Find Research Outputs

Search concepts
Selected filters
2011

Fermentation in the human large intestine: its physiologic consequences and the potential contribution of prebiotics

Macfarlane, G. T. & Macfarlane, S., 2011, In : Journal of Clinical Gastroenterology. 45, p. S120-S127 8 p.

Research output: Contribution to journalArticle

200 Citations (Scopus)
2008

Bacterial metabolism and health-related effects of galacto-oligosaccharides and other prebiotics

Macfarlane, G. T., Steed, H. & Macfarlane, S., Feb 2008, In : Journal of Applied Microbiology. 104, 2, p. 305-344 40 p.

Research output: Contribution to journalReview article

460 Citations (Scopus)

Network pharmacology: the next paradigm in drug discovery

Hopkins, A. L., Nov 2008, In : Nature Chemical Biology. 4, 11, p. 682-690 9 p.

Research output: Contribution to journalReview article

1629 Citations (Scopus)
2012

Quantifying the chemical beauty of drugs

Bickerton, G. R., Paolini, G. V., Besnard, J., Muresan, S. & Hopkins, A. L., Feb 2012, In : Nature Chemistry. 4, 2, p. 90-98 9 p.

Research output: Contribution to journalArticle

362 Citations (Scopus)
2009

The European Surveillance of Antimicrobial Consumption (ESAC) Point-Prevalence Survey of Antibacterial Use in 20 European Hospitals in 2006

Ansari, F., Erntell, M., Goossens, H., Davey, P. & ESAC II Hosp Care Study Grp, 15 Nov 2009, In : Clinical Infectious Diseases. 49, 10, p. 1496-1504 9 p.

Research output: Contribution to journalArticle

140 Citations (Scopus)

The ethanolamine branch of the Kennedy pathway is essential in the bloodstream form of Trypanosoma brucei

Gibellini, F., Hunter, W. N. & Smith, T. K., Sep 2009, In : Molecular Microbiology. 73, 5, p. 826-843 18 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)
2011

Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2

Deng, X., Dzamko, N., Prescott, A., Davies, P., Liu, Q., Yang, Q., Lee, J-D., Patricelli, M. P., Nomanbhoy, T. K., Alessi, D. R. & Gray, N. S., Apr 2011, In : Nature Chemical Biology. 7, 4, p. 203-205 3 p.

Research output: Contribution to journalArticle

244 Citations (Scopus)
2008

A prospective clinical study of periradicular surgery using mineral trioxide aggregate as a root-end filling

Saunders, W. P., Jun 2008, In : Journal of Endodontics. 34, 6, p. 660-665 6 p.

Research output: Contribution to journalArticle

109 Citations (Scopus)
2010

Normalisation process theory: a framework for developing, evaluating and implementing complex interventions

Murray, E., Treweek, S., Pope, C., MacFarlane, A., Ballini, L., Dowrick, C., Finch, T., Kennedy, A., Mair, F., O'Donnell, C., Ong, B. N., Rapley, T., Rogers, A. & May, C., 20 Oct 2010, In : BMC Medicine. 8, p. - 11 p., 63.

Research output: Contribution to journalComment/debate

Open Access
File
310 Citations (Scopus)
114 Downloads (Pure)
2009

Angiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathway

San-Cristobal, P., Pacheco-Alvarez, D., Richardson, C., Ring, A. M., Vazquez, N., Rafiqi, F. H., Chari, D., Kahle, K. T., Leng, Q., Bobadilla, N. A., Hebert, S. C., Alessi, D. R., Lifton, R. P. & Gamba, G., 17 Mar 2009, In : Proceedings of the National Academy of Sciences of the United States of America. 106, 11, p. 4384-4389 6 p.

Research output: Contribution to journalArticle

182 Citations (Scopus)
2011

Staff regard towards working with substance users: a European multi-centre study

Gilchrist, G., Moskalewicz, J., Slezakova, S., Okruhlica, L., Torrens, M., Vajd, R. & Baldacchino, A., Jun 2011, In : Addiction. 106, 6, p. 1114-1125 12 p.

Research output: Contribution to journalArticle

76 Citations (Scopus)
2010

Bioinformatic and experimental survey of 14-3-3-binding sites

Johnson, C., Crowther, S., Stafford, M. J., Campbell, D. G., Toth, R. & MacKintosh, C., 1 Apr 2010, In : Biochemical Journal. 427, 1, p. 69-78 10 p.

