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• Xenopus Mcm10 is a CDK-substrate required for replication fork stability

  Chadha, G. S., Gambus, A., Gillespie, P. J. & Blow, J., 2016, In: Cell Cycle. 15, 16, p. 2183-2195 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Xenopus
  • S Phase
  • Chromatin
  • Replication Origin
  • Ovum
  14 Citations (Scopus)

  258 Downloads (Pure)

• Xenopus cell-free extracts and their contribution to the study of DNA replication and other complex biological processes

  Blow, J. J. & Laskey, R. A., 2016, In: International Journal of Developmental Biology. 60, 7-9, p. 201-207 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cell Extracts
  • Xenopus
  • Ovum
  • DNA Replication
  • Biological Phenomena
  4 Citations (Scopus)

  194 Downloads (Pure)

• Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1

  Poh, W. T., Chadha, G. S., Gillespie, P. J., Kaldis, P. & Blow, J. J., 8 Jan 2014, In: Open Biology. 4, January, 130138.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Protein Phosphatase 1
  • Chromosomes
  • Xenopus
  • S Phase
  • Maintenance
  21 Citations (Scopus)

  152 Downloads (Pure)

• Unreplicated DNA remaining from unperturbed S phases passes through mitosis for resolution in daughter cells

  Moreno, A., Carrington, J. T., Albergante, L., Al Mamun, M., Haagensen, E. J., Komseli, E-S., Gorgoulis, V. G., Newman, T. J. & Blow, J., 27 Sep 2016, In: Proceedings of the National Academy of Sciences. 113, 39, p. E5757-E5764 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Replication Origin
  • Mitosis
  • S Phase
  • DNA
  • Yeasts
  56 Citations (Scopus)

  435 Downloads (Pure)

• Ubiquitinated Fancd2 recruits Fan1 to stalled replication forks to prevent genome instability

  Lachaud, C., Moreno, A., Marchesi, F., Toth, R., Blow, J. J. & Rouse, J., 19 Feb 2016, In: Science. 351, 6275, p. 846-849 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Genomic Instability
  • DNA Replication
  • Personnel Selection
  • Ubiquitination
  • Chromosome Aberrations
  65 Citations (Scopus)

• The SMC-5/6 Complex and the HIM-6 (BLM) Helicase Synergistically Promote Meiotic Recombination Intermediate Processing and Chromosome Maturation during Caenorhabditis elegans Meiosis

  Hong, Y., Sonneville, R., Agostinho, A., Meier, B., Wang, B., Blow, J. J. & Gartner, A., 24 Mar 2016, In: PLoS Genetics. 12, 3, e1005872.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Chromosomes, Human, Pair 5
  • Meiosis
  • Caenorhabditis elegans
  • recombination
  • chromosome
  13 Citations (Scopus)

  307 Downloads (Pure)

• The KRAB Zinc Finger Protein Roma/Zfp157 Is a Critical Regulator of Cell-Cycle Progression and Genomic Stability

  Ho, T. L. F., Guilbaud, G., Blow, J. J., Sale, J. E. & Watson, C. J., 26 Apr 2016, In: Cell Reports. 15, 4, p. 724-734 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Epithelial Cells
  • Zinc Fingers
  • Genomic Instability
  • Cells
  • Zinc
  4 Citations (Scopus)

  158 Downloads (Pure)

• The dynamics of replication licensing in live Caenorhabditis elegans embryos

  Sonneville, R., Querenet, M., Craig, A., Gartner, A. & Blow, J. J., 23 Jan 2012, In: Journal of Cell Biology. 196, 2, p. 233-246 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  50 Citations (Scopus)

  195 Downloads (Pure)

• The contribution of dormant origins to genome stability: from cell biology to human genetics

  Alver, R. C., Chadha, G. S. & Blow, J. J., Jul 2014, In: DNA Repair. 19, p. 182-189 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cytology
  • Genetics
  • Human Genetics
  • Genomic Instability
  • Licensure
  53 Citations (Scopus)

  243 Downloads (Pure)

• Re-replication induced by geminin depletion occurs from G2 and is enhanced by checkpoint activation

  Klotz-Noack, K., McIntosh, D., Schurch, N., Pratt, N. & Blow, J. J., 15 May 2012, In: Journal of Cell Science. 125, 10, p. 2436-2445 10 p.

