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  • Brian Lipworth

Proof of concept study to evaluate step-down therapy with inhaled corticosteroid alone or additive therapy on surrogate inflammatory markers in asthma

McKinlay, L., Williamson, P. A., Short, P. M., Fardon, T. & Lipworth, B. J., Jan 2011, In : British Journal of Clinical Pharmacology. 71, 1, p. 128-131 4 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Proof of concept evaluation of trough airway hyper-responsiveness following regular racemic or levosalbutamol in genotype-stratified steroid-treated persistent asthmatic patients

Anderson, W. J., Short, P. M., Williamson, P. A., Morrison, A. E., Palmer, C., Tavendale, R. & Lipworth, B. J., 1 Jan 2014, In : Clinical Science. 126, 1, p. 75-83 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Prescribing of β-adrenoceptor antagonists in asthma: an observational study

Morales, D. R., Guthrie, B., Lipworth, B. J., Donnan, P. T. & Jackson, C., Jun 2011, In : Thorax. 66, 6, p. 502-507 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Predicting severe outcomes in COVID-19

Lipworth, B., Chan, R. & Kuo, C., Sep 2020, In : The Journal of Allergy and Clinical Immunology: In Practice. 8, 8, p. 2582-2584 3 p.

Research output: Contribution to journalEditorial

Pneumonia Due to Inhaled Corticosteroids in COPD

Lipworth, B., Chan, R. & Kuo, C. R. W., Jun 2020, In : Chest. 157, 6, p. 1683-1684 2 p.

Research output: Contribution to journalLetter

Pharmacokinetic and pharmacodynamic comparison of hydrofluoroalkane and chlorofluorocarbon formulations of budesonide

Clearie, K. L., Williamson, P. A., Meldrum, K., Gillen, M., Carlsson, L-G., Carlholm, M., Ekelund, J. & Lipworth, B. J., Apr 2011, In : British Journal of Clinical Pharmacology. 71, 4, p. 504-513 10 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
1 Citation (Scopus)

Of mice and men-the curious tale of β blockers in asthma

Lipworth, B. & Jabbal, S., 2 Feb 2016, In : The Lancet Respiratory Medicine. 4, 2, p. 89-91 3 p.

Research output: Contribution to journalComment/debate

Open Access
File
163 Downloads (Pure)

Nasal nitric oxide as a measure of osteomeatal complex patency in nasal polyps

McKinlay, L., Vaidyanathan, S., Williamson, P. A. & Lipworth, B. J., Aug 2011, In : Annals of Allergy, Asthma & Immunology. 107, 2, p. 179-180 2 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Nasal AMP and histamine challenge within and outside the pollen season in patients with seasonal allergic rhinitis

Vaidyanathan, S., Williamson, P., Clearie, K., Morrison, A. & Lipworth, B., Jan 2011, In : Journal of Allergy and Clinical Immunology. 127, 1, p. 173-203.e3 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Making simple things complicated using anti-inflammatory reliever therapy

Lipworth, B., Kuo, C. R. & Chan, R., 30 Apr 2020, In : European Respiratory Journal. 55, 4, 2000267.

Research output: Contribution to journalArticle

Leukotriene antagonists in asthma

Lipworth, B. & Jackson, C., 21 Jul 2011, In : New England Journal of Medicine. 365, 3, p. 272-273 2 p.

Research output: Contribution to journalLetter

Left Ventricular Hypertrophy in COPD Without Hypoxemia: The Elephant in the Room?

Anderson, W. J., Lipworth, B. J., Rekhraj, S., Struthers, A. D. & George, J., Jan 2013, In : Chest. 143, 1, p. 91-97 7 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

LATE-BREAKING ABSTRACT: Real life impact of long acting beta-2-agonist withdrawal in controlled step 3 asthma patients

Jabbal, S., Manoharan, A., Anderson, W. & Lipworth, B., 8 Nov 2016, In : European Respiratory Journal. 48, Suppl60

Research output: Contribution to journalMeeting abstract

It is important to distinguish between HFrEF and HFpEF when interpreting these data

Lipworth, B., Skinner, D., Devereux, G., Thomas, V., Ling Zhi Jie, J., Martin, J., Carter, V. & Price, D. B., 1 Dec 2016, In : Heart (British Cardiac Society). 102, 23, 1 p., 1934.

Research output: Contribution to journalComment/debate

4 Citations (Scopus)

Is Gly16Arg β2 Receptor Polymorphism Related to Impulse Oscillometry in a Real-Life Asthma Clinic Setting?

