Find Research Outputs

Search in all content

Filters for Research Outputs

Search concepts
Selected filters

Publication Year

  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011

Author

  • Roland Wolf
2019

An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials

Henderson, C. J., Kapelyukh, Y., Scheer, N., Rode, A., McLaren, A., MacLeod, K., Lin, D., Wright, J., Stanley, L. A. & Wolf, C. R., Jun 2019, In : Drug Metabolism and Disposition. 47, 6, p. 601-615 15 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
78 Downloads (Pure)

Application of hepatic cytochrome b5/P450 reductase null (HBRN) mice to study the role of cytochrome b5 in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine

Reed, L., Indra, R., Mrizova, I., Moserova, M., Schmeiser, H. H., Wolf, C. R., Henderson, C. J., Stiborova, M., Phillips, D. H. & Arlt, V. M., 1 Mar 2019, In : Toxicology and Applied Pharmacology. 366, p. 64-74 11 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
120 Downloads (Pure)

Constitutive androstane receptor 1 is constitutively bound to chromatin and ‘primed’ for transactivation in hepatocytes

McMahon, M., Ding, S., Acosta-Jimenez, L., Terranova, R., Gerard, M-A., Vitobello, A., Moggs, J. G., Henderson, C. J. & Wolf, C. R., 1 Jan 2019, In : Molecular Pharmacology. 95, 1, p. 97-105 9 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
122 Downloads (Pure)
Open Access
File
2 Citations (Scopus)
6 Downloads (Pure)

Discovery of common and rare genetic risk variants for colorectal cancer

Huyghe, J. R., Bien, S. A., Harrison, T. A., Kang, H. M., Chen, S., Schmit, S. L., Conti, D. V., Qu, C., Jeon, J., Edlund, C. K., Greenside, P., Wainberg, M., Schumacher, F. R., Smith, J. D., Levine, D. M., Nelson, S. C., Sinnott-Armstrong, N. A., Albanes, D., Alonso, M. H., Anderson, K. & 179 others, Arnau-Collell, C., Arndt, V., Bamia, C., Banbury, B. L., Baron, J. A., Berndt, S. I., Bézieau, S., Bishop, D. T., Boehm, J., Boeing, H., Brenner, H., Brezina, S., Buch, S., Buchanan, D. D., Burnett-Hartman, A., Butterbach, K., Caan, B. J., Campbell, P. T., Carlson, C. S., Castellví-Bel, S., Chan, A. T., Chang-Claude, J., Chanock, S. J., Chirlaque, M-D., Cho, S. H., Connolly, C. M., Cross, A. J., Cuk, K., Curtis, K. R., de la Chapelle, A., Doheny, K. F., Duggan, D., Easton, D. F., Elias, S. G., Elliott, F., English, D. R., Feskens, E. J. M., Figueiredo, J. C., Fischer, R., FitzGerald, L. M., Forman, D., Gala, M., Gallinger, S., Gauderman, W. J., Giles, G. G., Gillanders, E., Gong, J., Goodman, P. J., Grady, W. M., Grove, J. S., Gsur, A., Gunter, M. J., Haile, R. W., Hampe, J., Hampel, H., Harlid, S., Hayes, R. B., Hofer, P., Hoffmeister, M., Hopper, J. L., Hsu, W-L., Huang, W-Y., Hudson, T. J., Hunter, D. J., Ibañez-Sanz, G., Idos, G. E., Ingersoll, R., Jackson, R. D., Jacobs, E. J., Jenkins, M. A., Joshi, A. D., Joshu, C. E., Keku, T. O., Key, T. J., Kim, H. R., Kobayashi, E., Kolonel, L. N., Kooperberg, C., Kühn, T., Küry, S., Kweon, S-S., Larsson, S. C., Laurie, C. A., Le Marchand, L., Leal, S. M., Lee, S. C., Lejbkowicz, F., Lemire, M., Li, C. I., Li, L., Lieb, W., Lin, Y., Lindblom, A., Lindor, N. M., Ling, H., Louie, T. L., Männistö, S., Markowitz, S. D., Martín, V., Masala, G., McNeil, C. E., Melas, M., Milne, R. L., Moreno, L., Murphy, N., Myte, R., Naccarati, A., Newcomb, P. A., Offit, K., Ogino, S., Onland-Moret, N. C., Pardini, B., Parfrey, P. S., Pearlman, R., Perduca, V., Pharoah, P. D. P., Pinchev, M., Platz, E. A., Prentice, R. L., Pugh, E., Raskin, L., Rennert, G., Rennert, H. S., Riboli, E., Rodríguez-Barranco, M., Romm, J., Sakoda, L. C., Schafmayer, C., Schoen, R. E., Seminara, D., Shah, M., Shelford, T., Shin, M-H., Shulman, K., Sieri, S., Slattery, M. L., Southey, M. C., Stadler, Z. K., Stegmaier, C., Su, Y-R., Tangen, C. M., Thibodeau, S. N., Thomas, D. C., Thomas, S. S., Toland, A. E., Trichopoulou, A., Ulrich, C. M., Van Den Berg, D. J., van Duijnhoven, F. J. B., Van Guelpen, B., van Kranen, H., Vijai, J., Visvanathan, K., Vodicka, P., Vodickova, L., Vymetalkova, V., Weigl, K., Weinstein, S. J., White, E., Win, A. K., Wolf, C. R., Wolk, A., Woods, M. O., Wu, A. H., Zaidi, S. H., Zanke, B. W., Zhang, Q., Zheng, W., Scacheri, P. C., Potter, J. D., Bassik, M. C., Kundaje, A., Casey, G., Moreno, V., Abecasis, G. R., Nickerson, D. A., Gruber, S. B., Hsu, L. & Peters, U., 1 Jan 2019, In : Nature Genetics. 51, 1, p. 76-87 12 p.

