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  Inhibition of proton-translocating transhydrogenase from photosynthetic bacteria by N,N′-dicyclohexylcarbodiimide

  Palmer, T., Williams, R., Cotton, N. P. J., Thomas, C. M. & Jackson, J. B., 1 Feb 1993, In: European Journal of Biochemistry. 211, 3, p. 663-669 7 p.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• Inhibition of Rho at different stages of thymocyte development gives different perspectives on Rho function

  Cleverley, S., Henning, S. & Cantrell, D., 17 Jun 1999, In: Current Biology. 9, 12, p. 657-660 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • thymocytes
  • Thymocytes
  • Transferases
  • T-cells
  • T-Cell Antigen Receptor
  33 Citations (Scopus)

• Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs

  Rousseau, S., Morrice, N., Peggie, M., Campbell, D. G., Gaestel, M. & Cohen, P., Dec 2002, In: The EMBO Journal. 21, 23, p. 6505-6514 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Mitogen-Activated Protein Kinase 14
  • Phosphorylation
  • Heterogeneous-Nuclear Ribonucleoproteins
  • Macrophages
  • Lipopolysaccharides
  176 Citations (Scopus)

• Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages

  Darling, N. J., Toth, R., Arthur, J. S. C. & Clark, K., 3 Feb 2017, In: Biochemical Journal. 474, 4, p. 521-537 17 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Macrophages
  • Anti-Inflammatory Agents
  • Phenotype
  • Salts
  • Phosphotransferases
  22 Citations (Scopus)

  167 Downloads (Pure)

• Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity

  Liu, J., Albers, M. W., Wandless, T. J., Luan, S., Alberg, D. G., Belshaw, P. J., Cohen, P. ., MacKintosh, C., Klee, C. B. & Schreiber, S. L., 1992, In: Biochemistry. 31, 16, p. 3896-3901 6 p.

  Research output: Contribution to journal › Article › peer-review
  480 Citations (Scopus)

• Inhibition of thalamic excitability by 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine-3-ol: a selective role for delta-GABA(A) receptors

  Herd, M. B., Foister, N., Chandra, D., Peden, D. R., Homanics, G. E., Brown, V. J., Balfour, D. J. K., Lambert, J. J. & Belelli, D., Mar 2009, In: European Journal of Neuroscience. 29, 6, p. 1177-1187 11 p.

  Research output: Contribution to journal › Article › peer-review
  57 Citations (Scopus)

• Inhibition of the ERCC1-XPF structure-specific endonuclease to overcome cancer chemoresistance

  McNeil, E. M., Astell, K. R., Ritchie, A. M., Shave, S., Houston, D. R., Bakrania, P., Jones, H. M., Khurana, P., Wallace, C., Chapman, T., Wear, M. A., Walkinshaw, M. D., Saxty, B. & Melton, D. W., 1 Jul 2015, In: DNA Repair. 31, p. 19-28 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Endonucleases
  • DNA Repair
  • Repair
  • Cisplatin
  • Nucleotides
  43 Citations (Scopus)

• Inhibition of the G₂ DNA Damage Checkpoint and of Protein Kinases Chk1 and Chk2 by the Marine Sponge Alkaloid Debromohymenialdisine

  Curman, D., Cinel, B., Williams, D. E., Rundle, N., Block, W. D., Goodarzi, A. A., Hutchins, J. R., Clarke, P. R., Zhou, B. B., Lees-Miller, S. P., Andersen, R. J. & Roberge, M., 25 Jan 2001, In: Journal of Biological Chemistry. 276, 21, p. 17914-17919 6 p.

  Research output: Contribution to journal › Article › peer-review

  • debromohymenialdisine
  • Checkpoint Kinase 2
  • Checkpoint Kinase 1
  • Porifera
  • Alkaloids
  117 Citations (Scopus)

• Inhibition of the GlcNAc transferase of the glycosylphosphatidylinositol anchor biosynthesis in African trypanosomes

  Milne, K. G., Ferguson, M. & Masterson, W. J., Sep 1992, In: European Journal of Biochemistry. 208, 2, p. 309-314 6 p.