Jabbal, S., Manoharan, A., Lipworth, J., Anderson, W., Short, P. & Lipworth, B., Apr 2016, In : Lung. 194, 2, p. 267-271 5 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
132 Downloads (Pure)

Is a positive nasal lysine-aspirin challenge test associated with a more severe phenotype of chronic rhinosinusitis and asthma?

Vaidyanathan, S., Williamson, P. A. & Lipworth, B. J., 2012, In : American Journal of Rhinology & Allergy. 26, 3, p. E89-E93 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Inhaled triple therapy in chronic obstructive pulmonary disease

Lipworth, B., Kuo, C. R. W. & Jabbal, S., 29 Sep 2018, In : The Lancet. 392, 10153, p. 1112-1113 2 p.

Research output: Contribution to journalLetter

Inhaled treatment for chronic obstructive pulmonary disease: what’s new and how does it fit?

Currie, G. P. & Lipworth, B. J., Aug 2016, In : QJM : an International Journal of Medicine. 109, 8, p. 505-512 8 p.

Research output: Contribution to journalReview article

6 Citations (Scopus)

Inhaled Corticosteroids and COVID-19

Lipworth, B., Kuo, C. R., Lipworth, S. & Chan, R., 15 Jul 2020, In : American Journal of Respiratory and Critical Care Medicine. 202, 6, p. 899-900 2 p.

Research output: Contribution to journalLetter

Open Access
File
27 Citations (Scopus)
11 Downloads (Pure)

Inhaled corticosteroid dose response using domiciliary exhaled nitric oxide in persistent asthma: the FENOtype trial

Anderson, W. J., Short, P., Williamson, P. A. & Lipworth, B. J., Dec 2012, In : Chest. 142, 6, p. 1553-61 9 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Inhaled corticosteroid dose-response on blood eosinophils in asthma

Lipworth, B., Jabbal, S., Manoharan, A., Anderson, W. & Short, P., Jan 2016, In : The Lancet Respiratory Medicine. 4, 1, p. e1

Research output: Contribution to journalLetter

Open Access
File
2 Citations (Scopus)
170 Downloads (Pure)

Inhaled and Systemic Corticosteroid Response in Severe Asthma Assessed by Alveolar Nitric Oxide: a randomised crossover pilot study of add-on therapy

Williamson, P. A., Short, P. M., Vaidyanathan, S. & Lipworth, B. J., Jan 2013, In : British Journal of Clinical Pharmacology. 75, 1, p. 93-102 10 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Inhaled and systemic corticosteroid response in moderate-to-severe asthma assessed by extended exhaled nitric oxide and lung function

Williamson, P. A., Short, P. M. & Lipworth, B. J., Dec 2011, In : Thorax. 66, Supplement 4, p. A7-A8 2 p., S9.

Research output: Contribution to journalBook/Film/Article review

Influence of β2-adrenoceptor 16 genotype on propranolol-induced bronchoconstriction in patients with persistent asthma

Anderson, W. J., Short, P. M., Manoharan, A., Lipworth, J. L. R. & Lipworth, B. J., 2014, In : Annals of Allergy, Asthma & Immunology. 112, 5, p. 475-476 2 p.

Research output: Contribution to journalLetter

4 Citations (Scopus)

Influence of β2-adrenergic receptor polymorphism on methacholine hyperresponsiveness in asthmatic patients

Manoharan, A., Anderson, W. J. & Lipworth, B. J., Mar 2013, In : Annals of Allergy, Asthma & Immunology. 110, 3, p. 161-164 4 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Improvements with sublingual house dust mite immunotherapy in allergic rhinitis

Lipworth, B., Aug 2016, In : Journal of Allergy and Clinical Immunology. 138, 2, p. 634-635 2 p.

Research output: Contribution to journalLetter

Open Access
File
1 Citation (Scopus)
172 Downloads (Pure)

Improved lung function and patient-reported outcomes with co-suspension delivery technology glycopyrrolate/formoterol fumarate metered dose inhaler in COPD: a randomized Phase III study conducted in Asia, Europe, and the USA

Lipworth, B. J., Collier, D. J., Gon, Y., Zhong, N., Nishi, K., Chen, R., Arora, S., Maes, A., Siddiqui, S., Reisner, C. & Martin, U. J., 26 Sep 2018, In : International Journal of Chronic Obstructive Pulmonary Disease. 13, p. 2969-2984 16 p.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
133 Downloads (Pure)

Implication of alternative minimal clinically important difference threshold estimation on technology assessment

Brixner, D., Meltzer, E. O., Marland, K., Carroll, C. A., Munzel, U. & Lipworth, B., 6 Dec 2016, In : International Journal of Technology Assessment in Health Care. 32, 6, p. 371-375 5 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
135 Downloads (Pure)

Impact of long-acting bronchodilators and exposure to inhaled corticosteroids on mortality in COPD: a real-life retrospective cohort study

Manoharan, A., Short, P. M., Anderson, W. J. & Lipworth, B. J., Oct 2014, In : Lung. 192, 5, p. 649-652 4 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Guidelines to establish relative potency are not in touch with reality

Lipworth, B. & Clearie, K., Nov 2011, In : British Journal of Clinical Pharmacology. 72, 5, p. 834-835 2 p.