Research output: Contribution to journalArticle

Open Access
File
42 Citations (Scopus)
238 Downloads (Pure)

Drug-induced chromatin accessibility changes associate with sensitivity to liver tumor promotion

Vitobello, A., Perner, J., Beil, J., Zhu, J., Del Río-Espínola, A., Morawiec, L., Westphal, M., Dubost, V., Altorfer, M., Naumann, U., Mueller, A., Kapur, K., Borowsky, M., Henderson, C., Wolf, C. R., Schwarz, M., Moggs, J. & Terranova, R., Oct 2019, In : Life Science Alliance. 2, 5, p. 1-18 18 p., e201900461.

Research output: Contribution to journalArticle

Open Access
File
69 Downloads (Pure)
2018

Cytochrome b5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b5 /P450 reductase null (HBRN) mice

Reed, L., Mrizova, I., Barta, F., Indra, R., Moserova, M., Kopka, K., Schmeiser, H. H., Wolf, C. R., Henderson, C. J., Stiborova, M., Phillips, D. H. & Arlt, V. M., Apr 2018, In : Archives of Toxicology. 92, 4, p. 1625-1638 14 p.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
138 Downloads (Pure)

Identification of novel pathways of osimertinib disposition and potential implications for the outcome of lung cancer therapy

MacLeod, A. K., Lin, D., Huang, J. T-J., McLaughlin, L. A., Henderson, C. J. & Wolf, C. R., May 2018, In : Clinical Cancer Research. 24, 9, p. 2138-2147 10 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
144 Downloads (Pure)

Interaction between polymorphisms in aspirin metabolic pathways, regular aspirin use and colorectal cancer risk: A case-control study in unselected white European populations

Sheth, H., Northwood, E., Ulrich, C. M., Scherer, D., Elliott, F., Barrett, J. H., Forman, D., Wolf, C. R., Smith, G., Jackson, M. S., Santibanez-Koref, M., Haile, R., Casey, G., Jenkins, M., Win, A. K., Hopper, J. L., Marchand, L. L., Lindor, N. M., Thibodeau, S. N., Potter, J. D. & 2 others, Burn, J. & Bishop, D. T., 9 Feb 2018, In : PLoS ONE. 13, 2, p. 1-17 17 p., e0192223.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
179 Downloads (Pure)

