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• A moving interface finite element formulation to predict dynamic edge debonding in FRP-strengthened concrete beams in service conditions

  Funari, M. F., Spadea, S., Fabbrocino, F. & Luciano, R., Jun 2020, In: Fibers. 8, 6, p. 1-9 9 p., 42.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Debonding
  • Polymers
  • Fibers
  • Concretes
  • Crack initiation
  5 Citations (Scopus)

  213 Downloads (Pure)

• AMP-activated protein kinase: also regulated by ADP?

  Hardie, D. G., Carling, D. & Gamblin, S. J., Sep 2011, In: Trends in Biochemical Sciences. 36, 9, p. 470-477 8 p.

  Research output: Contribution to journal › Review article › peer-review
  123 Citations (Scopus)

• AMP-activated protein kinase: a cellular energy sensor with a key role in metabolic disorders and in cancer

  Hardie, D. G., Feb 2011, In: Biochemical Society Transactions. 39, p. 1-13 13 p.

  Research output: Contribution to journal › Article › peer-review
  124 Citations (Scopus)

• AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function

  Hardie, D. G., 15 Sep 2011, In: Genes & Development. 25, 18, p. 1895-1908 14 p.

  Research output: Contribution to journal › Review article › peer-review
  968 Citations (Scopus)

• AMP-Activated Protein Kinase: A Target for Drugs both Ancient and Modern

  Hardie, D. G., Ross, F. A. & Hawley, S. A., 26 Oct 2012, In: Chemistry & Biology. 19, 10, p. 1222-36 15 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Cyclic AMP-Dependent Protein Kinases
  • Metformin
  • Adenosine Triphosphate
  • Medical problems
  252 Citations (Scopus)

  171 Downloads (Pure)

• AMP-Activated Protein Kinase: Friend or Foe in Cancer

  Vara-ciruelos, D., Dandapani, M. & Hardie, D. G., 4 Mar 2020, In: Annual Review of Cancer Biology. 4, p. 1-16 16 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Neoplasms
  • T-Cell Lymphoma
  • Carcinogenesis
  • Protein Kinase Inhibitors
  3 Citations (Scopus)

  43 Downloads (Pure)

• AMP-Activated Protein Kinase: Do We Need Activators or Inhibitors to Treat or Prevent Cancer?

  Russell, F. M. & Hardie, D. G., 27 Dec 2020, In: International Journal of Molecular Sciences. 22, 1, 30 p., 186.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • adenosine monophosphate
  • AMP-Activated Protein Kinases
  • inhibitors
  • cancer
  • Proteins
  57 Downloads (Pure)

• AMP-activated protein kinase, a tumor suppressor that opposes the metabolic changes in cancer cells

  Hardie, D. G., Jun 2011, In: FEBS Journal. 278, s1, p. 41-42 2 p.

  Research output: Contribution to journal › Book/Film/Article review › peer-review

• AMP-activated protein kinase (AMPK)α2 plays a role in determining the cellular fate of glucose in insulin-resistant mouse skeletal muscle

  Lee-Young, R. S., Bonner, J. S., Mayes, W. H., Iwueke, I., Barrick, B. A., Hasenour, C. M., Kang, L. & Wasserman, D. H., Mar 2013, In: Diabetologia. 56, 3, p. 608-617 10 p.

  Research output: Contribution to journal › Article › peer-review

  • AMP-Activated Protein Kinases
  • Skeletal Muscle
  • Insulin
  • Nitric Oxide Synthase Type II
  • Lipids
  18 Citations (Scopus)

• AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study

  Boyle, J. G., Logan, P. J., Jones, G. C., Small, M., Sattar, N., Connell, J. M. C., Cleland, S. J. & Salt, I. P., 2011, In: Diabetologia. 54, 7, p. 1799-1809 11 p.

  Research output: Contribution to journal › Article › peer-review
  54 Citations (Scopus)

• AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase

  Bultot, L., Guigas, B., Von Wilamowitz-Moellendorff, A., Maisin, L., Vertommen, D., Hussain, N., Beullens, M., Guinovart, J. J., Foretz, M., Viollet, B., Sakamoto, K., Hue, L. & Rider, M. H., 1 Apr 2012, In: Biochemical Journal. 443, p. 193-203 11 p.

