Find Research outputs

Search results

• Article

  Hypokalemic and ECG sequelae of combined beta-agonist/diuretic therapy: protection by conventional doses of spironolactone but not triamterene

  Lipworth, B. J., McDevitt, D. G. & Struthers, A. D., 1990, In: Chest. 98, 4, p. 811-815 5 p.

  Research output: Contribution to journal › Article › peer-review
  14 Citations (Scopus)

• Hypo-METRICS: Hypoglycaemia - MEasurement, ThResholds and ImpaCtS - A multi-country clinical study to define the optimal threshold and duration of sensor-detected hypoglycaemia that impact the experience of hypoglycaemia, quality of life and health economic outcomes: the study protocol

  Divilly, P., Zaremba, N., Mahmoudi, Z., Søholm, U., Pollard, D. J., Broadley, M., Abbink, E. J., de Galan, B., Pedersen-Bjergaard, U., Renard, E., Evans, M., Speight, J., Brennan, A., McCrimmon, R. J., Müllenborn, M., Heller, S., Seibold, A., Mader, J. K., Amiel, S. A., Pouwer, F., & 2 othersChoudhary, P. & Hypo-RESOLVE Consortium, Sep 2022, In: Diabetic Medicine. 39, 9, 11 p., e14892.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  40 Downloads (Pure)

• Hypomorphic mutation of PDK1 suppresses tumorigenesis in PTEN(+/-) mice

  Bayascas, J. R., Leslie, N., Parsons, R., Fleming, S. & Alessi, D., Oct 2005, In: Current Biology. 15, 20, p. 1839-1846 8 p.

  Research output: Contribution to journal › Article › peer-review
  130 Citations (Scopus)

• Hypomorphic promoter mutation in PIGM causes inherited glycosylphosphatidylinositol deficiency

  Almeida, A. M., Murakami, Y., Layton, D. M., Hillmen, P., Sellick, G. S., Maeda, Y., Richards, S., Patterson, S., Kotsianidis, I., Mollica, L., Crawford, D. H., Baker, A., Ferguson, M., Roberts, I., Houlston, R., Kinoshita, T. & Karadimitris, A., Jul 2006, In: Nature Medicine. 12, 7, p. 846-851 6 p.

  Research output: Contribution to journal › Article › peer-review
  183 Citations (Scopus)

• Hypophosphorylation of Mdm2 augments p53 stability

  Blattner, C., Hay, T., Meek, D. W. & Lane, D. P., Sep 2002, In: Molecular and Cellular Biology. 22, 17, p. 6170-6182 13 p.

  Research output: Contribution to journal › Article › peer-review
  125 Citations (Scopus)

• Hypophysitis induced by immune checkpoint inhibitors in a Scottish melanoma population: Immune checkpoint inhibitor toxicity

  Wei, K. Z., Baxter, M. & Casasola, R., 18 Apr 2019, In: Melanoma Management. 6, 1, 12 p., MMT13.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  106 Downloads (Pure)

• Hyporesponsiveness to alpha-adrenoceptor agonists in cirrhotic patients is not evident when human hepatic and mesenteric arteries are studied in vitro

  Hadoke, P. W. F., Dillon, J. F., Walker, S. W., Williams, B. C., John, T. G. & Hayes, P. C., Apr 1996, In: British Journal of Pharmacology. 117, S1, p. 111p-111p 1 p.

  Research output: Contribution to journal › Article › peer-review

• Hypothalamic AMP-activated protein kinase activation with AICAR amplifies counterregulatory responses to hypoglycemia in a rodent model of type 1 diabetes

  Fan, X., Ding, Y., Brown, S., Zhou, L., Shaw, M., Vella, M. C., Cheng, H., Mcnay, E. C., Sherwin, R. S. & McCrimmon, R., 2009, In: American Journal of Physiology - Regulatory, Integrative and Comparative Physiology (AJP - Regulatory, Integrative and Comparative Physiology) . 296, 6, p. R1702-R1708 7 p.

