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Review article

Activation of protein kinase B β and γ isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: Comparison with protein kinase B α

Walker, K. S., Deak, M., Paterson, A., Hudson, K., Cohen, P. & Alessi, D. R., 1 Apr 1998, In : Biochemical Journal. 331, 1, p. 299-308 10 p.

Research output: Contribution to journalReview article

230 Citations (Scopus)

Acute effects of weight training on glycaemia in type 1 diabetes

Chisholm, J., Kilbride, L., Charlton, J. & McKnight, J. A., 1 May 2012, In : Practical Diabetes International. 29, 4, p. 155–159 5 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Acute risk factors in fatal opioid overdoses as a result of hypoxia and cardiotoxicity. A systematic review and critical appraisal

Baldacchino, A., Tolomeo, S., Khan, F., Humphris, G. & Carrà, G., Aug 2016, In : Heroin Addiction and Related Clinical Problems. 18, 4, p. 33-42 10 p.

Research output: Contribution to journalReview article

1 Citation (Scopus)

Adaptation and therapeutic exploitation of the plasma membrane of African trypanosomes

Quintana, J. F., Canavate Del Pino, R., Yamada, K., Zhang, N. & Field, M., 20 Jul 2018, In : Genes. 9, 7, 16 p., 368.

Research output: Contribution to journalReview article

Open Access
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2 Citations (Scopus)
159 Downloads (Pure)

ADHD in children and young people: prevalence, care pathways, and service provision

Sayal, K., Prasad, V., Daley, D., Ford, T. & Coghill, D., Feb 2018, In : Lancet Psychiatry. 5, 2, p. 175-186 12 p.

Research output: Contribution to journalReview article

87 Citations (Scopus)

Adhesive precoated bracket systems and operator coated bracket systems: Is there any difference? A systematic review and meta-analysis

Alakttash, A. M., Mohamed, F. & Bearn, D., May 2019, In : Angle Orthodontist. 89, 3, p. 495-504 10 p.

Research output: Contribution to journalReview article

Open Access
File
1 Citation (Scopus)
76 Downloads (Pure)

Adiponectin in childhood

Jeffery, A. N., Murphy, M. J., Metcalf, B. S., Hosking, J., Voss, L. D., English, P., Sattar, N. & Wilkin, T. J., 2008, In : International Journal of Pediatric Obesity. 3, 3, p. 130-140 11 p.

Research output: Contribution to journalReview article

40 Citations (Scopus)

Adjunctive tests cannot replace scalpel biopsy for oral cancer diagnosis

Richards, D., Jun 2015, In : Evidence-Based Dentistry. 16, 2, p. 46-47 2 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)

Advances in bacterial transcriptome and transposon insertion-site profiling using second-generation sequencing

Febrer, M., McLay, K., Caccamo, M., Twomey, K. B. & Ryan, R. . P., 1 Nov 2011, In : Trends in Biotechnology. 29, 11, p. 586-594 9 p.

Research output: Contribution to journalReview article

18 Citations (Scopus)

Advances in bronchiectasis: endotyping, genetics, microbiome, and disease heterogeneity

Flume, P. A., Chalmers, J. D. & Olivier, K. N., 8 Sep 2018, In : The Lancet. 392, 10150, p. 880-890 11 p.

Research output: Contribution to journalReview article

Open Access
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44 Citations (Scopus)
232 Downloads (Pure)

Advances in targeted degradation of endogenous proteins

Roth, S., Fulcher, L. & Sapkota, G., 27 Apr 2019, In : Cellular and Molecular Life Sciences. 76, 14, p. 2761-2777 17 p.

Research output: Contribution to journalReview article

Open Access
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9 Citations (Scopus)
386 Downloads (Pure)

Adverse effects of pharmacotherapies for attention-deficit hyperactivity disorder - Epidemiology, prevention and management

Graham, J. & Coghill, D., 2008, In : CNS Drugs. 22, 3, p. 213-237 25 p.

Research output: Contribution to journalReview article

118 Citations (Scopus)

Adverse effects of topical photodynamic therapy

Ibbotson, S. H., Jun 2011, In : Photodermatology, Photoimmunology & Photomedicine. 27, 3, p. 116-130 15 p.

Research output: Contribution to journalReview article

53 Citations (Scopus)

A European's perspective of COX-2 drug safety

MacDonald, T. M., Jun 2006, In : Journal of Cardiovascular Pharmacology. 47, SUPPL. 1, p. S92-S97

Research output: Contribution to journalReview article

Afferent and spinal mechanisms of joint pain

Schaible, H. G. & Grubb, B. D., 1 Oct 1993, In : Pain. 55, 1, p. 5-54 50 p.

Research output: Contribution to journalReview article

467 Citations (Scopus)

Affinity methods for phosphorylation-dependent interactions.

Moorhead, G. & MacKintosh, C., 1 Jan 2004, In : Methods in Molecular Biology (Clifton, N.J.). 261, p. 469-478 10 p.

Research output: Contribution to journalReview article

4 Citations (Scopus)
Open Access
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110 Citations (Scopus)
188 Downloads (Pure)

Ageing and vitamin D deficiency: effects on calcium homeostasis and considerations for vitamin D supplementation

Oudshoom, C., van der Cammen, T. J. M., McMurdo, M. E. T., van Leeuwen, J. P. T. M. & Colin, E. M., 14 Jun 2009, In : British Journal of Nutrition. 101, 11, p. 1597-1606 10 p.

Research output: Contribution to journalReview article

31 Citations (Scopus)

A gradient signal orchestrates the mitotic spindle

Clarke, P. R., 26 Aug 2005, In : Science. 309, 5739, p. 1334-1335 2 p.

Research output: Contribution to journalReview article

16 Citations (Scopus)

A holistic food labelling strategy for preventing obesity and dental caries: Viewpoint

Cinar, A. B. & Murtomaa, H., May 2009, In : Obesity Reviews. 10, 3, p. 357-361 5 p.

Research output: Contribution to journalReview article

9 Citations (Scopus)

A key role for the GINS complex at DNA replication forks

Labib, K. & Gambus, A., Jun 2007, In : Trends in Cell Biology. 17, 6, p. 271-278 8 p.

Research output: Contribution to journalReview article

93 Citations (Scopus)

Alcohol screening and assessment measures for young people: A systematic review and meta-analysis of validation studies

Toner, P., Böhnke, J., Anderson, P. & McCambridge, J., 1 Sep 2019, In : Drug and Alcohol Dependence. 202, p. 39-49 11 p.

Research output: Contribution to journalReview article

Open Access
File
1 Citation (Scopus)
94 Downloads (Pure)

Aldosterone antagonism in type 2 diabetes mellitus: a new therapeutic approach to diabetic macrovascular disease?

Swaminathan, K., Davies, J. & Struthers, A., 1 Jan 2008, In : British Journal of Diabetes and Vascular Disease. 8, 1, p. 16-19 4 p.

Research output: Contribution to journalReview article

Altered calcium regulation in freshly isolated aortic smooth muscle cells from bile duct-ligated rats: Role of nitric oxide

Atucha, N. M., Iyu, D., De Rycker, M., Soler, A. & García-Estañ, J., Feb 2003, In : Cell Calcium. 33, 2, p. 129-135 7 p.

Research output: Contribution to journalReview article

16 Citations (Scopus)

Ambient Assisted Living Technologies for Aging Well: A Scoping Review

Blackman, S., Matlo, C., Bobrovitskiy, C., Waldoch, A., Fang, M. L., Jackson, P., Mihailidis, A., Nygård, L., Astell, A. & Sixsmith, A., Jan 2016, In : Journal of Intelligent Systems. 25, 1, p. 55-69 15 p.

Research output: Contribution to journalReview article

72 Citations (Scopus)

Ambiente e genetica nell'eziologia delle labioschisi e palatoschisi con particolare riferimento al ruolo dell'acido folico.

Translated title of the contribution: Environment and genetics in the etiology of cleft lip and cleft palate with reference to the role of folic acidBianchi, F., Calzolari, E., Ciulli, L., Cordier, S., Gualandi, F., Pierini, A. & Mossey, P., 1 Jan 2000, In : Epidemiologia e prevenzione. 24, 1, p. 21-27 7 p.

Research output: Contribution to journalReview article

26 Citations (Scopus)

Ambulatory blood pressure monitoring in hypertension

Prasad, N., Macfadyen, R. J. & Macdonald, T. M., Feb 1996, In : QJM - Monthly Journal of the Association of Physicians. 89, 2, p. 95-102 8 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)

Amfetamine and methylphenidate medications for attention-deficit/hyperactivity disorder: complementary treatment options

Hodgkins, P., Shaw, M., Coghill, D., Hechtman, L. & Coghill, D., 2012, In : European Child & Adolescent Psychiatry. 21, 9, p. 477-492 16 p.

Research output: Contribution to journalReview article

65 Citations (Scopus)

Amino acid transceptors: gate keepers of nutrient exchange and regulators of nutrient signaling

Hundal, H. S. & Taylor, P. M., Apr 2009, In : American Journal of Physiology, Endocrinology and Metabolism. 296, 4, p. E603-E613 11 p.

Research output: Contribution to journalReview article

198 Citations (Scopus)

AMP-activated protein kinase: a sensor of glycogen as well as AMP and ATP?

McBride, A. & Hardie, D. G., May 2009, In : Acta Physiologica. 196, 1, p. 99-113 15 p.

Research output: Contribution to journalReview article

87 Citations (Scopus)

AMP-activated protein kinase: also regulated by ADP?

Hardie, D. G., Carling, D. & Gamblin, S. J., Sep 2011, In : Trends in Biochemical Sciences. 36, 9, p. 470-477 8 p.

Research output: Contribution to journalReview article

115 Citations (Scopus)

AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function

Hardie, D. G., 15 Sep 2011, In : Genes & Development. 25, 18, p. 1895-1908 14 p.

Research output: Contribution to journalReview article

913 Citations (Scopus)

AMP-activated protein kinase: a key regulator of energy balance with many roles in human disease

Hardie, D. G., Dec 2014, In : Journal of Internal Medicine. 276, 6, p. 543-559 17 p.

Research output: Contribution to journalReview article

Open Access
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148 Citations (Scopus)
141 Downloads (Pure)

AMP-Activated Protein Kinase: A Target for Drugs both Ancient and Modern

Hardie, D. G., Ross, F. A. & Hawley, S. A., 26 Oct 2012, In : Chemistry & Biology. 19, 10, p. 1222-36 15 p.

Research output: Contribution to journalReview article

Open Access
File
242 Citations (Scopus)
143 Downloads (Pure)

AMP-Activated Protein Kinase: Maintaining Energy Homeostasis at the Cellular and Whole-Body Levels

Hardie, D. G., Jul 2014, In : Annual Review of Nutrition. 34, p. 31-55 25 p.

Research output: Contribution to journalReview article

110 Citations (Scopus)

AMP-Activated Protein Kinase: Friend or Foe in Cancer

Vara-ciruelos, D., Dandapani, M. & Hardie, D. G., 4 Mar 2020, In : Annual Review of Cancer Biology. 4, p. 1-16 16 p.

Research output: Contribution to journalReview article

Open Access
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22 Downloads (Pure)

AMP-Activated Protein Kinase: An Ubiquitous Signaling Pathway With Key Roles in the Cardiovascular System

Salt, I. P. & Hardie, D. G., 26 May 2017, In : Circulation Research. 120, 11, p. 1825-1841 17 p.

Research output: Contribution to journalReview article

Open Access
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57 Citations (Scopus)
113 Downloads (Pure)

AMP-activated protein kinase - not just an energy sensor

Hardie, D. G. & Lin, S-C., 22 Sep 2017, In : F1000 Research. 6, p. 1-11 11 p., 1724.

