Find Research Outputs

Search results

• Article

  Pharmacists Attitudes and Role in Diabetes Management in Kuwait

  Al-Haqan, A. A., Al-Taweel, D., Awad, A. & Wake, D., May 2017, In: Medical Principles and Practice: International Journal of the Kuwait University Health Science Centre. 26, 3, p. 273-279 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Kuwait
  • Pharmacists
  • Pharmaceutical Services
  • Disease Management
  • Hypoglycemia
  8 Citations (Scopus)

  228 Downloads (Pure)

• Pharmacists' experiences and perceptions about simulation use for learning and development of clinical skills in Kuwait

  Katoue, M. G. & Ker, J., Dec 2019, In: International Journal of Clinical Pharmacy. 41, 6, p. 1451-1461 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Kuwait
  • Clinical Competence
  • Pharmacists
  • Education
  • Learning
  1 Citation (Scopus)

• Pharmacoepidemiological research at the Medicines Monitoring Unit, Scotland: Data protection and confidentiality

  Evans, J. M. M., McNaughton, D., Donnan, P. T. & MacDonald, T. M., 1 Jan 2001, In: Pharmacoepidemiology and Drug Safety. 10, 7, p. 669-673 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Computer Security
  • Confidentiality
  • Scotland
  • Data Anonymization
  • Privacy
  16 Citations (Scopus)

• Pharmacogenetic analysis of GLCCI1 in three north European pediatric asthma populations with a reported use of inhaled corticosteroids

  Vijverberg, S. J. H., Tavendale, R., Leusink, M., Koenderman, L., Raaijmakers, J. A. M., Postma, D. S., Koppelman, G. H., Turner, S. W., Mukhopadhyay, S., Palmer, C. N. A. & Maitland-Van Der Zee, A. H., Apr 2014, In: Pharmacogenomics. 15, 6, p. 799-806 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Pharmacogenomic Testing
  • Adrenal Cortex Hormones
  • Asthma
  • Pediatrics
  • Population
  20 Citations (Scopus)

• Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins

  Postmus, I., Trompet, S., Deshmukh, H. A., Barnes, M. R., Li, X., Warren, H. R., Chasman, D. I., Zhou, K., Arsenault, B. J., Donnelly, L. A., Wiggins, K. L., Avery, C. L., Griffin, P., Feng, Q., Taylor, K. D., Li, G., Evans, D. S., Smith, A. V., de Keyser, C. E., Johnson, A. D. & 32 others, de Craen, A. J. M., Stott, D. J., Buckley, B. M., Ford, I., Westendorp, R. G. J., Eline Slagboom, P., Sattar, N., Munroe, P. B., Sever, P., Poulter, N., Stanton, A., Shields, D. C., O'Brien, E., Shaw-Hawkins, S., Ida Chen, Y-D., Nickerson, D. A., Smith, J. D., Pierre Dubé, M., Matthijs Boekholdt, S., Kees Hovingh, G., Kastelein, J. J. P., McKeigue, P. M., Betteridge, J., Neil, A., Durrington, P. N., Doney, A., Carr, F., Morris, A., Palmer, C. N. A., Colhoun, H. M., Jukema, J. W. & Caulfield, M. J., 28 Oct 2014, In: Nature Communications. 5, p. 1-10 10 p., 5068.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pharmacogenetics
  • Pharmacogenomic Testing
  • genome
  • cholesterol
  • Genome-Wide Association Study
  138 Citations (Scopus)

  254 Downloads (Pure)

• Pharmacogenetics

  Wolf, C. R., Smith, G. & Smith, R. L., 2000, In: British Medical Journal. 320, 7240, p. 987-90 4 p.

  Research output: Contribution to journal › Article › peer-review
  214 Citations (Scopus)

• Pharmacogenetics

  Wolf, C. R. & Smith, G., 1999, In: British Medical Bulletin. 55, 2, p. 366-86 21 p.