  Research output: Contribution to journal › Article › peer-review
  37 Citations (Scopus)

• Hypothalamic ATP-sensitive K + channels play a key role in sensing hypoglycemia and triggering counterregulatory epinephrine and glucagon responses

  Evans, M. L., McCrimmon, R. J., Flanagan, D. E., Keshavarz, T., Fan, X., McNay, E. C., Jacob, R. J. & Sherwin, R. S., Oct 2004, In: Diabetes. 53, 10, p. 2542-2551 10 p.

  Research output: Contribution to journal › Article › peer-review
  133 Citations (Scopus)

• Hypothalamic Fkbp51 is induced by fasting, and elevated hypothalamic expression promotes obese phenotypes

  Yang, L., Isoda, F., Yen, K., Kleopoulos, S. P., Janssen, W., Fan, X., Mastaitis, J., Dunn-Meynell, A., Levin, B., McCrimmon, R., Sherwin, R., Musatov, S. & Mobbs, C. V., 2012, In: AJP - Endocrinology and Metabolism (Endocrinology and Metabolism. 302, 8, p. E987-E991 5 p.

  Research output: Contribution to journal › Article › peer-review
  21 Citations (Scopus)

• Hypothesis: persistent expression of fetal phenotypic characteristics by fibroblasts is associated with an increased susceptibility to neoplastic disease

  Schor, S. L., Schor, A. M., Howell, A. & Crowther, D., 1987, In: Experimental cell biology. 55, 1, p. 11-7 7 p.

  Research output: Contribution to journal › Article › peer-review
  36 Citations (Scopus)

• Hypothesis and preliminary data to suggest carbon monoxide as the mediator of the hyperdynamic circulation of cirrhosis?

  Dillon, J. F., Selby, C., Hadoke, P. W. F., Therapondos, G., Mohaddin, S., Walker, S. W. & Hayes, P. C., Dec 1998, In: Medical Biochemistry. 1, 1, p. 93-96 4 p.

  Research output: Contribution to journal › Article › peer-review

  1 Citation (Scopus)

• Hypothetical economic analysis of screening for left ventricular hypertrophy in high-risk normotensive populations

  Witham, M. D., Davies, J. I., Dawson, A., Davey, P. G. & Struthers, A. D., 2004, In: QJM : an International Journal of Medicine. 97, 2, p. 87-93 7 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• 'Hypothetical facts' and the balance of probabilities

  Symon, A., 1 Jan 2007, In: British Journal of Midwifery. 15, 3, p. 171-172 2 p.

  Research output: Contribution to journal › Article › peer-review

• Hypoxemia during diagnostic laparoscopy: A prospective study

  Haydon, G. H., Dillon, J., Simpson, K. J., Thomas, H. & Hayes, P. C., 1 Jan 1996, In: Gastrointestinal Endoscopy. 44, 2, p. 124-128 5 p.

  Research output: Contribution to journal › Article › peer-review
  15 Citations (Scopus)

• Hypoxia activates IKK-NF-κB and the immune response in Drosophila melanogaster

  Bandarra, D., Biddlestone, J., Mudie, S., Muller, H. A. & Rocha, S., 2014, In: Bioscience Reports. 34, 4, p. 429-440 12 p., e00127.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  25 Citations (Scopus)

  181 Downloads (Pure)

• Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism

  Watts, E. R., Howden, A. J. M., Morrison, T., Sadiku, P., Hukelmann, J. L., von Kriegsheim, A., Ghesquière, B., Murphy, F., Mirchandani, A. S., Humphries, D. C., Grecian, R., Ryan, E. M., Coelho, P., Rodriguez-Blanco, G., Plant, T. M., Dickinson, R. S., Finch, A. J., Vermaelen, W., Cantrell, D. A., Whyte, M. K. B., & 1 othersWalmsley, S. R., 17 May 2021, In: Journal of Clinical Investigation. 131, 10, 17 p., e134073.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  7 Citations (Scopus)

  38 Downloads (Pure)

• Hypoxia Induced NF-κB

  D'Ignazio, L. & Rocha, S., 8 Mar 2016, In: Cells. 5, 1, 8 p., 10.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  83 Citations (Scopus)

  141 Downloads (Pure)

• Hypoxia induces rapid changes to histone methylation and reprograms chromatin

  Batie, M., Frost, J., Frost, M., Wilson, J. W., Schofield, P. & Rocha, S., 15 Mar 2019, In: Science. 363, 6432, p. 1222-1226 5 p.

