Find Research Outputs

2019
48 Downloads (Pure)

A highly mutagenised barley (cv. Golden Promise) TILLING population coupled with strategies for screening-by-sequencing

Schreiber, M., Barakate, A., Uzrek, N., Macaulay, M., Sourdille, A., Morris, J., Hedley, P. E., Ramsay, L. & Waugh, R., 24 Aug 2019, In : Plant Methods. 15, p. 1-14 14 p., 99.

Research output: Contribution to journalArticle

Open Access
File
Hordeum
barley
screening
mutation
Mutation
58 Downloads (Pure)

A high-throughput screen for the identification of compounds that inhibit nematode gene expression by targeting spliced leader trans-splicing

Pandarakalam, G. C., Speake, M., McElroy, S., Alturkistani, A., Philippe, L., Pettitt, J., Müller, B. & Connolly, B., Aug 2019, In : International Journal for Parasitology: Drugs and Drug Resistance. 10, p. 28-37 10 p.

Research output: Contribution to journalArticle

Open Access
File
Spliced Leader RNA
Trans-Splicing
Gene Targeting
Anthelmintics
Gene Expression
3 Citations (Scopus)
79 Downloads (Pure)

A Human iPSC-derived 3D platform using primary brain cancer cells to study drug development and personalized medicine

Plummer, S., Wallace, S., Ball, G., Lloyd, R., Schiapparelli, P., Quiñones-Hinojosa, A., Hartung, T. & Pamies, D., 5 Feb 2019, In : Scientific Reports. 9, 1, p. 1-11 11 p., 1407.

Research output: Contribution to journalArticle

Open Access
File
temozolomide
Precision Medicine
Glioblastoma
Brain Neoplasms
Doxorubicin
4 Citations (Scopus)

Airway Bacterial Load and Inhaled Antibiotic Response in Bronchiectasis

Sibila, O., Laserna, E., Shoemark, A., Keir, H. R., Finch, S., Rodrigo-Troyano, A., Perea, L., Lonergan, M., Goeminne, P. C. & Chalmers, J. D., 1 Jul 2019, In : American Journal of Respiratory and Critical Care Medicine. 200, 1, p. 33-41 9 p.

Research output: Contribution to journalArticle

Bronchiectasis
Bacterial Load
Anti-Bacterial Agents
Aztreonam
Quality of Life
5 Citations (Scopus)
94 Downloads (Pure)

Albugo candida race diversity, ploidy and host-associated microbes revealed using DNA sequence capture on diseased plants in the field

Jouet, A., Saunders, D. G. O., McMullan, M., Ward, B., Furzer, O., Jupe, F., Cevik, V., Hein, I., Thilliez, G. J. A., Holub, E., Oosterhout, C. V. & Jones, J. D. G., 1 Feb 2019, In : New Phytologist. 221, 3, p. 1529-1543 15 p.

Research output: Contribution to journalArticle

Open Access
File
Albugo candida
Plant Diseases
Ploidies
ploidy
Candida
51 Downloads (Pure)

Alcohol screening and assessment measures for young people: A systematic review and meta-analysis of validation studies

Toner, P., Böhnke, J., Anderson, P. & McCambridge, J., 1 Sep 2019, In : Drug and Alcohol Dependence. 202, p. 39-49 11 p.

Research output: Contribution to journalReview article

Open Access
File
Validation Studies
Meta-Analysis
Screening
Alcohols
Literature
1 Citation (Scopus)
72 Downloads (Pure)

Alcohol use and breast cancer risk: A qualitative study of women’s perspectives to inform the development of a preventative intervention in breast clinics

Chambers, S. E. ., Copson, E. R., Dutey-Magni, P. F., Priest, C., Anderson, A. S. & Sinclair, J. M. A., Jul 2019, In : European Journal of Cancer Care. 28, 4, 8 p., e13075.

Research output: Contribution to journalArticle

Open Access
File
Breast
Alcohols
Breast Neoplasms
Focus Groups
Interviews

Allen, Building Early Modern Edinburgh: A Social History of Craftwork and Incorporation

MacDonald, A., Oct 2019, In : Scottish Historical Review. 98, 2, p. 309-311 3 p.

Research output: Contribution to journalBook/Film/Article review

2 Citations (Scopus)
84 Downloads (Pure)

Allopurinol treatment adversely impacts left ventricular mass regression in patients with well-controlled hypertension

Gingles, C., Symon, R., Gandy, S., Struthers, A., Houston, G., MacDonald, T., Lang, C., Donnan, P. & George, J., Dec 2019, In : Journal of Hypertension. 37, 12, p. 2481-2489 9 p.

