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2019
39 Downloads (Pure)

Ability of verbal autopsy data to detect deaths due to uncontrolled hyperglycaemia: testing existing methods and development and validation of a novel weighted score

Blackstock, S., Witham, M. D., Wade, A. N., Crampin, A., Beran, D., Ogle, G. D. & Davies, J. I., 18 Oct 2019, In : BMJ Open. 9, 10, p. 1-8 8 p., e026331.

Research output: Contribution to journalArticle

Open Access
File
Hyperglycemia
Autopsy
Physicians
Malawi
South Africa
73 Downloads (Pure)

Effect of vitamin K2 on postural sway in older people who fall: A Randomized Controlled Trial

Witham, M. D., Price, R. J. G., Band, M. M., Hannah, M. S., Fulton, R. L., Clarke, C. L., Donnan, P. T., McNamee, P., Cvoro, V. & Soiza, R. L., 18 Jun 2019, In : Journal of the American Geriatrics Society. 6 p.

Research output: Contribution to journalArticle

Open Access
File
Vitamin K 2
Randomized Controlled Trials
Placebos
Confidence Intervals
Health Care Costs

External Validation of a Risk Score to Predict Aki in Either the Community or Hospital Setting

Bell, S., James, M., Farmer, C., Tan, Z., De Souza, N. & Witham, M., 13 Jun 2019, In : Nephrology Dialysis Transplantation. 34

Research output: Contribution to journalMeeting abstract

69 Downloads (Pure)

Impact of introducing electronic acute kidney injury alerts in primary care

Aiyegbusi, O., Witham, M., Lim, M., Gauld, G. & Bell, S., Apr 2019, In : Clinical Kidney Journal. 12, 2, p. 253-257 5 p.

Research output: Contribution to journalArticle

Open Access
File
Acute Kidney Injury
Primary Health Care
Creatinine
Biochemistry
Hospitalization
1 Citation (Scopus)
83 Downloads (Pure)

Podiatry interventions to prevent falls in older people: a systematic review and meta-analysis

Wylie, G., Torrens, C., Campbell, P., Frost, H., Gordon, A. L., Menz, H. B., Skelton, D. A., Sullivan, F., Witham, M. D. & Morris, J., May 2019, In : Age and Ageing. 48, 3, p. 327-336 10 p.

Research output: Contribution to journalArticle

Open Access
File
Podiatry
Meta-Analysis
Home Care Services
Foot
Referral and Consultation
111 Downloads (Pure)

Serum sodium level variability as a prognosticator in older adults

Barma, M. A., Soiza, R. L., Donnan, P. T., McGilchrist, M. M., Frost, H. & Witham, M. D., 3 Jan 2019, In : Scandinavian Journal of Clinical and Laboratory Investigation. 78, 7-8, p. 632-638 7 p.

Research output: Contribution to journalArticle

Open Access
File
Sodium
Serum
Patient rehabilitation
Hypernatremia
Biochemistry
2018
1 Citation (Scopus)
43 Downloads (Pure)
Open Access
File
Cholinergic Antagonists
Scotland
Hypnotics and Sedatives
Opioid Analgesics
Cohort Studies
41 Downloads (Pure)

Calcium Channel Blockers Are Associated With Improved Survival and Lower Cardiovascular Mortality in Patients With Renovascular Disease

Desmukh, H., Barker, E., Ambarasan, T., Levin, D., Bell, S., Witham, M. D. & George, J., 29 Oct 2018, In : Cardiovascular Therapeutics. 36, 6, p. 1-7 7 p., e12474.

Research output: Contribution to journalArticle

Open Access
File
Calcium Channel Blockers
Renal Artery Obstruction
Blood Pressure
Survival
Mortality
1 Citation (Scopus)

Cardiovascular Disease Profile of the Oldest Adults in Rural South Africa: Data from the HAALSI Study (Health and Aging in Africa: Longitudinal Studies of INDEPTH Communities)

Jardim, T. V., Witham, M. D., Abrahams-Gessel, S., Gómez-Olivé, F. X., Tollman, S., Berkman, L. & Gaziano, T. A., 14 Nov 2018, In : Journal of the American Geriatrics Society. 66, 11, p. 2151-2157 7 p.