  Research output: Contribution to journal › Article › peer-review
  154 Citations (Scopus)

• Hypoxia-inducible factor 1α is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif

  Land, S. C. & Tee, A. R., Jul 2007, In: Journal of Biological Chemistry. 282, 28, p. 20534-20543 10 p.

  Research output: Contribution to journal › Article › peer-review
  398 Citations (Scopus)

• Hypoxia inhibits human recombinant large conductance, Ca²⁺-activated K⁺ (maxi-K) channels by a mechanism which is membrane delimited and Ca²⁺ sensitive

  Lewis, A., Peers, C., Ashford, M. L. J. & Kemp, P. J., 1 May 2002, In: Journal of Physiology. 540, 3, p. 771-780 10 p.

  Research output: Contribution to journal › Article › peer-review
  69 Citations (Scopus)

• Hypoxia is not the primary mechanism contributing to exercise-induced proteinuria

  Joyce, K. E., Delamere, J., Bradwell, S., Myers, S. D., Ashdown, K., Rue, C., Lucas, S. J. E., Thomas, O. D., Fountain, A., Edsell, M., Myers, F., Malein, W., Imray, C., Clarke, A., Lewis, C. T., Newman, C., Johnson, B., Cadigan, P., Wright, A. & Bradwell, A., 26 Mar 2020, In: BMJ Open Sport and Exercise Medicine. 6, 1, p. 1-10 10 p., e000662.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  2 Citations (Scopus)

  37 Downloads (Pure)

• Hypoxia-mediated control of HIF/ARNT machinery in epidermal keratinocytes

  Weir, L., Robertson, D., Leigh, I. M., Vass, J. K. & Panteleyev, A. A., Jan 2011, In: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1813, 1, p. 60-72 13 p.

  Research output: Contribution to journal › Article › peer-review
  28 Citations (Scopus)

• Hypoxic activation of an amiloride-sensitive cation conductance in alveolar epithelial cells

  Jovanovic, S., Land, S. C., Olver, R. E. & Wilson, S. M., 2001, In: Biochemical and Biophysical Research Communications. 286, 3, p. 622-7 6 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Hypoxic pulmonary vasoconstriction: mechanisms of oxygen-sensing

  Evans, A. M., Hardie, D. G., Peers, C. & Mahmoud, A., Feb 2011, In: Current Opinion in Anaesthesiology. 24, 1, p. 13-20 8 p.

  Research output: Contribution to journal › Article › peer-review
  50 Citations (Scopus)

• Hysteresis and non-uniqueness in the speed of the onset of instability in curtain coating

  Marston, J. O., Decent, S. P. & Simmons, M. J. H., Dec 2006, In: Journal of Fluid Mechanics. 569, p. 349-363 15 p.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• Hysteretic Implications for Graded Bed Load Transport in Symmetrical Hydrograph Flows

  Wang, L., Wang, D., Cuthbertson, A., Zhong, D. & Pender, G., 24 Dec 2021, In: Frontiers in Environmental Science. 9, 14 p., 800832.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  16 Downloads (Pure)

• Hysteroscopic and laparoscopic management of caesarean scar (niche) defects in symptomatic patients

  Brown, K. & Tkacz, Z., Jul 2018, In: Journal of Obstetrics & Gynaecology. 38, 5, p. 730 1 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• I. Luxembourg, Brussels and now the Hague: Congestion in the promotion of free movement in parental responsibility matters

  McEleavy, P., 2010, In: International and Comparative Law Quarterly. 59, 2, p. 505-519 15 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Ian Kennedy Artist Interview

  Vaughan, P., Apr 2013, In: Studies in Comics. 4, 1, p. 15-33 19 p.

