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Inhibition of protein kinase CK2 by condensed polyphenolic derivatives. An in vitro and in vivo study
Meggio, F., Pagano, M. A., Moro, S., Zagotto, G., Ruzzene, M., Sarno, S., Cozza, G., Bain, J., Elliott, M., Deana, A. D., Brunati, A. M. & Pinna, L. A., 1 Oct 2004, In: Biochemistry. 43, 40, p. 12931-12936 6 p.Research output: Contribution to journal › Article › peer-review
86 Citations (Scopus) -
Inhibition of Protein Kinase CK2 Closes the CFTR Cl- Channel, but has no Effect on the Cystic Fibrosis Mutant Delta F508-CFTR
Treharne, K. J., Xu, Z., Chen, J-H., Best, O. G., Cassidy, D. M., Gruenert, D. C., Hegyi, P., Gray, M. A., Sheppard, D. N., Kunzelmann, K. & Mehta, A., 2009, In: Cellular Physiology and Biochemistry. 24, 5-6, p. 347-360 14 p.Research output: Contribution to journal › Article › peer-review
28 Citations (Scopus) -
Inhibition of proton-translocating transhydrogenase from photosynthetic bacteria by N,N′-dicyclohexylcarbodiimide
Palmer, T., Williams, R., Cotton, N. P. J., Thomas, C. M. & Jackson, J. B., 1 Feb 1993, In: European Journal of Biochemistry. 211, 3, p. 663-669 7 p.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus) -
Inhibition of Rho at different stages of thymocyte development gives different perspectives on Rho function
Cleverley, S., Henning, S. & Cantrell, D., 17 Jun 1999, In: Current Biology. 9, 12, p. 657-660 4 p.Research output: Contribution to journal › Article › peer-review
Open Access33 Citations (Scopus) -
Inhibition of SAPK2a/p38 prevents hnRNP A0 phosphorylation by MAPKAP-K2 and its interaction with cytokine mRNAs
Rousseau, S., Morrice, N., Peggie, M., Campbell, D. G., Gaestel, M. & Cohen, P., Dec 2002, In: The EMBO Journal. 21, 23, p. 6505-6514 10 p.Research output: Contribution to journal › Article › peer-review
183 Citations (Scopus) -
Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages
Darling, N. J., Toth, R., Arthur, J. S. C. & Clark, K., 3 Feb 2017, In: Biochemical Journal. 474, 4, p. 521-537 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile35 Citations (Scopus)215 Downloads (Pure) -
Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity
Liu, J., Albers, M. W., Wandless, T. J., Luan, S., Alberg, D. G., Belshaw, P. J., Cohen, P. ., MacKintosh, C., Klee, C. B. & Schreiber, S. L., 1992, In: Biochemistry. 31, 16, p. 3896-3901 6 p.Research output: Contribution to journal › Article › peer-review
499 Citations (Scopus) -
Inhibition of thalamic excitability by 4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine-3-ol: a selective role for delta-GABA(A) receptors
Herd, M. B., Foister, N., Chandra, D., Peden, D. R., Homanics, G. E., Brown, V. J., Balfour, D. J. K., Lambert, J. J. & Belelli, D., Mar 2009, In: European Journal of Neuroscience. 29, 6, p. 1177-1187 11 p.Research output: Contribution to journal › Article › peer-review
59 Citations (Scopus) -
Inhibition of the ERCC1-XPF structure-specific endonuclease to overcome cancer chemoresistance
McNeil, E. M., Astell, K. R., Ritchie, A. M., Shave, S., Houston, D. R., Bakrania, P., Jones, H. M., Khurana, P., Wallace, C., Chapman, T., Wear, M. A., Walkinshaw, M. D., Saxty, B. & Melton, D. W., 1 Jul 2015, In: DNA Repair. 31, p. 19-28 10 p.Research output: Contribution to journal › Article › peer-review
52 Citations (Scopus) -
Inhibition of the G2 DNA Damage Checkpoint and of Protein Kinases Chk1 and Chk2 by the Marine Sponge Alkaloid Debromohymenialdisine