Research output: Contribution to journalReview article

Open Access
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35 Citations (Scopus)
159 Downloads (Pure)

AMP-activated protein kinase pathway: a potential therapeutic target in cardiometabolic disease

Wong, A. K. F., Howie, J., Petrie, J. R. & Lang, C. C., Apr 2009, In : Clinical and Translational Science. 116, 7-8, p. 607-620 14 p.

Research output: Contribution to journalReview article

117 Citations (Scopus)

AMPK: Sensing Glucose as well as Cellular Energy Status

Lin, S-C. & Hardie, D., 6 Feb 2018, In : Cell Metabolism. 27, 2, p. 299-313 15 p.

Research output: Contribution to journalReview article

Open Access
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180 Citations (Scopus)
323 Downloads (Pure)

AMPK: positive and negative regulation, and its role in whole-body energy homeostasis

Hardie, D. G., Apr 2015, In : Current Opinion in Cell Biology. 33, April, p. 1-7 7 p.

Research output: Contribution to journalReview article

249 Citations (Scopus)

AMPK: an energy-sensing pathway with multiple inputs and outputs

Hardie, D. G., Schaffer, B. E. & Brunet, A., Mar 2016, In : Trends in Cell Biology. 26, 3, p. 190-201 12 p.

Research output: Contribution to journalReview article

Open Access
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314 Citations (Scopus)
324 Downloads (Pure)

AMPK: a cellular energy sensor primarily regulated by AMP

Gowans, G. J. & Hardie, D. G., 1 Feb 2014, In : Biochemical Society Transactions. 42, 1, p. 71-75 5 p.

Research output: Contribution to journalReview article

Open Access
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63 Citations (Scopus)
140 Downloads (Pure)

AMPK: a nutrient and energy sensor that maintains energy homeostasis

Hardie, D. G., Ross, F. A. & Hawley, S. A., 1 Apr 2012, In : Nature Reviews Molecular Cell Biology. 13, 4, p. 251-262 12 p.

Research output: Contribution to journalReview article

Open Access
File
2018 Citations (Scopus)
193 Downloads (Pure)

AMPK: mediating the metabolic effects of salicylate-based drugs?

Steinberg, G. R., Dandapani, M. & Hardie, D. G., Oct 2013, In : Trends in Endocrinology and Metabolism. 24, 10, p. 481-487 7 p.

Research output: Contribution to journalReview article

46 Citations (Scopus)

AMPK and the Need to Breathe and Feed: What's the Matter with Oxygen?

Evans, A. M. & Hardie, D. G., 15 May 2020, In : International Journal of Molecular Sciences. 21, 10, p. 1-28 28 p., 3518.

Research output: Contribution to journalReview article

Open Access
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16 Downloads (Pure)

AMPK and TOR: the Yin and Yang of cellular nutrient sensing and growth control

González, A., Hall, M. N., Lin, S-C. & Hardie, G., 3 Mar 2020, In : Cell Metabolism. 31, 3, p. 472-492 21 p.

Research output: Contribution to journalReview article

3 Citations (Scopus)

An additional role for SUMO in ubiquitin-mediated proteolysis

Geoffroy, M-C. & Hay, R. T., Aug 2009, In : Nature Reviews Molecular Cell Biology. 10, 8, p. 564-568 5 p.

Research output: Contribution to journalReview article

179 Citations (Scopus)

Analysis of branched nucleic acid structure using comparative gel electrophoresis

Lilley, D. M. J., Feb 2008, In : Quarterly Reviews of Biophysics. 41, 1, p. 139 39 p.

Research output: Contribution to journalReview article

21 Citations (Scopus)

Analysis of plant diversity with retrotransposon-based molecular markers

Kalendar, R., Flavell, A. J., Ellis, T. H. N., Sjakste, T., Moisy, C. & Schulman, A. H., Apr 2011, In : Heredity. 106, 4, p. 520-530 11 p.

Research output: Contribution to journalReview article

156 Citations (Scopus)