Research output: Contribution to journalArticle

172 Citations (Scopus)
2009

Differential 14-3-3 affinity capture reveals new downstream targets of Phosphatidylinositol 3-Kinase signaling

Dubois, F., Vandermoere, F., Gernez, A., Murphy, J., Toth, R., Chen, S., Geraghty, K. M., Morrice, N. A. & MacKintosh, C., Nov 2009, In : Molecular & Cellular Proteomics. 8, 11, p. 2487-2499 13 p.

Research output: Contribution to journalArticle

52 Citations (Scopus)
2008

Spatial Reasoning With External Visualizations: What Matters Is What You See, Not Whether You Interact

Keehner, M., Hegarty, M., Cohen, C., Khooshabeh, P. & Montello, D. R., 2008, In : Cognitive Science. 32, 7, p. 1099-1132 34 p.

Research output: Contribution to journalArticle

100 Citations (Scopus)
2011

Finger counting habits in Middle Eastern and Western individuals: An online survey

Lindemann, O., Alipour, A. & Fischer, M. H., May 2011, In : Journal of Cross-Cultural Psychology. 42, 4, p. 566-578 13 p.

Research output: Contribution to journalArticle

76 Citations (Scopus)
2009

Reading habits for both words and numbers contribute to the SNARC effect

Shaki, S., Fischer, M. H. & Petrusic, W. M., Apr 2009, In : Psychonomic Bulletin & Review. 16, 2, p. 328-331 4 p.

Research output: Contribution to journalArticle

260 Citations (Scopus)
2008

Mental movements without magnitude? A study of spatial biases in symbolic arithmetic

Pinhas, M. & Fischer, M. H., Dec 2008, In : Cognition. 109, 3, p. 408-415 8 p.

Research output: Contribution to journalArticle

109 Citations (Scopus)

The roles of long-chain polyunsaturated fatty acids in pregnancy, lactation and infancy: review of current knowledge and consensus recommendations

Koletzko, B., Lien, E., Agostoni, C., Boehles, H., Campoy, C., Cetin, I., Decsi, T., Dudenhausen, J. W., Dupont, C., Forsyth, S., Hoesli, I., Holzgreve, W., Lapillonne, A., Putet, G., Secher, N. J., Symonds, M., Szajewska, H., Willatts, P. & Uauy, R., 2008, In : Journal of Perinatal Medicine. 36, 1, p. 5-14 10 p.

Research output: Contribution to journalArticle

473 Citations (Scopus)
2010

The nuts and bolts of AGC protein kinases

Pearce, L. R., Komander, D. & Alessi, D. R., Jan 2010, In : Nature Reviews Molecular Cell Biology. 11, 1, p. 9-22 14 p.

Research output: Contribution to journalReview article

812 Citations (Scopus)
2008

Improving the reporting of pragmatic trials: an extension of the CONSORT statement

Zwarenstein, M., Treweek, S., Gagnier, J. J., Altman, D. G., Tunis, S., Haynes, B., Oxman, A. D., Moher, D. & CONSORT Grp, Pragmatic Trials Healthcare Practi, 11 Nov 2008, In : BMJ. 337, p. - 12 p., a2390.

Research output: Contribution to journalArticle

899 Citations (Scopus)
2011

Characterization of GSK2334470, a novel and highly specific inhibitor of PDK1

Najafov, A., Sommer, E. M., Axten, J. M., DeYoung, M. P. & Alessi, D. R., 15 Jan 2011, In : Biochemical Journal. 433, p. 357-369 13 p.

Research output: Contribution to journalArticle

93 Citations (Scopus)
2008

Reading space into numbers - a cross-linguistic comparison of the SNARC effect

Shaki, S. & Fischer, M. H., Aug 2008, In : Cognition. 108, 2, p. 590-599 10 p.

Research output: Contribution to journalArticle

135 Citations (Scopus)

Finger counting habits modulate spatial-numerical associations

Fischer, M. H., Apr 2008, In : Cortex. 44, 4, p. 386-392 7 p.

Research output: Contribution to journalArticle

154 Citations (Scopus)

Small-molecule inhibitors of PDK1

Peifer, C. & Alessi, D. R., 15 Dec 2008, In : ChemMedChem. 3, 12, p. 1810-1838 29 p.

