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Article
Cross-talk between the p38 alpha and JNK MAPK Pathways Mediated by MAP Kinase Phosphatase-1 Determines Cellular Sensitivity to UV Radiation
Staples, C. J., Owens, D. M., Maier, J. V., Cato, A. C. B. & Keyse, S. M., 20 Aug 2010, In: Journal of Biological Chemistry. 285, 34, p. 25928-25940 13 p.Research output: Contribution to journal › Article › peer-review
53 Citations (Scopus) -
Cross-tissue eQTL enrichment of associations in schizophrenia.
Bettella, F., Brown, A. A., Smeland, O. B., Wang, Y., Witoelar, A., Buil Demur, A. A., Thompson, W. K., Zuber, V., Dale, A. M., Djurovic, S. & Andreassen, O. A., 6 Sep 2018, In: PLoS ONE. 13, 9, p. 1-17 17 p., e0202812.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)120 Downloads (Pure) -
Cross-tolerance to biotic and abiotic stresses in plants: a focus on resistance to aphid infestation
Foyer, C. H., Rasool, B., Davey, J. W. & Hancock, R. D., Mar 2016, In: Journal of Experimental Botany. 67, 7, p. 2025-2037 13 p.Research output: Contribution to journal › Article › peer-review
67 Citations (Scopus) -
Cross-View Self-Similarity Using Shared Dictionary Learning for Cervical Cancer Staging
Bnouni, N., Rekik, I., Rhim, M. S. & Amara, N. E. B., 5 Mar 2019, In: IEEE Access. 7, p. 30079-30088 10 p., 8658198.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)137 Downloads (Pure) -
Crucial leadership features in the new global era
Fragouli, E., Dec 2009, In: International Journal of Business Management, Economics and Information Technology. 1, 2, p. 107-123 17 p.Research output: Contribution to journal › Article › peer-review
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Cruciate Retaining compared with Posterior Stabilised Nexgen total knee arthroplasty: results at 10 years in a matched cohort
Mayne, A. I. W., Harshavardhan, H. P., Johnston, L. R., Wang, W. & Jariwala, A., Nov 2017, In: Annals of the Royal College of Surgeons of England. 99, 8, p. 602-606 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)143 Downloads (Pure) -
Crumbs2 mediates ventricular layer remodelling to form the spinal cord central canal
Tait, C., Chinnaiya, K., Manning, E., Murtaza, M., Ashton, J-P., Furley, N., Hill, C. J., Alves, C. H., Wijnholds, J., Erdmann, K. S., Furley, A., Rashbass, P., Das, R. M., Storey, K. G. & Placzek, M., 9 Mar 2020, In: PLoS Biology. 18, 3, 28 p., e3000470.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)31 Downloads (Pure) -
Crumbs 3b promotes tight junctions in an ezrin-dependent manner in mammalian cells
Tilston-Lünel, A. M., Haley, K. E., Schlecht, N. F., Wang, Y., Chatterton, A. L. D., Moleirinho, S., Watson, A., Hundal, H. S., Prystowsky, M. B., Gunn-Moore, F. J. & Reynolds, P. A., Oct 2016, In: Journal of Molecular Cell Biology. 8, 5, p. 439-455 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)392 Downloads (Pure) -
Crushing of particles in idealised granular assemblies
Russell, A. R., Muir Wood, D. & Kikumoto, M., 1 Aug 2009, In: Journal of the Mechanics and Physics of Solids. 57, 8, p. 1293-1313 21 p.Research output: Contribution to journal › Article › peer-review
57 Citations (Scopus) -
Crushing of particles in idealised granular assemblies
Russell, A. R., Muir Wood, D. & Kikumoto, M., Aug 2009, In: Journal of the Mechanics and Physics of Solids. 57, 8, p. 1293-1313 21 p.Research output: Contribution to journal › Article › peer-review
57 Citations (Scopus) -
Cryo-electron microscopy of GDP-tubulin rings
Nicholson, W. V., Lee, M., Downing, K. H. & Nogales, E., Jun 1999, In: Cell Biochemistry and Biophysics. 31, 2, p. 175-183 9 p.Research output: Contribution to journal › Article › peer-review
27 Citations (Scopus) -