  Research output: Contribution to journal › Article › peer-review
  59 Citations (Scopus)

• AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation

  Gowans, G. J., Hawley, S. A., Ross, F. A. & Hardie, D. G., 1 Oct 2013, In: Cell Metabolism. 18, 4, p. 556-566 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Adenosine Monophosphate
  • Phosphorylation
  • Adenosine Diphosphate
  • Adenosine Triphosphate
  275 Citations (Scopus)

  167 Downloads (Pure)

• AMPK: opposing the metabolic changes in both tumour cells and inflammatory cells?

  Dandapani, M. & Hardie, D. G., Apr 2013, In: Biochemical Society Transactions. 41, 2, p. 687-693 7 p.

  Research output: Contribution to journal › Article › peer-review
  34 Citations (Scopus)

• AMPK: a target for drugs and natural products with effects on both diabetes and cancer

  Hardie, D. G., Jul 2013, In: Diabetes. 62, 7, p. 2164-2172 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Biological Products
  • Metformin
  • Pharmaceutical Preparations
  • Salicylates
  264 Citations (Scopus)

  143 Downloads (Pure)

• AMPK: mediating the metabolic effects of salicylate-based drugs?

  Steinberg, G. R., Dandapani, M. & Hardie, D. G., Oct 2013, In: Trends in Endocrinology and Metabolism. 24, 10, p. 481-487 7 p.

  Research output: Contribution to journal › Review article › peer-review

  • Salicylates
  • AMP-Activated Protein Kinases
  • salicylsalicylic acid
  • Pharmaceutical Preparations
  • Aspirin
  50 Citations (Scopus)

• AMPK: a nutrient and energy sensor that maintains energy homeostasis

  Hardie, D. G., Ross, F. A. & Hawley, S. A., 1 Apr 2012, In: Nature Reviews Molecular Cell Biology. 13, 4, p. 251-262 12 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Nutrients
  • Adenosine Triphosphate
  • Homeostasis
  • Biosynthetic Pathways
  2210 Citations (Scopus)

  243 Downloads (Pure)

• AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1-Parkin independent manner

  Seabright, A. P., Fine, N. H. F., Barlow, J. P., Lord, S. O., Musa, I., Gray, A., Bryant, J. A., Banzhaf, M., Lavery, G. G., Hardie, D. G., Hodson, D. J., Philp, A. & Lai, Y-C., 4 May 2020, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34, 5, p. 6284-6301 18 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Mitochondrial Degradation
  • Mitochondrial Dynamics
  • Adenosine Monophosphate
  • Protein Kinases
  • Chemical activation
  4 Citations (Scopus)

  81 Downloads (Pure)

• AMPK activators inhibit the proliferation of human melanomas bearing the activated MAPK pathway

  Petti, C., Vegetti, C., Molla, A., Bersani, I., Cleris, L., Mustard, K. J., Formelli, F., Hardie, G. D., Sensi, M. & Anichini, A., 2012, In: Melanoma Research. 22, 5, p. 341-350 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Melanoma
  • acadesine
  • 4-aminoimidazole
  • Phenformin
  • Mitogen-Activated Protein Kinase Kinases
  34 Citations (Scopus)

• AMPK and autophagy get connected

  Hardie, D. G., 16 Feb 2011, In: EMBO Journal. 30, 4, p. 634-635 2 p.

  Research output: Contribution to journal › Editorial › peer-review
  123 Citations (Scopus)

• AMPK and the Need to Breathe and Feed: What's the Matter with Oxygen?

  Evans, A. M. & Hardie, D. G., 15 May 2020, In: International Journal of Molecular Sciences. 21, 10, p. 1-28 28 p., 3518.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • adenosine monophosphate
  • AMP-Activated Protein Kinases
  • Oxygen supply
  • Proteins
  • Oxygen
  29 Downloads (Pure)

• AMPK and TOR: the Yin and Yang of cellular nutrient sensing and growth control

  González, A., Hall, M. N., Lin, S-C. & Hardie, G., 3 Mar 2020, In: Cell Metabolism. 31, 3, p. 472-492 21 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Yin-Yang
  • AMP-Activated Protein Kinases
  • Sirolimus
  • Nutrients
  • Growth
  29 Citations (Scopus)

• AMPK as a direct sensor of long-chain fatty acyl–CoA esters

  Hardie, D. G., 27 Jul 2020, In: Nature Metabolism. 2, 9, p. 799-800 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Esters
  • Starvation
  • Ligands
  • Glucose
  4 Citations (Scopus)

  11 Downloads (Pure)

• AMPK modulates glucose-sensing in insulin-secreting cells by altered phosphotransfer to KATP channels

  Beall, C., Watterson, K. R., McCrimmon, R. J. & Ashford, M. L. J., Jun 2013, In: Journal of Bioenergetics and Biomembranes. 45, 3, p. 229-241 13 p.