  Research output: Contribution to journal › Article › peer-review
  31 Citations (Scopus)

• Inhibition of the kinase WNK1/HSN2 ameliorates neuropathic pain by restoring GABA inhibition

  Kahle, K. T., Schmouth, J-F., Lavastre, V., Latremoliere, A., Zhang, J., Andrews, N., Omura, T., Laganière, J., Rochefort, D., Hince, P., Castonguay, G., Gaudet, R., Mapplebeck, J. C. S., Sotocinal, S. G., Duan, J., Ward, C., Khanna, A. R., Mogil, J. S., Dion, P. A., Woolf, C. J. & 2 others, Inquimbert, P. & Rouleau, G. A., 29 Mar 2016, In: Science Signaling. 9, 421, 9 p., ra32.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Phosphorylation
  • Neuralgia
  • gamma-Aminobutyric Acid
  • Neurons
  • Phosphotransferases
  29 Citations (Scopus)

  162 Downloads (Pure)

• Inhibition of the protective effect of cyclophosphamide by pre-treatment with buthionine sulfoximine

  Carmichael, J., Friedman, N., Tochner, Z., Adams, D. J., Roland Wolf, C., Mitchell, J. B. & Russo, A., 1 Jul 1986, In: International Journal of Radiation Oncology, Biology, Physics. 12, 7 PART 1, p. 1191-1193 3 p.

  Research output: Contribution to journal › Article › peer-review

  • buthionine
  • Buthionine Sulfoximine
  • pretreatment
  • Cyclophosphamide
  • bone marrow
  15 Citations (Scopus)

• Inhibition of tissue angiotensin converting enzyme activity prevents malignant hypertension in TGR(mREN2)27

  Montgomery, H. E., Kiernan, L. A., Whitworth, C. E., Fleming, S., Unger, T., Gohlke, P., Mullins, J. J. & McEwan, J. R., 1998, In: Journal of Hypertension. 16, 5, p. 635-43 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Malignant Hypertension
  • Peptidyl-Dipeptidase A
  • Blood Pressure
  • Angiotensin-Converting Enzyme Inhibitors
  • Heterozygote
  47 Citations (Scopus)

• Inhibition of trypanothione reductase and glutathione reductase by ferrocenic 4-aminoquinoline ureas

  Blackie, M. A. L., Saravanamuthu, A., Fairlamb, A. H. & Chibale, K., 2008, In: ARKIVOC. 2008, vi, p. 52-60 9 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Inhibition of USP10 induces degradation of oncogenic FLT3

  Weisberg, E. L., Schauer, N. J., Yang, J., Lamberto, I., Doherty, L., Bhatt, S., Nonami, A., Meng, C., Letai, A., Wright, R., Tiv, H., Gokhale, P. C., Ritorto, M. S., De Cesare, V., Trost, M., Christodoulou, A., Christie, A., Weinstock, D. M., Adamia, S., Stone, R. & 8 others, Chauhan, D., Anderson, K. C., Seo, H-S., Dhe-Paganon, S., Sattler, M., Gray, N. S., Griffin, J. D. & Buhrlage, S. J., 2 Oct 2017, In: Nature Chemical Biology. 13, p. 1207-1215 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Acute Myeloid Leukemia
  • Phosphotransferases
  • Deubiquitinating Enzymes
  • Proteasome Endopeptidase Complex
  • Ubiquitin
  46 Citations (Scopus)

• Inhibition of Y1 receptor signaling improves islet transplant outcome

  Loh, K., Shi, Y. C., Walters, S., Bensellam, M., Lee, K., Dezaki, K., Nakata, M., Ip, C. K., Chan, J. Y., Gurzov, E. N., Thomas, H. E., Waibel, M., Cantley, J., Kay, T. W., Yada, T., Laybutt, D. R., Grey, S. T. & Herzog, H., 1 Dec 2017, In: Nature Communications. 8, 1, 12 p., 490.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Transplants
  • insulin
  • Islets of Langerhans Transplantation
  • Medical problems
  • Insulin
  9 Citations (Scopus)

  13 Downloads (Pure)

• Inhibitor‐2 functions like a chaperone to fold three expressed isoforms of mammalian protein phosphatase‐1 into a conformation with the specificity and regulatory properties of the native enzyme

  Alessi, D. R., Street, A. J., Cohen, P. & Cohen, P. T. W., May 1993, In: European Journal of Biochemistry. 213, 3, p. 1055-1066 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Conformations
  • Catalytic Domain
  • Protein Isoforms
  • Muscle
  • Enzymes
  166 Citations (Scopus)

• Inhibitors against Fungal Cell Wall Remodeling Enzymes

  Delso, I., Valero-Gonzalez, J., Gomollón-Bel, F., Castro-López, J., Fang, W., Navratilova, I., van Aalten, D. M. F., Tejero, T., Merino, P. & Hurtado-Guerrero, R., 22 Jan 2018, In: ChemMedChem. 13, 2, p. 128-132 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Glucans
  • Cell Wall
  • Cells
  • X ray crystallography
  • Lead compounds
  3 Citations (Scopus)