Curman, D., Cinel, B., Williams, D. E., Rundle, N., Block, W. D., Goodarzi, A. A., Hutchins, J. R., Clarke, P. R., Zhou, B. B., Lees-Miller, S. P., Andersen, R. J. & Roberge, M., 25 Jan 2001, In: Journal of Biological Chemistry. 276, 21, p. 17914-17919 6 p.Research output: Contribution to journal › Article › peer-review
119 Citations (Scopus) -
Inhibition of the GlcNAc transferase of the glycosylphosphatidylinositol anchor biosynthesis in African trypanosomes
Milne, K. G., Ferguson, M. & Masterson, W. J., Sep 1992, In: European Journal of Biochemistry. 208, 2, p. 309-314 6 p.Research output: Contribution to journal › Article › peer-review
31 Citations (Scopus) -
Inhibition of the kinase WNK1/HSN2 ameliorates neuropathic pain by restoring GABA inhibition
Kahle, K. T., Schmouth, J-F., Lavastre, V., Latremoliere, A., Zhang, J., Andrews, N., Omura, T., Laganière, J., Rochefort, D., Hince, P., Castonguay, G., Gaudet, R., Mapplebeck, J. C. S., Sotocinal, S. G., Duan, J., Ward, C., Khanna, A. R., Mogil, J. S., Dion, P. A., Woolf, C. J., & 2 others , 29 Mar 2016, In: Science Signaling. 9, 421, 9 p., ra32.Research output: Contribution to journal › Article › peer-review
Open AccessFile35 Citations (Scopus)208 Downloads (Pure) -
Inhibition of the protective effect of cyclophosphamide by pre-treatment with buthionine sulfoximine
Carmichael, J., Friedman, N., Tochner, Z., Adams, D. J., Roland Wolf, C., Mitchell, J. B. & Russo, A., 1 Jul 1986, In: International Journal of Radiation Oncology - Biology - Physics (IJROBP). 12, 7 PART 1, p. 1191-1193 3 p.Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus) -
Inhibition of tissue angiotensin converting enzyme activity prevents malignant hypertension in TGR(mREN2)27
Montgomery, H. E., Kiernan, L. A., Whitworth, C. E., Fleming, S., Unger, T., Gohlke, P., Mullins, J. J. & McEwan, J. R., 1998, In: Journal of Hypertension. 16, 5, p. 635-43 9 p.Research output: Contribution to journal › Article › peer-review
48 Citations (Scopus) -
Inhibition of trypanothione reductase and glutathione reductase by ferrocenic 4-aminoquinoline ureas
Blackie, M. A. L., Saravanamuthu, A., Fairlamb, A. H. & Chibale, K., 2008, In: ARKIVOC. 2008, vi, p. 52-60 9 p.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
Inhibition of USP10 induces degradation of oncogenic FLT3
Weisberg, E. L., Schauer, N. J., Yang, J., Lamberto, I., Doherty, L., Bhatt, S., Nonami, A., Meng, C., Letai, A., Wright, R., Tiv, H., Gokhale, P. C., Ritorto, M. S., De Cesare, V., Trost, M., Christodoulou, A., Christie, A., Weinstock, D. M., Adamia, S., Stone, R., & 8 others , 2 Oct 2017, In: Nature Chemical Biology. 13, p. 1207-1215 9 p.Research output: Contribution to journal › Article › peer-review
74 Citations (Scopus) -
Inhibition of Y1 receptor signaling improves islet transplant outcome
Loh, K., Shi, Y. C., Walters, S., Bensellam, M., Lee, K., Dezaki, K., Nakata, M., Ip, C. K., Chan, J. Y., Gurzov, E. N., Thomas, H. E., Waibel, M., Cantley, J., Kay, T. W., Yada, T., Laybutt, D. R., Grey, S. T. & Herzog, H., 1 Dec 2017, In: Nature Communications. 8, 1, 12 p., 490.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)41 Downloads (Pure) -
Inhibitor‐2 functions like a chaperone to fold three expressed isoforms of mammalian protein phosphatase‐1 into a conformation with the specificity and regulatory properties of the native enzyme