Measuring in vivo responses to endogenous and exogenous oxidative stress using a novel haem oxygenase 1 reporter mouse

McMahon, M., Ding, S., Acosta-Jimenez, L. P., Frangova, T. G., Henderson, C. J. & Wolf, C. R., 1 Jan 2018, In : Journal of Physiology. 596, 1, p. 105-127 23 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
97 Downloads (Pure)
2017
Open Access
File
5 Citations (Scopus)
114 Downloads (Pure)

Aryl hydrocarbon receptor is required for optimal B-cell proliferation

Villa, M., Gialitakis, M., Tolaini, M., Ahlfors, H., Henderson, C. J., Wolf, C. R., Brink, R. & Stockinger, B., 4 Jan 2017, In : EMBO Journal. 36, 1, p. 116-128 13 p.

Research output: Contribution to journalArticle

Open Access
File
26 Citations (Scopus)
194 Downloads (Pure)

Corrigendum to "Aldo-keto reductases are biomarkers of NRF2 activity and are co-ordinately overexpressed in non-small cell lung cancer"

MacLeod, A. K., Acosta-Jimenez, L., Coates, P. J., McMahon, M., Carey, F. A., Honda, T., Hayes, J. D., Henderson, C. J. & Wolf, C. R., 22 Aug 2017, In : British Journal of Cancer. 117, 1 p., e1.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Feedback control of AHR signalling regulates intestinal immunity

Schiering, C., Wincent, E., Metidji, A., Iseppon, A., Li, Y., Potocnik, A. J., Omenetti, S., Henderson, C. J., Wolf, C. R., Nebert, D. W. & Stockinger, B., 9 Feb 2017, In : Nature. 542, 7640, p. 242-245 4 p.

Research output: Contribution to journalLetter

Open Access
File
121 Citations (Scopus)
185 Downloads (Pure)

Genetically Humanized Animal Models

Samuelsson, K., Scheer, N., Wilson, I., Wolf, C. & Henderson, C. J., 13 Jun 2017, Comprehensive Medicinal Chemistry III. Chackalamannil, S., Rotella, D. P. & Ward, S. E. (eds.). Elsevier, p. 130-149 20 p. (Reference Module in Chemistry, Molecular Sciences and Chemical Engineering).

Research output: Chapter in Book/Report/Conference proceedingChapter

Open Access
File
13 Citations (Scopus)
114 Downloads (Pure)

Progress in identifying epigenetic mechanisms of xenobiotic-induced non-genotoxic carcinogenesis

Terranova, R., Vitobello, A., Del Rio Espinola, A., Wolf, C. R., Schwarz, M., Thomson, J. M., Meehan, R. & Moggs, J. G., Apr 2017, In : Current Opinion in Toxicology. 3, p. 62-70 9 p.

Research output: Contribution to journalReview article

7 Citations (Scopus)

Xenobiotic CAR activators induce Dlk1-Dio3 locus non-coding RNA expression in mouse liver

Pouché, L., Vitobello, A., Römer, M., Glogovac, M., MacLeod, A. K., Ellinger-Ziegelbauer, H., Westphal, M., Dubost, V., Stiehl, D. P., Dumotier, B., Fekete, A., Moulin, P., Zell, A., Schwarz, M., Moreno, R., Huang, J. T. J., Elcombe, C. R., Henderson, C. J., Wolf, C. R., Moggs, J. G. & 1 others, Terranova, R., Aug 2017, In : Toxicological Sciences. 158, 2, p. 367-378 11 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
159 Downloads (Pure)
2016

Aldo-keto reductases are biomarkers of NRF2 activity and are co-ordinately overexpressed in non-small cell lung cancer

MacLeod, A. K., Acosta-Jimenez, L., Coates, P. J., McMahon, M., Carey, F. A., Honda, T., Henderson, C. J. & Wolf, C. R., 6 Dec 2016, In : British Journal of Cancer. 115, 12, p. 1530-1539 10 p.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
206 Downloads (Pure)

Application of Humanised and Other Transgenic Models to Predict Human Responses to Drugs

Wolf, C. R., Kapelyukh, Y., Scheer, N. & Henderson, C. J., 20 Nov 2016, New Horizons in Predictive drug Metabolism and Pharmocokentics. 49 ed. Royal Society of Chemistry, Vol. 2016-January. p. 152-176 25 p. (RSC Drug Discovery Series; vol. 2016-January, no. 49).