  194 Downloads (Pure)

• Inhibitors incorporating zinc-binding groups target the GlcNAc-PI de-N-acetylase in Trypanosoma brucei, the causative agent of African sleeping sickness

  Abdelwahab, N. Z., Crossman, A. T., Sullivan, L., Ferguson, M. A. J. & Urbaniak, M. D., Mar 2012, In: Chemical Biology & Drug Design. 79, 3, p. 270-278 9 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• Inhibitors of dihydrofolate reductase in leishmania and trypanosomes

  Gilbert, I. H., 18 Jul 2002, In: Biochimica et Biophysica Acta. Molecular Basis of Disease. 1587, 2-3, p. 249-257 9 p.

  Research output: Contribution to journal › Article › peer-review
  92 Citations (Scopus)

• Inhibitors of human histone deacetylase with potent activity against the African trypanosome Trypanosoma brucei

  Kelly, J. M., Taylor, M. C., Horn, D., Loza, E., Kalvinsh, I. & Bjorkling, F., 1 Mar 2012, In: Bioorganic & Medicinal Chemistry Letters. 22, 5, p. 1886-1890 5 p.

  Research output: Contribution to journal › Article › peer-review
  18 Citations (Scopus)

• Inhibitors of receptor tyrosine kinases do not suppress progesterone-induced [Ca2+]i signalling in human spermatozoa

  Kirkman-Brown, J. C., Lefièvre, L., Bray, C., Stewart, P. M., Barratt, C. L. R. & Publicover, S. J., 1 Apr 2002, In: Molecular Human Reproduction. 8, 4, p. 326-332 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Receptor Protein-Tyrosine Kinases
  • Spermatozoa
  • Progesterone
  • Genistein
  • Acrosome Reaction
  22 Citations (Scopus)

• Inhibitors of the kinase IspE: structure-activity relationships and co-crystal structure analysis

  Hirsch, A. K. H., Alphey, M. S., Lauw, S., Seet, M., Barandun, L., Eisenreich, W., Rohdich, F., Hunter, W. N., Bacher, A. & Diederich, F., 2008, In: Organic and Biomolecular Chemistry. 6, 15, p. 2719-2730 12 p.

  Research output: Contribution to journal › Article › peer-review
  30 Citations (Scopus)

  20 Downloads (Pure)

• Inhibitors of trypanothione reductase as potential antitrypanosomal drugs

  Chan, C., Yin, H., Garforth, J., McKie, J. H., Jaouhari, R. A., Douglas, K. T., Fairlamb, A. H. & Croft, S. L., 1 Jan 1995, In: Biochemical Society Transactions. 23, 4, p. 511S-511S 1 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Inhibitors of tubulin assembly identified through screening a compound library

  Morgan, R. E., Ahn, S., Nzimiro, S., Fotie, J., Phelps, M. A., Cotrill, J., Yakovich, A. J., Sackett, D. L., Dalton, J. T. & Werbovetz, K. A., Dec 2008, In: Chemical Biology & Drug Design. 72, 6, p. 513-524 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Tubulin Modulators
  • Tubulin
  • Screening
  • Libraries
  • Inhibitory Concentration 50
  12 Citations (Scopus)

• Inhibitory effects of the gastrin receptor antagonist CR2093 on basal, gastrin-stimulated and growth factor-stimulated growth of the rat pancreatic cell line AR42J

  Watson, S. A., Clifford, T. L. & Steele, R. J. C., 1994, In: Anti-Cancer Drugs. 5, 5, p. 591-597 7 p.

  Research output: Contribution to journal › Article › peer-review

  • CR 2093
  • gastrin 17
  • Cholecystokinin B Receptor
  • Gastrins
  • Epidermal Growth Factor
  6 Citations (Scopus)

• Inhibitory effects of urine on the polymerase chain reaction for cytomegalovirus DNA

  Khan, G., Kangro, H. O., Coates, P. J. & Heath, R. B., 1991, In: Journal of Clinical Pathology. 44, 5, p. 360-365 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Cytomegalovirus
  • Urine
  • Polymerase Chain Reaction
  • DNA
  • Urea
  177 Citations (Scopus)

• Inhomogeneous bimolecular recombination in partially crystallised tri-methylphenyl diamine glasses

  Goldie, D. M., 1 Jan 2013, In: Thin Solid Films. 527, p. 377-382 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Diamines
  • diamines
  • Glass
  • Photocurrents
  • glass
  1 Citation (Scopus)

• In-hospital prevention of cardiac arrest

  Smith, B. H., 2005, In: Journal of the Royal Naval Medical Service. 91, 1, p. 43-4 2 p.