Cryogenic surface resistance of copper: Investigation of the impact of surface treatments for secondary electron yield reduction
Calatroni, S., Arzeo, M., Aull, S., Himmerlich, M., Costa Pinto, P., Vollenberg, W., Di Girolamo, B., Cruikshank, P., Chiggiato, P., Bajek, D., Wackerow, S. & Abdolvand, A., 20 Jun 2019, In: Physical Review Special Topics - Accelerators and Beams. 22, 6, 9 p., 063101.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)142 Downloads (Pure) -
Cryptogenic stroke as initial manifestation of CNS vasculitis: demonstration of vessel wall enhancement on 1.5T MRI using volumetric T1 TSE sequence
Badran, K., Kanodia, A. K., Abdelsadg, M. & Galea, J., 15 Mar 2018, In: BMJ Case Reports. 2018, 3 p., bcr-2018-224352.Research output: Contribution to journal › Article › peer-review
Open Access -
Crystal and Molecular Structure and DFT Calculations of the Steroidal Oxime 6E-Hydroximino-androst-4-ene-3,17-dione (C19H25NO3) a Molecule with Antiproliferative Activity
Palmer, R. A., Lisgarten, D. R., Cockcroft, J. K., Lisgarten, J. N., Talbert, R., Dines, T., Bansal, R., Acharya, P. C. & Suryan, A., 9 Nov 2018, In: Journal of Chemical Crystallography. 9 p.Research output: Contribution to journal › Article › peer-review
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Crystallographic analysis of Neisseria meningitidis PorB extracellular loops potentially implicated in TLR2 recognition
Kattner, C., Toussi, D., Zaucha, J., Wetzler, L. M., Rüppel, N., Zachariae, U., Massari, P. & Tanabe, M., Mar 2014, In: Journal of Structural Biology. 185, 3, p. 440-447 8 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
Crystallographic study of inhibitors of tRNA-guanine transglycosylase suggests a new structure-based pharmacophore for virtual screening
Brenk, R., Meyer, E. A., Reuter, K., Stubbs, M. T., Garcia, G. A., Diederich, F. & Klebe, G., Apr 2004, In: Journal of Molecular Biology. 338, 1, p. 55-75 21 p.Research output: Contribution to journal › Article › peer-review
31 Citations (Scopus) -
Crystals on the cover 2015
Einspahr, H., Weiss, M. S. & Hunter, W. N., Jan 2015, In: Acta Crystallographica Section F: Structural Biology Communications. F71, 1, p. 1-2 2 p.Research output: Contribution to journal › Article › peer-review
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Crystal structure and binding properties of the Serratia marcescens chitin-binding protein CBP21
Vaaje-Kolstad, G., Houston, D. R., Riemen, A. H. K., Eijsink, V. G. H. & van Aalten, D. M. F., 25 Mar 2005, In: Journal of Biological Chemistry. 280, 12, p. 11313-11319 7 p.Research output: Contribution to journal › Article › peer-review
196 Citations (Scopus) -
Crystal structure and functional mechanism of a human antimicrobial membrane channel
Song, C., Weichbrodt, C., Salnikov, E. S., Dynowski, M., Forsberg, B. O., Bechinger, B., Steinem, C., De Groot, B. L., Zachariae, U. & Zeth, K., 19 Mar 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 12, p. 4586-4591 6 p.Research output: Contribution to journal › Article › peer-review
Open Access80 Citations (Scopus) -
Crystal structure and ligand-induced folding of the SAM/SAH riboswitch
Huang, L., Liao, T-W., Wang, J., Ha, T. & Lilley, D., 27 Jul 2020, In: Nucleic Acids Research. 48, 13, p. 7545-7556 12 p.Research output: Contribution to journal › Article › peer-review
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Crystal structure and mechanistic investigation of the twister ribozyme
Liu, Y., Wilson, T. J., McPhee, S. A. & Lilley, D. M. J., Sep 2014, In: Nature Chemical Biology. 10, 9, p. 739-744 6 p.Research output: Contribution to journal › Article › peer-review
74 Citations (Scopus) -
