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• Article

  Vegetation changes and water cycle in a changing environment

  Wang, L., Wei, X., Bishop, K., Reeves, A. D., Ursino, N. & Winkler, R., 8 Mar 2018, In: Hydrology and Earth System Sciences. 22, 3, p. 1731-1734 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  5 Citations (Scopus)

  174 Downloads (Pure)

• veqtl-mapper: variance association mapping for molecular phenotypes

  Brown, A. A., 1 Sep 2017, In: Bioinformatics. 33, 17, p. 2772-2773 2 p.

  Research output: Contribution to journal › Article › peer-review

  • Phenotype
  • Gene expression
  • Gene Expression
  • Locus
  • Signature
  2 Citations (Scopus)

• Versatility of a localized surface plasmon resonance-based gold nanoparticle-alloyed quantum dot nanobiosensor for immunofluorescence detection of viruses

  Takemura, K., Adegoke, O., Takahashi, N., Kato, T., Li, T-C., Kitamoto, N., Tanaka, T., Suzuki, T. & Park, E. Y., 15 Mar 2017, In: Biosensors and Bioelectronics. 89, Pt 2, p. 998-1005 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Surface plasmon resonance
  • Gold nanoparticles
  • Quantum Dots
  • Semiconductor quantum dots
  • Surface Plasmon Resonance
  63 Citations (Scopus)

• Vertical capacity of grillage foundations in sand

  Bransby, M. F., Brown, M. J., Knappett, J. A., Hudacsek, P., Morgan, N., Cathie, D., Maconochie, A., Yun, G., Ripley, A. G., Brown, N. & Egborge, R., Aug 2011, In: Canadian Geotechnical Journal. 48, 8, p. 1246-1265 20 p.

  Research output: Contribution to journal › Article › peer-review
  10 Citations (Scopus)

• Vertical schooling and learning transformations in curriculum research: points and counterpoints in outdoor education and sustainability

  Truong, S., Singh, M., Reid, C., Gray, T. & Ward, K., Sep 2018, In: Curriculum Perspectives. 38, 2, p. 181-186 6 p.

  Research output: Contribution to journal › Article › peer-review

  • curriculum research
  • sustainability
  • environmental damage
  • curriculum
  • learning
  2 Citations (Scopus)

• Very low levels of atherogenic lipoproteins and the risk for cardiovascular events: a meta-analysis of statin trials

  Boekholdt, S. M., Hovingh, G. K., Mora, S., Arsenault, B. J., Amarenco, P., Pedersen, T. R., LaRosa, J. C., Waters, D. D., DeMicco, D. A., Simes, R. J., Keech, A. C., Colquhoun, D., Hitman, G. A., Betteridge, D. J., Clearfield, M. B., Downs, J. R., Colhoun, H. M., Gotto, A. M., Ridker, P. M., Grundy, S. M. & 1 others, Kastelein, J. J. P., 5 Aug 2014, In: Journal of the American College of Cardiology. 64, 5, p. 485-494 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Lipoproteins
  • Meta-Analysis
  • LDL Cholesterol
  • lipoprotein cholesterol
  348 Citations (Scopus)

• Vessel Health and Preservation Framework: Use of the outcome logic model for evaluation

  Burnett, E., Hallam, C., Curran, E. T. & Weston, V., 1 Sep 2018, In: Journal of Infection Prevention. 19, 5, p. 228-234 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Health
  • Veins
  • Patient Care Management
  • Vascular Access Devices
  • Patient Care Team
  2 Citations (Scopus)

• Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs

  Giordani, F., Paape, D., Vincent, I. M., Pountain, A. W., Fernández-Cortés, F., Rico, E., Zhang, N., Morrison, L. J., Freund, Y., Witty, M. J., Peter, R., Edwards, D. Y., Wilkes, J. M., van der Hooft, J. J. J., Regnault, C., Read, K. D., Horn, D., Field, M. C. & Barrett, M. P., 3 Nov 2020, In: PLoS Pathogens. 16, 11, 20 p., e1008932.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • AN11736
  • Carboxypeptidases
  • Prodrugs
  • Peptide Hydrolases
  • Trypanosoma congolense
  7 Downloads (Pure)

• VEX1 controls the allelic exclusion required for antigenic variation in trypanosomes

  Glover, L., Hutchinson, S., Alsford, S. & Horn, D., 28 Jun 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 26, p. 7225-7230 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Antigenic Variation
  • Trypanosoma
  • Membrane Glycoproteins
  • RNA Polymerase I
  • Immune Evasion
  44 Citations (Scopus)