Alessi, D. R., Street, A. J., Cohen, P. & Cohen, P. T. W., May 1993, In: European Journal of Biochemistry. 213, 3, p. 1055-1066 12 p.Research output: Contribution to journal › Article › peer-review
Open Access167 Citations (Scopus) -
Inhibitors against Fungal Cell Wall Remodeling Enzymes
Delso, I., Valero-Gonzalez, J., Gomollón-Bel, F., Castro-López, J., Fang, W., Navratilova, I., van Aalten, D. M. F., Tejero, T., Merino, P. & Hurtado-Guerrero, R., 22 Jan 2018, In: ChemMedChem. 13, 2, p. 128-132 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)329 Downloads (Pure) -
Inhibitors incorporating zinc-binding groups target the GlcNAc-PI de-N-acetylase in Trypanosoma brucei, the causative agent of African sleeping sickness
Abdelwahab, N. Z., Crossman, A. T., Sullivan, L., Ferguson, M. A. J. & Urbaniak, M. D., Mar 2012, In: Chemical Biology & Drug Design. 79, 3, p. 270-278 9 p.Research output: Contribution to journal › Article › peer-review
7 Citations (Scopus) -
Inhibitors of dihydrofolate reductase in leishmania and trypanosomes
Gilbert, I. H., 18 Jul 2002, In: BBA - Molecular Basis of Disease. 1587, 2-3, p. 249-257 9 p.Research output: Contribution to journal › Article › peer-review
100 Citations (Scopus) -
Inhibitors of human histone deacetylase with potent activity against the African trypanosome Trypanosoma brucei
Kelly, J. M., Taylor, M. C., Horn, D., Loza, E., Kalvinsh, I. & Bjorkling, F., 1 Mar 2012, In: Bioorganic & Medicinal Chemistry Letters. 22, 5, p. 1886-1890 5 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
Inhibitors of receptor tyrosine kinases do not suppress progesterone-induced [Ca2+]i signalling in human spermatozoa
Kirkman-Brown, J. C., Lefièvre, L., Bray, C., Stewart, P. M., Barratt, C. L. R. & Publicover, S. J., 1 Apr 2002, In: Molecular Human Reproduction. 8, 4, p. 326-332 7 p.Research output: Contribution to journal › Article › peer-review
23 Citations (Scopus) -
Inhibitors of the kinase IspE: structure-activity relationships and co-crystal structure analysis
Hirsch, A. K. H., Alphey, M. S., Lauw, S., Seet, M., Barandun, L., Eisenreich, W., Rohdich, F., Hunter, W. N., Bacher, A. & Diederich, F., 2008, In: Organic and Biomolecular Chemistry. 6, 15, p. 2719-2730 12 p.Research output: Contribution to journal › Article › peer-review
31 Citations (Scopus)20 Downloads (Pure) -
Inhibitors of trypanothione reductase as potential antitrypanosomal drugs
Chan, C., Yin, H., Garforth, J., McKie, J. H., Jaouhari, R. A., Douglas, K. T., Fairlamb, A. H. & Croft, S. L., 1 Jan 1995, In: Biochemical Society Transactions. 23, 4, p. 511S-511S 1 p.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus) -
Inhibitors of tubulin assembly identified through screening a compound library
Morgan, R. E., Ahn, S., Nzimiro, S., Fotie, J., Phelps, M. A., Cotrill, J., Yakovich, A. J., Sackett, D. L., Dalton, J. T. & Werbovetz, K. A., Dec 2008, In: Chemical Biology & Drug Design. 72, 6, p. 513-524 12 p.Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus) -
Inhibitory effects of the gastrin receptor antagonist CR2093 on basal, gastrin-stimulated and growth factor-stimulated growth of the rat pancreatic cell line AR42J
Watson, S. A., Clifford, T. L. & Steele, R. J. C., 1994, In: Anti-Cancer Drugs. 5, 5, p. 591-597 7 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
Inhibitory effects of urine on the polymerase chain reaction for cytomegalovirus DNA