Research output: Contribution to journalReview article

98 Citations (Scopus)

How to cook a SNARC: number placement in text changes spatial-numerical associations

Fischer, M. & Mills, R., 2008, In : International Journal of Psychology. 43, 3-4, p. 672-672 1 p.

Research output: Contribution to journalMeeting abstract

2009

Studying the infant feeding intentions of pregnant women experiencing material deprivation: methodology of the Looking at Infant Feeding Today (LIFT) study

McMillan, B., Green, J. M., Woolridge, M. W., Dyson, L., Renfrew, M. J. & Clarke, G. P., 2009, In : Social Science and Medicine. 68, 5, p. 845-9 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)
2005

Interventions for promoting the initiation of breastfeeding

Dyson, L., McCormick, F. & Renfrew, M. J., 2005, In : Cochrane Database of Systematic Reviews. 2, p. CD001688

Research output: Contribution to journalArticle

196 Citations (Scopus)
2000

Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins

Zhou, X. Z., Kops, O., Werner, A., Lu, P-J., Shen, M., Stoller, G., Kullertz, G., Stark, M., Fischer, G. & Lu, K. P., 2000, In : Molecular Cell. 6, 4, p. 873-883 11 p.

Research output: Contribution to journalArticle

445 Citations (Scopus)
1998

Mass spectrometric analysis of the anaphase-promoting complex from yeast: Identification of a subunit related to cullins

Zachariae, W., Shevchenko, A., Andrews, P. D., Ciosk, R., Galova, M., Stark, M. J. R., Mann, M. & Nasmyth, K., 1998, In : Science. 279, 5354, p. 1216-1219 4 p.

Research output: Contribution to journalArticle

284 Citations (Scopus)
2000
479 Citations (Scopus)
2012

Automated design of ligands to polypharmacological profiles

Besnard, J., Ruda, G. F., Setola, V., Abecassis, K., Rodriguiz, R. M., Huang, X-P., Norval, S., Sassano, M. F., Shin, A. I., Webster, L. A., Simeons, F. R. C., Stojanovski, L., Prat, A., Seidah, N. G., Constam, D. B., Bickerton, G. R., Read, K. D., Wetsel, W. C., Gilbert, I. H., Roth, B. L. & 1 others, Hopkins, A. L., 13 Dec 2012, In : Nature. 492, 7428, p. 215-+ 8 p.

Research output: Contribution to journalArticle

404 Citations (Scopus)

An hnRNP-like RNA-binding protein affects alternative splicing by in vivo interaction with transcripts in Arabidopsis thaliana

Streitner, C., Köster, T., Simpson, C. G., Shaw, P., Danisman, S., Brown, J. W. S. & Staiger, D., Dec 2012, In : Nucleic Acids Research. 40, 22, p. 11240-11255 16 p.

Research output: Contribution to journalArticle

69 Citations (Scopus)
2005

Global analysis of protein phosphorylation in yeast

Ptacek, J., Devgan, G., Michaud, G., Zhu, H., Zhu, X., Fasolo, J., Guo, H., Jona, G., Breitkreutz, A., Sopko, R., McCartney, R. R., Schmidt, M. C., Rachidi, N., Lee, S-J., Mah, A. S., Meng, L., Stark, M. J. R., Stern, D. F., De Virgilio, C., Tyers, M. & 5 others, Andrews, B., Gerstein, M., Schweitzer, B., Predki, P. F. & Snyder, M., 1 Dec 2005, In : Nature. 438, 7068, p. 679-684 6 p.

Research output: Contribution to journalLetter

759 Citations (Scopus)
1994

Gastric mucosal bleeding time in cirrhosis

Jalan, R., Grose, R., Dillon, J. F., Simpson, K. & Hayes, P. C., 1994, In : Gastrointestinal Endoscopy. 40, 5, p. 599-602 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2012

Support for healthy breastfeeding mothers with healthy term babies

Renfrew, M. J., McCormick, F. M., Wade, A., Quinn, B. & Dowswell, T., 16 May 2012, In : Cochrane Database of Systematic Reviews. 2012, 5, 206 p., CD001141.

Research output: Contribution to journalArticle

291 Citations (Scopus)

A physical, genetic and functional sequence assembly of the barley genome

Mayer, K. F. X., Waugh, R., Brown, J. W. S., Schulman, A., Langridge, P., Platzer, M., Fincher, G. B., Muehlbauer, G. J., Sato, K., Close, T. J., Wise, R. P., Stein, N. & International Barley Genome Sequencing Consortium, 29 Nov 2012, In : Nature. 491, 7426, p. 711-716 6 p.