  415 Downloads (Pure)

• VgrG and PAAR Proteins Define Distinct Versions of a Functional Type VI Secretion System

  Cianfanelli, F. R., Alcoforado Diniz, J., Guo, M., De Cesare, V., Trost, M. & Coulthurst, S., 28 Jun 2016, In: PLoS Pathogens. 12, 6, 27 p., e1005735.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Type VI Secretion Systems
  • Proteins
  • Serratia marcescens
  • Weapons
  • Protein Domains
  74 Citations (Scopus)

  226 Downloads (Pure)

• Vibigaba (germinated brown rice) and maintenance of long-term normal blood glucose concentration: evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006

  EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) & Willatts, P., 1 Jul 2017, In: EFSA Journal. 15, 7, e04916.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • health claims
  • brown rice
  • Oryza
  • blood glucose
  • Blood Glucose
  53 Downloads (Pure)

• Vibigaba (germinated brown rice) and maintenance of normal blood cholesterol concentration: evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006

  EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) & Willatts, P., 1 Jul 2017, In: EFSA Journal. 15, 7, e04913.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • health claims
  • brown rice
  • Oryza
  • cholesterol
  • Cholesterol
  51 Downloads (Pure)

• Vibigaba (germinated brown rice) and maintenance of normal blood pressure: evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006

  EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) & Willatts, P., 1 Jul 2017, In: EFSA Journal. 15, 7, e04914.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • health claims
  • brown rice
  • Oryza
  • blood pressure
  • Maintenance
  52 Downloads (Pure)

• Vibigaba (germinated brown rice) and reduction of body weight in the context of an energy-restricted diet: evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006

  EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) & Willatts, P., 1 Jul 2017, In: EFSA Journal. 15, 7, e04915.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • health claims
  • low calorie diet
  • brown rice
  • Oryza
  • Body Weight
  3 Citations (Scopus)

  59 Downloads (Pure)

• Vibrational spectra and structures of the anions of urazole and 4-methylurazole: DFT calculations of the normal modes and the influence of hydrogen bonding

  Ryall, J. P., Dines, T. J., Chowdhry, B. Z., Leharne, S. A. & Withnall, R., Mar 2011, In: Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 78, 3, p. 918-925 8 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Vibrational spectroscopy and DFT calculations of N,N '-dicyclohexylcarbodiimide

  Chowdhry, B. Z., Dines, T. J., Leharne, S. A., Ryall, J. P., Shadi, I. T. & Withnall, R., Feb 2011, In: Journal of Raman Spectroscopy. 42, 2, p. 230-238 9 p.

  Research output: Contribution to journal › Article › peer-review
  2 Citations (Scopus)

• Video Interaction Guidance in Collaborative Group Work: Impact on Primary School Pupils' Self-Esteem and Behaviours

  Musset, M. & Topping, K., 21 Oct 2017, In: Educational Psychology. 37, 9, p. 1067-1081 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • primary school pupil
  • Pupil
  • group work
  • Self Concept
  • self-esteem
  2 Citations (Scopus)

  329 Downloads (Pure)

• Videolaryngoscopy to teach neonatal intubation: A randomized trial

  O'Shea, J. E., Thio, M., Omar Kamlin, C., McGrory, L., Wong, C., John, J., Roberts, C., Kuschel, C. & Davis, P. G., 1 Nov 2015, In: Pediatrics. 136, 5, p. 912-919 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Intubation
  • Delivery Rooms
  • Neonatal Intensive Care
  • Premedication
  • Intratracheal Intubation
  63 Citations (Scopus)

• Videotaping of surgical procedures and outcomes following extraperitoneal laparoscopic radical prostatectomy for clinically localised prostate cancer

  Paterson, C., McLuckie, S., Yew-Fung, C., Tang, B., Laing, S. & Nabi, G., 13 Dec 2016, In: Journal of Surgical Oncology. 114, 8, p. 1016-1023 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Prostatectomy
  • Prostatic Neoplasms
  • Peer Review
  • Margins of Excision
  • Video Recording
  4 Citations (Scopus)

  187 Downloads (Pure)

• Viewpoint: Availability of oestrogen receptor and HER2 status for the breast multidisciplinary meeting discussion; time to get it right

  Francis, A., Bartlett, J., Rea, D., Pinder, S. E., Stein, R. C., Stobart, H., Purdie, C. A., Rakha, E., Thompson, A., Shaaban, A. M. & Translational Subgroup of the NCRI Breast Clinical Studies Group, 1 Jul 2016, In: European Journal of Surgical Oncology. 42, 7, p. 994-998 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Estrogen Receptors
  • Breast
  • Decision Making
  • Anxiety
  • Therapeutics
  4 Citations (Scopus)

• Vignette development and administration: A framework for protecting research participants

  Bradbury-Jones, C., Taylor, J. & Herber, O. R., 2012, In: International Journal of Social Research Methodology.

