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  • Lindsay Spender
2020

Multifaceted transforming growth factor-beta (TGFβ) signalling in glioblastoma

Birch, J. L., Coull, B. J., Spender, L. C., Watt, C., Willison, A., Syed, N., Chalmers, A. J., Hossain-Ibrahim, M. K. & Inman, G. J., 19 Apr 2020, In : Cellular Signalling. 72, p. 1-12 12 p., 109638.

Research output: Contribution to journalReview article

2019

Preclinical Evaluation of AZ12601011 and AZ12799734, Inhibitors of Transforming Growth Factor β Superfamily Type 1 Receptors.

Spender, L. C., Ferguson, G. J., Hughes, G. D., Davies, B. R., Goldberg, F. W., Herrera, B., Taylor, R. G., Strathearn, L., Sansom, O. J., Barry, S. T. & Inman, G., 1 Feb 2019, In : Molecular Pharmacology. 95, 2, p. 222-234 13 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
194 Downloads (Pure)
2017

Targeting BRAF-mutant tumours with TGFBR1 inhibitors

Spender, L. C. & Inman, G. J., 31 Jan 2017, In : Aging-US. 9, 1, p. 5-6 2 p.

Research output: Contribution to journalEditorial

Open Access
File
159 Downloads (Pure)
2016
Open Access
File
130 Downloads (Pure)

Inactivation of TGFβ receptors in stem cells drives cutaneous squamous cell carcinoma

Cammareri, P., Rose, A., Vincent, D. F., Wang, J., Nagano, A., Libertini, S., Ridgway, R. A., Athineos, D., Coates, P. J. ., McHugh, A., Pourreyron, C., Dayal, J., Larsson, J., Weidlich, S., Spender, L., Sapkota, G., Purdie, K. J., Proby, C., Harwood, C. A., Leigh, I. & 9 others, Clevers, H., Barker, N., Karlsson, S., Pritchard, C., Marais, R., Chelala, C., South, A., Sansom, O. J. & Inman, G., 25 Aug 2016, In : Nature Communications. 7, p. 1-7 7 p., 12493.

Research output: Contribution to journalArticle

Open Access
File
41 Citations (Scopus)
122 Downloads (Pure)

Mutational activation of BRAF confers sensitivity to transforming growth factor beta inhibitors in human cancer cells

Spender, L. C., Ferguson, G. J., Liu, S., Cui, C., Girotti, M. R., Sibbet, G., Higgs, E. B., Shuttleworth, M. K., Hamilton, T., Lorigan, P., Weller, M., Vincent, D. F., Sansom, O. J., Frame, M., Ten Dijke, P., Marais, R. & Inman, G. J., 13 Dec 2016, In : Oncotarget. 7, 50, p. 81995-82012 18 p.

Research output: Contribution to journalArticle

Open Access
File
9 Citations (Scopus)
230 Downloads (Pure)
2014

Developments in Burkitt's lymphoma: novel cooperations in oncogenic MYC signaling

Spender, L. C. & Inman, G. J., 2014, In : Cancer Management and Research. 6, p. 27-38 12 p.

Research output: Contribution to journalReview article

16 Citations (Scopus)
2012
34 Citations (Scopus)

Transforming Growth Factor-β directly induces PUMA during the rapid induction of apoptosis in Myc-driven B-cell lymphomas.

Spender, L. C., Carter, M. J., O'Brien, D. I., Clark, L. J., Yu, J., Michalak, E. M., Happo, L., Cragg, M. S. & Inman, G. J., 2012, In : Journal of Biological Chemistry.

Research output: Contribution to journalArticle

25 Citations (Scopus)
2011

Inhibition of germinal centre apoptotic programmes by epstein-barr virus

Spender, L. C. & Inman, G. J., 2011, In : Advances in Hematology. 2011, p. 829525

Research output: Contribution to journalArticle

8 Citations (Scopus)