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• 2013

  Hookworm excretory/secretory products induce interleukin-4 (il-4)⁺ il-10⁺ cd4⁺ t cell responses and suppress pathology in a mouse model of colitis

  Ferreira, I., Smyth, D., Gaze, S., Aziz, A., Giacomin, P., Ruyssers, N., Artis, D., Laha, T., Navarro, S., Loukas, A. & McSorleya, H. J., 1 Jun 2013, In: Infection and Immunity. 81, 6, p. 2104-2111 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ancylostomatoidea
  • Colitis
  • Interleukin-4
  • Pathology
  • Interleukin-10
  67 Citations (Scopus)
• 2014

  Conjugative transfer of ICESde3396 between three β-hemolytic streptococcal species

  Smyth, D. J., Shera, J., Bauer, M. J., Cameron, A., McNeilly, C. L., Sriprakash, K. S. & McMillan, D. J., 12 Aug 2014, In: BMC Research Notes. 7, 1, 521.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Gene transfer
  • Streptococcus
  • Genes
  • Streptococcus agalactiae
  • Epithelial Cells
  3 Citations (Scopus)

• DrsG from Streptococcus dysgalactiae subsp. equisimilis inhibits the antimicrobial peptide LL-37

  Smyth, D., Cameron, A., Davies, M. R., McNeilly, C., Hafner, L., Sriprakash, K. S. & McMillan, D. J., 2014, In: Infection and Immunity. 82, 6, p. 2337-2344 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • antimicrobial peptide LL-37
  • Streptococcus
  • Proteins
  • Peptides
  • CAP18 lipopolysaccharide-binding protein
  10 Citations (Scopus)

• Helminths in the hygiene hypothesis: Sooner or later?

  Maizels, R. M., Mcsorley, H. J. & Smyth, D. J., Jul 2014, In: Clinical and Experimental Immunology. 177, 1, p. 38-46 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Hygiene Hypothesis
  • Helminths
  • Parasites
  • Immune System
  • Infection
  62 Citations (Scopus)

  41 Downloads (Pure)
• 2016

  Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites

  Gerbe, F., Sidot, E., Smyth, D. J., Ohmoto, M., Matsumoto, I., Dardalhon, V., Cesses, P., Garnier, L., Pouzolles, M., Brulin, B., Bruschi, M., Harcus, Y., Zimmermann, V. S., Taylor, N., Maizels, R. M. & Jay, P., 13 Jan 2016, In: Nature. 529, 7585, p. 226-230 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Mucosal Immunity
  • Helminths
  • Parasites
  • Epithelial Cells
  • Interleukins
  322 Citations (Scopus)

• Prostaglandin E₂ constrains systemic inflammation through an innate lymphoid cell-IL-22 axis

  Duffin, R., O'Connor, R. A., Crittenden, S., Forster, T., Yu, C., Zheng, X., Smyth, D., Robb, C. T., Rossi, F., Skouras, C., Tang, S., Richards, J., Pellicoro, A., Weller, R. B., Breyer, R. M., Mole, D. J., Iredale, J. P., Anderton, S. M., Narumiya, S., Maizels, R. M. & 4 others, Ghazal, P., Howie, S. E., Rossi, A. G. & Yao, C., 18 Mar 2016, In: Science. 351, 6279, p. 1333-1338 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • interleukin-22
  • Dinoprostone
  • Lymphocytes
  • Inflammation
  • Cardiovascular System
  85 Citations (Scopus)

• TGF-β in tolerance, development and regulation of immunity

  Johnston, C. J. C., Smyth, D. J., Dresser, D. W. & Maizels, R. M., Jan 2016, In: Cellular Immunology. 299, p. 14-22 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Parasites
  • Immunity
  • Developmental Biology
  • Helminths
  • Allergy and Immunology
  48 Citations (Scopus)
• 2017

  A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells

  Johnston, C. J. C., Smyth, D. J., Kodali, R. B., White, M. P. J., Harcus, Y., Filbey, K. J., Hewitson, J. P., Hinck, C. S., Ivens, A., Kemter, A. M., Kildemoes, A. O., Le Bihan, T., Soares, D. C., Anderton, S. M., Brenn, T., Wigmore, S. J., Woodcock, H. V., Chambers, R. C., Hinck, A. P., McSorley, H. J. & 1 others, Maizels, R. M., 23 Nov 2017, In: Nature Communications. 8, p. 1-13 13 p., 1741.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Nematospiroides dubius
  • T-cells
  • parasites
  • Parasites
  • Helminths
  54 Citations (Scopus)

  43 Downloads (Pure)

• HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33

  Osbourn, M., Soares, D. C., Vacca, F., Cohen, E. S., Scott, I. C., Gregory, W. F., Smyth, D. J., Toivakka, M., Kemter, A. M., le Bihan, T., Wear, M., Hoving, D., Filbey, K. J., Hewitson, J. P., Henderson, H., Gonzàlez-Cìscar, A., Errington, C., Vermeren, S., Astier, A. L., Wallace, W. A. & 4 others, Schwarze, J., Ivens, A. C., Maizels, R. M. & McSorley, H. J., 17 Oct 2017, In: Immunity. 47, 4, p. 739-751.e5 19 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Nematospiroides dubius
  • Alarmins
  • Interleukin-33
  • Helminths
  • Parasites
  53 Citations (Scopus)

  85 Downloads (Pure)
• 2019

  A Macrophage-Pericyte Axis Directs Tissue Restoration via Amphiregulin-Induced Transforming Growth Factor Beta Activation

  Minutti, C. M., Modak, R. V., Macdonald, F., Li, F., Smyth, D. J., Dorward, D. A., Blair, N., Husovsky, C., Muir, A., Giampazolias, E., Dobie, R., Maizels, R. M., Kendall, T. J., Griggs, D. W., Kopf, M., Henderson, N. C. & Zaiss, D. M., 19 Mar 2019, In: Immunity. 50, 3, p. 645-654.e6

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Amphiregulin
  • Pericytes
  • Transforming Growth Factor beta
  • Macrophages
  • Wounds and Injuries
  36 Citations (Scopus)

• Macrophage migration inhibitory factor (MIF) is essential for type 2 effector cell immunity to an intestinal helminth parasite

  Filbey, K. J., Varyani, F., Harcus, Y., Hewitson, J. P., Smyth, D. J., McSorley, H. J., Ivens, A., Nylén, S., Rottenberg, M., Löser, S. & Maizels, R. M., 24 Oct 2019, In: Frontiers in Immunology. 10, 2375.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Macrophage Migration-Inhibitory Factors
  • Helminths
  • Parasites
  • Immunity
  • indolepropanol phosphate
  3 Citations (Scopus)

  46 Downloads (Pure)