Khan, G., Kangro, H. O., Coates, P. J. & Heath, R. B., 1991, In: Journal of Clinical Pathology. 44, 5, p. 360-365 6 p.Research output: Contribution to journal › Article › peer-review
188 Citations (Scopus) -
Inhomogeneous bimolecular recombination in partially crystallised tri-methylphenyl diamine glasses
Goldie, D. M., 1 Jan 2013, In: Thin Solid Films. 527, p. 377-382 6 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
In-hospital prevention of cardiac arrest
Smith, B. H., 2005, In: Journal of the Royal Naval Medical Service. 91, 1, p. 43-4 2 p.Research output: Contribution to journal › Article › peer-review
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Inhumanity's law: Crimes against humanity RtoP and South Sudan
Waldorf, L., Jan 2016, In: International Politics. 53, 1, p. 49-66 18 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Initial 50 consecutive full-robotic pancreatoduodenectomies without conversion by a single surgeon: a learning curve analysis from a tertiary referral high-volume center
Morelli, L., Furbetta, N., Palmeri, M., Guadagni, S., Di Franco, G., Gianardi, D., Cervelli, R., Lorenzoni, V., Comandatore, A., Carpenito, C., Di Candio, G. & Cuschieri, A., 3 Jan 2023, (E-pub ahead of print) In: Surgical Endoscopy. p. 1-9 9 p.Research output: Contribution to journal › Article › peer-review
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Initial arch wires for tooth alignment during orthodontic treatment with fixed appliances
Jian, F., Lai, W., Furness, S., McIntyre, G. T., Millett, D. T., Hickman, J. & Wan, Y., 2013, In: Cochrane Database of Systematic Reviews. 2013, 4, CD007859.Research output: Contribution to journal › Article › peer-review
32 Citations (Scopus) -
Initial cardiovascular treatment patterns during the first 90 days following an incident cardiovascular event
Ma, T-T., Wong, I. C. K., Whittlesea, C., Mackenzie, I. S., Man, K. K. C., Lau, W., Brauer, R. & Wei, L., 2 Mar 2021, In: British Journal of Clinical Pharmacology. 87, 3, p. 1043-1055 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)32 Downloads (Pure) -
Initial characterization of a rat model of diabetic nephropathy
Nobrega, M. A., Fleming, S., Roman, R. J., Shiozawa, M., Schlick, N., Lazar, J. & Jacob, H. J., 2004, In: Diabetes. 53, 3, p. 735-42 8 p.Research output: Contribution to journal › Article › peer-review
70 Citations (Scopus) -
Initial characterization of fast laser scanning optical CT apparatus for 3-D dosimetry
Krstajić, N. & Doran, S., 2009, In: Journal of Physics: Conference Series. 164, 1, p. 1-5 5 p., 012022.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Initial experience of 3 Tesla versus conventional field strength magnetic resonance imaging of small functioning pituitary tumours
Stobo, D. B., Lindsay, R. S., Connell, J. M., Dunn, L. & Forbes, K. P., Nov 2011, In: Clinical Endocrinology. 75, 5, p. 673-677 5 p.Research output: Contribution to journal › Article › peer-review
30 Citations (Scopus) -
Initial Experience Using the Gore Embolic Filter in Carotid Interventions
Hornung, M., Franke, J., Bertog, S. C., Gafoor, S., Grunwald, I. & Sievert, H., Aug 2016, In: Journal of Invasive Cardiology. 28, 8, p. 334-9 6 p.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
Initial impacts of global risk mitigation measures taken during the combatting of the COVID-19 pandemic