Research output: Contribution to journalArticle

South Africa
Longitudinal Studies
Cardiovascular Diseases
Odds Ratio
Confidence Intervals
112 Downloads (Pure)
Open Access
File
Patient rehabilitation
Medicine
Rehabilitation
Pulmonary diseases
Inpatients
3 Citations (Scopus)
121 Downloads (Pure)

Cross-sectional relationship between Haemoglobin concentration and measures of physical and cognitive function in an older rural South African population

Payne, C. F., Davies, J. I., Gomez-Olive, F. X., Hands, K. J., Kahn, K., Kobayashi, L. C., Tipping, B., Tollman, S., Wade, A. & Witham, M., 9 Aug 2018, In : Journal of Epidemiology and Community Health. 72, 9, p. 796-802 7 p.

Research output: Contribution to journalArticle

Open Access
File
Cognition
Hemoglobins
Population
Hand Strength
Anemia
20 Citations (Scopus)
102 Downloads (Pure)

Effect of vitamin D supplementation on markers of vascular function: a systematic review and individual participant meta-analysis

Beveridge, L., Khan, F., Struthers, A., Armitage, J., Barchetta, I., Cavallo, M. G., Clarke, R., Dalan, R., Dreyer, G., Gepner, A. D., Forouhi, N. G., Harris, R. A. ., Hitman, G. A., Larsen, T., Khadgawat, R., Marckmann, P., Mose, F. H. ., Pilz, S., Scholze, A., Shargorodsky, M. & 4 others, Sokol, S. I., Stricker, H., Zoccali, C. & Witham, M., 30 May 2018, In : Journal of the American Heart Association. 7, 11, p. 1-21 21 p., e008273.

Research output: Contribution to journalArticle

Open Access
File
Vitamin D
Blood Vessels
Meta-Analysis
Pulse Wave Analysis
Brachial Artery
4 Citations (Scopus)
143 Downloads (Pure)

Establishing a clinical phenotype for cachexia in end stage kidney disease: study protocol

Reid, J., Noble, H. R., Adamson, G., Davenport, A., Farrington, K., Fouque, D., Kalantar-Zadeh, K., Mallett, J., McKeaveney, C., Porter, S., Seres, D. S., Shields, J., Slee, A., Witham, M. D. & Maxwell, A. P., 13 Feb 2018, In : BMC Nephrology. 19, 1, p. 38 6 p., 38.

Research output: Contribution to journalArticle

Open Access
File
Cachexia
Chronic Kidney Failure
Phenotype
Muscles
Anorexia
7 Citations (Scopus)
58 Downloads (Pure)

Hypertension treatment for older people-navigating between Scylla and Charybdis

Conroy, S. P., Westendorp, R. G. J. & Witham, M. D., Jul 2018, In : Age and Ageing. 47, 4, p. 505-508 4 p.

Research output: Contribution to journalArticle

Open Access
File
Hypertension
Dementia
Decision Making
Blood Pressure
Therapeutics
25 Citations (Scopus)
49 Downloads (Pure)

Impact of exercise-based cardiac rehabilitation in patients with heart failure (ExTraMATCH II) on mortality and hospitalisation: an individual-patient data meta-analysis of randomised trials

Taylor, R. S. ., Walker, S., Smart, N. A., Piepoli, M. F., Warren, F. C., Ciani, O., O'Connor, C. M., Whellan, D., Keteyian, S. J., Coats, A. J. S., Davos, C. H., Dalal, H. M., Dracup, K., Evangelista, L., Jolly, K., Myers, J., McKelvie, R. S., Nilsson, B. B., Passino, C., Witham, M. & 2 others, Yeh, G. Y. & Olsen Zwisler, A-D., 1 Dec 2018, In : European Journal of Heart Failure. 20, 12, p. 1735-1743 9 p.