Research output: Chapter in Book/Report/Conference proceedingChapter

Attenuation of lung fibrosis in mice with a clinically relevant inhibitor of glutathione-S-transferase π

McMillan, D. H., van der Velden, J. L. J., Lahue, K. G., Quan, X., Schneider, R. W., Iberg, M. S., Nolin, J. D., Abdalla, S., Casey, D. T., Tew, K. D., Townsend, D. M., Henderson, C. J., Wolf, C. R., Butnor, K. J., Taatjes, D. J., Budd, R. C., Irvin, C. G., van der Vliet, A., Flemer, S., Anathy, V. & 1 others, Janssen-Heininger, Y. M. W., 2 Jun 2016, In : JCI Insight. 1, 8, 16 p., e85717.

Research output: Contribution to journalArticle

Open Access
File
175 Downloads (Pure)

Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans

Takahashi, S., Fukami, T., Masuo, Y., Brocker, C. N., Xie, C., Krausz, K. W., Wolf, C. R., Henderson, C. J. & Gonzalez, F. J., Dec 2016, In : Journal of Lipid Research. 57, p. 2130-2037 8 p.

Research output: Contribution to journalArticle

Open Access
File
64 Citations (Scopus)
193 Downloads (Pure)

Loss of Tet1-associated 5-hydroxymethylcytosine is concomitant with aberrant promoter hypermethylation in liver cancer

Thomson, J. P., Ottaviano, R., Unterberger, E. B., Lempiäinen, H., Muller, A., Terranova, R., Illingworth, R. S., Webb, S., Kerr, A. R. W., Lyall, M. J., Drake, A. J., Wolf, C. R., Moggs, J. G., Schwarz, M. & Meehan, R. R., 15 May 2016, In : Cancer Research. 76, 10, p. 3097-3108 12 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Olaparib, monotherapy or with ionizing radiation, exacerbates DNA damage in normal tissues: insights from a new p21 reporter mouse

McMahon, M., Frangova, T. G., Henderson, C. J. & Wolf, C. R., Dec 2016, In : Molecular Cancer Research. 14, 12, p. 1195-1203 9 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
338 Downloads (Pure)

The role of protein-protein and protein-membrane Interactions on P450 function

Scott, E. E., Wolf, C. R., Otyepka, M., Humphreys, S. C., Reed, J. R., Henderson, C. J., McLaughlin, L. A., Paloncyova, M., Navratilova, V., Berka, K., Anzenbacher, P., Dahal, U. P., Barnaba, C., Brozik, J. A., Jones, J. P., Estrada, F., Laurence, J. S., Park, J. W. & Backes, W. L., Apr 2016, In : Drug Metabolism and Disposition. 44, 4, p. 576-590 15 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2015

Activation status of the Pregnane X Receptor influences Vemurafenib availability in humanized mouse models

MacLeod, A. K., McLaughlin, L. A., Henderson, C. J. & Wolf, C. R., 1 Nov 2015, In : Cancer Research. 75, 21, p. 4573-4581 10 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
22 Citations (Scopus)

An enhanced in vivo stable isotope labeling by amino acids in cell culture (SILAC) model for quantification of drug metabolism enzymes

MacLeod, A. K., Fallon, P. G., Sharp, S., Henderson, C. J., Wolf, C. R. & Huang, J. T-J., Mar 2015, In : Molecular & Cellular Proteomics. 14, 3, p. 750-760 11 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
Open Access
File
10 Citations (Scopus)
49 Downloads (Pure)