  Research output: Contribution to journal › Article › peer-review

• Ian Paisley's facing into a possible by-election ... he can be heartened by his likely re-election

  Muinzer, T., 14 Sep 2018, thejournal.ie.

  Research output: Contribution to specialist publication › Article

• Iatrogenic profound hypoalphalipoproteinemia: an unrecognized cause of very-low hdl cholesterol

  Murphy, M. J., Duncan, A., Vallance, B. D., Packard, C. J. & O'Reilly, D. S. J., 1 Aug 1995, In: Postgraduate Medical Journal. 71, 838, p. 498-500 3 p.

  Research output: Contribution to journal › Article › peer-review
  3 Citations (Scopus)

• Iatrogenic sexual dysfunction and the protective withholding of information: in whose best interest?

  Barker, P., Begley, C. M. & Higgins, A., Aug 2006, In: Journal of Psychiatric and Mental Health Nursing. 13, 4, p. 437-446 10 p.

  Research output: Contribution to journal › Article › peer-review
  24 Citations (Scopus)

• IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes

  Momozawa, Y., Dmitrieva, J., Théâtre, E., Deffontaine, V., Rahmouni, S., Charloteaux, B., Crins, F., Docampo, E., Elansary, M., Gori, A. S., Lecut, C., Mariman, R., Mni, M., Oury, C., Altukhov, I., Alexeev, D., Aulchenko, Y., Amininejad, L., Bouma, G., Hoentjen, F., & 15 othersLöwenberg, M., Oldenburg, B., Pierik, M. J., Vander Meulen-De Jong, A. E., Van Der Woude, C. J., Visschedijk, M. C., Lathrop, M., Hugot, J. P., Weersma, R. K., De Vos, M., Franchimont, D., Vermeire, S., Kubo, M., Louis, E. & Georges, M., 21 Jun 2018, In: Nature Communications. 9, 1, p. 1-18 18 p., 2427.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  98 Citations (Scopus)

  82 Downloads (Pure)

• IBMPFD disease-causing mutant VCP/p97 proteins are targets of autophagic-lysosomal degradation

  Bayraktar, O., Oral, O., Kocaturk, N. M., Akkoc, Y., Eberhart, K., Kosar, A. & Gozuacik, D., 21 Oct 2016, In: PLoS ONE. 11, 10, 19 p., e0164864.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  24 Citations (Scopus)

  32 Downloads (Pure)

• IC261, a specific inhibitor of the protein kinases casein kinase 1-delta and -epsilon, triggers the mitotic checkpoint and induces p53-dependent postmitotic effects

  Behrend, L., Milne, D. M., Stöter, M., Deppert, W., Campbell, L. E., Meek, D. W. & Knippschild, U., 2000, In: Oncogene. 19, 47, p. 5303-5313 11 p.

  Research output: Contribution to journal › Article › peer-review
  104 Citations (Scopus)

• ICBS & ECBS Chemical Biology Meeting 2015 - Let them come to Berlin!

  Komatsu, T. & Virdee, S., 20 May 2016, In: ACS Chemical Biology. 11, 5, p. 1159-1166 8 p.

  Research output: Contribution to journal › Article

  Open Access

  File
  3 Citations (Scopus)

  133 Downloads (Pure)

• "ICDAS"--an international system for caries detection and assessment being developed to facilitate caries epidemiology, research and appropriate clinical management

  Pitts, N., 2004, In: Community Dental Health. 21, 3, p. 193-8 6 p.

