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Identification of caveolar resident proteins in ventricular myocytes using a quantitative proteomic approach: dynamic changes in caveolar composition following adrenoceptor activation
Wypijewski, K. J., Tinti, M., Chen, W., Lamont, D., Ashford, M. L. J., Calaghan, S. C. & Fuller, W., Mar 2015, In: Molecular & Cellular Proteomics. 14, 3, p. 596-608 13 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
Identification of compounds acting as negative allosteric modulators of the LPA 1 receptor
Ellery, J., Dickson, L., Cheung, T., Ciuclan, L., Bunyard, P., Mack, S., Buffham, W. J., Farnaby, W., Mitchell, P., Brown, D., Isaacs, R. & Barnes, M., 15 Aug 2018, In: European Journal of Pharmacology. 833, p. 8-15 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)585 Downloads (Pure) -
Identification of crop cultivars with consistently high lignocellulosic sugar release requires the use of appropriate statistical design and modelling
Oakey, H., Shafiei, R., Comadran, J., Uzrek, N., Cullis, B., Gomez, L. D., Whitehead, C., McQueen-Mason, S. J., Waugh, R. & Halpin, C., 21 Dec 2013, In: Biotechnology for Biofuels. 6, 1, p. 1-12 12 p., 185.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)138 Downloads (Pure) -
Identification of different specificity requirements between SGK1 and PKBα
Murray, J. T., Cummings, L. A., Bloomberg, G. B. & Cohen, P., 14 Feb 2005, In: FEBS Letters. 579, 5, p. 991-994 4 p.Research output: Contribution to journal › Article › peer-review
Open Access39 Citations (Scopus) -
Identification of Elg1 interaction partners and effects on post-replication chromatin re-formation
Gali, V. K., Dickerson, D., Katou, Y., Fujiki, K., Shirahige, K., Owen-Hughes, T., Kubota, T. & Donaldson, A. D., Nov 2018, In: PLoS Genetics. 14, 11, p. 1-20 20 p., e1007783.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)128 Downloads (Pure) -
Identification of Endogenous Adenomatous Polyposis Coli Interaction Partners and β-Catenin-Independent Targets by Proteomics
Popow, O., Paulo, J. A., Tatham, M., Volk, M., Rojas-Fernandez, A., Loyer, N., Newton, I., Januschke, J., Haigis, K. M. & Nathke, I., Sep 2019, In: Molecular Cancer Research. 17, 9, p. 1828-1841 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Citations (Scopus)56 Downloads (Pure) -
Identification of ester-linked ubiquitylation sites during TLR7 signalling increases the number of inter-ubiquitin linkages from 8 to 12
McCrory, E. H., Akimov, V., Cohen, P. & Blagoev, B., 7 Dec 2022, In: Biochemical Journal. 479, 23, p. 2419-2431 13 p., BCJ20220510.Research output: Contribution to journal › Article › peer-review
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Identification of fatty acid binding protein 4 as an adipokine that regulates insulin secretion during obesity
Wu, L. E., Samocha-Bonet, D., Whitworth, P. T., Fazakerley, D. J., Turner, N., Biden, T. J., James, D. E. & Cantley, J., Jul 2014, In: Molecular Metabolism. 3, 4, p. 465-473 9 p.Research output: Contribution to journal › Article › peer-review
Open Access76 Citations (Scopus) -
Identification of filamin C as a new physiological substrate of PKβα using KESTREL
Murray, J. T., Campbell, D. G., Peggie, M., Alfonso, M. & Cohen, P., 15 Dec 2004, In: Biochemical Journal. 384, 3, p. 489-494 6 p.Research output: Contribution to journal › Article › peer-review
37 Citations (Scopus) -
Identification of Fitness Determinants during Energy-Limited Growth Arrest in Pseudomonas aeruginosa
Basta, D. W., Bergkessel, M. & Newman, D. K., Dec 2017, In: MBio. 8, 6, p. 1-18 18 p., e01170-17.Research output: Contribution to journal › Article › peer-review
Open AccessFile31 Citations (Scopus)56 Downloads (Pure) -
Identification of functional residues and secondary structure from protein multiple sequence alignment