  Research output: Contribution to journal › Article › peer-review

  • health care
  • social research
  • trauma
  • research method
  • best practice
  27 Citations (Scopus)

• Vilhelm Lundstedt’s ‘Legal Machinery’ and the Demise of Juristic Practice

  Siliquini-Cinelli, L., Jul 2018, In: Law and Critique. 29, 2, p. 241-264 24 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • scientification
  • jurist
  • legal profession
  • school law
  • social construction
  1 Citation (Scopus)

  148 Downloads (Pure)

• Vincent Goodstadt and Kevin Murray — The 21st Century Challenges for Planning

  Goodstadt, V. & Murray, K., 3 Apr 2017, In: DisP. 53, 2, p. 64-65 2 p.

  Research output: Contribution to journal › Article › peer-review

• Viral DNA Binding Protein SUMOylation Promotes PML Nuclear Body Localization Next to Viral Replication Centers

  Stubbe, M., Mai, J., Paulus, C., Stubbe, H. C., Berscheminski, J., Karimi, M., Hofmann, S., Weber, E., Hadian, K., Hay, R., Groitl, P., Nevels, M., Dobner, T. & Schreiner, S., 17 Mar 2020, In: MBio. 11, 2, 21 p., e00049-20.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Sumoylation
  • Viral DNA
  • DNA-Binding Proteins
  • Human Adenoviruses
  • Viral Proteins
  3 Citations (Scopus)

  30 Downloads (Pure)

• Viral etiology and the impact of co-detection in young children presenting with influenza-like illness

  Lim, F. J., Wake, Z. V., Levy, A., Tempone, S., Moore, H. C., Richmond, P. C., de Klerk, N., Conway, N., Keil, A. D., Effler, P. V., Smith, D. W. & Blyth, C. C., 1 Sep 2016, In: Journal of the Pediatric Infectious Disease Society. 6, 3, p. 260-266 7 p., piw042.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Human Influenza
  • Child
  • Viruses
  • Respiratory Tract Infections
  • Hospitalization
  6 Citations (Scopus)

  159 Downloads (Pure)

• Viral hepatitis prevalence in patients with active and latent tuberculosis

  Nooredinvand, H. A., Connell, D. W., Asgheddi, M., Abdullah, M., O'Donoghue, M., Campbell, L., Wickremasinghe, M. I., Lalvani, A., Kon, O. M. & Khan, S. A., 7 Aug 2015, In: World Journal of Gastroenterology . 21, 29, p. 8920-8926 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Latent Tuberculosis
  • Hepatitis
  • Tuberculosis
  • Hepatitis B virus
  • Hepacivirus
  11 Citations (Scopus)

  122 Downloads (Pure)

• Viral interference with host mRNA surveillance, the nonsense-mediated mRNA decay (NMD) pathway, through a new function of HTLV-1 Rex: implications for retroviral replication

  Nakano, K., Ando, T., Yamagishi, M., Yokoyama, K., Ishida, T., Ohsugi, T., Tanaka, Y., Brighty, D. W. & Watanabe, T., Jun 2013, In: Microbes and Infection. 15, 6-7, p. 491-505 15 p.

  Research output: Contribution to journal › Article › peer-review
  39 Citations (Scopus)

• Virtual Casting of Stab Wounds in Cartilage Using Micro-Computed Tomography

  Pounder, D. J. & Sim, L. J., Jun 2011, In: American Journal of Forensic Medicine and Pathology. 32, 2, p. 97-99 3 p.