  Research output: Contribution to journal › Article › peer-review

  • KATP Channels
  • AMP-Activated Protein Kinases
  • Insulin-Secreting Cells
  • Glucose
  • Adenylate Kinase
  14 Citations (Scopus)

• AMPK promotes p53 acetylation via phosphorylation and inactivation of SIRT1 in liver cancer cells

  Lee, C-W., Wong, L. L-Y., Tse, E. Y-T., Liu, H-F., Leong, V. Y-L., Lee, J. M-F., Hardie, D. G., Ng, I. O-L. & Ching, Y-P., 2012, In: Cancer Research. 72, 17, p. 4394-4404 11 p.

  Research output: Contribution to journal › Article › peer-review

  • AMP-Activated Protein Kinases
  • Acetylation
  • Liver Neoplasms
  • Phosphorylation
  • Hepatocellular Carcinoma
  132 Citations (Scopus)

• AMPKα1: a glucose sensor that controls CD8 T-cell memory

  Rolf, J., Zarrouk, M., Finlay, D. K., Foretz, M., Viollet, B. & Cantrell, D. A., Apr 2013, In: European Journal of Immunology. 43, 4, p. 889-896 8 p.

  Research output: Contribution to journal › Article › peer-review
  138 Citations (Scopus)

• A MRI investigation of electroconvulsive therapy (ECT) for the treatment of depression

  Perrin, J. S., Bennett, D. M., Currie, J., Steele, J. D. & Reid, I. C., Aug 2011, In: Journal of Psychopharmacology. 25, 8, p. A54-A54 1 p.

  Research output: Contribution to journal › Book/Film/Article review › peer-review

• A multi-centre, prospective epidemiological surveillance study considering ophthalmic complications of functional endoscopic sinus surgery

  Burgess, S., Foulds, J., White, P., Foot, B. & Macewen, C., Mar 2020, In: Journal of Laryngology and Otology. 134, 3, p. 228-232 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Epidemiologic Studies
  • Eye
  • Nasolacrimal Duct
  • Muscles
  • Consultants
  1 Citation (Scopus)

  47 Downloads (Pure)

• A multicentre review of bakery and dental series allergens tested for cheilitis in the UK

  Fatah, S., Horne, H. L., Wilkinson, S. M., Gawkrodger, D. J., English, J. S. C., Green, C. M., Ormerod, A. D., Chowdhury, M. M. U., Cooper, S. M., Stone, N. M., King, C. M. & Johnston, G. A., Jul 2013, In: British Journal of Dermatology. 169, Suppl. 1, p. 132 1 p., CD09.

  Research output: Contribution to journal › Meeting abstract › peer-review

• A Multi-disciplinary Approach to the Archaeological Investigation of a Bedrock-Dominated Shallow-Marine Landscape: An example from the Bay of Firth, Orkney, UK

  Bates, M. R., Nayling, N., Bates, R., Dawson, S., Huws, D. & Wickham-Jones, C., Mar 2013, In: International Journal of Nautical Archaeology. 42, 1, p. 24-43 20 p.

  Research output: Contribution to journal › Article › peer-review

  • Orkney
  • Archaeological Investigation
  • archaeology
  • bedrock
  • Coastal Geomorphology
  22 Citations (Scopus)

• A Multifunctional Protease Inhibitor To Regulate Endolysosomal Function

  van Kasteren, S. I., Berlin, I., Colbert, J. D., Keane, D., Ovaa, H. & Watts, C., Nov 2011, In: ACS Chemical Biology. 6, 11, p. 1198-1204 7 p.

  Research output: Contribution to journal › Article › peer-review
  16 Citations (Scopus)

• A multigenic model to predict risk of ischemic stroke in subjects with type 2 diabetes

  Pola, R., Kimber, C. H., Giarretta, I., Doney, A., Morris, A. M., Gaetani, E. & Palmer, C. N., Jun 2011, In: Atherosclerosis. Supplements. 12, 1, p. 127-127 1 p.