Livingstone, C. D. & Barton, G. J., 1996, In: Methods in Enzymology. 266, p. 497-512 16 p.Research output: Contribution to journal › Article › peer-review
61 Citations (Scopus) -
Identification of genetic polymorphisms at the glutathione S-transferase Pi locus and association with susceptibility to bladder, testicular and prostate cancer
Harries, L. W., Stubbins, M. J., Forman, D., Howard, G. C. W. & Wolf, C. R., 1 Apr 1997, In: Carcinogenesis. 18, 4, p. 641-644 4 p.Research output: Contribution to journal › Article › peer-review
704 Citations (Scopus) -
Identification of Genetic Variation Influencing Metformin Response in a Multi-Ancestry Genome-Wide Association Study in the Diabetes Prevention Program (DPP)
Li, J. H., Perry, J. A., Jablonski, K. A., Srinivasan, S., Chen, L., Todd, J. N., Harden, M., Mercader, J. M., Pan, Q., Dawed, A. Y., Yee, S. W., Pearson, E. R., Giacomini, K. M., Giri, A., Hung, A. M., Xiao, S., Williams, L. K., Franks, P. W., Hanson, R. L., Kahn, S. E., & 3 others , 16 Dec 2022, (E-pub ahead of print) In: Diabetes.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Downloads (Pure) -
Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis
Thomas, M. G., De Rycker, M., Ajakane, M., Albrecht, S., Álvarez-Pedraglio, A. I., Boesche, M., Brand, S., Campbell, L., Cantizani-Perez, J., Cleghorn, L. A. T., Copley, R. C. B., Crouch, S. D., Daugan, A., Drewes, G., Ferrer, S., Ghidelli-Disse, S., Gonzalez, S., Gresham, S. L., Hill, A. P., Hindley, S. J., & 32 others , 14 Feb 2019, In: Journal of Medicinal Chemistry. 62, 3, p. 1180-1202 23 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile23 Citations (Scopus)211 Downloads (Pure) -
Identification of head and neck squamous cell carcinoma biomarker candidates through proteomic analysis of cancer cell secretome
Marimuthu, A., Chavan, S., Sathe, G., Sahasrabuddhe, N. A., Srikanth, S. M., Renuse, S., Ahmad, S., Radhakrishnan, A., Barbhuiya, M. A., Kumar, R. V., Harsha, H. C., Sidransky, D., Califano, J., Pandey, A. & Chatterjee, A., Nov 2013, In: Biochimica et Biophysica Acta - Proteins and Proteomics. 1834, 11, p. 2308-2316 9 p.Research output: Contribution to journal › Article › peer-review
48 Citations (Scopus) -
Identification of high levels of protein phosphatase-1 in rat liver nuclei
Kuret, J., Bell, H. & Cohen, P., 28 Jul 1986, In: FEBS Letters. 203, 2, p. 197-202 6 p.Research output: Contribution to journal › Article › peer-review
Open Access55 Citations (Scopus) -
Identification of high levels of type 1 and type 2A protein phosphatases in higher plants
MacKintosh, C. & Cohen, P., 1989, In: Biochemical Journal. 262, 1, p. 335-339 5 p.Research output: Contribution to journal › Article › peer-review
123 Citations (Scopus) -
Identification of hnRNP P2 as TLS/FUS using electrospray mass spectrometry
Calvio, C., Neubauer, G., Mann, M. & Lamond, A. I., Sep 1995, In: RNA. 1, 7, p. 724-733 10 p.Research output: Contribution to journal › Article › peer-review
105 Citations (Scopus) -
Identification of hSRP1α as a functional receptor for nuclear localization sequences
Weis, K., Mattaj, I. W. & Lamond, A. I., 19 May 1995, In: Science. 268, 5213, p. 1049-1053 5 p.Research output: Contribution to journal › Article › peer-review
306 Citations (Scopus) -
Identification of human miRNA precursors that resemble box C/D snoRNAs
Ono, M., Scott, M. S., Yamada, K., Avolio, F., Barton, G. J. & Lamond, A. I., May 2011, In: Nucleic Acids Research. 39, 9, p. 3879-3891 13 p.Research output: Contribution to journal › Article › peer-review
107 Citations (Scopus) -
Identification of inhibitors of an unconventional Trypanosoma brucei kinetochore kinase
Torrie, L., Zuccotto, F., Robinson, D., Gray, D., Gilbert, I. & De Rycker, M., 31 May 2019, In: PLoS ONE. 14, 5, p. 1-16 16 p., e0217828.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)115 Downloads (Pure) -