Research output: Contribution to journalArticle

Open Access
File
Meta-Analysis
Hospitalization
Heart Failure
Exercise
Mortality
10 Citations (Scopus)
132 Downloads (Pure)

Leucine and ACE inhibitors as therapies for sarcopenia (LACE trial): study protocol for a randomised controlled trial

Band, M. M., Sumukadas, D., Struthers, A. D., Avenell, A., Donnan, P. T., Kemp, P. R., Smith, K. T., Hume, C. L., Hapca, A. & Witham, M. D., 1 Jan 2018, In : Trials. 19, p. 1-11 11 p., 6.

Research output: Contribution to journalArticle

Open Access
File
Sarcopenia
Clinical Protocols
Angiotensin-Converting Enzyme Inhibitors
Leucine
Randomized Controlled Trials
1 Citation (Scopus)
126 Downloads (Pure)

Systematic Techniques to Enhance rEtention in Randomised controlled trials: the STEER study protocol

Gillies, K., Bower, P., Elliott, J., MacLennan, G., Newlands, R. S. N., Ogden, M., Treweek, S. P., Wells, M., Witham, M. D., Young, B. & Francis, J. J., 27 Mar 2018, In : Trials. 19, 1, p. 1-10 10 p., 197.

Research output: Contribution to journalArticle

Open Access
File
Randomized Controlled Trials
Research
Focus Groups
Lenses
Clinical Trials
1 Citation (Scopus)
149 Downloads (Pure)

The effect of perindopril on postural instability in older people with a history of falls-a randomised controlled trial

Sumukadas, D., Price, R., McMurdo, M. E. T., Rauchhaus, P., Struthers, A., McSwiggan, S., Arnold, G., Abboud, R. & Witham, M., 1 Jan 2018, In : Age and Ageing. 47, 1, p. 75-81 7 p.

Research output: Contribution to journalArticle

Open Access
File
Perindopril
Randomized Controlled Trials
Placebos
Muscle Strength
Orthostatic Hypotension
2017
2 Citations (Scopus)
129 Downloads (Pure)

Association between bisphosphonate therapy and outcomes from rehabilitation in older people

Goodbrand, J. A., Hughes, L. D., Cochrane, L., Donnan, P., McGilchrist, M., Frost, H., McMurdo, M. & Witham, M., May 2017, In : Archives of Gerontology and Geriatrics. 70, p. 195-200 6 p.

Research output: Contribution to journalArticle

Open Access
File
Diphosphonates
rehabilitation
death
Rehabilitation
hospitalization
123 Downloads (Pure)

Bringing all together for research capacity building in LMICs - Authors' reply

Beran, D., Byass, P., Gbakima, A., Kahn, K., Sankoh, O., Tollman, S., Witham, M. & Davies, J., Sep 2017, In : The Lancet Global Health. 5, 9, p. e870 1 p.

Research output: Contribution to journalLetter

Open Access
File
88 Citations (Scopus)

Cardiovascular and metabolic effects of metformin in patients with type 1 diabetes (REMOVAL): a double-blind, randomised, placebo-controlled trial

Petrie, J. R., Chaturvedi, N., Ford, I., Brouwers, M. C. G. J., Greenlaw, N., Tillin, T., Hramiak, I., Hughes, A. D., Jenkins, A. J., Klein, B. E. K., Klein, R., Ooi, T. C., Rossing, P., Stehouwer, C. D. A., Sattar, N. & Colhoun, H. M., 1 Aug 2017, In : The Lancet Diabetes and Endocrinology. 5, 8, p. 597-609 13 p.

Research output: Contribution to journalArticle

Metformin
Type 1 Diabetes Mellitus
Randomized Controlled Trials
Placebos
Carotid Intima-Media Thickness
3 Citations (Scopus)
83 Downloads (Pure)

Conducting and reporting trials for older people

Witham, M. D. & Stott, D. J., 1 Nov 2017, In : Age and Ageing. 46, 6, p. 889-894 6 p.

Research output: Contribution to journalArticle

Open Access
File
Randomized Controlled Trials
Geriatrics
Manuscripts
Cognition
Uncertainty
6 Citations (Scopus)
136 Downloads (Pure)

Factors associated with change in objectively measured physical activity in older people: data from the Physical Activity Cohort Scotland study

Clarke, C., Sniehotta, F. F., Vadiveloo, T., Argo, I., Donnan, P., McMurdo, M. & Witham, M., 14 Aug 2017, In : BMC Geriatrics. 17, p. 1-9 9 p., 180.