Research output: Contribution to journalArticle

930 Citations (Scopus)
2002

The glycan core of GPI-anchored proteins modulates aerolysin binding but is not sufficient: the polypeptide moiety is required for the toxin-receptor interaction

Abrami, L., Velluz, M-C., Hong, Y. J., Ohishi, K., Mehlert, A., Ferguson, M., Kinoshita, T. & van der Goot, F. G., 13 Feb 2002, In : FEBS Letters. 512, 1-3, p. 249-254 6 p.

Research output: Contribution to journalArticle

39 Citations (Scopus)
2011

Differences in p63 expression in SCCHN tumours of different sub-sites within the oral cavity

Boldrup, L., Coates, P. J., Laurell, G. & Nylander, K., 2011, In : Oral Oncology. 47, 9, p. 861-865 5 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)
2002

Impact of aldosterone on vascular pathophysiology

Struthers, A. D., 2002, In : Congestive Heart Failure . 8, 1, p. 18-22 5 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)
2004

Study of agreement between LDL size as measured by nuclear magnetic resonance and gradient gel electrophoresis

Witte, D. R., Taskinen, M. R., Perttunen-Nio, H., Van Tol, A., Livingstone, S. & Colhoun, H. M., Jun 2004, In : Journal of Lipid Research. 45, 6, p. 1069-76 8 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)
2000

The effect of type 1 diabetes mellitus on the gender difference in coronary artery calcification

Colhoun, H. M., Rubens, M. B., Underwood, S. R. & Fuller, J. H., Dec 2000, In : Journal of the American College of Cardiology. 36, 7, p. 2160-2167 8 p.

Research output: Contribution to journalArticle

112 Citations (Scopus)
2006

A randomized controlled trial of Sweet Talk: a text-messaging system to support young people with diabetes

Franklin, V. L., Waller, A., Pagliari, C. & Greene, S. A., 1 Dec 2006, In : Diabetic Medicine. 23, 12, p. 1332-1338 7 p.

Research output: Contribution to journalArticle

389 Citations (Scopus)
2013

Automatic fovea location in retinal images using anatomical priors and vessel density

Chin, K. S., Trucco, E., Tan, L. & Wilson, P. J., 15 Jul 2013, In : Pattern Recognition Letters. 34, 10, p. 1152-1158 7 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Dysfunctional astrocytic and synaptic regulation of hypothalamic glutamatergic transmission in a mouse model of early-life adversity: relevance to neurosteroids and programming of the stress-response.

Gunn, B., Cunningham, L., Cooper, M. A., Corteen, N., Seifi, M., Swinny, J. D., Lambert, J. J. & Belelli, D., 11 Dec 2013, In : Journal of Neuroscience. 33, 50, p. 19534-19554 21 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)
2015

Situational ethics: re-thinking approaches to formal ethics requirements for Human-Computer Interaction

Munteanu, C., Molyneaux, H., Moncur, W., Romero, M., O'Donnell, S. & Vines, J., Apr 2015, CHI 2015: proceedings of the 33rd Annual CHI Conference on Human Factors in Computing Systems. New York: Association for Computing Machinery, p. 105-114 10 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

38 Citations (Scopus)
2013
Open Access
2 Citations (Scopus)
107 Citations (Scopus)
2008

A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes

Wilkinson, S. R., Taylor, M. C., Horn, D., Kelly, J. M. & Cheeseman, I., 1 Apr 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 13, p. 5022-5027 6 p.

Research output: Contribution to journalArticle

263 Citations (Scopus)
2010

In situ wavefront correction and its application to micromanipulation

Cizmar, T., Mazilu, M. & Dholakia, K., Jun 2010, In : Nature Photonics. 4, 6, p. 388-394 7 p.

Research output: Contribution to journalArticle

311 Citations (Scopus)
2013

DNA break site at fragile subtelomeres determines probability and mechanism of antigenic variation in African trypanosomes

Glover, L., Alsford, S. & Horn, D., Mar 2013, In : PLoS Pathogens. 9, 3, 15 p., ARTN e1003260.

Research output: Contribution to journalArticle

47 Citations (Scopus)