Identification of Inhibitors of the Leishmania cdc2-Related Protein Kinase CRK3
Cleghorn, L. A. T., Woodland, A., Collie, I. T., Torrie, L. S., Norcross, N., Luksch, T., Mpamhanga, C., Walker, R. G., Mottram, J. C., Brenk, R., Frearson, J. A., Gilbert, I. H. & Wyatt, P. G., 9 Dec 2011, In: ChemMedChem. 6, 12, p. 2214-2224 11 p.Research output: Contribution to journal › Article › peer-review
44 Citations (Scopus)7 Downloads (Pure) -
Identification of insulin-stimulated protein kinase-1 as the rabbit equivalent of rskmo-2: identification of two threonines phosphorylated during activation by mitogen-activated protein kinase
Sutherland, C., Campbell, D. G. & Cohen, P., 1993, In: European Journal of Biochemistry. 212, 2, p. 581-588 8 p.Research output: Contribution to journal › Article › peer-review
113 Citations (Scopus) -
Identification of intraneuronal amyloid beta oligomers in locus coeruleus neurons of Alzheimer's patients and their potential impact on inhibitory neurotransmitter receptors and neuronal excitability
Kelly, L., Seifi, M., Ma, R., Mitchell, S. J., Rudolph, U., Viola, K. L., Klein, W. L., Lambert, J. J. & Swinny, J. D., 2 May 2021, In: Neuropathology and Applied Neurobiology. 47, 4, p. 488-505 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Citations (Scopus)61 Downloads (Pure) -
Identification of in vitro and in vivo phosphorylation sites in the catalytic subunit of the DNA-dependent protein kinase
Douglas, P., Sapkota, G. P., Morrice, N., Yu, Y., Goodarzi, A. A., Merkle, D., Meek, K., Alessi, D. R. & Lees-Miller, S. P., 19 Aug 2002, In: Biochemical Journal. 368, 1, p. 243-251 9 p.Research output: Contribution to journal › Article › peer-review
159 Citations (Scopus) -
Identification of key functional residues in the active site of human beta 1, 4-Galactosyltransferase 7: a major enzyme in the glycosaminoglycan synthesis pathway
Talhaoui, I., Bui, C., Oriol, R., Mulliert, G., Gulberti, S., Netter, P., Coughtrie, M. W. H., Ouzzine, M. & Fournel-Gigleux, S., 26 Nov 2010, In: Journal of Biological Chemistry. 285, 48, p. 37342-37358 17 p.Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus) -
Identification of KIAA1018/FAN1, a DNA Repair Nuclease Recruited to DNA Damage by Monoubiquitinated FANCD2
MacKay, C., Declais, A-C., Lundin, C., Agostinho, A., Deans, A. J., MacArtney, T. J., Hofmann, K., Gartner, A., West, S. C., Helleday, T., Lilley, D. M. J. & Rouse, J., 9 Jul 2010, In: Cell. 142, 1, p. 65-76 12 p.Research output: Contribution to journal › Article › peer-review
236 Citations (Scopus) -
Identification of lacustrine dissolved oxygen depletion by acoustic remote sensing
Wewetzer, S. F. K. & Duck, R. W., Apr 1995, In: Physics and Chemistry of the Earth. 20, 2, p. 163-167Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Identification of lead vacancy defects in lead halide perovskites
Keeble, D., Wiktor, J., Pathak, S. K., Phillips, L. J., Dickmann, M., Durose, K., Snaith, H. J. & Egger, W., 22 Sep 2021, In: Nature Communications. 12, 7 p., 5566 .Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Citations (Scopus)34 Downloads (Pure) -
Identification of lectin counter-receptors on cell membranes by proximity labelling
Wu, G., Nagala, M. & Crocker, P. R., 1 Sep 2017, In: Glycobiology. 27, 9, p. 800-805 6 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)139 Downloads (Pure) -
Identification of Leishmania major UDP-Sugar Pyrophosphorylase Inhibitors Using Biosensor-Based Small Molecule Fragment Library Screening
Prakash, O., Führing, J., Post, J., Shepherd, S. M., Eadsforth, T. C., Gray, D., Fedorov, R. & Routier, F. H., 12 Mar 2019, In: Molecules. 24, 5, p. 1-16 16 p., 996.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)161 Downloads (Pure) -
Identification of loci associated with late-onset psoriasis using dense genotyping of immune-related regions