Research output: Contribution to journalArticle

Open Access
File
Scotland
Cohort Studies
Exercise
Independent Living
Linear Models
5 Citations (Scopus)
133 Downloads (Pure)

Hospital-acquired pneumonia surveillance-an unmet need

Ewan, V. C., Witham, M. D., Kiernan, M. A. & Simpson, A. J., Oct 2017, In : The Lancet Respiratory Medicine. 5, 10, p. 771-772 2 p.

Research output: Contribution to journalComment/debate

Open Access
File

Interventions to Enhance Medication Adherence in Older Heart Failure Patients - A Systematic Review

Fulton, R., Kroll, T., McMurdo, M., Molloy, G. J. & Witham, M., 16 May 2017, In : Age and Ageing. 46, Supplement 1, p. i25 1 p.

Research output: Contribution to journalArticle

Medication Adherence
Heart Failure
Telephone
Patient Education
Drug Delivery Systems

Interventions to improve medication adherence in heart failure: A systematic review

Fulton, R. L., Kroll, T., McMurdo, M., Molloy, G. J. & Witham, M. D., 2017, In : Journal of Preventive Cardiology. 6, 3, p. 1048-1056 9 p.

Research output: Contribution to journalReview article

Medication Adherence
Heart Failure
Treatment Failure
MEDLINE
Sample Size
13 Citations (Scopus)
58 Downloads (Pure)

Metformin in adults with type 1 diabetes: Design and methods of REducing with MetfOrmin Vascular Adverse Lesions (REMOVAL): An international multicentre trial

Petrie, J. R., Chaturvedi, N., Ford, I., Hramiak, I., Hughes, A. D., Jenkins, A. J., E. Klein, B., Klein, R., Ooi, T. C., Rossing, P., Sattar, N. & Stehouwer, C. D. A., 1 Apr 2017, In : Diabetes, Obesity and Metabolism. 19, 4, p. 509-516 8 p.

Research output: Contribution to journalArticle

Open Access
File
Metformin
Type 1 Diabetes Mellitus
Multicenter Studies
Blood Vessels
Insulin

Podiatry interventions to reduce falls in older people

Morris, J., Witham, M., Campbell, P., Frost, H., Torrens, C. & Wylie, G., 2017, In : PROSPERO.

Research output: Contribution to journalReview article

Podiatry
Home Care Services
Placebos
4 Citations (Scopus)
130 Downloads (Pure)

Prevalence and correlates of frailty in an older rural African population: findings from the HAALSI cohort study

Payne, C. F., Wade, A., Kabudula, C. W., Davies, J. I., Change, A. Y., Gomez-Olive, F. X., Kahn, K., Berkman, L. F., Tollman, S., Salomon, J. A. & Witham, M., 28 Dec 2017, In : BMC Geriatrics. 17, p. 1-10 10 p., 293.

Research output: Contribution to journalArticle

Open Access
File
Rural Population
Cohort Studies
Health
Diagnostic Self Evaluation
Africa South of the Sahara
24 Citations (Scopus)
110 Downloads (Pure)

Research capacity building-obligations for global health partners

Beran, D., Byass, P., Gbakima, A., Kahn, K., Sankoh, O., Tollman, S., Witham, M. & Davies, J., Jun 2017, In : The Lancet Global Health. 5, 6, p. e567-e568 2 p.

Research output: Contribution to journalComment/debate

Open Access
File
6 Citations (Scopus)
124 Downloads (Pure)

Selecting Potential Pharmacological Interventions in Sarcopenia

Kilsby, A. J., Sayer, A. A. & Witham, M. D., Apr 2017, In : Drugs & Aging. 34, 4, p. 223-240 8 p.

Research output: Contribution to journalComment/debate

Open Access
File
Sarcopenia
Pharmacology
Myostatin
Muscles
Denervation
8 Citations (Scopus)
87 Downloads (Pure)

The emergence of sarcopenia as an important entity in older people

Offord, N. J. & Witham, M. D., 1 Aug 2017, In : Clinical Medicine - Journal of the Royal College of Physicians of London. 17, 4, p. 363-366 4 p.

