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Author

  • Danielle Smyth
2019

A Macrophage-Pericyte Axis Directs Tissue Restoration via Amphiregulin-Induced Transforming Growth Factor Beta Activation

Minutti, C. M., Modak, R. V., Macdonald, F., Li, F., Smyth, D. J., Dorward, D. A., Blair, N., Husovsky, C., Muir, A., Giampazolias, E., Dobie, R., Maizels, R. M., Kendall, T. J., Griggs, D. W., Kopf, M., Henderson, N. C. & Zaiss, D. M., 19 Mar 2019, In : Immunity. 50, 3, p. 645-654.e6

Research output: Contribution to journalArticle

Open Access
29 Citations (Scopus)

Macrophage migration inhibitory factor (MIF) is essential for type 2 effector cell immunity to an intestinal helminth parasite

Filbey, K. J., Varyani, F., Harcus, Y., Hewitson, J. P., Smyth, D. J., McSorley, H. J., Ivens, A., Nylén, S., Rottenberg, M., Löser, S. & Maizels, R. M., 24 Oct 2019, In : Frontiers in Immunology. 10, 2375.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
35 Downloads (Pure)
2018

A context-dependent role for αv integrins in regulatory T cell accumulation at sites of inflammation

Mair, I., Zandee, S. E. J., Toor, I. S., Saul, L., McPherson, R. C., Leech, M. D., Smyth, D. J., O'Connor, R. A., Henderson, N. C. & Anderton, S. M., 26 Feb 2018, In : Frontiers in Immunology. 9, FEB, 264.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
12 Downloads (Pure)

TGF-β mimic proteins form an extended gene family in the murine parasite Heligmosomoides polygyrus

Smyth, D. J., Harcus, Y., White, M. P. J., Gregory, W. F., Nahler, J., Stephens, I., Toke-Bjolgerud, E., Hewitson, J. P., Ivens, A., McSorley, H. J. & Maizels, R. M., Apr 2018, In : International Journal for Parasitology. 48, 5, p. 379-385 7 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
31 Downloads (Pure)
2017

A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells

Johnston, C. J. C., Smyth, D. J., Kodali, R. B., White, M. P. J., Harcus, Y., Filbey, K. J., Hewitson, J. P., Hinck, C. S., Ivens, A., Kemter, A. M., Kildemoes, A. O., Le Bihan, T., Soares, D. C., Anderton, S. M., Brenn, T., Wigmore, S. J., Woodcock, H. V., Chambers, R. C., Hinck, A. P., McSorley, H. J. & 1 others, Maizels, R. M., 23 Nov 2017, In : Nature Communications. 8, p. 1-13 13 p., 1741.

Research output: Contribution to journalArticle

Open Access
File
48 Citations (Scopus)
38 Downloads (Pure)

HpARI Protein Secreted by a Helminth Parasite Suppresses Interleukin-33

Osbourn, M., Soares, D. C., Vacca, F., Cohen, E. S., Scott, I. C., Gregory, W. F., Smyth, D. J., Toivakka, M., Kemter, A. M., le Bihan, T., Wear, M., Hoving, D., Filbey, K. J., Hewitson, J. P., Henderson, H., Gonzàlez-Cìscar, A., Errington, C., Vermeren, S., Astier, A. L., Wallace, W. A. & 4 others, Schwarze, J., Ivens, A. C., Maizels, R. M. & McSorley, H. J., 17 Oct 2017, In : Immunity. 47, 4, p. 739-751.e5 19 p.

Research output: Contribution to journalArticle

Open Access
File
47 Citations (Scopus)
39 Downloads (Pure)
2016

Intestinal epithelial tuft cells initiate type 2 mucosal immunity to helminth parasites

Gerbe, F., Sidot, E., Smyth, D. J., Ohmoto, M., Matsumoto, I., Dardalhon, V., Cesses, P., Garnier, L., Pouzolles, M., Brulin, B., Bruschi, M., Harcus, Y., Zimmermann, V. S., Taylor, N., Maizels, R. M. & Jay, P., 13 Jan 2016, In : Nature. 529, 7585, p. 226-230 5 p.

Research output: Contribution to journalArticle

297 Citations (Scopus)

Prostaglandin E2 constrains systemic inflammation through an innate lymphoid cell-IL-22 axis

Duffin, R., O'Connor, R. A., Crittenden, S., Forster, T., Yu, C., Zheng, X., Smyth, D., Robb, C. T., Rossi, F., Skouras, C., Tang, S., Richards, J., Pellicoro, A., Weller, R. B., Breyer, R. M., Mole, D. J., Iredale, J. P., Anderton, S. M., Narumiya, S., Maizels, R. M. & 4 others, Ghazal, P., Howie, S. E., Rossi, A. G. & Yao, C., 18 Mar 2016, In : Science. 351, 6279, p. 1333-1338 6 p.

Research output: Contribution to journalArticle

Open Access
77 Citations (Scopus)

TGF-β in tolerance, development and regulation of immunity

Johnston, C. J. C., Smyth, D. J., Dresser, D. W. & Maizels, R. M., Jan 2016, In : Cellular Immunology. 299, p. 14-22 9 p.

Research output: Contribution to journalArticle

Open Access
44 Citations (Scopus)
2015

Cultivation of Heligmosomoides polygyrus: An immunomodulatory nematode parasite and its secreted products

Johnston, C. J. C., Robertson, E., Harcus, Y., Grainger, J. R., Coakley, G., Smyth, D. J., McSorley, H. J. & Maizels, R., 6 Apr 2015, In : Journal of Visualized Experiments. 98, p. 1-10 10 p., e52412.

Research output: Contribution to journalArticle

Open Access
File
32 Citations (Scopus)
43 Downloads (Pure)
2013

Hookworm excretory/secretory products induce interleukin-4 (il-4)+ il-10+ cd4+ t cell responses and suppress pathology in a mouse model of colitis

Ferreira, I., Smyth, D., Gaze, S., Aziz, A., Giacomin, P., Ruyssers, N., Artis, D., Laha, T., Navarro, S., Loukas, A. & McSorleya, H. J., 1 Jun 2013, In : Infection and Immunity. 81, 6, p. 2104-2111 8 p.

Research output: Contribution to journalArticle

Open Access
64 Citations (Scopus)