Hébert, H. L., Bowes, J., Smith, R. L., Flynn, E., Parslew, R., Alsharqi, A., McHugh, N. J., Barker, J. N. W. N., Griffiths, C. E. M., Barton, A. & Warren, R. B., 1 Apr 2015, In: British Journal of Dermatology. 172, 4, p. 933-939 7 p.Research output: Contribution to journal › Article › peer-review
16 Citations (Scopus) -
Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins
Stokoe, D., Engel, K., Campbell, D. G., Cohen, P. & Gaestel, M., 30 Nov 1992, In: FEBS Letters. 313, 3, p. 307-313 7 p.Research output: Contribution to journal › Article › peer-review
Open Access471 Citations (Scopus) -
Identification of membrane-bound and secreted proteins from Echinococcus granulosus by signal sequence trap
Rosenzvit, M. C., Zhang, W., Motazedian, H., Smyth, D., Pearson, M., Loukas, A., Jones, M. K. & McManus, D. P., 1 Jan 2006, In: International Journal for Parasitology. 36, 1, p. 123-130 8 p.Research output: Contribution to journal › Article › peer-review
10 Citations (Scopus) -
Identification of Morpholino Thiophenes as Novel Mycobacterium tuberculosis Inhibitors, Targeting QcrB
Cleghorn, L., Ray, P., Odingo, J., Kumar, A., Wescott, H., Korkegian, A., Masquelin, T., Lopez Moure, A., Wilson, C., Davis, S., Huggett, M., Turner, P., Smith, A., Epemolu, R., Zuccotto, F., Riley, J., Scullion, S., Shishikura, Y., Ferguson, L., Rullas, J., & 6 others , 9 Aug 2018, In: Journal of Medicinal Chemistry. 61, 15, p. 6592-6608 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile35 Citations (Scopus)208 Downloads (Pure) -
Identification of movement strategies during the sit-to-walk movement in patients with knee osteoarthritis
Komaris, D. S., Govind, C., Murphy, A., Ewen, A. & Riches, P., Apr 2018, In: Journal of Applied Biomechanics. 34, 2, p. 96-103 8 p.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
Identification of multiple distinct Snf2 subfamilies with conserved structural motifs
Flaus, A., Martin, D. M. A., Barton, G. J. & Owen-Hughes, T., 2006, In: Nucleic Acids Research. 34, 10, p. 2887-905 19 p.Research output: Contribution to journal › Article › peer-review
File511 Citations (Scopus)172 Downloads (Pure) -
Identification of N-(4-piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide (AT7519), a novel cyclin dependent kinase inhibitor using fragment-based X-ray crystallography and structure based drug design
Wyatt, P. G., Woodhead, A. J., Berdini, V., Boulstridge, J. A., Carr, M. G., Cross, D. M., Davis, D. J., Devine, L. A., Early, T. R., Feltell, R. E., Lewis, E. J., McMenamin, R. L., Navarro, E. F., O'Brien, M. A., O'Reilly, M., Reule, M., Saxty, G., Seavers, L. C. A., Smith, D-M., Squires, M. S., & 3 others , 28 Aug 2008, In: Journal of Medicinal Chemistry. 51, 16, p. 4986-4999 14 p.Research output: Contribution to journal › Article › peer-review
289 Citations (Scopus) -
Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease
CHD Exome+ Consortium, EPIC-InterAct Consortium, Michigan Biobank, Zhao, W., Rasheed, A., Tikkanen, E., Lee, J-J., Butterworth, A. S., Howson, J. M. M., Assimes, T. L., Chowdhury, R., Orho-Melander, M., Damrauer, S., Small, A., Asma, S., Imamura, M., Yamauch, T., Chambers, J. C., Chen, P., Sapkota, B. R., & 73 others , 2017, In: Nature Genetics. 49, 10, p. 1450-1457 8 p.Research output: Contribution to journal › Article › peer-review
138 Citations (Scopus) -
Identification of novel functional and spatial associations between sphingosine kinase 1, sphingosine 1-phosphate receptors and other signaling proteins that affect prognostic outcome in estrogen receptor-positive breast cancer
Ohotski, J., Edwards, J., Elsberger, B., Watson, C., Orange, C., Mallon, E., Pyne, S. & Pyne, N. J., 1 Feb 2013, In: International Journal of Cancer. 132, 3, p. 605-616 12 p.Research output: Contribution to journal › Article › peer-review
38 Citations (Scopus) -