Research output: Contribution to journalArticle

Open Access
File
Allopurinol
Hypertension
Placebos
Oxidative Stress
Left Ventricular Hypertrophy

Allosteric mechanism for site-specific ubiquitination of FANCD2

Chaugule, V. K., Arkinson, C., Rennie, M. L., Kämäräinen, O., Toth, R. & Walden, H., 23 Dec 2019, In : Nature Chemical Biology.

Research output: Contribution to journalArticle

Allosteric Site
Fanconi Anemia
Ubiquitination
DNA Repair
Catalytic Domain
1 Citation (Scopus)
73 Downloads (Pure)

A localized surface plasmon resonance-amplified immunofluorescence biosensor for ultrasensitive and rapid detection of nonstructural protein 1 of Zika virus

Takemura, K., Adegoke, O., Suzuki, T. & Park, E. Y., 31 Jan 2019, In : PLoS ONE. 14, 1, p. 1-14 14 p., e0211517.

Research output: Contribution to journalArticle

Open Access
File
Zika virus
surface plasmon resonance
Surface Plasmon Resonance
biosensors
Surface plasmon resonance
51 Downloads (Pure)

Altered mitochondrial bioenergetics are responsible for the delay in Wallerian degeneration observed in neonatal mice

Kline, R. A., Dissanayake, K. N., Hurtado, M. L., Martínez, N. W., Ahl, A., Mole, A. J., Lamont, D. J., Court, F. A., Ribchester, R. R., Wishart, T. M. & Murray, L. M., 1 Oct 2019, In : Neurobiology of Disease. 130, p. 1-16 16 p., 104496.

Research output: Contribution to journalArticle

Open Access
File
Wallerian Degeneration
Energy Metabolism
Axons
Oxidative Phosphorylation
Wounds and Injuries
4 Downloads (Pure)

Alternative Splicing of Circadian Clock Genes Correlates With Temperature in Field-Grown Sugarcane

Dantas, L. L. B., Calixto, C. P. G., Dourado, M. M., Carneiro, M. S., Brown, J. W. S. & Hotta, C. T., 23 Dec 2019, In : Frontiers in Plant Science. 10, p. 1-15 15 p., 1614.

Research output: Contribution to journalArticle

Open Access
File
alternative splicing
circadian rhythm
sugarcane
temperature
genes
50 Downloads (Pure)
Open Access
File
Biomedical Technology
Longitudinal Studies
Research
Blood Glucose
Inventions

Amber Room: Meyer Riegger, Karlsruhe

Myles, S., 2019

Research output: Non-textual formExhibition

Amber

A methodological framework for evaluating knowledge management of public sector: the case of the prefecture of eastern Macedonia and Thrace

Vasileiadis, I. & Fragouli, E., 14 Oct 2019, ICILLT October-2019 Conference Proceeding.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Knowledge management
Public sector
Employees
Customer needs
Responsibility
2 Citations (Scopus)
41 Downloads (Pure)
Open Access
File
Carbonates
Nanoparticles
Fungi
Minerals
Amino Acids
20 Downloads (Pure)

Amino acid substitutions in the human homomeric β3 GABAA receptor that enable activation by GABA

Gottschald Chiodi, C., Baptista-Hon, D., Hunter, W. & Hales, T., 15 Feb 2019, In : Journal of Biological Chemistry. 294, 7, p. 2375-2385 11 p.

Research output: Contribution to journalArticle

Open Access
File
GABA-A Receptors
Amino Acid Substitution
gamma-Aminobutyric Acid
Substitution reactions
Chemical activation
1 Citation (Scopus)

A missense mutation in the catalytic domain of O-GlcNAc transferase links perturbations in protein O-GlcNAcylation to X-linked intellectual disability

Pravata, V. M., Gundogdu, M., Bartual, S. G., Ferenbach, A. T., Stavridis, M., Õunap, K., Pajusalu, S., Žordania, R., Wojcik, M. H. & van Aalten, D. M. F., 7 Nov 2019, In : FEBS Letters.

Research output: Contribution to journalArticle

Missense Mutation
Intellectual Disability
Catalytic Domain
X ray crystallography
Stem cells

A mixed methods comparative evaluation of a low cost otoscope (Arclight) with a traditional device in twenty-one clinicians

Hey, S. Y., Buckley, J. C., Shahsavari, S., Kousha, O., Haddow, K. A., Blaikie, A. & Walker, F. D. L., 18 Jul 2019, In : Clinical Otolaryngology. 4 p.