  Research output: Contribution to journal › Article › peer-review

  • Pharmacogenetics
  • Cytochrome P-450 CYP2D6
  • Drug-Related Side Effects and Adverse Reactions
  • Pharmaceutical Preparations
  • Drug Prescriptions
  94 Citations (Scopus)

• Pharmacogenetics in diabetes

  Pearson, E. R., Apr 2009, In: Current Diabetes Reports. 9, 2, p. 172-181 10 p.

  Research output: Contribution to journal › Article › peer-review
  34 Citations (Scopus)

• Pharmacogenetics in type 2 diabetes: Influence on response to oral hypoglycemic agents

  Dawed, A. Y., Zhou, K. & Pearson, E. R., 6 Apr 2016, In: Pharmacogenomics and Personalized Medicine. 9, p. 17-29 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pharmacogenetics
  • Hypoglycemic Agents
  • Type 2 Diabetes Mellitus
  • Genetic Markers
  • Treatment Failure
  15 Citations (Scopus)

  200 Downloads (Pure)

• Pharmacogenetics of inhaled long-acting beta2-agonists in asthma: a systematic review

  Slob, E. M. A., Vijverberg, S. J. H., Palmer, C. N. A., Zazuli, Z., Farzan, N., Oliveri, N. M. B., Pijnenburg, M. W., Koppelman, G. H. & Maitland van der Zee, A. H., Nov 2018, In: Pediatric Allergy and Immunology. 29, 7, p. 705-714 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pharmacogenetics
  • Asthma
  • Systematic Reviews
  • Pharmacogenomic Testing
  • Child
  9 Citations (Scopus)

  231 Downloads (Pure)

• Pharmacogenomics of statin-related myopathy: Meta-analysis of rare variants from whole-exome sequencing

  PREDICTION-ADR Consortium, EUDRAGENE, Floyd, J. S., Bloch, K. M., Brody, J. A., Maroteau, C., Siddiqui, M. K., Gregory, R., Carr, D. F., Molokhia, M., Liu, X., Bis, J. C., Ahmed, A., Liu, X., Hallberg, P., Yue, Q., Magnusson, P. K. E., Brisson, D., Wiggins, K. L., Morrison, A. C. & 23 others, Khoury, E., McKeigue, P., Stricker, B. H., Lapeyre-Mestre, M., Heckbert, S. R., Gallagher, A. M., Chinoy, H., Gibbs, R. A., Bondon-Guitton, E., Tracy, R., Boerwinkle, E., Gaudet, D., Conforti, A., Van Staa, T., Sitlani, C. M., Rice, K. M., Maitland-van der Zee, A., Wadelius, M., Morris, A. P., Pirmohamed, M., Palmer, C. N. A., Psaty, B. M. & Alfirevic, A., 26 Jun 2019, In: PLoS ONE. 14, 6, p. 1-13 13 p., e0218115.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pharmacogenetics
  • drug toxicity
  • muscular diseases
  • Whole Exome Sequencing
  • meta-analysis
  7 Citations (Scopus)

  108 Downloads (Pure)

• Pharmacokinetic and pharmacodynamic comparison of hydrofluoroalkane and chlorofluorocarbon formulations of budesonide

  Clearie, K. L., Williamson, P. A., Meldrum, K., Gillen, M., Carlsson, L-G., Carlholm, M., Ekelund, J. & Lipworth, B. J., Apr 2011, In: British Journal of Clinical Pharmacology. 71, 4, p. 504-513 10 p.

  Research output: Contribution to journal › Article › peer-review
  24 Citations (Scopus)

• Pharmacokinetic interaction of the antiparasitic agents ivermectin and spinosad in dogs

  Dunn, S. T., Hedges, L., Sampson, K. E., Lai, Y., Mahabir, S., Balogh, L. & Locuson, C. W., 1 May 2011, In: Drug Metabolism and Disposition. 39, 5, p. 789-795 7 p.