Crystal structure of activated ModE reveals conformational changes involving both oxyanion and DNA-binding domains
Schuttelkopf, A. W., Boxer, D. H. & Hunter, W. N., 2003, In: Journal of Molecular Biology. 326, 3, p. 761-767 7 p.Research output: Contribution to journal › Article › peer-review
30 Citations (Scopus) -
Crystal Structure of a Eukaryotic GEN1 Resolving Enzyme Bound to DNA
Liu, Y., Freeman, A. D. J., Déclais, A. C., Wilson, T. J., Gartner, A. & Lilley, D. M. J., 22 Dec 2015, In: Cell Reports. 13, 11, p. 2565-2575 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile28 Citations (Scopus)152 Downloads (Pure) -
Crystal structure of an HD-GYP domain cyclic-di-GMP phosphodiesterase reveals an enzyme with a novel trinuclear catalytic iron centre
Bellini, D., Caly, D. L., McCarthy, Y., Bumann, M., An, S-Q., Dow, J. M., Ryan, R. P. & Walsh, M. A., Jan 2014, In: Molecular Microbiology. 91, 1, p. 26-38 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile53 Citations (Scopus)153 Downloads (Pure) -
Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes
Roach, P. L., Clifton, I. J., Fülöp, V., Harlos, K., Barton, G. J., Hajdu, J., Andersson, I., Schofield, C. & Baldwin, J. E., 22 Jun 1995, In: Nature. 375, 6533, p. 700-704 5 p.Research output: Contribution to journal › Article › peer-review
359 Citations (Scopus) -
Crystal structure of Leishmania major ADP-ribosylation factor-like 1 and a classification of related GTPase family members in this Kinetoplastid
Fleming, J. R., Dawson, A. & Hunter, W. N., Dec 2010, In: Molecular and Biochemical Parasitology. 174, 2, p. 141-144 4 p.Research output: Contribution to journal › Article › peer-review
4 Citations (Scopus) -
Crystal structure of MO25 in complex with the C terminus of the pseudo kinase STE20-related adaptor
Milburn, C. C., Boudeau, J., Deak, M., Alessi, D. R. & van Aalten, D. M. F., 2004, In: Nature Structural & Molecular Biology. 11, 2, p. 193-200 8 p.Research output: Contribution to journal › Article › peer-review
57 Citations (Scopus) -
Crystal structure of quinol-dependent nitric oxide reductase from Geobacillus stearothermophilus
Matsumoto, Y., Tosha, T., Pisliakov, A. V., Hino, T., Sugimoto, H., Nagano, S., Sugita, Y. & Shiro, Y., Feb 2012, In: Nature Structural & Molecular Biology. 19, 2, p. 238-245 8 p.Research output: Contribution to journal › Article › peer-review
79 Citations (Scopus) -
Crystal structure of RlmM, the 2'O-ribose methyltransferase for C2498 of Escherichia coli 23S rRNA
Punekar, A. S., Shepherd, T. R., Liljeruhm, J., Forster, A. C. & Selmer, M., 1 Nov 2012, In: Nucleic Acids Research. 40, 20, p. 10507-10520 14 p.Research output: Contribution to journal › Article › peer-review
7 Citations (Scopus) -
Crystal structure of the acid-induced arginine decarboxylase from Escherichia coli: reversible decamer assembly controls enzyme activity
Andrell, J., Hicks, M. G., Palmer, T., Carpenter, E. P., Iwata, S. & Maher, M. J., 2009, In: Biochemistry. 48, 18, p. 3915-3927 13 p.Research output: Contribution to journal › Article › peer-review
38 Citations (Scopus) -
Crystal structure of the C-terminal domain of tubulin-binding cofactor C from Leishmania major
Barrack, K. L., Fyfe, P. K., Finney, A. J. & Hunter, W. N., May 2015, In: Molecular and Biochemical Parasitology. 201, 1, p. 26-30 5 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
Crystal Structure of the Cul2-Rbx1-EloBC-VHL Ubiquitin Ligase Complex
Cardote, T. A. F., Gadd, M. S. & Ciulli, A., 6 Jun 2017, In: Structure. 25, 6, p. 901-911.e3 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile33 Citations (Scopus)174 Downloads (Pure) -
Crystal structure of the Holliday junction resolving enzyme T7 endonuclease I.