  Research output: Contribution to journal › Article › peer-review
  40 Citations (Scopus)

• Preparation and use of Xenopus egg extracts to study DNA replication and chromatin associated proteins

  Gillespie, P. J., Gambus, A. & Blow, J. J., Jun 2012, In: Methods. 57, 2, p. 203-13 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Xenopus
  • Ovum
  • DNA Replication
  • Chromatin
  • Cell Cycle
  38 Citations (Scopus)

• Optimal Placement of Origins for DNA Replication

  Karschau, J., Blow, J. J. & de Moura, A. P. S., 30 Jan 2012, In: Physical Review Letters. 108, 5, p. - 5 p., 058101.

  Research output: Contribution to journal › Article › peer-review
  13 Citations (Scopus)

• MCM2-7 Form Double Hexamers at Licensed Origins in Xenopus Egg Extract

  Gambus, A., Khoudoli, G. A., Jones, R. C. & Blow, J. J., 1 Apr 2011, In: Journal of Biological Chemistry. 286, 13, p. 11855-11864 10 p.

  Research output: Contribution to journal › Article › peer-review
  95 Citations (Scopus)

• Inevitability and containment of replication errors for eukaryotic genome lengths spanning Megabase to Gigabase

  Al Mamun, M., Albergante, L., Moreno, A., Carrington, J. T., Blow, J. & Newman, T. J., 27 Sep 2016, In: Proceedings of the National Academy of Sciences. 113, 39, p. E5765-E5774 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Replication Origin
  • Genome
  • Genome Size
  • Datasets
  • Yeasts
  17 Citations (Scopus)

  530 Downloads (Pure)

• How dormant origins promote complete genome replication

  Blow, J. J., Ge, X. Q. & Jackson, D. A., Aug 2011, In: Trends in Biochemical Sciences. 36, 8, p. 405-414 10 p.

  Research output: Contribution to journal › Review article › peer-review
  148 Citations (Scopus)

• Evidence for a mammalian late-G1 phase inhibitor of replication licensing distinct from geminin or Cdk activity

  Sasaki, T., Li, A., Gillespie, P. J., Blow, J. J. & Gilbert, D. M., Sep 2011, In: Nucleus. 2, 5, p. 455-464

  Research output: Contribution to journal › Article › peer-review

  • Geminin
  • Licensure
  • G1 Phase
  • S Phase
  • Cell Extracts
  4 Citations (Scopus)

• Dynamic SUMO modification regulates mitotic chromosome assembly and cell cycle progression in Caenorhabditis elegans

  Pelisch, F., Sonneville, R., Pourkarimi, E., Agostinho, A., Blow, J. J., Gartner, A. & Hay, R. T., 5 Dec 2014, In: Nature Communications. 5, 12 p., 5485.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • chromosomes
  • Chromosomes
  • progressions
  • Caenorhabditis elegans
  • Ubiquitin
  32 Citations (Scopus)

• Dynamic interactions of high Cdt1 and geminin levels regulate S phase in early Xenopus embryos

  Kisielewska, J. & Blow, J. J., 1 Jan 2012, In: Development. 139, 1, p. 63-74 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  18 Citations (Scopus)

• Dormant Origins, the Licensing Checkpoint, and the Response to Replicative Stresses

  McIntosh, D. & Blow, J. J., Oct 2012, In: Cold spring harbor perspectives in biology. 4, 10, 10 p., 012955.

