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Author

  • Anthony Hope
2020
2019

Novel pharmacological actions of Trequinsin Hydrochloride improve human sperm cell motility and function

McBrinn, R. C., Fraser, J., Hope, A. G., Gray, D. W., Barratt, C. L. R., Martins da Silva, S. J. & Brown, S. G., Dec 2019, In : British Journal of Pharmacology. 176, 23, p. 4521-4536 16 p.

Research output: Contribution to journalArticle

Open Access
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43 Downloads (Pure)
2017

Drug discovery for male subfertility using high-throughput screening: a new approach to an unsolved problem

Martins Da Silva, S. J., Brown, S. G., Sutton, K., King, L. V., Ruso, H., Gray, D. W., Wyatt, P. G., Kelly, M. C., Barratt, C. L. R. & Hope, A. G., May 2017, In : Human Reproduction. 32, 5, p. 974-984 11 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
154 Downloads (Pure)

Identifying Inhibitors of Inflammation: A Novel High-Throughput MALDI-TOF Screening Assay for Salt-Inducible Kinases (SIKs)

Heap, R. E., Hope, A. G., Pearson, L-A., Reyskens, K. M. S. E., McElroy, S. P., Hastie, C. J., Porter, D. W., Arthur, J. S. C., Gray, D. W. & Trost, M., 1 Dec 2017, In : SLAS Discovery. 22, 10, p. 1193-1202 10 p.

Research output: Contribution to journalArticle

Open Access
File
20 Citations (Scopus)
283 Downloads (Pure)
2015

Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation

Kazlauskaite, A., Martínez-Torres, R. J., Wilkie, S., Kumar, A., Peltier, J., Gonzalez, A., Johnson, C., Zhang, J., Hope, A. G., Peggie, M., Trost, M., van Aalten, D. M., Alessi, D. R., Prescott, A. R., Knebel, A., Walden, H. & Muqit, M. MK., 1 Aug 2015, In : EMBO Reports. 16, 8, p. 939-954 16 p.

Research output: Contribution to journalArticle

Open Access
File
91 Citations (Scopus)
137 Downloads (Pure)
2013

Discovery of an Allosteric Inhibitor Binding Site in 3-Oxo-acyl-ACP Reductase from Pseudomonas aeruginosa

Cukier, C. D., Hope, A. G., Elamin, A. A., Moynie, L., Schnell, R., Schach, S., Kneuper, H., Singh, M., Naismith, J. H., Lindqvist, Y., Gray, D. W. & Schneider, G., 2013, In : ACS Chemical Biology. n/a, cb4005063.

Research output: Contribution to journalArticle

18 Citations (Scopus)