Hadden, JM., Convery, MA., Déclais, AC., Lilley, DM. & Phillips, S. E. V., Jan 2001, In: Nature Structural and Molecular Biology. 8, 1, p. 62-67Research output: Contribution to journal › Article › peer-review
79 Citations (Scopus) -
Crystal structure of the MAPK phosphatase Pyst1 catalytic domain and implications for regulated activation
Stewart, A. E., Dowd, S., Keyse, S. M. & McDonald, N. Q., Feb 1999, In: Nature Structural & Molecular Biology. 6, 2, p. 174-81 8 p.Research output: Contribution to journal › Article › peer-review
139 Citations (Scopus) -
Crystal structure of the molybdenum cofactor biosynthesis protein MobA from Escherichia coli at near-atomic resolution
Stevenson, C. E. M., Sargent, F., Buchanan, G., Palmer, T. & Lawson, D. M., 15 Nov 2000, In: Structure. 8, 11, p. 1115-1125 11 p.Research output: Contribution to journal › Article › peer-review
36 Citations (Scopus) -
Crystal structure of the O2-tolerant membrane-bound hydrogenase 1 from Escherichia coli in complex with its cognate cytochrome b
Volbeda, A., Darnault, C., Parkin, A., Sargent, F., Armstrong, F. A. & Fontecilla-Camps, J. C., Jan 2013, In: Structure. 21, 1, p. 184-90 7 p.Research output: Contribution to journal › Article › peer-review
65 Citations (Scopus) -
Crystal structure of the PEG-bound SH3 domain of myosin IB from Entamoeba histolytica reveals its mode of ligand recognition
Gautam, G., Rehman, S. A. A., Pandey, P. & Gourinath, S., 1 Aug 2017, In: Acta Crystallographica Section D: Structural Biology. 73, 8, p. 672-682 11 p.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
Crystal structure of the PTPL1/FAP-1 human tyrosine phosphatase mutated in colorectal cancer: evidence for a second phosphotyrosine substrate recognition pocket
Villa, F., Deak, M., Bloomberg, G. B., Alessi, D. R. & Van Aalten, D. M. F., 2005, In: Journal of Biological Chemistry. 280, 9, p. 8180-8187 8 p.Research output: Contribution to journal › Article › peer-review
32 Citations (Scopus) -
Crystal structure of the SPOC domain of the Arabidopsis flowering regulator FPA
Zhang, Y., Rataj, K., Simpson, G. G. & Tong, L., 11 Aug 2016, In: PLoS ONE. 11, 8, 13 p., e0160694.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)225 Downloads (Pure) -
Crystal structure of the Varkud satellite ribozyme
Suslov, N. B., Dasgupta, S., Huang, H., Fuller, J. R., Lilley, D. M. J., Rice, P. A. & Piccirilli, J. A., Nov 2015, In: Nature Chemical Biology. 11, p. 840-846 7 p.Research output: Contribution to journal › Article › peer-review
55 Citations (Scopus) -
Crystal structure of the WD40 domain dimer of LRRK2
Zhang, P., Fan, Y., Ru, H., Wang, L., Magupalli, V. G., Taylor, S. S., Alessi, D. R. & Wu, H., 29 Jan 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 5, p. 1579-1584 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)161 Downloads (Pure) -
Crystal structures of a bacterial 6-phosphogluconate dehydrogenase reveal aspects of specificity, mechanism and mode of inhibition by analogues of high-energy reaction intermediates
