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  • Paul Appleton
2020

Measurement of eroded dentine tubule patency and roughness following novel dab-on or brushing abrasion

Olley, R. C., Mohsen, B. M., Alhaij, S. & Appleton, P. L., 5 May 2020, In : Journal of Dentistry. 103358.

Research output: Contribution to journalArticle

Novel Confocal-Laser-Scanning-Microscopy and conventional measures investigating eroded dentine following dentifrice dab-on and brushing abrasion

Olley, R. C., Alhaij, S., Mohsen, B. M., Appleton, P. L., Chadwick, R. G. & Ball, G., Mar 2020, In : Heliyon. 6, 3, p. 1-8 8 p., e03282.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
23 Downloads (Pure)
2019
Open Access
File
1 Citation (Scopus)
128 Downloads (Pure)
2018
Open Access
File
3 Citations (Scopus)
157 Downloads (Pure)
2017

Interkinetic nuclear migration and basal tethering facilitates post-mitotic daughter separation in intestinal organoids

Carroll, T. D., Langlands, A. J., Osborne, J. M., Newton, I. P., Appleton, P. L. & Nathke, I., 15 Nov 2017, In : Journal of Cell Science. 130, 22, p. 3862-3877 16 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
148 Downloads (Pure)

Optimal repetition rate and pulse duration studies for two photon imaging

Mirkhanov, S., Quarterman, A. H., Smyth, C. J. C. P., Praveen, B. B., Appleton, P., Thomson, C., Swift, S. & Wilcox, K. G., 28 Jan 2017, Multiphoton Microscopy in the Biomedical Sciences XVII. SPIE-International Society for Optical Engineering, Vol. 10069. 100692F

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

RPA-Mediated Recruitment of the E3 Ligase RFWD3 Is Vital for Interstrand Crosslink Repair and Human Health

Feeney, L., Munoz, I. M., Lachaud, C., Toth, R., Appleton, P. L., Schindler, D. & Rouse, J., 1 Jun 2017, In : Molecular Cell. 66, 5, p. 610-621.e4 16 p.

Research output: Contribution to journalArticle

Open Access
File
20 Citations (Scopus)
175 Downloads (Pure)

Second harmonic generation (SHG) imaging of cancer heterogeneity in ultrasound guided biopsies of prostate in men suspected with prostate cancer

Ling, Y., Li, C., Feng, K., Palmer, S., Appleton, P. L., Lang, S., McGloin, D., Huang, Z. & Nabi, G., 29 Jun 2017, In : Journal of Biophotonics. 10, 6-7, p. 911-918 8 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
228 Downloads (Pure)
2016

Combined changes in Wnt signalling response and contact inhibition induce altered proliferation in radiation treated intestinal crypts

Dunn, S. J., Osborne, J., Appleton, P. L. & Näthke, I., 1 Jun 2016, In : Molecular Biology of the Cell. 27, 11, p. 1863-1874 12 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
103 Downloads (Pure)

Paneth cell - rich regions separated by a cluster of Lgr5+ cells initiate crypt fission in the intestinal stem cell niche

Langlands, A. J., Almet, A. A., Appleton, P. L., Newton, I. P., Osborne, J. M. & Nathke, I. S., 27 Jun 2016, In : PLoS Biology. 14, 6, 31 p., e1002491.

Research output: Contribution to journalArticle

Open Access
File
28 Citations (Scopus)
231 Downloads (Pure)
2014

High-energy particle-induced tumorigenesis throughout the gastrointestinal tract

Trani, D., Nelson, S. A., Moon, B-H., Swedlow, J. J., Williams, E. M., Strawn, S. J., Appleton, P. L., Kallakury, B., Nathke, I. & Fornace, A. J., Feb 2014, In : Radiation Research. 181, 2, p. 162-71 10 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Spatiotemporal oscillations of Notch1, Dll1 and NICD are coordinated across the mouse PSM

Bone, R. A., Bailey, C. S. L., Wiedermann, G., Ferjentsik, Z., Appleton, P. L., Murray, P. J., Maroto, M. & Dale, J. K., 15 Dec 2014, In : Development. 141, 24, p. 4806-4816 11 p.

Research output: Contribution to journalArticle

Open Access
File
33 Citations (Scopus)
135 Downloads (Pure)
2012

A two-dimensional model of the colonic crypt accounting for the role of the basement membrane and pericryptal fibroblast sheath

Dunn, S-J., Appleton, P. L., Nelson, S. A., Nathke, I. S., Gavaghan, D. J. & Osborne, J. M., 2012, In : PLoS Computational Biology. 8, 5, e1002515.

Research output: Contribution to journalArticle

28 Citations (Scopus)

DVC1 (C1orf124) recruits the p97 protein segregase to sites of DNA damage

Davis, E. J., Lachaud, C., Appleton, P., MacArtney, T. J., Nathke, I. & Rouse, J., 2012, In : Nature Structural & Molecular Biology. 19, 11, p. 1093-1100 8 p.

Research output: Contribution to journalArticle

90 Citations (Scopus)

The microtubule poison vinorelbine kills cells independently of mitotic arrest and targets cells lacking the APC tumour suppressor more effectively

Klotz, D. M., Nelson, S. A., Kroboth, K., Newton, I. P., Radulescu, S., Ridgway, R. A., Sansom, O. J., Appleton, P. L. & Nathke, I. S., 15 Feb 2012, In : Journal of Cell Science. 125, P4, p. 887-95 9 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Tumorigenic fragments of APC cause dominant defects in directional cell migration in multiple model systems

Nelson, S. A., Li, Z., Newton, I. P., Fraser, D., Milne, R. E., Martin, D. M. A., Schiffmann, D., Yang, X., Dormann, D., Weijer, C. J., Appleton, P. L. & Nathke, I. S., Nov 2012, In : Disease Models & Mechanisms. 5, 6, p. 940-947 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)