Bruinen de Bruin, Y., Lequarre, A-S., McCourt, J., Clevestig, P., Pigazzani, F., Zare Jeddi, M., Colosio, C. & Goulart, M., Aug 2020, In: Safety Science. 128, p. 1-8 8 p., 104773.Research output: Contribution to journal › Article › peer-review
Open AccessFile186 Citations (Scopus)165 Downloads (Pure) -
Initial management of infertility: An audit of pre-referral investigations and exploration of couples' views at the interface of primary and secondary care
Morrison, C., Bhattacharya, S., Hamilton, M., Templeton, A. & Smith, B., 29 Mar 2007, In: Human Fertility. 10, 1, p. 25-31 7 p.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus) -
Initiating a crystallographic study of trypanothione reductase
Hunter, W. N., Smith, K., Derewenda, Z., Harrop, S. J., Habash, J., Islam, M. S., Helliwell, J. R. & Fairlamb, A. H., 20 Nov 1990, In: Journal of Molecular Biology. 216, 2, p. 235-237 3 p.Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus) -
Initiating 'The Methodology of Jacques Rancière': How Does it All Start?
Mercieca, D. P., Jul 2012, In: Studies in Philosophy and Education. 31, 4, p. 407-417 11 p.Research output: Contribution to journal › Article › peer-review
7 Citations (Scopus) -
Initiation and evolution of debonding phenomena in layered structures
Funari, M. F. & Lonetti, P., Dec 2017, In: Theoretical and Applied Fracture Mechanics. 92, p. 133-145 13 p.Research output: Contribution to journal › Article › peer-review
32 Citations (Scopus) -
Initiation of DNA replication in nuclei and purified DNA by a cell-free extract of Xenopus eggs
Blow, J. J. & Laskey, R. A., 21 Nov 1986, In: Cell. 47, 4, p. 577-587 11 p.Research output: Contribution to journal › Article › peer-review
449 Citations (Scopus) -
Initiation of insulin adjustment for carbohydrate at onset of diabetes in children using a home‐based education programme with a bolus calculator
Thom, H., Greene, S., Alexander, V., Ramsay, V., Bluff, S., Mackenzie, L., Sturrock, C. & Conway, N. T., 2016, In: Practical Diabetes. 33, 1, p. 19-22a 5 p.Research output: Contribution to journal › Article › peer-review
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Initiation of neuronal differentiation requires PI3-kinase/TOR signalling in the vertebrate neural tube
Fishwick, K. J., Li, R. A., Halley, P., Deng, P. & Storey, K. G., 15 Feb 2010, In: Developmental Biology. 338, 2, p. 215-225 11 p.Research output: Contribution to journal › Article › peer-review
51 Citations (Scopus) -
Injuries in Quidditch: A Prospective Study from a Complete UK Season
Pennington, R., Cooper, A., Faulkner, A. C., MacInnes, A., Greensmith, T. S. W., Mayne, A. I. W. & Davies, P. S. E., 1 Oct 2021, In: International Journal of Sports Physical Therapy. 16, 5, p. 1338-1344 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile40 Downloads (Pure) -
Injuries in Quidditch: a Descriptive Epidemiological Study
Pennington, R., Cooper, A., Edmond, E., Faulkner, A., Reidy, M. J. & Davies, P. S. E., Oct 2017, In: International Journal of Sports Physical Therapy. 12, 5, p. 833-839 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Inke Näthke: The ABCs of APC
Sedwick, C. & Nathke, I., 2010, In: Journal of Cell Biology. 189, 5, p. 774-775 2 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile143 Downloads (Pure) -
Ink formulation and printing of electrolyte for a doped ceria solid oxide fuel cell
Ahmed, M., Jones, T. D. A. & Abdolvand, A., 15 Nov 2022, In: Materials Letters. 327, p. 1-4 4 p., 132999.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Downloads (Pure)