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  • Julian Blow

3 tera-basepairs as a fundamental limit for robust DNA replication

Al Mamun, M., Albergante, L., Blow, J. & Newman, T., 30 Jun 2020, In : Physical Biology. 17, 4, 046002.

Research output: Contribution to journalArticle

Open Access
File
32 Downloads (Pure)

A Role for Dormant Origins in Tumor Suppression

Klotz-Noack, K. & Blow, J. J., 4 Mar 2011, In : Molecular Cell. 41, 5, p. 495-496 2 p.

Research output: Contribution to journalEditorial

6 Citations (Scopus)

Biphasic chromatin binding of histone chaperone FACT during eukaryotic chromatin DNA replication

Kundu, L. R., Seki, M., Watanabe, N., Murofushi, H., Furukohri, A., Waga, S., Score, A. J., Blow, J. J., Horikoshi, M., Enomoto, T. & Tada, S., Jun 2011, In : Biochimica et Biophysica Acta. Molecular Cell Research. 1813, 6, p. 1129-1136 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Buffered Qualitative Stability explains the robustness and evolvability of transcriptional networks

Albergante, L., Blow, J. J. & Newman, T. J., 2 Sep 2014, In : eLife. 3, p. 1-28 28 p., e02863.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
177 Downloads (Pure)

CDC-48/p97 Coordinates CDT-1 Degradation with GINS Chromatin Dissociation to Ensure Faithful DNA Replication

Franz, A., Orth, M., Pirson, P. A., Sonneville, R., Blow, J. J., Gartner, A., Stemmann, O. & Hoppe, T., 7 Oct 2011, In : Molecular Cell. 44, 1, p. 85-96 12 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

Cell cycle synchronization in xenopus egg extracts

Gillespie, P. J., Neusiedler, J., Creavin, K., Chadha, G. S. & Blow, J., 2016, Cell cycle oscillators: methods and protocols. Coutts, A. S. & Weston, L. (eds.). New York: Humana Press, p. 101-147 47 p. (Methods in Molecular Biology; vol. 1342).

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)

5 Citations (Scopus)

Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

Galanos, P., Vougas, K., Walter, D., Polyzos, A., Maya-Mendoza, A., Haagensen, E. J., Kokkalis, A., Roumelioti, F-M., Gagos, S., Tzetis, M., Canovas, B., Igea, A., Ahuja, A. K., Zellweger, R., Havaki, S., Kanavakis, E., Kletsas, D., Roninson, I. B., Garbis, S. D., Lopes, M. & 7 others, Nebreda, A., Thanos, D., Blow, J. J., Townsend, P., Sørensen, C. S., Bartek, J. & Gorgoulis, V. G., Jul 2016, In : Nature Cell Biology. 18, 7, p. 777-789 13 p.

Research output: Contribution to journalArticle

Open Access
File
107 Citations (Scopus)
629 Downloads (Pure)

Defects in the origin licensing checkpoint stresses cells exiting G0

Blow, J. J., 1 Jul 2019, In : Journal of Cell Biology. 218, 7, p. 2080-2081 2 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
85 Downloads (Pure)

Direct non transcriptional role of NF-Y in DNA replication

Benatti, P., Belluti, S., Miotto, B., Neusiedler, J., Dolfini, D., Drac, M., Basile, V., Schwob, E., Mantovani, R., Blow, J. J. & Imbriano, C., 1 Apr 2016, In : Biochimica et Biophysica Acta. Molecular Cell Research. 1863, 4, p. 673-685 13 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
142 Downloads (Pure)

Dormant Origins, the Licensing Checkpoint, and the Response to Replicative Stresses

McIntosh, D. & Blow, J. J., Oct 2012, In : Cold spring harbor perspectives in biology. 4, 10, 10 p., 012955.

Research output: Contribution to journalArticle

71 Citations (Scopus)

Dynamic interactions of high Cdt1 and geminin levels regulate S phase in early Xenopus embryos

Kisielewska, J. & Blow, J. J., 1 Jan 2012, In : Development. 139, 1, p. 63-74 12 p.

Research output: Contribution to journalArticle

Open Access
18 Citations (Scopus)
Open Access
27 Citations (Scopus)

Evidence for a mammalian late-G1 phase inhibitor of replication licensing distinct from geminin or Cdk activity

Sasaki, T., Li, A., Gillespie, P. J., Blow, J. J. & Gilbert, D. M., Sep 2011, In : Nucleus. 2, 5, p. 455-464

Research output: Contribution to journalArticle

4 Citations (Scopus)

How dormant origins promote complete genome replication

Blow, J. J., Ge, X. Q. & Jackson, D. A., Aug 2011, In : Trends in Biochemical Sciences. 36, 8, p. 405-414 10 p.