  Research output: Contribution to journal › Article › peer-review

  • Licensure
  • Meier-Gorlin syndrome
  • Cell proliferation
  • Maintenance
  • Replication Origin
  75 Citations (Scopus)

• Direct non transcriptional role of NF-Y in DNA replication

  Benatti, P., Belluti, S., Miotto, B., Neusiedler, J., Dolfini, D., Drac, M., Basile, V., Schwob, E., Mantovani, R., Blow, J. J. & Imbriano, C., 1 Apr 2016, In: Biochimica et Biophysica Acta. Molecular Cell Research. 1863, 4, p. 673-685 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • DNA Replication
  • S Phase
  • DNA
  • Cell-Free System
  • Xenopus
  8 Citations (Scopus)

  170 Downloads (Pure)

• Defects in the origin licensing checkpoint stresses cells exiting G0

  Blow, J. J., 1 Jul 2019, In: Journal of Cell Biology. 218, 7, p. 2080-2081 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Licensure
  • Replication Origin
  2 Citations (Scopus)

  93 Downloads (Pure)

• Chronic p53-independent p21 expression causes genomic instability by deregulating replication licensing

  Galanos, P., Vougas, K., Walter, D., Polyzos, A., Maya-Mendoza, A., Haagensen, E. J., Kokkalis, A., Roumelioti, F-M., Gagos, S., Tzetis, M., Canovas, B., Igea, A., Ahuja, A. K., Zellweger, R., Havaki, S., Kanavakis, E., Kletsas, D., Roninson, I. B., Garbis, S. D., Lopes, M. & 7 others, Nebreda, A., Thanos, D., Blow, J. J., Townsend, P., Sørensen, C. S., Bartek, J. & Gorgoulis, V. G., Jul 2016, In: Nature Cell Biology. 18, 7, p. 777-789 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Genomic Instability
  • Licensure
  • Cyclin-Dependent Kinase Inhibitor p21
  • Neoplasms
  • Replication Origin
  114 Citations (Scopus)

  700 Downloads (Pure)

• Cell cycle synchronization in xenopus egg extracts

  Gillespie, P. J., Neusiedler, J., Creavin, K., Chadha, G. S. & Blow, J., 2016, Cell cycle oscillators: methods and protocols. Coutts, A. S. & Weston, L. (eds.). New York: Humana Press, p. 101-147 47 p. (Methods in Molecular Biology; vol. 1342).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

  • Xenopus
  • Ovum
  • Cell Cycle
  • Eukaryotic Cells
  • Cell-Free System
  5 Citations (Scopus)

• CDC-48/p97 Coordinates CDT-1 Degradation with GINS Chromatin Dissociation to Ensure Faithful DNA Replication

  Franz, A., Orth, M., Pirson, P. A., Sonneville, R., Blow, J. J., Gartner, A., Stemmann, O. & Hoppe, T., 7 Oct 2011, In: Molecular Cell. 44, 1, p. 85-96 12 p.

  Research output: Contribution to journal › Article › peer-review
  62 Citations (Scopus)

• Buffered Qualitative Stability explains the robustness and evolvability of transcriptional networks

  Albergante, L., Blow, J. J. & Newman, T. J., 2 Sep 2014, In: eLife. 3, 28 p., e02863.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Gene Regulatory Networks
  • Physiological Adaptation
  • Neoplasms
  • Cells
  • Genes
  17 Citations (Scopus)

  190 Downloads (Pure)

• Biphasic chromatin binding of histone chaperone FACT during eukaryotic chromatin DNA replication

  Kundu, L. R., Seki, M., Watanabe, N., Murofushi, H., Furukohri, A., Waga, S., Score, A. J., Blow, J. J., Horikoshi, M., Enomoto, T. & Tada, S., Jun 2011, In: Biochimica et Biophysica Acta. Molecular Cell Research. 1813, 6, p. 1129-1136 8 p.

  Research output: Contribution to journal › Article › peer-review
  8 Citations (Scopus)

• A Role for Dormant Origins in Tumor Suppression

  Klotz-Noack, K. & Blow, J. J., 4 Mar 2011, In: Molecular Cell. 41, 5, p. 495-496 2 p.

  Research output: Contribution to journal › Editorial › peer-review
  6 Citations (Scopus)