  Research output: Contribution to journal › Article › peer-review

• Inhumanity's law: Crimes against humanity RtoP and South Sudan

  Waldorf, L., Jan 2016, In: International Politics. 53, 1, p. 49-66 18 p.

  Research output: Contribution to journal › Article › peer-review

  • South Sudan
  • Crimes against humanity
  • crime
  • responsibility
  • international politics
  1 Citation (Scopus)

• Initial arch wires for tooth alignment during orthodontic treatment with fixed appliances

  Jian, F., Lai, W., Furness, S., McIntyre, G. T., Millett, D. T., Hickman, J. & Wan, Y., 2013, In: Cochrane Database of Systematic Reviews. 2013, 4, CD007859.

  Research output: Contribution to journal › Article › peer-review

  • Fixed Orthodontic Appliances
  • Orthodontics
  • Tooth
  • Orthodontic Brackets
  • Root Resorption
  24 Citations (Scopus)

• Initial cardiovascular treatment patterns during the first 90 days following an incident cardiovascular event

  Ma, T-T., Wong, I. C. K., Whittlesea, C., Mackenzie, I. S., Man, K. K. C., Lau, W., Brauer, R. & Wei, L., 9 Jul 2020, (E-pub ahead of print) In: British Journal of Clinical Pharmacology. 87, 3, p. 1043-1055 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Polypharmacy
  • Cardiovascular Agents
  • Coronary Disease
  • Smoking
  • Stroke
  9 Downloads (Pure)

• Initial characterization of a rat model of diabetic nephropathy

  Nobrega, M. A., Fleming, S., Roman, R. J., Shiozawa, M., Schlick, N., Lazar, J. & Jacob, H. J., 2004, In: Diabetes. 53, 3, p. 735-42 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Diabetic Nephropathies
  • Kidney
  • Focal Segmental Glomerulosclerosis
  • Genetic Background
  • Basement Membrane
  63 Citations (Scopus)

• Initial characterization of fast laser scanning optical CT apparatus for 3-D dosimetry

  Krstajić, N. & Doran, S., 2009, In: Journal of Physics: Conference Series. 164, 1, p. 1-5 5 p., 012022.

  Research output: Contribution to journal › Article › peer-review

  • dosimeters
  • tomography
  • scanning
  • charge coupled devices
  • characterization
  2 Citations (Scopus)

• Initial experience of 3 Tesla versus conventional field strength magnetic resonance imaging of small functioning pituitary tumours

  Stobo, D. B., Lindsay, R. S., Connell, J. M., Dunn, L. & Forbes, K. P., Nov 2011, In: Clinical Endocrinology. 75, 5, p. 673-677 5 p.

  Research output: Contribution to journal › Article › peer-review
  25 Citations (Scopus)

• Initial impacts of global risk mitigation measures taken during the combatting of the COVID-19 pandemic

  Bruinen de Bruin, Y., Lequarre, A-S., McCourt, J., Clevestig, P., Pigazzani, F., Zare Jeddi, M., Colosio, C. & Goulart, M., Aug 2020, In: Anatomical Science International. 128, p. 1-8 8 p., 104773.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Coronavirus
  • Pandemics
  • Disease Outbreaks
  • SARS Virus
  • Emergency Responders
  71 Citations (Scopus)

  110 Downloads (Pure)

• Initial management of infertility: An audit of pre-referral investigations and exploration of couples' views at the interface of primary and secondary care

  Morrison, C., Bhattacharya, S., Hamilton, M., Templeton, A. & Smith, B., 29 Mar 2007, In: Human Fertility. 10, 1, p. 25-31 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Secondary Care
  • Infertility
  • Primary Health Care
  • Referral and Consultation
  • Semen Analysis
  13 Citations (Scopus)

• Initiating 'The Methodology of Jacques Rancière': How Does it All Start?

  Mercieca, D. P., Jul 2012, In: Studies in Philosophy and Education. 31, 4, p. 407-417 11 p.