  Research output: Contribution to journal › Article › peer-review

  • spinosad
  • Antiparasitic Agents
  • Ivermectin
  • Pharmacokinetics
  • Dogs
  30 Citations (Scopus)

• Pharmacokinetics, efficacy and adverse effects of sublingual salbutamol in patients with asthma

  Lipworth, B. J., Clark, R. A., Dhillon, D. P., Moreland, T. A., Struthers, A. D., Clark, G. A. & McDevitt, D. G., 1989, In: European Journal of Clinical Pharmacology. 37, 6, p. 567-571 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Albuterol
  • Metered Dose Inhalers
  • Tablets
  • Asthma
  • Pharmacokinetics
  35 Citations (Scopus)

• Pharmacokinetics, Metabolism, Biodistribution, Radiation Dosimetry, and Toxicology of F-18-Fluoroacetate (F-18-FACE) in Non-human Primates

  Nishii, R., Tong, W., Wendt, R., Soghomonyan, S., Mukhopadhyay, U., Balatoni, J., Mawlawi, O., Bidaut, L., Tinkey, P., Borne, A., Alauddin, M., Gonzalez-Lepera, C., Yang, B. & Gelovani, J. G., Apr 2012, In: Molecular Imaging and Biology. 14, 2, p. 213-224 12 p.

  Research output: Contribution to journal › Article › peer-review
  17 Citations (Scopus)

• Pharmacokinetics and pharmacodynamics of orally administered acetylenic tricyclic bis(cyanoenone), a highly potent Nrf2 activator with a reversible covalent mode of action

  Kostov, R. V., Knatko, E. V., McLaughlin, L. A., Henderson, C. J., Zheng, S., Huang, J. T. J., Honda, T. & Dinkova-Kostova, A. T., 25 Sep 2015, In: Biochemical and Biophysical Research Communications. 465, 3, p. 402-407 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • TBE 31
  • Pharmacodynamics
  • Pharmacokinetics
  • Kelch-Like ECH-Associated Protein 1
  • Cysteine
  11 Citations (Scopus)

  162 Downloads (Pure)

• Pharmacokinetics of metformin in patients with gastrointestinal intolerance

  McCreight, L., Stage, T. B., Connelly, P., Lonergan, M., Nielsen, F., Prehn, C., Adamski, J., Brosen, K. & Pearson, E. R., 1 Jul 2018, In: Diabetes, Obesity & Metabolism. 20, 7, p. 1593-1601 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Metformin
  • Pharmacokinetics
  • Bile Acids and Salts
  • Lactic Acid
  • Serotonin
  12 Citations (Scopus)

  205 Downloads (Pure)

• Pharmacokinetics of β-Lactam Antibiotics: Clues from the Past to Help Discover Long-Acting Oral Drugs in the Future

  Smith, P. W., Zuccotto, F., Bates, R. H., Martinez-Martinez, M. S., Read, K. D., Peet, C. & Epemolu, O., 12 Oct 2018, In: ACS Infectious Diseases. 4, 10, p. 1439-1447 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Lactams
  • Pharmacokinetics
  • Anti-Bacterial Agents
  • Pharmaceutical Preparations
  • Drug Discovery
  9 Citations (Scopus)

  168 Downloads (Pure)

• Pharmacological characterization of a rat 5-hydroxytryptamine type₃ receptor subunit (r5-HT(3A(b)) expressed in Xenopus laevis oocytes

  Mair, I. D., Lambert, J. J., Yang, J., Dempster, J. & Peters, J. A., Aug 1998, In: British Journal of Pharmacology. 124, 8, p. 1667-1674 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Serotonin Receptors
  • Xenopus laevis
  • Oocytes
  • Serotonin
  • Pharmacology
  28 Citations (Scopus)

• Pharmacological characterization of the apparent splice variants of the murine 5-HT₃ R-A subunit expressed in Xenopus laevis oocytes

  Downie, D. L., Hope, A. G., Lambert, J. J., Peters, J. A., Blackburn, T. P. & Jones, B. J., Mar 1994, In: Neuropharmacology. 33, 3-4, p. 473-482 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Xenopus laevis
  • Oocytes
  • Serotonin
  • Pharmacology
  • BRL 46470
  45 Citations (Scopus)