Research output: Contribution to journalArticle

Open Access
File
Sarcopenia
Myostatin
Muscles
Allopurinol
Resistance Training
4 Citations (Scopus)
103 Downloads (Pure)

Turning predator into prey: the problem of predatory journal

Witham, M. D. & Runcie, H., Mar 2017, In : Journal of the Royal College of Physicians of Edinburgh. 47, 1, p. 3-4 2 p.

Research output: Contribution to journalEditorial

Open Access
File
9 Citations (Scopus)
322 Downloads (Pure)

Validation of the AX3 triaxial accelerometer in older functionally impaired people

Clarke, C. C., Taylor, J., Crighton, L. J., Goodbrand, J. A., McMurdo, M. E. T. & Witham, M. D., Jun 2017, In : Aging Clinical and Experimental Research. 29, 3, p. 451-457 7 p.

Research output: Contribution to journalArticle

Open Access
File
Exercise
Walking
Lower Extremity
Chronic Disease
Premature Mortality
5 Citations (Scopus)
84 Downloads (Pure)

Variations in disability and quality of life with age and sex between eight Lower and Middle Income Countries: data from the INDEPTH WHO-SAGE collaboration

Gomez-Olive, F. X., Schröders, J., Aboderin, I., Byass, P., Chatterji, S., Kahn, K., Kowal, P., Nathan, R., Ng, N., Razzaque, A., Sankoh, O., Streatfield, P. K., Tollman, S., Wilopo, S. A. & Witham, M. D., 20 Dec 2017, In : BMJ Global Health . 2, 4, 12 p., e000508.

Research output: Contribution to journalArticle

Open Access
File
Quality of Life
Regression Analysis
Demography
Ghana
Bangladesh
2016
3 Citations (Scopus)
67 Downloads (Pure)

A good death for the oldest old

Witham, M. D. & Hockley, J., 27 Apr 2016, In : Age and Ageing. 45, 3, p. 329-331 3 p.

Research output: Contribution to journalEditorial

Open Access
File
10 Citations (Scopus)
108 Downloads (Pure)

Allopurinol and oxypurinol promote osteoblast differentiation and increase bone formation

Orriss, I. R., Arnett, T. R., George, J. & Witham, M. D., 15 Mar 2016, In : Experimental Cell Research. 342, 2, p. 166-174 9 p.

Research output: Contribution to journalArticle

Open Access
File
Oxypurinol
Allopurinol
Osteoblasts
Osteogenesis
Xanthine Oxidase
176 Downloads (Pure)

An evaluation of the psychometric properties of the Indicator of Relative Need (IoRN) instrument

Canny, A., Robertson, F., Knight, P., Redpath, A. & Witham, M. D., 28 Jul 2016, In : BMC Geriatrics. 16, 10 p., 147.

Research output: Contribution to journalArticle

Open Access
File
Aptitude
Home Care Services
Activities of Daily Living
Psychometrics
Hospitalization
8 Citations (Scopus)
93 Downloads (Pure)

Association between allopurinol use and hip fracture in older patients

Basu, U., Goodbrand, J., McMurdo, M. E. T., Donnan, P. T., McGilchrist, M., Frost, H., George, J. & Witham, M. D., Mar 2016, In : Bone. 84, p. 189-193 5 p.

Research output: Contribution to journalArticle

Open Access
File
Allopurinol
Hip Fractures
Social Work
Hospitalization
Oxidative Stress
7 Citations (Scopus)
126 Downloads (Pure)

Association between GDF-15 levels and changes in vascular and physical function in older patients with hypertension

Barma, M., Khan, F., Price, R. J. G., Donnan, P. T., Messow, C. M., Ford, I., McConnachie, A., Struthers, A. D., McMurdo, M. E. T. & Witham, M. D., 2016, In : Aging Clinical and Experimental Research. 29, 5, p. 1055-1059 5 p.

Research output: Contribution to journalArticle

Open Access
File
Growth Differentiation Factor 15
Blood Vessels
Hypertension
Population
Walking
14 Citations (Scopus)

Effect of vitamin K on vascular health and physical function in older people with vascular disease–a randomised controlled trial

Fulton, R. L., McMurdo, M. E. T., Hill, A., Abboud, R. J., Arnold, G. P., Struthers, A. D., Khan, F., Vermeer, C., Knapen, M. H. J., Drummen, N. E. A. & Witham, M. D., Mar 2016, In : Journal of Nutrition Health & Aging. 20, 3, p. 325-333 9 p.

Research output: Contribution to journalArticle

Vitamin K
Blood Vessels
Randomized Controlled Trials
Vascular Diseases
Placebos
15 Citations (Scopus)
183 Downloads (Pure)

Hospital-acquired pneumonia incidence and diagnosis in older patients

Burton, L. A., Price, R., Barr, K. E., McAuley, S. M., Allen, J. B., Clinton, A. M., Phillips, G., Marwick, C. A., McMurdo, M. E. T. & Witham, M. D., Jan 2016, In : Age and Ageing. 45, 1, p. 171-174 4 p.

Research output: Contribution to journalArticle

Open Access
File
Pneumonia
Incidence
Length of Stay
Respiratory Signs and Symptoms
Patient Admission
1 Citation (Scopus)
142 Downloads (Pure)

Introduction to the Age and Ageing Sarcopenia collection

Witham, M. & Sayer, A. A., 2 Nov 2016, In : Age and Ageing. 45, 6, p. 752-753 2 p.

Research output: Contribution to journalArticle

Open Access
File
Sarcopenia
Skeletal Muscle
Clinical Trials
5 Citations (Scopus)
105 Downloads (Pure)

Should chronic metabolic acidosis be treated in older people with chronic kidney disease?

Witham, M. D. & Lamb, E. J., Nov 2016, In : Nephrology Dialysis Transplantation. 31, 11, p. 1796-1802 7 p.

Research output: Contribution to journalArticle

Open Access
File
Acidosis
Chronic Renal Insufficiency
Bicarbonates
Kidney
Health
1 Citation (Scopus)
162 Downloads (Pure)

Slower Decline in C-Reactive Protein after an Inflammatory Insult Is Associated with Longer Survival in Older Hospitalised Patients

Barma, M., Goodbrand, J. A., Donnan, P. T., McGilchrist, M. M., Frost, H., McMurdo, M. E. T. & Witham, M. D., 28 Jul 2016, In : PLoS ONE. 11, 7, 10 p., e0159412.

Research output: Contribution to journalArticle

Open Access
File
C-reactive protein
C-Reactive Protein
Survival
Recovery
rehabilitation (people)
2 Citations (Scopus)
167 Downloads (Pure)

Spironolactone for people aged 70 or over with osteoarthritic knee pain: a proof-of-concept trial

McMurdo, M. E. T., Sumukadas, D., Donnan, P. T., Cvoro, V., Rauchhaus, P., Argo, I., Waldie, H., Littleford, R., Struthers, A. D. & Witham, M. D., May 2016, In : Arthritis Care & Research. 68, 5, p. 716-721 6 p.

Research output: Contribution to journalArticle

Open Access
File
Spironolactone
Knee
Pain
Confidence Intervals
Knee Osteoarthritis
1 Citation (Scopus)
142 Downloads (Pure)
Open Access
File
Inpatients
Primary Health Care
Hemoglobins
Cohort Studies
Rehabilitation
2015
15 Downloads (Pure)

Ageing as a cross-cutting theme

Witham, M. D., 2015.

Research output: Contribution to conferenceOther

File
9 Citations (Scopus)
138 Downloads (Pure)

Association between kidney function, rehabilitation outcome, and survival in older patients discharged from inpatient rehabilitation

Doyle, E. M., Sloan, J. M., Goodbrand, J. A., McMurdo, M. E. T., Donnan, P. T., McGilchrist, M. M., Frost, H. & Witham, M. D., Nov 2015, In : American Journal of Kidney Diseases. 66, 5, p. 768-774 7 p.

Research output: Contribution to journalArticle

Open Access
File
Glomerular Filtration Rate
Inpatients
Rehabilitation
Kidney
Survival
8 Citations (Scopus)
Databases
Delivery of Health Care
Information Storage and Retrieval
Documentation
Informatics