Research output: Contribution to journalReview article

144 Citations (Scopus)

Inevitability and containment of replication errors for eukaryotic genome lengths spanning Megabase to Gigabase

Al Mamun, M., Albergante, L., Moreno, A., Carrington, J. T., Blow, J. & Newman, T. J., 27 Sep 2016, In : Proceedings of the National Academy of Sciences. 113, 39, p. E5765-E5774 10 p.

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
467 Downloads (Pure)

MCM2-7 Form Double Hexamers at Licensed Origins in Xenopus Egg Extract

Gambus, A., Khoudoli, G. A., Jones, R. C. & Blow, J. J., 1 Apr 2011, In : Journal of Biological Chemistry. 286, 13, p. 11855-11864 10 p.

Research output: Contribution to journalArticle

95 Citations (Scopus)

Optimal Placement of Origins for DNA Replication

Karschau, J., Blow, J. J. & de Moura, A. P. S., 30 Jan 2012, In : Physical Review Letters. 108, 5, p. - 5 p., 058101.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Preparation and use of Xenopus egg extracts to study DNA replication and chromatin associated proteins

Gillespie, P. J., Gambus, A. & Blow, J. J., Jun 2012, In : Methods. 57, 2, p. 203-13 11 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)

Re-replication induced by geminin depletion occurs from G2 and is enhanced by checkpoint activation

Klotz-Noack, K., McIntosh, D., Schurch, N., Pratt, N. & Blow, J. J., 15 May 2012, In : Journal of Cell Science. 125, 10, p. 2436-2445 10 p.

Research output: Contribution to journalArticle

38 Citations (Scopus)

Reversal of DDK-mediated MCM phosphorylation by Rif1-PP1 regulates replication initiation and replisome stability independently of ATR/Chk1

Alver, R. C., Chadha, G. S., Gillespie, P. J. & Blow, J. J., 7 Mar 2017, In : Cell Reports. 18, 10, p. 2508-2520 13 p.

Research output: Contribution to journalArticle

Open Access
File
42 Citations (Scopus)
168 Downloads (Pure)

The contribution of dormant origins to genome stability: from cell biology to human genetics

Alver, R. C., Chadha, G. S. & Blow, J. J., Jul 2014, In : DNA Repair. 19, p. 182-189 8 p.

Research output: Contribution to journalArticle

Open Access
File
50 Citations (Scopus)
223 Downloads (Pure)

The dynamics of replication licensing in live Caenorhabditis elegans embryos

Sonneville, R., Querenet, M., Craig, A., Gartner, A. & Blow, J. J., 23 Jan 2012, In : Journal of Cell Biology. 196, 2, p. 233-246 14 p.

Research output: Contribution to journalArticle

Open Access
File
48 Citations (Scopus)
186 Downloads (Pure)

The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines

Gardner, N. J., Gillespie, P. J., Carrington, J. T., Shanks, E. J., McElroy, S. P., Haagensen, E. J., Frearson, J. A., Woodland, A. & Blow, J. J., 17 Aug 2017, In : Cell Chemical Biology. 24, 8, p. 981-992.e4 16 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
148 Downloads (Pure)

The KRAB Zinc Finger Protein Roma/Zfp157 Is a Critical Regulator of Cell-Cycle Progression and Genomic Stability

Ho, T. L. F., Guilbaud, G., Blow, J. J., Sale, J. E. & Watson, C. J., 26 Apr 2016, In : Cell Reports. 15, 4, p. 724-734 11 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
148 Downloads (Pure)
Open Access
File
11 Citations (Scopus)
293 Downloads (Pure)

Ubiquitinated Fancd2 recruits Fan1 to stalled replication forks to prevent genome instability

Lachaud, C., Moreno, A., Marchesi, F., Toth, R., Blow, J. J. & Rouse, J., 19 Feb 2016, In : Science. 351, 6275, p. 846-849 4 p.

Research output: Contribution to journalArticle

Open Access
61 Citations (Scopus)

Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells

Moreno, A., Carrington, J. T., Albergante, L., Al Mamun, M., Haagensen, E. J., Komseli, E-S., Gorgoulis, V. G., Newman, T. J. & Blow, J., 27 Sep 2016, In : Proceedings of the National Academy of Sciences. 113, 39, p. E5757-E5764 8 p.

Research output: Contribution to journalArticle

Open Access
File
49 Citations (Scopus)
409 Downloads (Pure)

Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1

Poh, W. T., Chadha, G. S., Gillespie, P. J., Kaldis, P. & Blow, J. J., 8 Jan 2014, In : Open Biology. 4, January, 130138.

Research output: Contribution to journalArticle

Open Access
File
21 Citations (Scopus)
140 Downloads (Pure)
Open Access
File
3 Citations (Scopus)
179 Downloads (Pure)

Xenopus Mcm10 is a CDK-substrate required for replication fork stability

Chadha, G. S., Gambus, A., Gillespie, P. J. & Blow, J., 2016, In : Cell Cycle. 15, 16, p. 2183-2195 13 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
234 Downloads (Pure)