• Pharmacological disruption of the MID1/α4 interaction reduces mutant Huntingtin levels in primary neuronal cultures

  Monteiro, O., Chen, C., Bingham, R., Argyrou, A., Buxton, R., Jönsson, C. P., Jones, E., Bridges, A., Gatfield, K., Krauß, S., Lambert, J., Langston, R., Schweiger, S. & Uings, I., 23 Apr 2018, In: Neuroscience Letters. 673, p. 44-50 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Huntington Disease
  • Pharmacology
  • Peptides
  • Huntingtin Protein
  • Human Immunodeficiency Virus Proteins
  2 Citations (Scopus)

  294 Downloads (Pure)

• Pharmacological inhibition of ATM by KU55933 stimulates ATM transcription

  Khalil, H. S., Tummala, H., Hupp, T. R. & Zhelev, N., 1 Jun 2012, In: Experimental Biology and Medicine. 237, 6, p. 622-634 13 p.

  Research output: Contribution to journal › Article › peer-review

  • 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one
  • Ataxia Telangiectasia
  • Transcription
  • Pharmacology
  • DNA
  11 Citations (Scopus)

• Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy

  Petherick, K. J., Conway, O. J. L., Mpamhanga, C., Osborne, S. A., Kamal, A., Saxty, B. & Ganley, I. G., 1 May 2015, In: Journal of Biological Chemistry. 290, 18, p. 11376-11383 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • MRT67307
  • TOR Serine-Threonine Kinases
  • Protein-Serine-Threonine Kinases
  • Autophagy
  • Cells
  118 Citations (Scopus)

• Pharmacological management of neuropathic pain in non-specialist settings: summary of NICE guidance

  Tan, T., Barry, P., Reken, S., Baker, M. & Smith, B., 2010, In: British Medical Journal. 340, p. c1079

  Research output: Contribution to journal › Article › peer-review
  84 Citations (Scopus)

• Pharmacological profiling of the Dictyostelium adenylate cyclases ACA, ACB and ACG

  Alvarez-Curto, E., Weening, K. E. & Schaap, P., 1 Jan 2007, In: Biochemical Journal. 401, 1, p. 309-16 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Dictyostelium
  • cinnamonitrile
  • 2',3'-isopropylideneadenosine
  • Adenylyl Cyclases
  • Genes
  23 Citations (Scopus)

• Pharmacological properties of the enhanced-affinity glucocorticoid fluticasone furoate in vitro and in an in vivo model of respiratory inflammatory disease

  Salter, M., Biggadike, K., Matthews, J. L., West, M. R., Haase, M. V., Farrow, S. N., Uings, I. J. & Gray, D. W., 2007, In: American Journal of Physiology: Lung Cellular and Molecular Physiology. 293, 3, p. L660-7 8 p.

  Research output: Contribution to journal › Article › peer-review

  • fluticasone furoate
  • Glucocorticoids
  • Pharmacology
  • In Vitro Techniques
  • Glucocorticoid Receptors
  130 Citations (Scopus)

• Pharmacological treatment and perceived health status during 1-year follow up in patients diagnosed with coronary artery disease, but ineligible for revascularization: results from the Euro Heart Survey on Coronary Revascularization

  Lenzen, M., Scholte op Reimer, W., Norekval, T. M., De Geest, S., Fridlund, B., Heikkila, J., Jaarsma, T., Martensson, J., Moons, P., Smith, K., Stewart, S., Stromberg, A., Thompson, D. R. & Wijns, W., Jun 2006, In: European Journal of Cardiovascular Nursing. 5, 2, p. 115-121 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Health Status
  • Coronary Artery Disease
  • Pharmacology
  • Heart
  • Therapeutics
  27 Citations (Scopus)

• Pharmacological treatment of attention-deficit/hyperactivity disorder: assessing outcomes

  Adamo, N., Seth, S. & Coghill, D., Jul 2015, In: Expert Review of Clinical Pharmacology. 8, 4, p. 383-397 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Attention Deficit Disorder with Hyperactivity
  • Pharmacology
  • Safety
  • Consensus
  • Cognition
  12 Citations (Scopus)