  Research output: Contribution to journal › Article › peer-review

  • emancipation
  • Emancipation
  • Methodology
  • methodology
  • teacher
  5 Citations (Scopus)

• Initiation and evolution of debonding phenomena in layered structures

  Funari, M. F. & Lonetti, P., Dec 2017, In: Theoretical and Applied Fracture Mechanics. 92, p. 133-145 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Debonding
  • Coalescence
  • Multilayers
  • Moving Mesh
  • formulations
  27 Citations (Scopus)

• Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs

  Blow, J. J. & Laskey, R. A., 21 Nov 1986, In: Cell. 47, 4, p. 577-587 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Eggs
  • Cell Extracts
  • Xenopus
  • DNA Replication
  • DNA
  436 Citations (Scopus)

• Initiation of insulin adjustment for carbohydrate at onset of diabetes in children using a home‐based education programme with a bolus calculator

  Thom, H., Greene, S., Alexander, V., Ramsay, V., Bluff, S., Mackenzie, L., Sturrock, C. & Conway, N. T., 2016, In: Practical Diabetes. 33, 1, p. 19-22a 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Carbohydrates
  • Insulin
  • Education
  • Blood Glucose
  • Child

• Initiation of neuronal differentiation requires PI3-kinase/TOR signalling in the vertebrate neural tube

  Fishwick, K. J., Li, R. A., Halley, P., Deng, P. & Storey, K. G., 15 Feb 2010, In: Developmental Biology. 338, 2, p. 215-225 11 p.

  Research output: Contribution to journal › Article › peer-review
  48 Citations (Scopus)

• Injuries in Quidditch: a Descriptive Epidemiological Study

  Pennington, R., Cooper, A., Edmond, E., Faulkner, A., Reidy, M. J. & Davies, P. S. E., Oct 2017, In: International Journal of Sports Physical Therapy. 12, 5, p. 833-839 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Epidemiologic Studies
  • Sports
  • Wounds and Injuries
  • Athletes
  • Safety

• Inke Näthke: The ABCs of APC

  Sedwick, C. & Nathke, I., 2010, In: Journal of Cell Biology. 189, 5, p. 774-775 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  117 Downloads (Pure)

• In Memoriam: Lynn R Fraser

  Aitken, R. J. & Barratt, C. L. R., 24 May 2020, In: Andrology. 8, 3, p. 532-534 3 p.

  Research output: Contribution to journal › Article

• In memoriam Memoria

  Willson, P. R., 1993, In: Gender and History. 5, 3, p. 416-420 5 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• In memory: Nikolay Kirov Nikolov

  Petrov, M. & Reynolds, S., 3 Dec 2014, In: Journal of Physics: Conference Series. 558, 1, 1 p., 011003.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  99 Downloads (Pure)

• Inn1 and Cyk3 regulate chitin synthase during cytokinesis in budding yeasts

  Devrekanli, A., Foltman, M., Roncero, C., Sanchez-Diaz, A. & Labib, K., 15 Nov 2012, In: Journal of Cell Science. 125, 22, p. 5453-5466 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Chitin Synthase
  • C2 Domains
  • Saccharomycetales
  • Cytokinesis
  • Catalytic Domain
  27 Citations (Scopus)

• Inn1 couples contraction of the actomyosin ring to membrane ingression during cytokinesis in budding yeast

  Sanchez-Diaz, A., Marchesi, V., Murray, S., Jones, R., Pereira, G., Edmondson, R., Allen, T. & Labib, K., Apr 2008, In: Nature Cell Biology. 10, 4, p. 395-406 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Actomyosin
  • Saccharomycetales
  • Cytokinesis
  • C2 Domains
  • Membranes
  59 Citations (Scopus)

• Innate activation of human primary epithelial cells broadens the host response to Mycobacterium tuberculosis in the airways

  Reuschl, A-K., Edwards, M. R., Parker, R., Connell, D. W., Hoang, L., Halliday, A., Jarvis, H., Siddiqui, N., Wright, C., Bremang, S., Newton, S. M., Beverley, P., Shattock, R. J., Kon, O. M. & Lalvani, A., 1 Sep 2017, In: PLoS Pathogens. 13, 9, p. 1-26 26 p., e1006577.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Mycobacterium tuberculosis
  • Tuberculosis
  • Epithelial Cells
  • Alveolar Macrophages
  • Infection
  24 Citations (Scopus)

  73 Downloads (Pure)

• Innate DNA sensing moves to the nucleus

  Unterholzner, L. & Bowie, A. G., 19 May 2011, In: Cell Host & Microbe. 9, 5, p. 351-353 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Human Herpesvirus 8
  • Inflammasomes
  • Viral DNA
  • DNA
  • Cytosol
  20 Citations (Scopus)