Find Research outputs

Search results

• A missense mutation in the catalytic domain of O-GlcNAc transferase links perturbations in protein O-GlcNAcylation to X-linked intellectual disability

  Pravata, V. M., Gundogdu, M., Bartual, S. G., Ferenbach, A. T., Stavridis, M., Õunap, K., Pajusalu, S., Žordania, R., Wojcik, M. H. & van Aalten, D. M. F., 7 Nov 2019, In: FEBS Letters. 594, 4, p. 717-727 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • O-GlcNAc transferase
  • Missense Mutation
  • Intellectual Disability
  • Catalytic Domain
  • X ray crystallography
  8 Citations (Scopus)

  14 Downloads (Pure)

• A Mixed Analytical/Numerical Method for Velocity and Heat Transfer of Laminar Power-Law Fluids

  Li, B., Zheng, L., Lin, P., Wang, Z. & Liao, M., 3 Aug 2016, In: Numerical Mathematics: Theory, Methods and Applications. 9, 3, p. 315-336 22 p.

  Research output: Contribution to journal › Article › peer-review

  • Power-law Fluid
  • Analytical Methods
  • Heat Transfer
  • Boundary layers
  • Boundary Layer
  6 Citations (Scopus)

• A mixed methods approach to understanding funder trust and due diligence processes in online crowdfunding investment

  Jones, H. S. & Moncur, W., Feb 2020, In: ACM Transactions on Social Computing. 3, 1, p. 1-29 29 p., 3.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Due Diligence
  • Crowdfunding
  • Assurance
  • Liking
  • Investment Decision-making
  52 Downloads (Pure)

• A mixed methods comparative evaluation of a low cost otoscope (Arclight) with a traditional device in twenty-one clinicians

  Hey, S. Y., Buckley, J. C., Shahsavari, S., Kousha, O., Haddow, K. A., Blaikie, A. & Walker, F. D. L., 1 Nov 2019, In: Clinical Otolaryngology. 44, 6, p. 1101-1104 4 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  File

  • Otoscopes
  • Ear Diseases
  • Costs and Cost Analysis
  • Equipment and Supplies
  • Hearing Loss
  2 Citations (Scopus)

  18 Downloads (Pure)

• A mobile phone based personal narrative system

  Black, R., Waller, A., Tintarev, N., Reiter, E. & Reddington, J., 2011, ASSETS'11: proceedings of the 13th International ACM SIGACCESS Conference on Computers and Accessibility. 24-26 October 2011, Dundee, United Kingdom. New York: Association for Computing Machinery, p. 171-178 8 p.

  Research output: Chapter in Book/Report/Conference proceeding › Other chapter contribution

  • Cellular telephones
  • Communication
  • Servers
  • Switches
  • Feedback
  7 Citations (Scopus)

• A mobile phone intervention to reduce binge drinking among disadvantaged men: study protocol for a randomised controlled cost-effectiveness trial

  Crombie, I. K., Irvine, L., Williams, B., Sniehotta, F. F., Petrie, D., Evans, J. M. M., Emslie, C., Jones, C., Ricketts, I. W., Humphris, G., Norrie, J., Rice, P. & Slane, P. W., 19 Dec 2014, In: Trials. 15, 8 p., 494.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Binge Drinking
  • Cell Phone
  • Vulnerable Populations
  • Cost-Benefit Analysis
  • Text Messaging
  7 Citations (Scopus)

  170 Downloads (Pure)

• A Model for (Quasi-)Periodic Multiwavelength Photometric Variability in Young Stellar Objects

  Kesseli, A. Y., Petkova, M. A., Wood, K., Whitney, B. A., Hillenbrand, L. A., Gregory, S. G., Stauffer, J. R., Morales-Calderon, M., Rebull, L. & Alencar, S. H. P., Sep 2016, In: Astrophysical Journal. 828, 1, p. 1-15 15 p., 42.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • hot spot
  • young
  • light curve
  • accretion
  • stars
  8 Citations (Scopus)

  84 Downloads (Pure)

• A Model for Processing Illocutionary Structures and Argumentation in Debates

  Budzynska, K., Janier, M., Reed, C., Saint-Dizier, P., Stede, M. & Yaskorska, O., 2014, LREC 2014 Proceedings. Calzolari, N., Choukri, K., Declerck, T., Loftsson, H., Maegaard, B., Mariani, J., Moreno, A., Odijk, J. & Piperidis, S. (eds.). European Language Resources Association, p. 917-924 8 p.