• Pharmacological validation of N-myristoyltransferase as a drug target in Leishmania donovani

  Corpas Lopez, V., Moniz, S., Thomas, M., Wall, R., Torrie, L., Zander-Dinse, D., Tinti, M., Brand, S., Stojanovski, L., Manthri, S., Hallyburton, I., Zuccotto, F., Wyatt, P., De Rycker, M., Horn, D., Ferguson, M., Clos, J., Read, K., Fairlamb, A., Gilbert, I. & 1 others, Wyllie, S., 11 Jan 2019, In: ACS Infectious Diseases. 5, 1, p. 111-122 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • glycylpeptide N-tetradecanoyltransferase
  • Leishmania donovani
  • 2,6-dichloro-N-(difluoromethyl)-4-(3-(1-methylpiperidin-4-yl)propyl)-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)benzenesulfonamide
  • Pharmacology
  • Parasites
  12 Citations (Scopus)

  195 Downloads (Pure)

• Pharmacologic or genetic manipulation of glutathione S-transferase P1-1 (GST ∏) influences cell proliferation pathways

  Ruscoe, J. E., Rosario, L. A., Wang, T., Gate, L., Arifoglu, P., Wolf, C. R., Henderson, C. J., Ronai, Z. & Tew, K. D., 1 Jul 2001, In: Journal of Pharmacology and Experimental Therapeutics. 298, 1, p. 339-345 7 p.

  Research output: Contribution to journal › Article › peer-review
  152 Citations (Scopus)

• Pharmacology, signaling and physiological relevance of the G protein-coupled receptor 55

  Balenga, N. A. B., Henstridge, C. M., Kargl, J. & Waldhoer, M., 2011, In: Current Vascular Pharmacology. 62, p. 251-277 27 p.

  Research output: Contribution to journal › Article › peer-review

  • Endocannabinoids
  • G-Protein-Coupled Receptors
  • Pharmacology
  • Cannabinoid Receptors
  • Dronabinol
  25 Citations (Scopus)

• Pharmacophore features distributions in different classes of compounds

  Zuccotto, F., Sep 2003, In: Journal of Chemical Information and Computer Sciences. 43, 5, p. 1542-1552 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Molecules
  • Hydrogen bonds
  • drug
  • Screening
  • Throughput
  20 Citations (Scopus)

• Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis

  Finnerup, N. B., Attal, N., Haroutounian, S., McNicol, E., Baron, R., Dworkin, R. H., Gilron, I., Haanpää, M., Hansson, P., Jensen, T. S., Kamerman, P. R., Lund, K., Moore, A., Raja, S. N., Rice, A. S. C., Rowbotham, M., Sena, E., Siddall, P., Smith, B. H. & Wallace, M., Feb 2015, In: Lancet Neurology. 14, 2, p. 162-173 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Neuralgia
  • Meta-Analysis
  • Systematic Reviews
  • Drug Therapy
  • Tramadol
  1372 Citations (Scopus)

• Pharmacotherapy of Raynaud’s phenomenon

  Belch, J. J. F. & Ho, M., Nov 1996, In: Drugs. 52, 5, p. 682-695 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Raynaud Disease
  • Drug Therapy
  • Calcium Channel Blockers
  • Pentoxifylline
  • Vasodilator Agents
  59 Citations (Scopus)

• Pharmacy support in developing prescribing skills

  McGuire, A., McEwan, T., Stafford, D. & Ker, J., Dec 2015, In: Clinical Teacher. 12, 6, p. 408-412 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Pharmacy
  • Pharmacists
  • Students
  • Learning
  • Education

• Phase 2 Trial of the DPP-1 Inhibitor Brensocatib in Bronchiectasis

  Chalmers, J. D., Haworth, C. S., Metersky, M. L., Loebinger, M. R., Blasi, F., Sibila, O., O'Donnell, A. E., Sullivan, E. J., Mange, K. C., Fernandez, C., Zou, J., Daley, C. L. & WILLOW Investigators, 7 Sep 2020, In: New England Journal of Medicine. 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Dipeptidyl-Peptidases and Tripeptidyl-Peptidases
  • Bronchiectasis
  • Protease Inhibitors
  • Placebos
  • Leukocyte Elastase

• Phase contrast imaging of breast tumours with synchrotron radiation

  Olivo, A., Rigon, L., Vinnicombe, S. J., Cheung, K. C., Ibison, M. & Speller, R. D., 2009, In: Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for use in Agriculture, Industry and Medicine. 67, 6, p. 1033-41 9 p.

  Research output: Contribution to journal › Article › peer-review

  • phase contrast
  • breast
  • tumors
  • synchrotron radiation
  • detectors
  31 Citations (Scopus)

• Phase dynamics of continuous topological upconversion in vortex beams

  Lopez-Mariscal, C., Burnham, D., Rudd, D., McGloin, D. & Gutierrez-Vega, J. C., 21 Jul 2008, In: Optics Express. 16, 15, p. 11411-11422 12 p.

  Research output: Contribution to journal › Article › peer-review
  18 Citations (Scopus)

• Phase equilibrium study in the CaO-K2O-B2O3-H2O system at 25°C

  Apagyi, Z. & Csetenyi, L. J., 1 Jul 2001, In: Cement and Concrete Research. 31, 7, p. 1087-1091 5 p.

  Research output: Contribution to journal › Article › peer-review

  • boron oxide
  • Phase equilibria
  • Potassium
  • Emission spectroscopy
  • Borates
  18 Citations (Scopus)

• Phase I/II trial of batimastat, a matrix metalloproteinase inhibitor, in patients with malignant ascites

  Parsons, S. L., Watson, S. A. & Steele, R. J. C., Dec 1997, In: European Journal of Surgical Oncology. 23, 6, p. 526-531 6 p.

  Research output: Contribution to journal › Article › peer-review

  • batimastat
  • Matrix Metalloproteinase Inhibitors
  • Ascites
  • Metalloproteases
  • Matrix Metalloproteinases
  74 Citations (Scopus)

• Phase Ib/II study of elisidepsin in metastatic or advanced gastroesophageal cancer (IMAGE trial)

  Petty, R., Anthoney, A., Metges, J-P., Alsina, M., Gonçalves, A., Brown, J. R., Montagut, C., Gunzer, K., Laus, G., Iglesias Dios, J. L., Miguel-Lillo, B., Bohan, P. & Salazar, R., Apr 2016, In: Cancer Chemotherapy and Pharmacology. 77, 4, p. 819-27 9 p.

  Research output: Contribution to journal › Article › peer-review

  • elisidepsin
  • Appointments and Schedules
  • Tumors
  • Neoplasms
  • Intravenous Infusions
  12 Citations (Scopus)

• Phase IIa randomized, placebo-controlled study of antimicrobial photodynamic therapy in bacterially colonized, chronic leg ulcers and diabetic foot ulcers: a new approach to antimicrobial therapy

  Morley, S., Griffiths, J., Philips, G., Moseley, H., O'Grady, C., Mellish, K., Lankester, C. L., Faris, B., Young, R. J., Brown, S. B. & Rhodes, L. E., 2013, In: British Journal of Dermatology. 168, 3, p. 617-624 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Leg Ulcer
  • Diabetic Foot
  • Photochemotherapy
  • Placebos
  • Bacterial Load
  75 Citations (Scopus)

• Phase II randomized preoperative window-of-opportunity study of the PI3K inhibitor pictilisib plus anastrozole compared with anastrozole alone in patients with estrogen receptor-positive breast cancer

  Schmid, P., Pinder, S. E., Wheatley, D., Macaskill, J., Zammit, C., Hu, J., Price, R., Bundred, N., Hadad, S., Shia, A., Sarker, S. J., Lim, L., Gazinska, P., Woodman, N., Korbie, D., Trau, M., Mainwaring, P., Gendreau, S., Lackner, M. R., Derynck, M. & 6 others, Wilson, T. R., Butler, H., Earl, G., Parker, P., Purushotham, A. & Thompson, A., 10 Jun 2016, In: Journal of Clinical Oncology. 34, 17, p. 1987-1994 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine
  • Anastrozole
  • Phosphatidylinositol 3-Kinases
  • Estrogen Receptors
  • Breast Neoplasms
  42 Citations (Scopus)

  203 Downloads (Pure)

• Phase-resolved X-ray spectroscopy of the millisecond pulsar SAX J1808.4-3658

  Gierliński, M., Done, C. & Barret, D., 21 Mar 2002, In: Monthly Notices of the Royal Astronomical Society. 331, 1, p. 141-153 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • X-ray spectroscopy
  • pulsars
  • neutron stars
  • accretion
  • spectroscopy
  75 Citations (Scopus)

• Phasertng: Directed acyclic graphs for crystallographic phasing

  McCoy, A. J., Stockwell, D. H., Sammito, M. D., Oeffner, R. D., Hatti, K. S., Croll, T. I. & Read, R. J., 1 Jan 2021, In: Acta Crystallographica Section D: Structural Biology. 77, Part 1, p. 1-10 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Software
  • Machine Learning
  • Triage
  • Computational Biology
  2 Downloads (Pure)

• Phasing the cholera toxin electron-diffraction data using the maximum entropy likelihood method with non-crystallographic symmetry imposed in the MICE computer program

  Nicholson, W. N. & Gilmore, C. J., 8 Aug 1996, In: Acta Crystallographica Section A: Foundations and Advances. 52, Suppl., p. C68 1 p.

  Research output: Contribution to journal › Article › peer-review

  • cholera
  • Electron diffraction
  • Entropy
  • Cholera Toxin
  • Diffraction

• PHD1 links cell-cycle progression to oxygen sensing through hydroxylation of the centrosomal protein Cep192

  Moser, S. C., Bensaddek, D., Ortmann, B., Maure, J-F., Mudie, S., Blow, J. J., Lamond, A. I., Swedlow, J. R. & Rocha, S., 26 Aug 2013, In: Developmental Cell. 26, 4, p. 381-392 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Hydroxylation
  • Prolyl Hydroxylases
  • Centrosome
  • Cells
  • Cell Cycle
  44 Citations (Scopus)

• Phe¹²⁰ contributes to the regiospecificity of cytochrome P450 2D6: Mutation leads to the formation of a novel dextromethorphan metabolite

  Flanagan, J. U., Maréchal, J. D., Ward, R., Kemp, C. A., McLaughlin, L. A., Sutcliffe, M. J., Roberts, G. C. K., Paine, M. J. I. & Wolf, C. R., 1 Jun 2004, In: Biochemical Journal. 380, 2, p. 353-360 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Dextromethorphan
  • Metabolites
  • Cytochrome P-450 CYP2D6
  • bufuralol
  • Mutation
  62 Citations (Scopus)

• PheGWAS: A new dimension to visualize GWAS across multiple phenotypes

  George, G., Gan, S., Huang, Y., Appleby, P., Nar, A. S., Venkatesan, R., Mohan, V., Palmer, C. N. A. & Doney, A. S. F., 15 Apr 2020, In: Bioinformatics. 36, 8, p. 2500-2505 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Lipids
  • Phenotype
  • Genome-Wide Association Study
  • Genetics
  • Genes
  76 Downloads (Pure)

• Phenformin, but not metformin, delays development of T-cell acute lymphoblastic leukemia/lymphoma via cell-autonomous AMPK activation

  Vara Ciruelos, D., Dandapani, M., Russell, F. M., Grzes, K., Atrih, A., Foretz, M., Viollet, B., Lamont, D. J., Cantrell, D. A. & Hardie, D. G., 16 Apr 2019, In: Cell Reports. 27, 3, p. 690-698.e4 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Phenformin
  • T-cells
  • Metformin
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma
  • Chemical activation
  15 Citations (Scopus)

  141 Downloads (Pure)