  Research output: Contribution to journal › Article › peer-review

• A multiorganism pipeline for antiseizure drug discovery: Identification of chlorothymol as a novel γ-aminobutyric acidergic anticonvulsant

  Jones, A., Barker-Haliski, M., Ilie, A. S., Herd, M. B., Baxendale, S., Holdsworth, C. J., Ashton, J. P., Placzek, M., Jayasekera, B. A. P., Cowie, C. J. A., Lambert, J. J., Trevelyan, A. J., White, H. S., Marson, A. G., Cunliffe, V. T., Sills, G. J. & Morgan, A., Oct 2020, In: Epilepsia. 61, 10, p. 2106-2118 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Drug Discovery
  • Anticonvulsants
  • Seizures
  • Epilepsy
  • Zebrafish
  24 Downloads (Pure)

• A multiprotein binding interface in an intrinsically disordered region of the tumor suppressor protein interferon regulatory factor-1

  Narayan, V., Halada, P., Hernychová, L., Chong, Y. P., Žáková, J., Hupp, T. R., Vojtesek, B. & Ball, K. L., 22 Apr 2011, In: Journal of Biological Chemistry. 286, 16, p. 14291-14303 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Interferon Regulatory Factor-1
  • Tumor Suppressor Proteins
  • Affinity chromatography
  • Peptide Aptamers
  • Carrier Proteins
  22 Citations (Scopus)

• A multi-repeat adhesin of the phytopathogen, Pectobacterium atrosepticum, is secreted by a Type I pathway and is subject to complex regulation involving a non-canonical diguanylate cyclase

  Perez-Mendoza, D., Coulthurst, S. J., Humphris, S., Campbell, E., Welch, M., Toth, I. K. & Salmond, G. P. C., Nov 2011, In: Molecular Microbiology. 82, 3, p. 719-733 15 p.

  Research output: Contribution to journal › Article › peer-review
  43 Citations (Scopus)

• A multiscale approach to curvature modulated sorting in biological membranes

  Mercker, M., Ptashnyk, M., Kuhnle, J., Hartmann, D., Weiss, M. & Jager, W., May 2012, In: Journal of Theoretical Biology. 301, 5, p. 67-82 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Biological membranes
  • Sorting
  • sorting
  • Membrane
  • Curvature
  18 Citations (Scopus)

• A multiscale moving boundary model arising in cancer invasion

  Trucu, D., Lin, P., Chaplain, M. A. J. & Wang, Y., 2013, In: Multiscale Modeling and Simulation: A SIAM Interdisciplinary Journal. 11, 1, p. 309-335 27 p.

  Research output: Contribution to journal › Article › peer-review

  • Invasion
  • Moving Boundary
  • Cancer
  • Cells
  • cancer
  22 Citations (Scopus)

• Amyloid β fibril disruption by oleuropein aglycone: long-time molecular dynamics simulation to gain insight into the mechanism of action of this polyphenol from extra virgin olive oil

  Brogi, S., Sirous, H., Calderone, V. & Chemi, G., 23 Sep 2020, In: Food & Function. 11, 9, p. 8122-8132 11 p.

  Research output: Contribution to journal › Article › peer-review

  • oleuropein aglycone
  • oleuropein
  • extra-virgin olive oil
  • molecular dynamics
  • Olive Oil

• An accuracy assessment of forensic computerized facial reconstruction employing cone-beam computed tomography from live subjects

  Lee, W-J., Wilkinson, C. M. & Hwang, H-S., Mar 2012, In: Journal of Forensic Sciences. 57, 2, p. 318-327 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Cone-Beam Computed Tomography
  • Skull
  • Software
  53 Citations (Scopus)

• An adaptive IEEE 802.15.4 data transmission scheme for smart grid applications

  Che, Z., He, J., Tang, Z., Zhou, Y. & Chen, K., 23 Dec 2011, U- and E-Service, Science and Technology - International Conference, UNESST 2011, Held as Part of the Future Generation Information Technology Conf., FGIT 2011, in Conjunction with GDC 2011, Proc.. Berlin, p. 93-99 7 p. (Communications in Computer and Information Science; vol. 264 CCIS).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • IEEE 802.15.4
  • Smart Grid
  • Data Transmission
  • Data communication systems
  • Bandwidth
  1 Citation (Scopus)

• An adaptive IEEE 802.15.4 MAC layer transmission scheme for applications with heterogeneous traffic

  Zhou, Y., He, J., Chen, K., Tang, Z. & Li, Y., Dec 2013, In: Information: An Interdisciplinary Journal in English, Japanese and Chinese . 16, 12 A, p. 8451-8456 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Access control
  • Bandwidth
  • Carrier sense multiple access
  • Data communication systems
  • Energy efficiency

• An adaptive information technology for the operative diagnostics of the tropical cyclones: solar-terrestrial coupling mechanisms

  Krapivin, V. F., Soldatov, V. Y., Varotsos, C. A. & Cracknell, A. P., 2012, In: Journal of Atmospheric and Solar-Terrestrial Physics. 89, p. 83-89 7 p.