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  Open Access

  File
  15 Citations (Scopus)

  136 Downloads (Pure)

• A model for the energy bands of an "open"-type periodic structure: A periodic viaduct coupled with the half-space

  Lu, J-F., Li, J-H. & Jeng, D-S., 1 Feb 2012, In: Acta Mechanica. 223, 2, p. 257-277 21 p.

  Research output: Contribution to journal › Article › peer-review

  • Band structure
  • Periodic structures
  • Transfer matrix method
  • Piers
  • Acoustic impedance
  1 Citation (Scopus)

• A Model Sheet Mineral System to Study Fungal Bioweathering of Mica

  Wei, Z., Kierans, M. & Gadd, G. M., 2012, In: Geomicrobiology Journal. 29, 4, p. 323-331 9 p.

  Research output: Contribution to journal › Article › peer-review
  21 Citations (Scopus)

• A modest proposal

  Collison, D., 2012, In: CA Magazine. May, p. 62-63 2 p.

  Research output: Contribution to journal › Article › peer-review

• A Modified AUGIS Delphi Process to Establish Future Research Priorities in Benign Upper Gastrointestinal Surgery

  Wilson, M. S. J., Vaughan-Shaw, P., Boyle, C., Yong, G. L., Oglesby, S., Skipworth, R., Lamb, P., Griffiths, E. A. T. & Attwood, S. E. A., Apr 2020, In: World Journal of Surgery. 44, p. 1216-1222 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Consensus
  • Surgeons
  • Barrett Esophagus
  • Ireland
  • Pancreatitis
  2 Citations (Scopus)

• A modified Delphi process to establish future research priorities in malignant oesophagogastric surgery

  Wilson, M. S. J., Blencowe, N. S., Boyle, C., Knight, S. R., Petty, R., Vohra, R. S. & Underwood, T. J., 16 Dec 2019, In: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland. 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Neoplasms
  • Consensus
  • Surgeons
  • Ireland
  • Genomics
  2 Citations (Scopus)

• A modular platform for argument and dialogue

  Snaith, M., Lawrence, J., Pease, A. & Reed, C., 2020, Computational Models of Argument: Proceedings of COMMA 2020. Prakken, H., Bistarelli, S., Santini, F. & Taticchi, C. (eds.). Amsterdam, p. 473-474 2 p. (Frontiers in Artificial Intelligence and Applications; vol. 326).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

  Open Access

  File
  43 Downloads (Pure)

• A Modular Tray Growth System for Barley

  Arrieta, M., Colas, I., Macaulay, M., Waugh, R. & Ramsay, L., 2020, Plant Meiosis: Methods and Protocols. Pradillo, M. & Heckmann, S. (eds.). New York: Humana Press, p. 367-379 13 p. (Methods in Molecular Biology; vol. 2061).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

  Open Access

  File

  • Hordeum
  • Meiosis
  • Growth
  • Physiological Stress
  • Genetic Recombination
  1 Citation (Scopus)

  28 Downloads (Pure)

• Amoebozoa

  Schilde, C., Aug 2019, Encyclopedia of Microbiology. Schmidt, T. (ed.). 4 ed. United Kingdom: Academic Press, Vol. 1. p. 99-106 8 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review

  • Amoebozoa
  • fruiting bodies
  • eukaryotic cells
  • taxonomy
  • Entamoeba

• A molecular method to assess Phytophthora diversity in environmental samples

  Scibetta, S., Schena, L., Chimento, A., Cacciola, S. O. & Cooke, D. E. L., Mar 2012, In: Journal of Microbiological Methods. 88, 3, p. 356-368 13 p.

  Research output: Contribution to journal › Article › peer-review
  60 Citations (Scopus)

• A molecular switch driving inactivation in the cardiac K channel hERG

  Köpfer, D. A., Hahn, U., Ohmert, I., Vriend, G., Pongs, O., de Groot, B. L. & Zachariae, U., 24 Jul 2012, In: PLoS ONE. 7, 7, e41023.

  Research output: Contribution to journal › Article › peer-review

  • Hydrogen bonds
  • Hydrogen
  • Action Potentials
  • inactivation
  • selectivity (chemistry)
  14 Citations (Scopus)

• A More Scientific Approach to Applied Economics: Reconstructing Statistical, Analytical Significance, and Correlation Analysis

  Altman, M., 28 Feb 2019, In: SSRN Working Paper Series. 23 p.