Cytochrome b5 is a major determinant of human cytochrome P450 CYP2D6 and CYP3A4 activity in vivo

Henderson, C. J., McLaughlin, L. A., Scheer, N., Stanley, L. A. & Wolf, C. R., Apr 2015, In : Molecular Pharmacology. 87, 4, p. 733-739 7 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Defining human pathways of drug metabolism in vivo through the development of a multiple humanized mouse model

Scheer, N., Kapelyukh, Y., Rode, A., Oswald, S., Busch, D., McLaughlin, L. A., Lin, D., Henderson, C. J. & Wolf, C. R., Nov 2015, In : Drug Metabolism and Disposition. 43, 11, p. 1679-1690 12 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Evidence that the capacity of nongenotoxic carcinogens to induce oxidative stress is subject to marked variability

Henderson, C. J., Cameron, A. R., Chatham, L., Stanley, L. A. & Wolf, C. R., May 2015, In : Toxicological Sciences. 145, 1, p. 138-148 11 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

MicroRNA-224 is associated with colorectal cancer progression and response to 5-fluorouracil-based chemotherapy by KRAS-dependent and-independent mechanisms

Amankwatia, E. B., Chakravarty, P., Carey, F. A., Weidlich, S., Steele, R. J. C., Munro, A. J., Wolf, C. R. & Smith, G., 28 Apr 2015, In : British Journal of Cancer. 112, 9, p. 1480-1490 11 p.

Research output: Contribution to journalArticle

46 Citations (Scopus)

Model systems for understanding mechanisms of non-genotoxic carcinogenesis: response

Braeuning, A., Henderson, C. J., Wolf, C. R. & Schwarz, M., Oct 2015, In : Toxicological Sciences. 147, 2, p. 299-300 2 p.

Research output: Contribution to journalLetter

5 Citations (Scopus)

Proteome-wide identification and quantification of S-glutathionylation targets in mouse liver

McGarry, D. J., Chen, W., Chakravarty, P., Lamont, D. L., Wolf, C. R. & Henderson, C. J., Jun 2015, In : Biochemical Journal. 469, 1, p. 25-32 8 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Recurrent Coding Sequence Variation Explains only A Small Fraction of the Genetic Architecture of Colorectal Cancer

Timofeeva, M. N., Kinnersley, B., Farrington, S. M., Whiffin, N., Palles, C., Svinti, V., Lloyd, A., Gorman, M., Ooi, L. Y., Hosking, F., Barclay, E., Zgaga, L., Dobbins, S., Martin, L., Theodoratou, E., Broderick, P., Tenesa, A., Smillie, C., Grimes, G., Hayward, C. & 41 others, Campbell, A., Porteous, D., Deary, I. J., Harris, S. E., Northwood, E. L., Barrett, J. H., Smith, G., Wolf, R., Forman, D., Morreau, H., Ruano, D., Tops, C., Wijnen, J., Schrumpf, M., Boot, A., Vasen, H. F. A., Hes, F. J., Van Wezel, T., Franke, A., Lieb, W., Schafmayer, C., Hampe, J., Buch, S., Propping, P., Hemminki, K., Försti, A., Westers, H., Hofstra, R., Pinheiro, M., Pinto, C., Teixeira, M., Ruiz-Ponte, C., Fernández-Rozadilla, C., Carracedo, A., Castells, A., Castellví-Bel, S., Campbell, H., Bishop, D. T., Tomlinson, I. P. M., Dunlop, M. G. & Houlston, R. S., 10 Nov 2015, In : Scientific Reports. 5, 10 p., 16286.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
145 Downloads (Pure)
11 Citations (Scopus)
2014

A role for cytochrome b5 in the in vivo disposition of anti-cancer and cytochrome P450 probe drugs in mice

Henderson, C. J., McLaughlin, L. A., Finn, R. D., Ronseaux, S., Kapelyukh, Y. & Wolf, C. R., Jan 2014, In : Drug Metabolism and Disposition. 42, 1, p. 70-77 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