  Research output: Contribution to journal › Article › peer-review
  16 Citations (Scopus)

• Virtual reality haptic dissection

  Erolin, C., Wilkinson, C. & Soames, R., Dec 2011, In: Journal of Visual Communication in Medicine. 34, 4, p. 193-199 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Virtual Reality
  • Haptics
  • Dissection
  • Software
  • Anatomy
  2 Citations (Scopus)

• Virtual reality haptic human dissection. Medicine Meets Virtual Reality 18

  Erolin, C., Wilkinson, C. & Soames, R., 2011, In: Studies in Health Technology and Informatics . 163, p. 397-9

  Research output: Contribution to journal › Article › peer-review

• Virtual Reality Relaxation to Decrease Dental Anxiety: Immediate Effect Randomized Clinical Trial

  Lahti, S., Suominen, A., Freeman, R., Lahteenoja, T. & Humphris, G., 1 Oct 2020, In: JDR Clinical & Translational Research . 5, 4, p. 312-318 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Dental Anxiety
  • Virtual Reality
  • Randomized Controlled Trials
  • Dental Care
  • Oral Health
  24 Downloads (Pure)

• Virtue, progress and practice

  Loughlin, M., Bluhm, R., Buetow, S., Upshur, R. E. G., Goldenberg, M. J., Borgerson, K. & Entwistle, V., Oct 2011, In: Journal of Evaluation in Clinical Practice. 17, 5, p. 839-846 8 p.

  Research output: Contribution to journal › Article › peer-review
  8 Citations (Scopus)

• Viruses and disease: emerging concepts for prevention, diagnosis and treatment

  Herrington, C. S., Coates, P. J. & Duprex, W. P., Jan 2015, In: Journal of Pathology. 235, 2, p. 149-152 4 p.

  Research output: Contribution to journal › Article

  • Virology
  • Virus Diseases
  • Acute Disease
  • Viruses
  • Pathology
  10 Citations (Scopus)

• Visible thyroid ectopia

  Yeap, P. M., Attaie, M., Jones, J., Maroo, S. & Donaldson, M., Nov 2012, In: Archives of Disease in Childhood. Fetal and Neonatal edition. 97, 6

  Research output: Contribution to journal › Article › peer-review

• Vision and Precarity in Marjane Satrapi's Persepolis

  Nabizadeh, G., 2016, In: WSQ: Women's Studies Quarterly. 44, 1/2, p. 152-167 16 p.

  Research output: Contribution to journal › Article › peer-review

• Vision screening in children: a retrospective study of social and demographic factors with regard to visual outcomes

  O'Colmain, U., Low, L., Gilmour, C. & MacEwen, C. J., Aug 2016, In: British Journal of Ophthalmology. 100, 8, p. 1109-1113 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Vision Screening
  • Retrospective Studies
  • Demography
  • Child
  • Orthoptics
  8 Citations (Scopus)

  179 Downloads (Pure)

• Visit-to-visit HbA_1c variability is associated with cardiovascular disease and microvascular complications in patients with newly diagnosed type 2 diabetes

  Li, S., Nemeth, I., Donnelly, L., Hapca, S., Zhou, K. & Pearson, E., 20 Jan 2020, In: Diabetes Care. 43, 2, p. 426-432 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Type 2 Diabetes Mellitus
  • Cardiovascular Diseases
  • Diabetic Foot
  • Diabetic Neuropathies
  • Peripheral Nervous System Diseases
  9 Citations (Scopus)

  179 Downloads (Pure)

• Visual feature binding in younger and older adults: encoding and suffix interference effects

  Brown, L. A., Niven, E. H., Logie, R. H., Rhodes, S. & Allen, R. J., 7 Feb 2017, In: Memory. 25, 2, p. 261-275 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • benzoylprop-ethyl
  • Encoding
  • Interference
  • Young Adult
  • Memory
  16 Citations (Scopus)

  219 Downloads (Pure)

• Visual impairment is associated with physical and mental comorbidities in older adults: a cross-sectional study

  Court, H., McLean, G., Guthrie, B., Mercer, S. W. & Smith, D. J., 17 Oct 2014, In: BMC Medicine. 12, 8 p., 181.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Vision Disorders
  • Comorbidity
  • Cross-Sectional Studies
  • Mental Health
  • Health
  78 Citations (Scopus)

  161 Downloads (Pure)

• Visual information about object size and object position are retained differently in the visual brain: Evidence from grasping studies

  Hesse, C., Miller, L. & Buckingham, G., Oct 2016, In: Neuropsychologia. 91, p. 531-543

  Research output: Contribution to journal › Article › peer-review
  12 Citations (Scopus)

• Visual inspection for caries detection: a systematic review and meta-analysis

  Gimenez, T., Piovesan, C., Braga, M. M., Raggio, D. P., Deery, C., Ricketts, D. N., Ekstrand, K. R. & Mendes, F. M., Jul 2015, In: Journal of Dental Research. 94, 7, p. 895-904 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Meta-Analysis
  • Systematic Reviews
  • Publication Bias
  • Deciduous Tooth
  • Manuscripts
  82 Citations (Scopus)

• Visualisation techniques to support public interpretation of future climate change and land-use choices: a case study from N-E Scotland

  Wang, C., Miller, D., Brown, I., Jiang, Y. & Castellazzi, M., 2 Jun 2016, In: International Journal of Digital Earth. 9, 6, p. 586-605 20 p.