Identification of novel inhibitors of the type I interferon induction pathway using cell-based high-throughput screening
Gage, Z. O., Vasou, A., Gray, D. W., Randall, R. E. & Adamson, C. S., 1 Oct 2016, In: Journal of Biomolecular Screening. 21, 9, p. 978-988 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)167 Downloads (Pure) -
Identification of novel inhibitors of UDP-Glc 4 '-epimerase, a validated drug target for African sleeping sickness
Urbaniak, M. D., Tabudravu, J. N., Msaki, A., Matera, K. M., Brenk, R., Jaspars, M. & Ferguson, M. A. J., 15 Nov 2006, In: Bioorganic & Medicinal Chemistry Letters. 16, 22, p. 5744-5747 4 p.Research output: Contribution to journal › Article › peer-review
32 Citations (Scopus) -
Identification of novel loci associated with hip shape: a meta-analysis of genome-wide association studies
Baird, D. A., Evans, D. S., Kamanu, F. K., Gregory, J. S., Saunders, F. R., Giuraniuc, C. V., Barr, R. J., Aspden, R. M., Jenkins, D., Kiel, D. P., Orwoll, E. S., Cummings, S. R., Lane, N. E., Mullin, B. H., Williams, F. M. K., Richards, J. B., Wilson, S. G., Spector, T. D., Faber, B. G., Lawlor, D. A., & 10 others , 14 Feb 2019, In: Journal of Bone and Mineral Research. 34, 2, p. 241-251 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile34 Citations (Scopus)160 Downloads (Pure) -
Identification of novel pathways of osimertinib disposition and potential implications for the outcome of lung cancer therapy
MacLeod, A. K., Lin, D., Huang, J. T-J., McLaughlin, L. A., Henderson, C. J. & Wolf, C. R., May 2018, In: Clinical Cancer Research. 24, 9, p. 2138-2147 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)200 Downloads (Pure) -
Identification of novel phosphorylation sites in MSK1 by precursor ion scanning MS
McCoy, C. E., Macdonald, A., Morrice, N. A., Campbell, D. G., Deak, M., Toth, R., McIlrath, J. & Arthur, J. S. C., 15 Mar 2007, In: Biochemical Journal. 402, 3, p. 491-501 11 p.Research output: Contribution to journal › Article › peer-review
42 Citations (Scopus) -
Identification of novel phosphorylation sites required for activation of MAPKAP kinase-2
Ben-Levy, R., Leighton, I. A., Doza, Y. N., Attwood, P., Morrice, N., Marshall, C. J. & Cohen, P., 1 Jan 1995, In: EMBO Journal. 14, 23, p. 5920-5930 11 p.Research output: Contribution to journal › Article › peer-review
162 Citations (Scopus) -
Identification of novel polymorphisms in the glucokinase and glucose-6-phosphatase genes in infants who died suddenly and unexpectedly
Forsyth, L., Hume, R., Howatson, A., Busuttil, A. & Burchell, A., Aug 2005, In: Journal of Molecular Medicine. 83, 8, p. 610-618 9 p.Research output: Contribution to journal › Article › peer-review
25 Citations (Scopus) -
Identification of novel roles of the cytochrome P450 system in early embryogenesis: effects on vasculogenesis and retinoic acid homeostasis
Otto, D. M. E., Henderson, C. J., Carrie, D., Davey, M., Gundersen, T. E., Blomhoff, R., Adams, R. H., Tickle, C. & Wolf, C. R., Sep 2003, In: Molecular and Cellular Biology. 23, 17, p. 6103-6116 14 p.Research output: Contribution to journal › Article › peer-review
158 Citations (Scopus) -
Identification of Novel Trypanosoma cruzi Proteasome Inhibitors Using a Luminescence-Based High-Throughput Screening Assay
Zmuda, F., Sastry, L., Shepherd, S. M., Jones, D., Scott, A., Craggs, P. D., Cortes, A., Gray, D. W., Torrie, L. S. & De Rycker, M., Sep 2019, In: Antimicrobial Agents and Chemotherapy. 63, 9, 15 p., e00309-19.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)100 Downloads (Pure) -
Identification of nucleolar associated chromatin loci reveals clues for nuclear architecture
van Koningsbruggen, S., Martin, D. M. A., Ariyurek, Y., den Dunnen, J. T. & Lamond, A. I., 2009, In: Cellular Oncology. 31, 2, p. 105-106 2 p., O16.Research output: Contribution to journal › Article › peer-review