A Targeted in Vivo SILAC Approach for Quantification of Drug Metabolism Enzymes: Regulation by the Constitutive Androstane Receptor

Macleod, A. K., Zang, T., Riches, Z., Henderson, C. J., Wolf, C. R. & Huang, J. T-J., 7 Feb 2014, In : Journal of Proteome Research. 13, 2, p. 866-874 9 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
92 Downloads (Pure)

Cytochrome b5 and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditions

Stiborová, M., Moserová, M., Černá, V., Indra, R., Dračínský, M., Šulc, M., Henderson, C. J., Wolf, C. R., Schmeiser, H. H., Phillips, D. H., Frei, E. & Arlt, V. M., 6 Apr 2014, In : Toxicology. 318, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Deletion of 30 Murine Cytochrome p450 Genes Results In Viable Mice With Compromised Drug Metabolism

Scheer, N., McLaughlin, L. A., Rode, A., MacLeod, A. K., Henderson, C. J. & Wolf, C. R., Jun 2014, In : Drug Metabolism and Disposition. 42, 6, p. 1022-1030 9 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Epigenetic profiles as defined signatures of xenobiotic exposure

Thomson, J. P., Moggs, J. G., Wolf, C. R. & Meehan, R. R., Apr 2014, In : Mutation Research: Genetic Toxicology and Environmental Mutagenesis. 764-765, p. 3-9 7 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Glutathione S-transferase P1 (GSTP1) directly influences platinum drug chemosensitivity in ovarian tumour cell lines

Sawers, L., Ferguson, M. J., Ihrig, B. R., Young, H. C., Chakravarty, P., Wolf, C. R. & Smith, G., 9 Sep 2014, In : British Journal of Cancer. 111, 6, p. 1150-1158 9 p.

Research output: Contribution to journalArticle

Open Access
File
43 Citations (Scopus)
180 Downloads (Pure)

HDAC inhibitors increase NRF2-signaling in tumour cells and blunt the efficacy of co-adminstered cytotoxic agents

McMahon, M., Campbell, K. H., MacLeod, A. K., McLaughlin, L. A., Henderson, C. J. & Wolf, C. R., 26 Nov 2014, In : PLoS ONE. 9, 11, e114055.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
159 Downloads (Pure)

In vivo regulation of human glutathione transferase GSTP by chemopreventive agents

Henderson, C. J., McLaren, A. W. & Wolf, C. R., 15 Aug 2014, In : Cancer Research. 74, 16, p. 4378-4387 10 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane X receptors

Luisier, R., Lempiäinen, H., Scherbichler, N., Braeuning, A., Geissler, M., Dubost, V., Müller, A., Scheer, N., Chibout, S-D., Hara, H., Picard, F., Theil, D., Couttet, P., Vitobello, A., Grenet, O., Grasl-Kraupp, B., Ellinger-Ziegelbauer, H., Thomson, J. P., Meehan, R. R., Elcombe, C. R. & 6 others, Henderson, C. J., Wolf, C. R., Schwarz, M., Moulin, P., Terranova, R. & Moggs, J. G., 2014, In : Toxicological Sciences. 139, 2, p. 501-511 11 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Phenobarbital-mediated tumor promotion in transgenic mice with humanized CAR and PXR

Braeuning, A., Gavrilov, A., Brown, S., Wolf, C. R., Henderson, C. J. & Schwarz, M., 1 Aug 2014, In : Toxicological Sciences. 140, 2, p. 259-70 12 p.

Research output: Contribution to journalArticle

Open Access
File
40 Citations (Scopus)
156 Downloads (Pure)
2013

Cytochrome P450 CYP1B1 interacts with 8-methoxypsoralen (8-MOP) and influences psoralen-ultraviolet (PUVA) sensitivity

Deeni, Y. Y., Ibbotson, S. H., Woods, J. A., Wolf, C. R. & Smith, G., 2013, In : PLoS ONE. 8, 9, e75494.

Research output: Contribution to journalArticle

8 Citations (Scopus)
38 Citations (Scopus)