Sundaramoorthy, R., Iulek, J., Barrett, M. P., Bidet, O., Ruda, G. F., Gilbert, I. H. & Hunter, W. N., Jan 2007, In: FEBS Journal. 274, 1, p. 275-286 12 p.Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus) -
Crystal structures of Burkholderia cenocepacia dihydropteroate synthase in the apo-form and complexed with the product 7,8-dihydropteroate
Morgan, R. E., Batot, G. O., Dement, J. M., Rao, V. A., Eadsforth, T. C. & Hunter, W. N., 9 May 2011, In: BMC Structural Biology. 11, p. - 9 p., 21.Research output: Contribution to journal › Article › peer-review
11 Citations (Scopus) -
Crystal structures of cyanine fluorophores stacked onto the end of double-stranded RNA
Liu, Y. & Lilley, D. M. J., 5 Dec 2017, In: Biophysical Journal. 113, 11, p. 2236-2343 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)193 Downloads (Pure) -
Crystal structures of IspF from Plasmodium falciparum and Burkholderia cenocepacia: comparisons inform antimicrobial drug target assessment
O'Rourke, P. E. F., Kalinowska-Tłuścik, J., Fyfe, P. K., Dawson, A. & Hunter, W. N., 10 Jan 2014, In: BMC Structural Biology. 14, 12 p., 1.Research output: Contribution to journal › Article › peer-review
Open Access12 Citations (Scopus) -
Crystal structures of penicillin-binding protein 3 from Pseudomonas aeruginosa: comparison of native and antibiotic-bound forms
Sainsbury, S., Bird, L., Rao, V., Shepherd, S. M., Stuart, D. I., Hunter, W. N., Owens, R. J. & Ren, J., 7 Jan 2011, In: Journal of Molecular Biology. 405, 1, p. 173-184 12 p.Research output: Contribution to journal › Article › peer-review
50 Citations (Scopus) -
Crystal structures of Toxoplasma gondii pterin-4a-carbinolamine dehydratase and comparisons with mammalian and parasite orthologues
Cameron, S., Fyffe, S. A., Goldie, S. & Hunter, W. N., Apr 2008, In: Molecular and Biochemical Parasitology. 158, 2, p. 131-138 8 p.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
Crystal structures of Trypanosoma brucei and Staphylococcus aureus mevalonate diphosphate decarboxylase inform on the determinants of specificity and reactivity
Byres, E., Alphey, M. S., Smith, T. K. & Hunter, W. N., 10 Aug 2007, In: Journal of Molecular Biology. 371, 2, p. 540-553 14 p.Research output: Contribution to journal › Article › peer-review
31 Citations (Scopus) -
Crystal structures reveal that the reaction mechanism of imidazoleglycerol-phosphate dehydratase is controlled by switching Mn(II) coordination
Bisson, C., Britton, K. L., Sedelnikova, S. E., Rodgers, H. F., Eadsforth, T. C., Viner, R. C., Hawkes, T. R., Baker, P. J. & Rice, D. W., 7 Jul 2015, In: Structure. 23, 7, p. 1236-1245 10 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
Crystal 'unengineering': reducing the crystallisability of sulfolobus solfataricus Hjc
Middleton, C. L., Parker, J. L., Knott, G. J., White, M. F. & Bond, C. S., 18 Aug 2014, In: Australian Journal of Chemistry. 67, 12, p. 1818-1823 6 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus)