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A molecular switch driving inactivation in the cardiac K channel hERG
Köpfer, D. A., Hahn, U., Ohmert, I., Vriend, G., Pongs, O., de Groot, B. L. & Zachariae, U., 24 Jul 2012, In: PLoS ONE. 7, 7, e41023.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
"A Morning Since Eight of Just Pure Grill": A Multischool Qualitative Study of Student Abuse
Rees, C. E. & Monrouxe, L. V., Nov 2011, In: Academic Medicine: Journal of the Association of American Medical Colleges. 86, 11, p. 1374-1382 9 p.Research output: Contribution to journal › Article › peer-review
46 Citations (Scopus) -
A Morphological identification cell cytotoxicity assay using cytoplasm-localized fluorescent probe (CLFP) to distinguish living and dead cells
Lai, F., Shen, Z., Wen, H., Chen, J., Zhang, X., Lin, P., Yin, D., Cui, H. & Chen, X., 8 Jan 2017, In: Biochemical and Biophysical Research Communications. 482, 2, p. 257-263 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)413 Downloads (Pure) -
A motion simulation and biomechanical analysis of the shoulder joint using a whole human model
Sen, S., Abboud, R., Wang, W., Ming, D., Wan, B., Liao, Y. & Gong, Q., 1 Jan 2011, Proceedings - 2011 4th International Conference on Biomedical Engineering and Informatics, BMEI 2011. Ding, Y., Peng, Y., Shi, R., Hao, K. & Wang, L. (eds.). IEEE Computer Society, Vol. 4. p. 2322-2326 5 p.Research output: Chapter in Book/Report/Conference proceeding › Other chapter contribution
4 Citations (Scopus) -
AMP-activated protein kinase: also regulated by ADP?
Hardie, D. G., Carling, D. & Gamblin, S. J., Sep 2011, In: Trends in Biochemical Sciences. 36, 9, p. 470-477 8 p.Research output: Contribution to journal › Review article › peer-review
123 Citations (Scopus) -
AMP-activated protein kinase: a cellular energy sensor with a key role in metabolic disorders and in cancer
Hardie, D. G., Feb 2011, In: Biochemical Society Transactions. 39, p. 1-13 13 p.Research output: Contribution to journal › Article › peer-review
124 Citations (Scopus) -
AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function
Hardie, D. G., 15 Sep 2011, In: Genes & Development. 25, 18, p. 1895-1908 14 p.Research output: Contribution to journal › Review article › peer-review
968 Citations (Scopus) -
AMP-Activated Protein Kinase: A Target for Drugs both Ancient and Modern
Hardie, D. G., Ross, F. A. & Hawley, S. A., 26 Oct 2012, In: Chemistry & Biology. 19, 10, p. 1222-36 15 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile252 Citations (Scopus)171 Downloads (Pure) -
AMP-Activated Protein Kinase: An Ubiquitous Signaling Pathway With Key Roles in the Cardiovascular System
Salt, I. P. & Hardie, D. G., 26 May 2017, In: Circulation Research. 120, 11, p. 1825-1841 17 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile77 Citations (Scopus)131 Downloads (Pure) -
AMP-activated protein kinase, a tumor suppressor that opposes the metabolic changes in cancer cells
Hardie, D. G., Jun 2011, In: FEBS Journal. 278, s1, p. 41-42 2 p.Research output: Contribution to journal › Book/Film/Article review › peer-review
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AMP-activated protein kinase activator A-769662 increases intracellular calcium and ATP release from astrocytes in an AMPK-independent manner
Vlachaki Walker, J. M., Robb, J. L., Cruz, A. M., Malhi, A., Weightman Potter, P. G., Ashford, M. L. J., McCrimmon, R. J., Ellacott, K. L. J. & Beall, C., 21 Apr 2017, In: Diabetes, Obesity & Metabolism. 19, 7, p. 997-1005 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)296 Downloads (Pure) -
AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study
Boyle, J. G., Logan, P. J., Jones, G. C., Small, M., Sattar, N., Connell, J. M. C., Cleland, S. J. & Salt, I. P., 2011, In: Diabetologia. 54, 7, p. 1799-1809 11 p.Research output: Contribution to journal › Article › peer-review
54 Citations (Scopus) -
AMP-activated protein kinase - not just an energy sensor
Hardie, D. G. & Lin, S-C., 22 Sep 2017, In: F1000 Research. 6, p. 1-11 11 p., 1724.Research output: Contribution to journal › Review article › peer-review
Open AccessFile47 Citations (Scopus)192 Downloads (Pure) -
AMP-activated protein kinase phosphorylates and inactivates liver glycogen synthase
Bultot, L., Guigas, B., Von Wilamowitz-Moellendorff, A., Maisin, L., Vertommen, D., Hussain, N., Beullens, M., Guinovart, J. J., Foretz, M., Viollet, B., Sakamoto, K., Hue, L. & Rider, M. H., 1 Apr 2012, In: Biochemical Journal. 443, p. 193-203 11 p.Research output: Contribution to journal › Article › peer-review
59 Citations (Scopus) -
AMPK: positive and negative regulation, and its role in whole-body energy homeostasis
Hardie, D. G., Apr 2015, In: Current Opinion in Cell Biology. 33, April, p. 1-7 7 p.Research output: Contribution to journal › Review article › peer-review
273 Citations (Scopus) -
AMPK: a nutrient and energy sensor that maintains energy homeostasis
Hardie, D. G., Ross, F. A. & Hawley, S. A., 1 Apr 2012, In: Nature Reviews Molecular Cell Biology. 13, 4, p. 251-262 12 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile2210 Citations (Scopus)243 Downloads (Pure) -
AMPK activators inhibit the proliferation of human melanomas bearing the activated MAPK pathway
Petti, C., Vegetti, C., Molla, A., Bersani, I., Cleris, L., Mustard, K. J., Formelli, F., Hardie, G. D., Sensi, M. & Anichini, A., 2012, In: Melanoma Research. 22, 5, p. 341-350 10 p.Research output: Contribution to journal › Article › peer-review
34 Citations (Scopus) -
AMPK and autophagy get connected
Hardie, D. G., 16 Feb 2011, In: EMBO Journal. 30, 4, p. 634-635 2 p.Research output: Contribution to journal › Editorial › peer-review
123 Citations (Scopus) -
AMPK dilates resistance arteries via activation of SERCA and BKCa channels in smooth muscle
Schneider, H., Schubert, K. M., Blodow, S., Kreutz, C-P., Erdogmus, S., Wiedenmann, M., Qiu, J., Fey, T., Ruth, P., Lubomirov, L. T., Pfitzer, G., Mederos y Schnitzler, M., Hardie, D. G., Gudermann, T. & Pohl, U., Jul 2015, In: Hypertension. 66, 1, p. 108-116 9 p.Research output: Contribution to journal › Article › peer-review
30 Citations (Scopus) -
AMPK promotes p53 acetylation via phosphorylation and inactivation of SIRT1 in liver cancer cells
Lee, C-W., Wong, L. L-Y., Tse, E. Y-T., Liu, H-F., Leong, V. Y-L., Lee, J. M-F., Hardie, D. G., Ng, I. O-L. & Ching, Y-P., 2012, In: Cancer Research. 72, 17, p. 4394-4404 11 p.Research output: Contribution to journal › Article › peer-review
132 Citations (Scopus) -
A MRI investigation of electroconvulsive therapy (ECT) for the treatment of depression
Perrin, J. S., Bennett, D. M., Currie, J., Steele, J. D. & Reid, I. C., Aug 2011, In: Journal of Psychopharmacology. 25, 8, p. A54-A54 1 p.Research output: Contribution to journal › Book/Film/Article review › peer-review
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A multi-centre, parallel group superiority trial of silk therapeutic clothing compared to standard care for the management of eczema in children (CLOTHES Trial): study protocol for a randomised controlled trial
Harrison, E. F., Haines, R. H., Cowdell, F., Sach, T. H., Dean, T., Pollock, I., Burrows, N. P., Buckley, H., Batchelor, J., Williams, H. C., Lawton, S., Brown, S. J., Bradshaw, L. E., Ahmed, A., Montgomery, A. A., Mitchell, E. J. & Thomas, K. S., 2 Sep 2015, In: Trials. 16, 12 p., 390.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)175 Downloads (Pure) -
A Multifunctional Protease Inhibitor To Regulate Endolysosomal Function
van Kasteren, S. I., Berlin, I., Colbert, J. D., Keane, D., Ovaa, H. & Watts, C., Nov 2011, In: ACS Chemical Biology. 6, 11, p. 1198-1204 7 p.Research output: Contribution to journal › Article › peer-review
16 Citations (Scopus) -
A multigenic model to predict risk of ischemic stroke in subjects with type 2 diabetes
Pola, R., Kimber, C. H., Giarretta, I., Doney, A., Morris, A. M., Gaetani, E. & Palmer, C. N., Jun 2011, In: Atherosclerosis. Supplements. 12, 1, p. 127-127 1 p.Research output: Contribution to journal › Article › peer-review
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A multiprotein binding interface in an intrinsically disordered region of the tumor suppressor protein interferon regulatory factor-1
Narayan, V., Halada, P., Hernychová, L., Chong, Y. P., Žáková, J., Hupp, T. R., Vojtesek, B. & Ball, K. L., 22 Apr 2011, In: Journal of Biological Chemistry. 286, 16, p. 14291-14303 13 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
A multi-repeat adhesin of the phytopathogen, Pectobacterium atrosepticum, is secreted by a Type I pathway and is subject to complex regulation involving a non-canonical diguanylate cyclase
Perez-Mendoza, D., Coulthurst, S. J., Humphris, S., Campbell, E., Welch, M., Toth, I. K. & Salmond, G. P. C., Nov 2011, In: Molecular Microbiology. 82, 3, p. 719-733 15 p.Research output: Contribution to journal › Article › peer-review
43 Citations (Scopus) -
A multiscale approach for evaluating the failure condition of calcarenite structures subject to environmental loads
Ciantia, M. O., Castellanza, R., Fernandez Merodo, J. A. & Hueckel, T., 2015, Geomechanics from Micro to Macro - Proceedings of the TC105 ISSMGE International Symposium on Geomechanics from Micro to Macro, IS-Cambridge 2014. Taylor & Francis, Vol. 2. p. 939-944 6 p.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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A multiscale approach to curvature modulated sorting in biological membranes
Mercker, M., Ptashnyk, M., Kuhnle, J., Hartmann, D., Weiss, M. & Jager, W., May 2012, In: Journal of Theoretical Biology. 301, 5, p. 67-82 16 p.Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus) -
A multiscale mathematical model of tumour invasive growth
Peng, L., Trucu, D., Lin, P., Thompson, A. & Chaplain, M. A. J., Mar 2017, In: Bulletin of Mathematical Biology. 79, 3, p. 389-429 41 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Citations (Scopus)178 Downloads (Pure) -
A multi-sensor approach to continuous monitoring of a glacier outflow channel: Virkisá River, SE Iceland
Black, A., Everest, J., MacDonald, A., Flett, V., Buxel, H. & Shanahan, T., 26 Jun 2015. 1 p.Research output: Contribution to conference › Abstract › peer-review
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A multispectral endoscope based on spectrally resolved detector arrays
Luthman, S., Waterhouse, D., Bollepalli, L., Joseph, J. & Bohndiek, S., 28 Jul 2017, Clinical and Preclinical Optical Diagnostics. Brown, J. Q. & van Leeuwen, T. G. (eds.). Society of Photo-optical Instrumentation Engineers, 3 p. 104110A. (Proceedings of SPIE; vol. 10411).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
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A Multi-task Deep Network for Person Re-identification
Chen, W., Chen, X., Zhang, J. & Huang, K., 17 Feb 2017, Proceedings of The Thirty-First AAAI Conference on Artificial Intelligence (AAAI-17). Singh, S. & Markovitch, S. (eds.). Palo Alto, CA: AAAI Press, p. 3988-3994 7 p.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
Open AccessFile107 Citations (Scopus)116 Downloads (Pure) -
A multi-wavelength (u.v. to visible) laser system for early detection of oral cancer
Najda, S. P., Perlin, P., Leszczynski, M., Slight, T. J., Meredith, W., Schemmann, M., Moseley, H., Woods, J. A., Valentine, R., Kalra, S., Mossey, P., Theaker, E., Macluskey, M., Mimnagh, G. & Mimnagh, W., 2015, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XIII. Farkas, D. L., Nicolau, D. V. & Leif, R. C. (eds.). Bellingham: SPIE-International Society for Optical Engineering, Vol. 9328. 932809. (Proceedings of SPIE; vol. 9328)(Progress in biomedical optics and imaging; vol. 16, no. 26).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
7 Citations (Scopus) -
A mutant O-GlcNAcase as a probe to reveal global dynamics of protein O-GlcNAcylation during Drosophila embryonic development
Mariappa, D., Selvan, N., Borodkin, V. S., Alonso, J., Ferenbach, A. T., Shepherd, C., Navratilova, I. H. & Van Aalten, D. M. F., Sep 2015, In: Biochemical Journal. 470, 2, p. 255-262 8 p.Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus) -
A mutant O-GlcNAcase enriches Drosophila developmental regulators
Selvan, N., Williamson, R., Mariappa, D., Campbell, D. G., Gourlay, R., Ferenbach, A. T., Aristotelous, T., Hopkins-Navratilova, I., Trost, M. & van Aalten, D. M. F., Aug 2017, In: Nature Chemical Biology. 13, 8, p. 882-887 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Citations (Scopus)199 Downloads (Pure) -
Anabolic resistance does not explain sarcopenia in patients with type 2 diabetes mellitus, compared with healthy controls, despite reduced mTOR pathway activity
Cuthbertson, D. J., Babraj, J., Leese, G. & Siervo, M., Dec 2017, In: Clinical Nutrition. 36, 6, p. 1716-1719 4 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
An accuracy assessment of forensic computerized facial reconstruction employing cone-beam computed tomography from live subjects
Lee, W-J., Wilkinson, C. M. & Hwang, H-S., Mar 2012, In: Journal of Forensic Sciences. 57, 2, p. 318-327 10 p.Research output: Contribution to journal › Article › peer-review
53 Citations (Scopus) -
An adaptive IEEE 802.15.4 data transmission scheme for smart grid applications
Che, Z., He, J., Tang, Z., Zhou, Y. & Chen, K., 23 Dec 2011, U- and E-Service, Science and Technology - International Conference, UNESST 2011, Held as Part of the Future Generation Information Technology Conf., FGIT 2011, in Conjunction with GDC 2011, Proc.. Berlin, p. 93-99 7 p. (Communications in Computer and Information Science; vol. 264 CCIS).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
1 Citation (Scopus) -
An adaptive information technology for the operative diagnostics of the tropical cyclones: solar-terrestrial coupling mechanisms
Krapivin, V. F., Soldatov, V. Y., Varotsos, C. A. & Cracknell, A. P., 2012, In: Journal of Atmospheric and Solar-Terrestrial Physics. 89, p. 83-89 7 p.Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus) -
Anaesthesia for laryngo-tracheal surgery, including tubeless field techniques
Pearson, K. L. & McGuire, B. E., 1 Jul 2017, In: BJA Education. 17, 7, p. 242-248 7 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
Analgesic tone conferred by constitutively active mu opioid receptors in mice lacking beta-arrestin 2
Lam, H., Maga, M., Pradhan, A., Evans, C. J., Maidment, N. T., Hales, T. G. & Walwyn, W., 12 Apr 2011, In: Molecular Pain. 7, p. - 10 p., 24.Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus) -
An algorithm recommendation for the pharmacological management of allergic rhinitis in the UK: a consensus statement from an expert panel
Lipworth, B., Newton, J., Ram, B., Small, I. & Schwarze, J., 23 Jan 2017, In: NPJ Primary Care Respiratory Medicine. 27, p. 1-8 8 p., 3.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)175 Downloads (Pure) -
Analogs of the Natural Product Chamuvarinin Target the Trypanosomatid FoF1-ATP Synthase Mitochondrial Complex V
Menzies, S. K., Tulloch, L. B., Fraser, A. L., Gould, E. R., King, E. F., Zacharova, M. K., Florence, G. J. & Smith, T. K., 2017, In: American Journal of Tropical Medicine and Hygiene. 95, 5 Supplement, p. 164 1 p., 520.Research output: Contribution to journal › Meeting abstract › peer-review
5 Citations (Scopus) -
An alternate route to phosphorylating DegU of Bacillus subtilis using acetyl phosphate
Cairns, L. S., Martyn, J. E., Bromley, K. & Stanley-Wall, N. R., 31 Mar 2015, In: BMC Microbiology. 15, 12 p., 78.Research output: Contribution to journal › Article › peer-review
10 Citations (Scopus) -
Analysing time-related properties of service-oriented systems
Bocchi, L., Fiadeiro, J., Solanki, M., Gilmore, S., Abreu, J. & Vankayala, V., 1 Dec 2011, Handbook of Research on Service-Oriented Systems and Non-Functional Properties: Future Directions. IGI Global, p. 36-60 25 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Analysis and Approximation of Microstructure Models: preface to special issue
Muntean, A., Ptashnyk, M. & Showalter, R. E., 1 Jun 2012, In: Applicable Analysis. 91, 6, p. 1053-1054 2 p.Research output: Contribution to journal › Special issue
2 Citations (Scopus) -
Analysis for Time Discrete Approximations of Blow-up Solutions of Semilinear Parabolic Equations
Kyza, I. & Makridakis, C., 2011, In: SIAM Journal on Numerical Analysis. 49, 1, p. 405-426 22 p.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus) -
Analysis of > 1000 single nucleotide polymorphisms in geographically matched samples of landrace and wild barley indicates secondary contact and chromosome-level differences in diversity around domestication genes
Russell, J., Dawson, I. K., Flavell, A. J., Steffenson, B., Weltzien, E., Booth, A., Ceccarelli, S., Grando, S. & Waugh, R., 2011, In: New Phytologist. 191, 2, p. 564-578 15 p.Research output: Contribution to journal › Article › peer-review
56 Citations (Scopus) -
Analysis of bender element test interpretation using the discrete element method
O’Donovan, J., O’Sullivan, C., Marketos, G. & Muir Wood, D., Apr 2015, In: Granular Matter. 17, 2, p. 197-216 20 p.Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus) -
Analysis of Conformational Changes in the DNA Junction-Resolving Enzyme T7 Endonuclease I on Binding a Four-Way Junction Using EPR
Freeman, A. D. J., Ward, R., El Mkami, H., Lilley, D. M. J. & Norman, D. G., 22 Nov 2011, In: Biochemistry. 50, 46, p. 9963-9972 10 p.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus)