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A multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24.2, 17q23 and 19q13
Leslie, E. J., Carlson, J. C., Shaffer, J. R., Feingold, E., Wehby, G., Laurie, C. A., Jain, D., Laurie, C. C., Doheny, K. F., McHenry, T., Resick, J., Sanchez, C., Jacobs, J., Emanuele, B., Vieira, A. R., Neiswanger, K., Lidral, A. C., Valencia-Ramirez, L. C., Lopez-Palacio, A. M., Valencia, D. R. & 35 others, , 1 Jul 2016, In: Human Molecular Genetics. 25, 13, p. 2862-2872 11 p.Research output: Contribution to journal › Article › peer-review
86 Citations (Scopus) -
A multidisciplinary intervention to reduce antibiotic duration in lower respiratory tract infections
Murray, C., Shaw, A., Lloyd, M., Smith, R. P., Fardon, T. C., Schembri, S. & Chalmers, J. D., Feb 2014, In: Journal of Antimicrobial Chemotherapy. 69, 2, p. 515-518 4 p.Research output: Contribution to journal › Article › peer-review
29 Citations (Scopus) -
A multidisciplinary approach to vascular disease
Belch, J., 1993, In: Critical Ischaemia. 3, 3, p. 81-86 6 p.Research output: Contribution to journal › Comment/debate › peer-review
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A Multi-disciplinary Approach to the Archaeological Investigation of a Bedrock-Dominated Shallow-Marine Landscape: An example from the Bay of Firth, Orkney, UK
Bates, M. R., Nayling, N., Bates, R., Dawson, S., Huws, D. & Wickham-Jones, C., Mar 2013, In: International Journal of Nautical Archaeology. 42, 1, p. 24-43 20 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
A multidisciplinary approach to osteological research
Black, S. & Scheuer, L., 1995, In: Journal of Paleopathology. 7, 2, p. 78 1 p.Research output: Contribution to journal › Meeting abstract › peer-review
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A multidisciplinary approach to osteological research
Black, S. & Scheuer, L., 1996.Research output: Contribution to conference › Paper
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A multidimensional strategy to detect polypharmacological targets in the absence of structural and sequence homology
Durrant, J. D., Amaro, R. E., Xie, L., Urbaniak, M. D., Ferguson, M. A. J., Haapalainen, A., Chen, Z., Di Guilmi, A. M., Wunder, F., Bourne, P. E. & McCammon, J. A., Jan 2010, In: PLoS Computational Biology. 6, 1, p. - 8 p., e1000648.Research output: Contribution to journal › Article › peer-review
73 Citations (Scopus) -
A multidimensional approach to evaluating school-linked services: a school of social work and county public school partnership
Bronstein, L. R. & Kelly, T. B., 1998, In: Children and Schools. 20, 3, p. 152-64 12 p.Research output: Contribution to journal › Article › peer-review
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A multiclinic, placebo-controlled, double-blind study of prostaglandin E1 in Raynaud's syndrome
Mohrland, J. S., Porter, J. M., Smith, E. A., Belch, J. & Simms, M. H., 1985, In: Annals of the Rheumatic Diseases. 44, 11, p. 754-760 7 p.Research output: Contribution to journal › Article › peer-review
56 Citations (Scopus) -
A multicentre review of bakery and dental series allergens tested for cheilitis in the UK
Fatah, S., Horne, H. L., Wilkinson, S. M., Gawkrodger, D. J., English, J. S. C., Green, C. M., Ormerod, A. D., Chowdhury, M. M. U., Cooper, S. M., Stone, N. M., King, C. M. & Johnston, G. A., Jul 2013, In: British Journal of Dermatology. 169, Suppl. 1, p. 132 1 p., CD09.Research output: Contribution to journal › Meeting abstract › peer-review
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A multicentre parallel-group randomised trial assessing multiparametric MRI characterisation and image-guided biopsy of prostate in men suspected of having prostate cancer: MULTIPROS study protocol
Szewczyk-Bieda, M., Wei, C., Coll, K., Gandy, S., Donnan, P., Ragupathy, S. K. A., Singh, P., Wilson, J. & Nabi, G., 21 Nov 2019, In: Trials. 20, p. 1-8 8 p., 638.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)71 Downloads (Pure) -
A multi-centre, prospective epidemiological surveillance study considering ophthalmic complications of functional endoscopic sinus surgery
Burgess, S., Foulds, J., White, P., Foot, B. & Macewen, C., Mar 2020, In: Journal of Laryngology and Otology. 134, 3, p. 228-232 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)41 Downloads (Pure) -
A multi-centre, parallel group superiority trial of silk therapeutic clothing compared to standard care for the management of eczema in children (CLOTHES Trial): study protocol for a randomised controlled trial
Harrison, E. F., Haines, R. H., Cowdell, F., Sach, T. H., Dean, T., Pollock, I., Burrows, N. P., Buckley, H., Batchelor, J., Williams, H. C., Lawton, S., Brown, S. J., Bradshaw, L. E., Ahmed, A., Montgomery, A. A., Mitchell, E. J. & Thomas, K. S., 2 Sep 2015, In: Trials. 16, 12 p., 390.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)171 Downloads (Pure) -
A Multicenter, Randomized, Placebo-Controlled Trial of Atorvastatin for the Primary Prevention of Cardiovascular Events in Patients With Rheumatoid Arthritis: A multicenter, randomized, placebo controlled trial
Kitas, G. D., Nightingale, P., Armitage, J., Sattar, N., Belch, J. J. F. & Symmons, D. P. M., Sep 2019, In: Arthritis and Rheumatology. 71, 9, p. 1437-1449 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile30 Citations (Scopus)40 Downloads (Pure) -
A Multicellular Model of Intestinal Crypt Buckling and Fission
Almet, A. A., Hughes, B. D., Landman, K. A., Näthke, I. S. & Osborne, J. M., Feb 2018, In: Bulletin of Mathematical Biology. 80, 2, p. 335-359 25 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)226 Downloads (Pure) -
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure
LifeLines Cohort Study, Sung, Y. J., de Las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., Manning, A. K., Brown, M. R., Aschard, H., Feitosa, M. F., Franceschini, N., Lu, Y., Cheng, C-Y., Sim, X., Vojinovic, D. & 40 others, , 1 Aug 2019, In: Human Molecular Genetics. 28, 15, p. 2615-2633 19 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)61 Downloads (Pure) -
A multi-agent approach to modelling interaction in human mathematical reasoning
Pease, A., Colton, S., Smaill, A. & Lee, J., 2001, Intelligent Agent Technology : Research and Development - Proceedings of the 2nd Asia-Pacific Conference on IAT. Zhong, N., Liu, J., Ohsuga, S. & Bradshaw, J. (eds.). Singapore: World Scientific Publishing , p. 395-399 5 p.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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A MRI investigation of electroconvulsive therapy (ECT) for the treatment of depression
Perrin, J. S., Bennett, D. M., Currie, J., Steele, J. D. & Reid, I. C., Aug 2011, In: Journal of Psychopharmacology. 25, 8, p. A54-A54 1 p.Research output: Contribution to journal › Book/Film/Article review › peer-review
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Amputation-free survival in 17,353 people at high risk for foot ulceration in diabetes: a national observational study
Scottish Diabetes Research Network Epidemiology Group, Vadiveloo, T., Jeffcoate, W., Donnan, P. T., Colhoun, H. C., McGurnaghan, S., Wild, S., McCrimmon, R. & Leese, G. P., Dec 2018, In: Diabetologia. 61, 12, p. 2590-2597 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)188 Downloads (Pure) -
Amplified Hormonal Counterregulatory Responses to Hypoglycemia in Rats After Systemic Delivery of a SUR-1-Selective K+ Channel Opener?
Fan, X., Ding, Y., Cheng, H., Gram, D. X., Sherwin, R. S. & McCrimmon, R. J., Dec 2008, In: Diabetes. 57, 12, p. 3327-3334 8 p.Research output: Contribution to journal › Article › peer-review
10 Citations (Scopus) -
Amplified biochemical oscillations in cellular systems
McKane, A. J., Nagy, J. D., Newman, T. J. & Stefanini, M. O., Jul 2007, In: Journal of Statistical Physics. 128, 1-2, p. 165-191 27 p.Research output: Contribution to journal › Article › peer-review
75 Citations (Scopus) -
Amplification of seismic accelerations at slope crests
Brennan, A. J. & Madabhushi, S. P. G., May 2009, In: Canadian Geotechnical Journal. 46, 5, p. 585-594 10 p.Research output: Contribution to journal › Article › peer-review
21 Citations (Scopus) -
Amplification and increased expression of alpha class glutathione S-transferase-encoding genes associated with resistance to nitrogen mustards
Lewis, A. D., Hickson, I. D., Robson, C. N., Harris, A. L., Hayes, J. D., Griffiths, S. A., Manson, M. M., Hall, A. E., Moss, J. E. & Wolf, C. R., Nov 1988, In: Proceedings of the National Academy of Sciences of the United States of America. 85, 22, p. 8511-5 5 p.Research output: Contribution to journal › Article › peer-review
152 Citations (Scopus) -
AMPKα1: a glucose sensor that controls CD8 T-cell memory
Rolf, J., Zarrouk, M., Finlay, D. K., Foretz, M., Viollet, B. & Cantrell, D. A., Apr 2013, In: European Journal of Immunology. 43, 4, p. 889-896 8 p.Research output: Contribution to journal › Article › peer-review
133 Citations (Scopus) -
AMPK-sensing energy while talking to other signaling pathways
Hardie, D. G., 2 Dec 2014, In: Cell Metabolism. 20, 6, p. 939-952 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile311 Citations (Scopus)152 Downloads (Pure) -
AMPK promotes p53 acetylation via phosphorylation and inactivation of SIRT1 in liver cancer cells
Lee, C-W., Wong, L. L-Y., Tse, E. Y-T., Liu, H-F., Leong, V. Y-L., Lee, J. M-F., Hardie, D. G., Ng, I. O-L. & Ching, Y-P., 2012, In: Cancer Research. 72, 17, p. 4394-4404 11 p.Research output: Contribution to journal › Article › peer-review
131 Citations (Scopus) -
AMPK modulates glucose-sensing in insulin-secreting cells by altered phosphotransfer to KATP channels
Beall, C., Watterson, K. R., McCrimmon, R. J. & Ashford, M. L. J., Jun 2013, In: Journal of Bioenergetics and Biomembranes. 45, 3, p. 229-241 13 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons
Claret, M., Smith, M. A., Batterham, R. L., Selman, C., Choudhury, A. I., Fryer, L. G. D., Clements, M., Al-Qassab, H., Heffron, H., Xu, A. W., Speakman, J. R., Barsh, G. S., Viollet, B., Vaulont, S., Ashford, M. L. J., Carling, D. & Withers, D. J., Aug 2007, In: Journal of Clinical Investigation. 117, 8, p. 2325-2336 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile362 Citations (Scopus)187 Downloads (Pure) -
AMPK dilates resistance arteries via activation of SERCA and BKCa channels in smooth muscle
Schneider, H., Schubert, K. M., Blodow, S., Kreutz, C-P., Erdogmus, S., Wiedenmann, M., Qiu, J., Fey, T., Ruth, P., Lubomirov, L. T., Pfitzer, G., Mederos y Schnitzler, M., Hardie, D. G., Gudermann, T. & Pohl, U., Jul 2015, In: Hypertension. 66, 1, p. 108-116 9 p.Research output: Contribution to journal › Article › peer-review
30 Citations (Scopus) -
AMPK Causes Cell Cycle Arrest in LKB1-deficient Cells via Activation of CAMKK2
Fogarty, S., Ross, F. A., Vara Ciruelos, D., Gray, A., Gowans, G. J. & Hardie, D. G., 1 Aug 2016, In: Molecular Cancer Research. 14, 8, p. 683-695 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile34 Citations (Scopus)311 Downloads (Pure) -
AMPK as a direct sensor of long-chain fatty acyl–CoA esters
Hardie, D. G., 27 Jul 2020, In: Nature Metabolism.Research output: Contribution to journal › Comment/debate › peer-review
Open AccessFile1 Citation (Scopus)6 Downloads (Pure) -
AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B
Johanns, M., Lai, Y. C., Hsu, M. F., Jacobs, R., Vertommen, D., Van Sande, J., Dumont, J. E., Woods, A., Carling, D., Hue, L., Viollet, B., Foretz, M. & Rider, M. H., 8 Mar 2016, In: Nature Communications. 7, 10856.Research output: Contribution to journal › Article › peer-review
Open Access54 Citations (Scopus) -
AMPK and TOR: the Yin and Yang of cellular nutrient sensing and growth control
González, A., Hall, M. N., Lin, S-C. & Hardie, G., 3 Mar 2020, In: Cell Metabolism. 31, 3, p. 472-492 21 p.Research output: Contribution to journal › Review article › peer-review
23 Citations (Scopus) -
AMPK and the Need to Breathe and Feed: What's the Matter with Oxygen?
Evans, A. M. & Hardie, D. G., 15 May 2020, In: International Journal of Molecular Sciences. 21, 10, p. 1-28 28 p., 3518.Research output: Contribution to journal › Review article › peer-review
Open AccessFile -
AMPK and SNF1: snuffing out stress
Hardie, D. G., 7 Nov 2007, In: Cell Metabolism. 6, 5, p. 339-40 2 p.Research output: Contribution to journal › Article › peer-review
36 Citations (Scopus) -
AMPK and raptor: matching cell growth to energy supply
Hardie, D. G., 9 May 2008, In: Molecular Cell. 30, 3, p. 263-265 3 p.Research output: Contribution to journal › Editorial › peer-review
93 Citations (Scopus) -
AMPK and autophagy get connected
Hardie, D. G., 16 Feb 2011, In: EMBO Journal. 30, 4, p. 634-635 2 p.Research output: Contribution to journal › Editorial › peer-review
118 Citations (Scopus) -
AMPK activators inhibit the proliferation of human melanomas bearing the activated MAPK pathway
Petti, C., Vegetti, C., Molla, A., Bersani, I., Cleris, L., Mustard, K. J., Formelli, F., Hardie, G. D., Sensi, M. & Anichini, A., 2012, In: Melanoma Research. 22, 5, p. 341-350 10 p.Research output: Contribution to journal › Article › peer-review
34 Citations (Scopus) -
AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1-Parkin independent manner
Seabright, A. P., Fine, N. H. F., Barlow, J. P., Lord, S. O., Musa, I., Gray, A., Bryant, J. A., Banzhaf, M., Lavery, G. G., Hardie, D. G., Hodson, D. J., Philp, A. & Lai, Y-C., 4 May 2020, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34, 5, p. 6284-6301 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)77 Downloads (Pure) -
AMPK: opposing the metabolic changes in both tumour cells and inflammatory cells?
Dandapani, M. & Hardie, D. G., Apr 2013, In: Biochemical Society Transactions. 41, 2, p. 687-693 7 p.Research output: Contribution to journal › Article › peer-review
34 Citations (Scopus) -
AMPK: positive and negative regulation, and its role in whole-body energy homeostasis
Hardie, D. G., Apr 2015, In: Current Opinion in Cell Biology. 33, April, p. 1-7 7 p.Research output: Contribution to journal › Review article › peer-review
266 Citations (Scopus) -
AMPK: a target for drugs and natural products with effects on both diabetes and cancer
Hardie, D. G., Jul 2013, In: Diabetes. 62, 7, p. 2164-2172 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile263 Citations (Scopus)133 Downloads (Pure) -
AMPK: Sensing Glucose as well as Cellular Energy Status
Lin, S-C. & Hardie, D., 6 Feb 2018, In: Cell Metabolism. 27, 2, p. 299-313 15 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile226 Citations (Scopus)389 Downloads (Pure) -
AMPK: a cellular energy sensor primarily regulated by AMP
Gowans, G. J. & Hardie, D. G., 1 Feb 2014, In: Biochemical Society Transactions. 42, 1, p. 71-75 5 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile74 Citations (Scopus)168 Downloads (Pure) -
AMPK: a key regulator of energy balance in the single cell and the whole organism
Hardie, D. G., Sep 2008, In: International Journal of Obesity. 32, p. S7-S12 6 p.Research output: Contribution to journal › Article › peer-review
470 Citations (Scopus) -
AMPK: mediating the metabolic effects of salicylate-based drugs?
Steinberg, G. R., Dandapani, M. & Hardie, D. G., Oct 2013, In: Trends in Endocrinology and Metabolism. 24, 10, p. 481-487 7 p.Research output: Contribution to journal › Review article › peer-review
50 Citations (Scopus) -
AMPK: regulating energy balance at the cellular and whole body levels
Hardie, D. G. & Ashford, M. L. J., Mar 2014, In: Physiology. 29, 2, p. 99-107 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile161 Citations (Scopus)160 Downloads (Pure) -
AMPK: a nutrient and energy sensor that maintains energy homeostasis
Hardie, D. G., Ross, F. A. & Hawley, S. A., 1 Apr 2012, In: Nature Reviews Molecular Cell Biology. 13, 4, p. 251-262 12 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile2176 Citations (Scopus)236 Downloads (Pure) -
AMPK: an energy-sensing pathway with multiple inputs and outputs
Hardie, D. G., Schaffer, B. E. & Brunet, A., Mar 2016, In: Trends in Cell Biology. 26, 3, p. 190-201 12 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile363 Citations (Scopus)351 Downloads (Pure) -
AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation
Gowans, G. J., Hawley, S. A., Ross, F. A. & Hardie, D. G., 1 Oct 2013, In: Cell Metabolism. 18, 4, p. 556-566 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile272 Citations (Scopus)159 Downloads (Pure)