Research output: Contribution to journalLetter

Otoscopes
Ear Diseases
Costs and Cost Analysis
Equipment and Supplies
Hearing Loss
1 Citation (Scopus)
Research
Barrett Esophagus
Pancreatitis
Patient Care
Delivery of Health Care

A modified Delphi process to establish future research priorities in malignant oesophagogastric surgery

Wilson, M. S. J., Blencowe, N. S., Boyle, C., Knight, S. R., Petty, R., Vohra, R. S. & Underwood, T. J., 16 Dec 2019, In : Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland. 6 p.

Research output: Contribution to journalArticle

Research
Neoplasms
Genomics
Patient Care
Delivery of Health Care
economics
physical science
persistence
analysis
policy

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

LifeLines Cohort Study, Sung, Y. J., de Las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., Manning, A. K., Brown, M. R., Aschard, H., Feitosa, M. F., Franceschini, N., Lu, Y., Cheng, C-Y., Sim, X., Vojinovic, D. & 40 others, Marten, J., Musani, S. K., Kilpeläinen, T. O., Richard, M. A., Aslibekyan, S., Bartz, T. M., Dorajoo, R., Li, C., Liu, Y., Rankinen, T., Smith, A. V., Tajuddin, S. M., Tayo, B. O., Zhao, W., Zhou, Y., Matoba, N., Sofer, T., Alver, M., Amini, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Giulianini, F., Goel, A., Harris, S. E., Hartwig, F. P., Connell, J. M., Smith, B. H., Rotter, J. I., Franks, P. W., Rice, K., Elliott, P., Caulfield, M. J., Gauderman, W. J., Munroe, P. B., Rao, D. C. & Morrison, A. C., 1 Aug 2019, In : Human Molecular Genetics. 28, 15, p. 2615-2633 19 p.

Research output: Contribution to journalArticle

Arterial Pressure
Smoking
Genome
Blood Pressure
Genes
4 Citations (Scopus)
20 Downloads (Pure)

A Multicenter, Randomized, Placebo-Controlled Trial of Atorvastatin for the Primary Prevention of Cardiovascular Events in Patients With Rheumatoid Arthritis: A multicenter, randomized, placebo controlled trial

Kitas, G. D., Nightingale, P., Armitage, J., Sattar, N., Belch, J. J. F. & Symmons, D. P. M., Sep 2019, In : Arthritis and Rheumatology. 71, 9, p. 1437-1449 13 p.

Research output: Contribution to journalArticle

Open Access
File
Primary Prevention
Rheumatoid Arthritis
Randomized Controlled Trials
Placebos
Risk Reduction Behavior
19 Downloads (Pure)

A multicentre parallel-group randomised trial assessing multiparametric MRI characterisation and image-guided biopsy of prostate in men suspected of having prostate cancer: MULTIPROS study protocol

Szewczyk-Bieda, M., Wei, C., Coll, K., Gandy, S., Donnan, P., Ragupathy, S. K. A., Singh, P., Wilson, J. & Nabi, G., 21 Nov 2019, In : Trials. 20, p. 1-8 8 p., 638.

Research output: Contribution to journalArticle

Open Access
File
Image-Guided Biopsy
Prostate
Prostatic Neoplasms
Biopsy
Magnetic Resonance Imaging
71 Downloads (Pure)

A multimodal approach to cardiovascular risk stratification in patients with type 2 diabetes incorporating retinal, genomic and clinical features

Fetit, A., Doney, A., Hogg, S., Wang, R., MacGillivray, T., Wardlaw, J. M., Doubal, F. N., McKay, G. J., McKenna, S. & Trucco, E., 5 Mar 2019, In : Scientific Reports. 9, 1, p. 1-10 10 p., 3591.

Research output: Contribution to journalArticle

Open Access
File
Type 2 Diabetes Mellitus
Single Nucleotide Polymorphism
Biomarkers
Blood Pressure
HDL Lipoproteins
9 Downloads (Pure)

Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer's Disease

Pickett, E. K., Herrmann, A. G., McQueen, J., Abt, K., Dando, O., Tulloch, J., Jain, P., Dunnett, S., Sohrabi, S., Fjeldstad, M. P., Calkin, W., Murison, L., Jackson, R. J., Tzioras, M., Stevenson, A., d'Orange, M., Hooley, M., Davies, C., Colom-Cadena, M., Anton-Fernandez, A. & 10 others, King, D., Oren, I., Rose, J., McKenzie, C. A., Allison, E., Smith, C., Hardt, O., Henstridge, C. M., Hardingham, G. E. & Spires-Jones, T. L., 10 Dec 2019, In : Cell Reports. 29, 11, p. 3592-3604.e5