  Research output: Contribution to journal › Article › peer-review

  • Land use
  • Climate change
  • visualization
  • Visualization
  • public
  7 Citations (Scopus)

• Visualising risk in Pat Grant’s Blue: Xenophobia and graphic narrative

  Nabizadeh, G., 2017, In: Textual Practice. 31, 3, p. 537-552 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Graphic Narrative
  • Xenophobia
  • Graphic Novel
  • Racism
  • Nostalgia
  1 Citation (Scopus)

  172 Downloads (Pure)

• Visualization and biochemical analyses of the emerging mammalian 14-3-3-phosphoproteome

  Johnson, C., Tinti, M., Wood, N. T., Campbell, D. G., Toth, R., Dubois, F., Geraghty, K. M., Wong, B. H. C., Brown, L. J., Tyler, J., Gernez, A., Chen, S., Synowsky, S. & MacKintosh, C., Oct 2011, In: Molecular & Cellular Proteomics. 10, 10, p. - 15 p.

  Research output: Contribution to journal › Article › peer-review
  53 Citations (Scopus)

• Visualization of Biomedical Data

  O'Donoghue, S. I., Baldi, B. F., Clark, S. J., Darling, A. E., Hogan, J. M., Kaur, S., Maier-Hein, L., McCarthy, D. J., Moore, W., Stenau, E., Swedlow, J., Vuong, J. & Procter, J., 20 Jul 2018, In: Annual Review of Biomedical Data Science. 1

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • visualization
  • computer scientist
  • communicator
  • biomedical research
  • surgery

• Visualization of podocyte substructure with structured illumination microscopy (SIM): A new approach to nephrotic disease

  Pullman, J. M., Nylk, J., Campbell, E. C., Gunn-Moore, F. J., Prystowsky, M. B. & Dholakia, K., 1 Feb 2016, In: Biomedical Optics Express. 7, 2, p. 302-311 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Podocytes
  • NPHS2 protein
  • Lighting
  • substructures
  • electron microscopy
  11 Citations (Scopus)

• Visualization of the Serratia type VI secretion system reveals unprovoked attacks and dynamic assembly

  Gerc, A. J., Diepold, A., Trunk, K., Porter, M., Rickman, C., Armitage, J. P., Stanley-Wall, N. R. & Coulthurst, S. J., 29 Sep 2015, In: Cell Reports. 12, 12, p. 2131-2142 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Type VI Secretion Systems
  • Serratia
  • Machinery
  • Fires
  • Visualization
  38 Citations (Scopus)

  275 Downloads (Pure)

• Visualizing the invisible: applying an arts-based methodology to explore how healthcare workers and patient representatives envisage pathogens in the context of healthcare associated infections

  Macduff, C., Wood, F. K., Hackett, C., McGhee, J., Loudon, D., Macdonald, A., Dancer, S. & Karcher, A., 2014, In: Arts and Health. 6, 2, p. 117-131 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Health Care Workers
  • Patient Advocacy
  • Art
  • Cross Infection
  • Infection
  7 Citations (Scopus)

• Visualizing ultrasonically induced shear wave propagation using phase-sensitive optical coherence tomography for dynamic elastography

  Nguyen, T-M., Song, S., Arnal, B., Huang, Z., O'Donnell, M. & Wang, R. K., 15 Feb 2014, In: Optics Letters. 39, 4, p. 838-841 4 p.

  Research output: Contribution to journal › Article › peer-review

  • S waves
  • wave propagation
  • tomography
  • shear
  • radiation
  60 Citations (Scopus)

• Visual melancholy in Shaun Tan’s The Arrival

  Nabizadeh, G., 3 Sep 2014, In: Journal of Graphic Novels and Comics. 5, 3, p. 366-379 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Melancholy
  • Colour Scheme
  • Nostalgia
  • Photography
  • Mimicry
  3 Citations (Scopus)