  Research output: Contribution to journal › Article › peer-review

  • cyclones
  • information technology
  • tropical cyclone
  • sequential analysis
  • oceans
  17 Citations (Scopus)

• Analgesic drugs

  Colvin, L., Sep 2013, Smith and Aitkenhead's Textbook of Anaesthesia. Aitkenhead, A., Thompson, J., Rowbotham, D. & Moppett, I. (eds.). 6 ed. Churchill Livingstone Elsevier, p. 69-86 18 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

• Analgesic tone conferred by constitutively active mu opioid receptors in mice lacking beta-arrestin 2

  Lam, H., Maga, M., Pradhan, A., Evans, C. J., Maidment, N. T., Hales, T. G. & Walwyn, W., 12 Apr 2011, In: Molecular Pain. 7, p. - 10 p., 24.

  Research output: Contribution to journal › Article › peer-review
  19 Citations (Scopus)

• Analogy and arithmetic: an HDTP-based model of the calculation circular staircase

  Besold, T., Schmidt, M. & Pease, A., 2013, Cooperative Minds: Social Interaction and Group Dynamics: Proceedings of the 35th Annual Conference of the Cognitive Science Society. Knauff, M., Pauen, M., Sebanz, N. & Wachsmuth, I. (eds.). Austin: Cognitive Science Society, p. 1893-1898 6 p.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

• Analyses of groundwater flow and plant evapotranspiration in a vegetated soil slope

  Leung, A. K. & Ng, C. W. W., Dec 2013, In: Canadian Geotechnical Journal. 50, 12, p. 1204-1218 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Evapotranspiration
  • Groundwater flow
  • groundwater flow
  • evapotranspiration
  • Soils
  44 Citations (Scopus)

• Analysing time-related properties of service-oriented systems

  Bocchi, L., Fiadeiro, J., Solanki, M., Gilmore, S., Abreu, J. & Vankayala, V., 1 Dec 2011, Handbook of Research on Service-Oriented Systems and Non-Functional Properties: Future Directions. IGI Global, p. 36-60 25 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Modeling languages
  • Algebra
  • Quality of service
  • Chemical analysis
  • Specifications

• Analysis and Approximation of Microstructure Models: preface to special issue

  Muntean, A., Ptashnyk, M. & Showalter, R. E., 1 Jun 2012, In: Applicable Analysis. 91, 6, p. 1053-1054 2 p.

  Research output: Contribution to journal › Special issue
  2 Citations (Scopus)

• Analysis and identification of spamming behaviors in Sina Weibo Microblog

  Lin, C., He, J., Zhou, Y., Yang, X., Chen, K. & Song, L., 2013, Proceedings of the 7th Workshop on Social Network Mining and Analysis, SNA-KDD 2013. New York: Association for Computing Machinery (ACM), 5

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  • Spamming
  • Marketing
  • Identification (control systems)
  • Classifiers
  27 Citations (Scopus)

• Analysis for Time Discrete Approximations of Blow-up Solutions of Semilinear Parabolic Equations

  Kyza, I. & Makridakis, C., 2011, In: SIAM Journal on Numerical Analysis. 49, 1, p. 405-426 22 p.

  Research output: Contribution to journal › Article › peer-review
  13 Citations (Scopus)

• Analysis of > 1000 single nucleotide polymorphisms in geographically matched samples of landrace and wild barley indicates secondary contact and chromosome-level differences in diversity around domestication genes

  Russell, J., Dawson, I. K., Flavell, A. J., Steffenson, B., Weltzien, E., Booth, A., Ceccarelli, S., Grando, S. & Waugh, R., 2011, In: New Phytologist. 191, 2, p. 564-578 15 p.

  Research output: Contribution to journal › Article › peer-review
  56 Citations (Scopus)