  Research output: Contribution to journal › Article › peer-review
  313 Citations (Scopus)

• Ice-collapse induced waves and graded gravel ridges on a Lake Beach

  Duck, R. W. & McManus, J., 1981, In: Earth Surface Processes and Landforms. 6, 2, p. 203-206

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Ice-cored moraine degradation mapped and quantified using an unmanned aerial vehicle: A case study from a polythermal glacier in Svalbard

  Tonkin, T. N., Midgley, N. G., Cook, S. J. & Graham, D. J., 1 Apr 2016, In: Geomorphology. 258, p. 1-10 10 p.

  Research output: Contribution to journal › Article › peer-review
  59 Citations (Scopus)

• Icelandic climate and glacier fluctuations through the termination of the "little ice age"

  Kirkbride, M. P., 2002, In: Polar Geography. 26, 2, p. 116-133 18 p.

  Research output: Contribution to journal › Article › peer-review
  14 Citations (Scopus)

• Ichthyosis vulgaris: novel FLG mutations in the German population and high presence of CD1a+ cells in the epidermis of the atopic subgroup

  Oji, V., Seller, N., Sandilands, A., Gruber, R., Gerss, J., Hüffmeier, U., Hamm, H., Emmert, S., Aufenvenne, K., Metze, D., Luger, T., Loser, K., Hausser, I., Traupe, H. & McLean, W. H. I., 2009, In: British Journal of Dermatology. 160, 4, p. 771-781 11 p.

  Research output: Contribution to journal › Article › peer-review
  29 Citations (Scopus)

• I-COPTIC: Implementation of community pharmacy-based testing for hepatitis C: Delphi consensus protocol

  23 Aug 2022, (E-pub ahead of print) In: International Journal of Pharmacy Practice. 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  18 Downloads (Pure)

• ICOS coreceptor signaling inactivates the transcription factor FOXO1 to promote Tfh cell differentiation

  Stone, E. L., Pepper, M., Katayama, C. D., Kerdiles, Y. M., Lai, C-Y., Emslie, E., Lin, Y. C., Yang, E., Goldrath, A. W., Li, M. O., Cantrell, D. A. & Hedrick, S. M., 17 Feb 2015, In: Immunity. 42, 2, p. 239-251 13 p.

  Research output: Contribution to journal › Article › peer-review
  154 Citations (Scopus)

• ICT in science education: A quasi-experimental study of achievement, attitudes toward science, and career aspirations of Korean middle school students

  Park, H. R., Khan, S. & Petrina, S., May 2009, In: International Journal of Science Education. 31, 8, p. 993-1012 20 p.

  Research output: Contribution to journal › Article › peer-review
  28 Citations (Scopus)

• ICU-talk: the development of a computerised communication aid for patients in ICU

  Etchels, M. C., MacAulay, F., Judson, A., Ashraf, S., Ricketts, I. W., Waller, A., Alm, N., Warden, A., Gordon, B., Brodie, J. & Shearer, A. J., 2003, In: Care of the Critically Ill. 19, 1, p. 4-9 6 p.

  Research output: Contribution to journal › Article › peer-review

  10 Citations (Scopus)

• Idealism Without Idealism: badiou's materialist renaissance

  Ruda, F., 13 Jun 2014, In: Angelaki. 19, 1, p. 83-98 16 p.

  Research output: Contribution to journal › Article › peer-review
  7 Citations (Scopus)

• Ideal manipulation angle and instrument length in hand-assisted laparoscopic surgery

  Manasnayakorn, S., Cuschieri, A. & Hanna, G. B., Apr 2008, In: Surgical Endoscopy. 22, 4, p. 924-929 6 p.

  Research output: Contribution to journal › Article › peer-review
  23 Citations (Scopus)

• Ideal relaxation of the Hopf fibration

  Smiet, C. B., Candelaresi, S. & Bouwmeester, D., Jul 2017, In: Physics of Plasmas. 24, 7, p. 1-11 11 p., 072110.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  3 Citations (Scopus)

  204 Downloads (Pure)

• Identification, diagnosis and treatment of heart failure: could we do better?

  Struthers, A. D., 1996, In: Cardiology. 87 , Suppl 1, p. 29-32 4 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)