Research output: Contribution to journalLetter

1 Citation (Scopus)

Glycopyrrolate/formoterol fumarate metered dose inhaler improves lung function versus monotherapies in GOLD category a patients with COPD: Pooled data from the phase III PINNACLE studies

Martinez, F. J., Rabe, K. F., Lipworth, B. J., Arora, S., Jenkins, M., Martin, U. J. & Reisner, C., 2020, In : International Journal of COPD. 15, p. 99-106 8 p.

Research output: Contribution to journalArticle

Open Access
File
41 Downloads (Pure)

Glycopyrrolate/formoterol fumarate metered dose inhaler for maintenance-naïve patients with chronic obstructive pulmonary disease: a post-hoc analysis of the randomized PINNACLE trials

Zheng, J., Xu, J-F., Jenkins, M., Assam, P. N., Wang, L. & Lipworth, B. J., 12 Mar 2020, In : Respiratory Research. 21, 1, p. 1-10 10 p., 69.

Research output: Contribution to journalArticle

Open Access
File
32 Downloads (Pure)

From mouse to man: predicting biased effects of beta-blockers in asthma

Lipworth, B. J., Anderson, W. J. & Short, P. M., Jan 2016, In : British Journal of Pharmacology. 173, 1, p. 248-249 2 p.

Research output: Contribution to journalLetter

Open Access
File
2 Citations (Scopus)
166 Downloads (Pure)

Fluticasone/Salmeterol Combination Confers Benefits in People With Asthma Who Smoke

Clearie, K. L., McKinlay, L., Williamson, P. A. & Lipworth, B. J., Feb 2012, In : Chest. 141, 2, p. 330-338 9 p.

Research output: Contribution to journalArticle

34 Citations (Scopus)

Explaining differential effects of tiotropium on mortality in COPD

Lipworth, B. J. & Short, P., 2013, In : Thorax. 68, 6, p. 589-590 2 p.

Research output: Contribution to journalLetter

3 Citations (Scopus)

Emerging role of long acting muscarinic antagonists for asthma

Lipworth, B. J., Jan 2014, In : British Journal of Clinical Pharmacology. 77, 1, p. 55-62 8 p.

Research output: Contribution to journalReview article

25 Citations (Scopus)

Emerging pharmacotherapy for COVID-19

Lipworth, B., Kuo, C. R. & Chan, R., Jun 2020, In : Journal of the Royal College of Physicians of Edinburgh. 50, 2, p. 133-137 5 p.

Research output: Contribution to journalReview article

Open Access
File
16 Citations (Scopus)
78 Downloads (Pure)

Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19

Herold, T., Jurinovic, V., Arnreich, C., Lipworth, B. J., Hellmuth, J. C., von Bergwelt-Baildon, M., Klein, M. & Weinberger, T., Jul 2020, In : Journal of Allergy and Clinical Immunology. 146, 1, p. 128-136.e4 13 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)

Effects of the inverse alpha-agonist doxazosin in allergic rhinitis

Manoharan, A., Morrison, A. E. & Lipworth, B. J., May 2016, In : Clinical and Experimental Allergy. 46, 5, p. 696-704 9 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
170 Downloads (Pure)

Effects of intravenous and oral β-blockade in persistent asthmatics controlled on inhaled corticosteroids

Short, P. M., Anderson, W. J., Williamson, P. A. & Lipworth, B. J., Feb 2014, In : Heart (British Cardiac Society). 100, 3, p. 219-223 5 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Effects of intranasal salmeterol and fluticasone given alone and in combination in persistent allergic rhinitis

Lipworth, B. J., Short, P., Burns, P. & Nair, A., Jan 2012, In : Annals of Allergy, Asthma & Immunology. 108, 1, p. 54-59 6 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Effects of hydrocortisone on acute β-adrenoceptor blocker and histamine induced bronchoconstriction

Short, P. M., Williamson, P. A. & Lipworth, B. J., May 2012, In : British Journal of Clinical Pharmacology. 73, 5, p. 717-726 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)