  Research output: Contribution to journal › Article

  • statistical significance
  • economics
  • causality
  • persistence
  • literature

• "A Morning Since Eight of Just Pure Grill": A Multischool Qualitative Study of Student Abuse

  Rees, C. E. & Monrouxe, L. V., Nov 2011, In: Academic Medicine: Journal of the Association of American Medical Colleges. 86, 11, p. 1374-1382 9 p.

  Research output: Contribution to journal › Article › peer-review
  46 Citations (Scopus)

• A motion simulation and biomechanical analysis of the shoulder joint using a whole human model

  Sen, S., Abboud, R., Wang, W., Ming, D., Wan, B., Liao, Y. & Gong, Q., 1 Jan 2011, Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011. Ding, Y., Peng, Y., Shi, R., Hao, K. & Wang, L. (eds.). IEEE Computer Society, Vol. 4. p. 2322-2326 5 p.

  Research output: Chapter in Book/Report/Conference proceeding › Other chapter contribution

  • Torque
  • Biomechanics
  • Sports
  • Animation
  • Animals
  4 Citations (Scopus)

• A mouse model for functional dissection of TAB1 O-GlcNAcylation

  Authier, F., Muha, V. & van Aalten, D. M. F., 27 Aug 2019, In: Wellcome Open Research. 4, 16 p., 128.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Dissection
  • Carrier Proteins
  • Phosphotransferases
  • Phenotype
  • Medical problems
  15 Downloads (Pure)

• A moving interface finite element formulation for layered structures

  Funari, M. F., Greco, F. & Lonetti, P., 1 Jul 2016, In: Composites Part B: Engineering. 96, p. 325-337 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Debonding
  • Crack propagation
  • Composite materials
  34 Citations (Scopus)

• A moving interface finite element formulation to predict dynamic edge debonding in FRP-strengthened concrete beams in service conditions

  Funari, M. F., Spadea, S., Fabbrocino, F. & Luciano, R., Jun 2020, In: Fibers. 8, 6, p. 1-9 9 p., 42.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Debonding
  • Polymers
  • Fibers
  • Concretes
  • Crack initiation
  5 Citations (Scopus)

  212 Downloads (Pure)

• AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function

  Hardie, D. G., 15 Sep 2011, In: Genes & Development. 25, 18, p. 1895-1908 14 p.

  Research output: Contribution to journal › Review article › peer-review
  968 Citations (Scopus)

• AMP-activated protein kinase: a cellular energy sensor with a key role in metabolic disorders and in cancer

  Hardie, D. G., Feb 2011, In: Biochemical Society Transactions. 39, p. 1-13 13 p.

  Research output: Contribution to journal › Article › peer-review
  124 Citations (Scopus)

• AMP-activated protein kinase: also regulated by ADP?

  Hardie, D. G., Carling, D. & Gamblin, S. J., Sep 2011, In: Trends in Biochemical Sciences. 36, 9, p. 470-477 8 p.

  Research output: Contribution to journal › Review article › peer-review
  123 Citations (Scopus)

• AMP-activated protein kinase: a key regulator of energy balance with many roles in human disease

  Hardie, D. G., Dec 2014, In: Journal of Internal Medicine. 276, 6, p. 543-559 17 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Salicylates
  • Metformin
  • Aspirin
  • Adenosine Triphosphate
  159 Citations (Scopus)

  166 Downloads (Pure)

• AMP-activated protein kinase: a cellular energy sensor that comes in twelve flavours

  Ross, F. A., MacKintosh, C. & Hardie, D. G., 24 Mar 2016, In: FEBS Journal. 283, 16, p. 2987-3001 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Flavors
  • AMP-Activated Protein Kinases
  • Protein Isoforms
  • Gene encoding
  • Tumors
  138 Citations (Scopus)

  114 Downloads (Pure)

• AMP-Activated Protein Kinase: Friend or Foe in Cancer

  Vara-ciruelos, D., Dandapani, M. & Hardie, D. G., 4 Mar 2020, In: Annual Review of Cancer Biology. 4, p. 1-16 16 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Neoplasms
  • T-Cell Lymphoma
  • Carcinogenesis
  • Protein Kinase Inhibitors
  3 Citations (Scopus)

  41 Downloads (Pure)

• AMP-Activated Protein Kinase: Maintaining Energy Homeostasis at the Cellular and Whole-Body Levels

  Hardie, D. G., Jul 2014, In: Annual Review of Nutrition. 34, p. 31-55 25 p.