Research output: Contribution to journalArticle

Open Access
File
Amyloid
Alzheimer Disease
Amyloid beta-Peptides
Phenotype
tau Proteins
81 Downloads (Pure)

Análisis de la formación y el ámbito de práctica de los médicos de atención primaria en Inglaterra, Alemania y España

Translated title of the contribution: Exploring the training and scope of practice of GPs in England, Germany and SpainGlonti, K., Struckmann, V., Alconada, A., Pettigrew, L. M., Hernandez-Santiago, V., Minue, S., Risso-Gill, I., McKee, M. & Legido-Quigley, H., Mar 2019, In : Gaceta Sanitaria. 33, 2, p. 148-155 8 p.

Research output: Contribution to journalArticle

Open Access
File
England
Spain
Germany
Primary Health Care
General Practitioners

An Alternative Genealogy for Global Capitalism: The Rhine Becomes an Inland Sea 1792-1815

Livesey, J., 1 Nov 2019, In : Critical Historical Studies. 6, 2, p. 223-245 23 p.

Research output: Contribution to journalArticle

Capitalism
Global Capitalism
Rhine
Genealogy
French Revolution
14 Downloads (Pure)

Analysing trajectories of a longitudinal exposure: a causal perspective on common methods in lifecourse research

Gadd, S. C., Tennant, P. W. G., Heppenstall, A. J., Boehnke, J. & Gilthorpe, M. S., 4 Dec 2019, In : PLoS ONE. 14, 12, p. 1-12 12 p., e0225217.

Research output: Contribution to journalArticle

Open Access
File
Glycosylated Hemoglobin A
research methods
trajectories
Trajectories
glycohemoglobin

Analysis of DrkA kinase's role in STATa activation

Saga, Y., Iwade, Y., Araki, T., Ishikawa, M. & Kawata, T., 17 Jun 2019, In : Genes to Cells. 24, 6, p. 422-435 14 p.

Research output: Contribution to journalArticle

Phosphotransferases
Tyrosine
Dictyostelium
Phosphorylation
Protein-Tyrosine Kinases

Analysis of sustainable net cage and fluid flows through the review

Zhu, M., Li, S., Liu, T., Sun, R. & Dai, J., 2019, Proceedings of the 13th International Conference on Management Science and Engineering Management, 2019. Xu, J., Ahmed, S. E., Cooke, F. L. & Duca, G. (eds.). Switzerland: Springer Verlag, Vol. 2. p. 270-278 9 p. (Advances in Intelligent Systems and Computing; vol. 1002).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Aquaculture
Flow of fluids
Fluids
Fish
Farms

Analytical Evaluation of Cellular Network Uplink Communications with Higher Order Sectorization Deployments

He, J., Guan, W., Guo, W., Liu, W. & Cheng, W., 10 Sep 2019, In : IEEE Transactions on Vehicular Technology. p. 1-11 11 p.

Research output: Contribution to journalArticle

Telecommunication networks
Analytical models
Random variables
Long Term Evolution (LTE)
Directional patterns (antenna)
environmental law
European Union
governance
legislation
environmental legislation
3 Downloads (Pure)

An annotated corpus of argument schemes in US election debates

Visser, J., Lawrence, J., Wagemans, J. & Reed, C., 2019, Proceedings of the 9th Conference of the International Society for the Study of Argumentation (ISSA), 3-6 July 2018 . p. 1101-1111 11 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access
File
election
presidential election
argumentation
social media
television
1 Citation (Scopus)
Genetic Counseling
High-Throughput Nucleotide Sequencing
Neoplasms
Hope
Exome
93 Downloads (Pure)
Open Access
File
Methylenetetrahydrofolate Dehydrogenase (NADP)
dehydrogenases
inhibitors
Ligands
enzymes
40 Downloads (Pure)
Open Access
File
Orthodontics
Meta-Analysis
Randomized Controlled Trials
Tooth
Databases
1 Citation (Scopus)

An efficient wideband spectrum sensing algorithm for unmanned aerial vehicle communication networks

Xu, W., Wang, S., Yan, S. & He, J., Apr 2019, In : IEEE Internet of Things Journal. 6, 2, p. 1768-1780 13 p., 8542704.

Research output: Contribution to journalArticle

Unmanned aerial vehicles (UAV)
Telecommunication networks
Cognitive radio
Computational complexity
Notch filters

An energy stable C0 finite element scheme for a quasi-incompressible phase-field model of moving contact line with variable density

Shen, L., Huang, H., Lin, P., Song, Z. & Xu, S., 10 Dec 2019, In : Journal of Computational Physics. 405, p. 1-27 27 p., 109179.

