M., Ng, L. L., Samani, N. J., van Veldhuisen, D. J., Zannad, F., Voors, A. A. & Lang, C. C., 25 Mar 2020, In : European Journal of Heart Failure. 10 p.

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Higher doses of loop diuretics limit uptitration of angiotensin converting enzyme inhibitors in patients with heart failure and reduced ejection fraction

ter Maaten, J. M., Martens, P., Damman, K., Dickstein, K., Ponikowski, P., Lang, C., Ng, L. L., Anker, S. D., Samani, N. J., Filippatos, G. S., Cleland, J. G. F., Zannad, F., Hillege, H. L., van Veldhuisen, D. J., Metra, M., Voors, A. A. & Mullens, W., 1 Aug 2020, In : Clinical Research in Cardiology . 109, 8, p. 1048-1059 12 p.

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Identifying optimal doses of heart failure medications in men compared with women: a prospective, observational cohort study

Santema, B. T., Ouwerkerk, W., Tromp, J., Sama, I. E., Ravera, A., Regitz-Zagrosek, V., Hillege, H., Samani, N. J., Zannad, F., Dickstein, K., Lang, C., Cleland, J. G., ter Maaten, J. M., Metra, M., Anker, S. D., van der Harst, P., Ng, L. L., Meer, P. V. D., van Veldhuisen, D. J., Meyer, S. & 1 others, Voors, A. A., 5 Oct 2019, In : Lancet. 394, 10205, p. 1254-1263 10 p.

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Identifying Pathophysiological Mechanisms in Heart Failure With Reduced Versus Preserved Ejection Fraction

Tromp, J., Westenbrink, D., Ouwerkerk, W., van Veldhuisen, D. J., Samani, N. J., Ponikowski, P., Metra, M., Anker, S. D., Cleland, J. G. F., Dickstein, K., Filippatos, G. S., van der Harst, P., Lang, C., Ng, L. L., Zannad, F., Zwinderman, A. H., Hillege, H. L., van der Meer, P. & Voors, A. A., 4 Sep 2018, In : Journal of the American College of Cardiology. 72, 10, p. 1081-1090 10 p.

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Iron deficiency in worsening heart failure is associated with reduced estimated protein intake, fluid retention, inflammation and antiplatelet use

van der Wal, H. H., Beverborg, N. G., Dickstein, K., Anker, S. D., Lang, C. C., Ng, L. L., van Veldhuisen, D. J., Voors, A. A. & van der Meer, P., 21 Nov 2019, In : European Heart Journal. 40, 44, p. 3616-3625 10 p.

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Mean HbA1c and mortality in diabetic individuals with heart failure: a population cohort study

Elder, D. H. J., Singh, J. S. S., Levin, D., Donnelly, L. A., Choy, A-M. J., George, J., Struthers, A. D., Doney, A. S. F. & Lang, C. C., Jan 2016, In : European Journal of Heart Failure. 18, 1, p. 94-102 9 p.

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