  Research output: Contribution to journal › Review article › peer-review

  • AMP-Activated Protein Kinases
  • Adenosine Monophosphate
  • Protein Kinases
  • Adenosine Triphosphate
  • Homeostasis
  120 Citations (Scopus)

• AMP-Activated Protein Kinase: A Target for Drugs both Ancient and Modern

  Hardie, D. G., Ross, F. A. & Hawley, S. A., 26 Oct 2012, In: Chemistry & Biology. 19, 10, p. 1222-36 15 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Cyclic AMP-Dependent Protein Kinases
  • Metformin
  • Adenosine Triphosphate
  • Medical problems
  252 Citations (Scopus)

  171 Downloads (Pure)

• AMP-Activated Protein Kinase: Do We Need Activators or Inhibitors to Treat or Prevent Cancer?

  Russell, F. M. & Hardie, D. G., 27 Dec 2020, In: International Journal of Molecular Sciences. 22, 1, 30 p., 186.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • adenosine monophosphate
  • AMP-Activated Protein Kinases
  • inhibitors
  • cancer
  • Proteins
  57 Downloads (Pure)

• AMP-activated protein kinase, a tumor suppressor that opposes the metabolic changes in cancer cells

  Hardie, D. G., Jun 2011, In: FEBS Journal. 278, s1, p. 41-42 2 p.

  Research output: Contribution to journal › Book/Film/Article review › peer-review

• AMP-activated protein kinase inhibits K_v1.5 channel currents of pulmonary arterial myocytes in response to hypoxia and inhibition of mitochondrial oxidative phosphorylation

  Moral-Sanz, J., Mahmoud, A. D., Ross, F. A., Eldstrom, J., Fedida, D., Hardie, D. G. & Evans, A. M., 1 Sep 2016, In: Journal of Physiology. 594, 17, p. 4901-4915 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Oxidative Phosphorylation
  • Muscle Cells
  • Hypoxia
  • Lung
  16 Citations (Scopus)

  162 Downloads (Pure)

• AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study

  Boyle, J. G., Logan, P. J., Jones, G. C., Small, M., Sattar, N., Connell, J. M. C., Cleland, S. J. & Salt, I. P., 2011, In: Diabetologia. 54, 7, p. 1799-1809 11 p.

  Research output: Contribution to journal › Article › peer-review
  54 Citations (Scopus)

• AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase

  Bultot, L., Guigas, B., Von Wilamowitz-Moellendorff, A., Maisin, L., Vertommen, D., Hussain, N., Beullens, M., Guinovart, J. J., Foretz, M., Viollet, B., Sakamoto, K., Hue, L. & Rider, M. H., 1 Apr 2012, In: Biochemical Journal. 443, p. 193-203 11 p.

  Research output: Contribution to journal › Article › peer-review
  59 Citations (Scopus)

• Amphiphilic oxygenated amorphous carbon-graphite buckypapers with gas sensitivity to polar and non-polar VOCs

  Homaeigohar, S., Sep 2019, In: Nanomaterials. 9, 9, p. 1-14 14 p., 1343.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Amorphous carbon
  • Volatile Organic Compounds
  • Graphite
  • Volatile organic compounds
  • Gases
  3 Citations (Scopus)

  21 Downloads (Pure)

• AMPK: regulating energy balance at the cellular and whole body levels

  Hardie, D. G. & Ashford, M. L. J., Mar 2014, In: Physiology. 29, 2, p. 99-107 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Adenine Nucleotides
  • AMP-Activated Protein Kinases
  • Eukaryota
  • Energy Intake
  • Energy Metabolism
  162 Citations (Scopus)

  166 Downloads (Pure)

• AMPK: a cellular energy sensor primarily regulated by AMP

  Gowans, G. J. & Hardie, D. G., 1 Feb 2014, In: Biochemical Society Transactions. 42, 1, p. 71-75 5 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Adenosine Monophosphate
  • Adenosine Diphosphate
  • Adenosine Triphosphate
  • Sensors
  77 Citations (Scopus)

  171 Downloads (Pure)

• AMPK: an energy-sensing pathway with multiple inputs and outputs

  Hardie, D. G., Schaffer, B. E. & Brunet, A., Mar 2016, In: Trends in Cell Biology. 26, 3, p. 190-201 12 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Adenosine Monophosphate
  • Adenosine Triphosphate
  • Phosphotransferases
  • Phosphorylation
  374 Citations (Scopus)