Research output: Contribution to journalArticle

Contact Line
Phase Field Model
Two phase flow
electric contacts
Boundary conditions
27 Downloads (Pure)

A new approach for determination of free carriers lifetime and density of localised states in disordered semiconductors

Belgacem, H. & Reynolds, S., 17 Jan 2019, In : Philosophical Magazine. 99, 2, p. 131-147 17 p.

Research output: Contribution to journalArticle

Open Access
File
Carrier lifetime
Photoconductivity
Carrier concentration
Semiconductor materials
Laplace transforms
1 Citation (Scopus)
66 Downloads (Pure)

A New Front in Microbial Warfare—Delivery of Antifungal Effectors by the Type VI Secretion System

Trunk, K., Coulthurst, S. & Quinn, J., Jun 2019, In : Journal of Fungi. 5, 2, p. 1-13 13 p., 50.

Research output: Contribution to journalReview article

Open Access
File
Weapons
Fungi
Microbiota
Autophagy
Gram-Negative Bacteria

An Expanded Mixed Finite Element Method for Two-dimensional Sobolev Equations

Li, N., Lin, P. & Gao, F., 1 Mar 2019, In : Journal of Computational and Applied Mathematics. 348, p. 342-355 14 p.

Research output: Contribution to journalArticle

Mixed Finite Element Method
Finite element method
Optimal Error Estimates
Verify
Numerical Examples

An Exploration of Experiences of Transdisciplinary Research in Aging and Technology

Wada, M., Grigorovich, A., Fang, M. L., Sixsmith, J. & Kontos, P., 28 Oct 2019, (Accepted/In press) In : Forum: Qualitative Social Research.

Research output: Contribution to journalArticle

transdisciplinary
experience
stakeholder
knowledge gap
communication research
1 Citation (Scopus)
48 Downloads (Pure)

An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials

Henderson, C. J., Kapelyukh, Y., Scheer, N., Rode, A., McLaren, A., MacLeod, K., Lin, D., Wright, J., Stanley, L. A. & Wolf, C. R., Jun 2019, In : Drug Metabolism and Disposition. 47, 6, p. 601-615 15 p.

Research output: Contribution to journalArticle

Open Access
File
Drug Interactions
Clinical Trials
Pharmaceutical Preparations
Pharmacokinetics
Cytochrome P-450 CYP3A

An Image Processing System for Char Combustion Reactivity Characterisation

Chaves, D., Trucco, E., Barraza, J. & Trujillo, M. P., Apr 2019, In : Computers in Industry. 106, p. 60-70 11 p.

Research output: Contribution to journalArticle

Image processing
Coal
Petrology
Coal combustion
Fuel burners
3 Citations (Scopus)
51 Downloads (Pure)

Animal models of chemotherapy-induced peripheral neuropathy: a machine-assisted systematic review and meta-analysis

Currie, G. L., Angel-Scott, H. N., Colvin, L., Cramond, F., Hair, K., Khandoker, L., Liao, J., MacLeod, M. R., McCann, S. K., Morland, R., Sherratt, N., Stewart, R., Tanriver-Ayde, E., Thomas, J., Wang, Q., Wodarski, R., Xiong, R., Rice, A. S. C. & Sena, E. S., 20 May 2019, In : PLoS Biology. 17, 5, p. 1-34 34 p., e3000243.

Research output: Contribution to journalArticle

Open Access
File
Chemotherapy
peripheral nervous system diseases
systematic review
Peripheral Nervous System Diseases
meta-analysis
1 Citation (Scopus)
42 Downloads (Pure)

An influenza virus-triggered SUMO switch orchestrates co-opted endogenous retroviruses to stimulate host antiviral immunity

Schmidt, N., Domingues, P., Golebiowski, F., Patzina, C., Tatham, M. H., Hay, R. T. & Hale, B. G., 27 Aug 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 35, p. 17399-17408 10 p.

Research output: Contribution to journalArticle

Open Access
File
Endogenous Retroviruses
Ubiquitin
Orthomyxoviridae
Antiviral Agents
Immunity

An investigation into the lexical boost with nonhead nouns

Carminati, M. N., van Gompel, R. P. G. & Wakeford, L. J., Oct 2019, In : Journal of Memory and Language. 108, p. 1-19 19 p., 104031.

Research output: Contribution to journalArticle

Head
experiment
Experiments
Licensure
Syntactics