  357 Downloads (Pure)

• AMPK: a nutrient and energy sensor that maintains energy homeostasis

  Hardie, D. G., Ross, F. A. & Hawley, S. A., 1 Apr 2012, In: Nature Reviews Molecular Cell Biology. 13, 4, p. 251-262 12 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Nutrients
  • Adenosine Triphosphate
  • Homeostasis
  • Biosynthetic Pathways
  2210 Citations (Scopus)

  242 Downloads (Pure)

• AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1-Parkin independent manner

  Seabright, A. P., Fine, N. H. F., Barlow, J. P., Lord, S. O., Musa, I., Gray, A., Bryant, J. A., Banzhaf, M., Lavery, G. G., Hardie, D. G., Hodson, D. J., Philp, A. & Lai, Y-C., 4 May 2020, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 34, 5, p. 6284-6301 18 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Mitochondrial Degradation
  • Mitochondrial Dynamics
  • Adenosine Monophosphate
  • Protein Kinases
  • Chemical activation
  4 Citations (Scopus)

  81 Downloads (Pure)

• AMPK activators inhibit the proliferation of human melanomas bearing the activated MAPK pathway

  Petti, C., Vegetti, C., Molla, A., Bersani, I., Cleris, L., Mustard, K. J., Formelli, F., Hardie, G. D., Sensi, M. & Anichini, A., 2012, In: Melanoma Research. 22, 5, p. 341-350 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Melanoma
  • acadesine
  • 4-aminoimidazole
  • Phenformin
  • Mitogen-Activated Protein Kinase Kinases
  34 Citations (Scopus)

• AMPK and autophagy get connected

  Hardie, D. G., 16 Feb 2011, In: EMBO Journal. 30, 4, p. 634-635 2 p.

  Research output: Contribution to journal › Editorial › peer-review
  123 Citations (Scopus)

• AMPK and the Need to Breathe and Feed: What's the Matter with Oxygen?

  Evans, A. M. & Hardie, D. G., 15 May 2020, In: International Journal of Molecular Sciences. 21, 10, p. 1-28 28 p., 3518.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • adenosine monophosphate
  • AMP-Activated Protein Kinases
  • Oxygen supply
  • Proteins
  • Oxygen
  29 Downloads (Pure)

• AMPK and TOR: the Yin and Yang of cellular nutrient sensing and growth control

  González, A., Hall, M. N., Lin, S-C. & Hardie, G., 3 Mar 2020, In: Cell Metabolism. 31, 3, p. 472-492 21 p.

  Research output: Contribution to journal › Review article › peer-review

  • Yin-Yang
  • AMP-Activated Protein Kinases
  • Sirolimus
  • Nutrients
  • Growth
  29 Citations (Scopus)

• AMPK antagonizes hepatic glucagon-stimulated cyclic AMP signalling via phosphorylation-induced activation of cyclic nucleotide phosphodiesterase 4B

  Johanns, M., Lai, Y. C., Hsu, M. F., Jacobs, R., Vertommen, D., Van Sande, J., Dumont, J. E., Woods, A., Carling, D., Hue, L., Viollet, B., Foretz, M. & Rider, M. H., 8 Mar 2016, In: Nature Communications. 7, 10856.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • cyclic AMP
  • Phosphorylation
  • adenosine monophosphate
  • Type 4 Cyclic Nucleotide Phosphodiesterase
  • phosphorylation
  58 Citations (Scopus)

• AMPK as a direct sensor of long-chain fatty acyl–CoA esters

  Hardie, D. G., 27 Jul 2020, In: Nature Metabolism. 2, 9, p. 799-800 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Esters
  • Starvation
  • Ligands
  • Glucose
  4 Citations (Scopus)

  11 Downloads (Pure)

• AMPK Causes Cell Cycle Arrest in LKB1-deficient Cells via Activation of CAMKK2

  Fogarty, S., Ross, F. A., Vara Ciruelos, D., Gray, A., Gowans, G. J. & Hardie, D. G., 1 Aug 2016, In: Molecular Cancer Research. 14, 8, p. 683-695 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Cell Cycle Checkpoints
  • Null Lymphocytes
  • Calcimycin
  • Phosphorylation
  34 Citations (Scopus)

  318 Downloads (Pure)