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  • Blair Smith
Article

Polygenic risk for alcohol dependence associates with alcohol consumption, cognitive function and social deprivation in a population-based cohort

Clarke, T-K., Smith, A. H., Gelernter, J., Kranzler, H. R., Farrer, L. A., Hall, L. S., Fernandez-Pujals, A. M., MacIntyre, D. J., Smith, B. H., Hocking, L. J., Padmanabhan, S., Hayward, C., Thomson, P. A., Porteous, D. J., Deary, I. J. & McIntosh, A. M., Mar 2016, In : Addiction Biology. 21, 2, p. 469-480 12 p.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
146 Downloads (Pure)

Potential pain management programmes in primary care: a UK-wide questionnaire and Delphi survey of experts

Torrance, N., Smith, B. H., Elliott, A. M., Campbell, S. E., Chambers, W. A., Hannaford, P. C. & Johnston, M., Feb 2011, In : Family Practice. 28, 1, p. 41-48 8 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

Mahajan, A., Wessel, J., Willems, S. M., Zhao, W., Robertson, N. R., Chu, A. Y., Gan, W., Kitajima, H., Taliun, D., Rayner, N. W., Guo, X., Lu, Y., Li, M., Jensen, R. A., Hu, Y., Huo, S., Lohman, K. K., Zhang, W., Cook, J. P., Prins, B. P. & 31 others, Flannick, J., Grarup, N., Trubetskoy, V. V., Kravic, J., Kim, Y. J., Rybin, D. V., Yaghootkar, H., Müller-Nurasyid, M., Meidtner, K., Li-Gao, R., Varga, T. V., Marten, J., Li, J., Smith, A. V., An, P., Ligthart, S., Gustafsson, S., Malerba, G., Demirkan, A., Tajes, J. F., Steinthorsdottir, V., Wuttke, M., Lecoeur, C., Preuss, M., Bielak, L. F., Graff, M., Highland, H. M., Morris, A. D., Smith, B. H., Palmer, C. N. A. & ExomeBP Consortium, 9 Apr 2018, In : Nature Genetics. 50, 4, p. 559-571 13 p.

Research output: Contribution to journalArticle

Open Access
File
82 Citations (Scopus)
254 Downloads (Pure)

Regional variation in health is predominantly driven by lifestyle rather than genetics

Amador, C., Xia, C., Nagy, R., Campbell, A., Porteous, D. J., Smith, B. H., Hastie, N., Vitart, V., Hayward, C., Navarro, P. & Haley, C. S., 6 Oct 2017, In : Nature Communications. 8, p. 1-7 7 p., 801.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
155 Downloads (Pure)

Sex-differences in the metabolic health of offspring of parents with diabetes: a record-linkage study

Aldhous, M. C., Reynolds, R. M., Campbell, A., Linksted, P., Lindsay, R. S., Smith, B. H., Seckl, J. R., Porteous, D. J., Norman, J. E. & Generation Scotland, 26 Aug 2015, In : PLoS ONE. 10, 8, 18 p., e0134883.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Shared genetics and couple-associated environment are major contributors to the risk of both clinical and self-declared depression

Yanni, Z., Navarro, P., Xia, C., Amador, C., Fernandez-Pujals, A. M., Thomson, P. A., Campbell, A., Nagy, R., Clarke, T-K., Hafferty, J. D., Smith, B., Hocking, L. J., Padmanabhan, S., Hayward, C., MacIntrye, D. J., Porteous, D. J., Haley, C. S. & McIntosh, A. M., Dec 2016, In : EBioMedicine. 14, p. 161-167 7 p.

Research output: Contribution to journalArticle

Open Access
File
17 Citations (Scopus)
129 Downloads (Pure)

Smoking-by-genotype interaction in type 2 diabetes risk and fasting glucose

Wu, P., Rybin, D., Bielak, L. F., Feitosa, M. F., Franceschini, N., Li, Y., Lu, Y., Marten, J., Musani, S. K., Noordam, R., Raghavan, S., Rose, L. M., Schwander, K., Smith, A. V., Tajuddin, S. M., Vojinovic, D., Amin, N., Arnett, D. K., Bottinger, E. P., Demirkan, A. & 38 others, Florez, J. C., Ghanbari, M., Harris, T. B., Launer, L. J., Liu, J., Liu, J., Mook-Kanamori, D. O., Murray, A. D., Nalls, M. A., Peyser, P. A., Uitterlinden, A. G., Voortman, T., Bouchard, C., Chasman, D., Correa, A., de Mutsert, R., Evans, M. K., Gudnason, V., Hayward, C., Kao, L., Kardia, S. L. R., Kooperberg, C., Loos, R. J. F., Province, M. M., Rankinen, T., Redline, S., Ridker, P. M., Rotter, J. I., Siscovick, D., Smith, B. H., van Duijn, C., Zonderman, A. B., Rao, D. C., Wilson, J. G., Dupuis, J., Meigs, J. B., Liu, C-T. & Vassy, J. L., 7 May 2020, In : PLoS ONE. 15, 5, p. 1-17 17 p., e0230815.

Research output: Contribution to journalArticle

Open Access
File
15 Downloads (Pure)

Stratification by Smoking Status Reveals an Association of CHRNA5-A3-B4 Genotype with Body Mass Index in Never Smokers

Taylor, A. E., Morris, R. W., Fluharty, M. E., Bjorngaard, J. H., Asvold, B. O., Gabrielsen, M. E., Campbell, A., Marioni, R., Kumari, M., Hällfors, J., Männistö, S., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Husemoen, L. L. N., Skaaby, T., Ahluwalia, T. S., Treur, J. L., Willemsen, G. & 44 others, Dale, C., Wannamethee, S. G., Lahti, J., Palotie, A., Räikkönen, K., Kisialiou, A., McConnachie, A., Padmanabhan, S., Wong, A., Dalgård, C., Paternoster, L., Ben-Shlomo, Y., Tyrrell, J., Horwood, J., Fergusson, D. M., Kennedy, M. A., Frayling, T., Nohr, E. A., Christiansen, L., Kyvik, K. O., Kuh, D., Watt, G., Eriksson, J., Whincup, P. H., Vink, J. M., Boomsma, D. I., Davey Smith, G., Lawlor, D., Linneberg, A., Ford, I., Jukema, J. W., Power, C., Hyppönen, E., Jarvelin, M-R., Preisig, M., Borodulin, K., Kaprio, J., Kivimaki, M., Smith, B. H., Hayward, C., Romundstad, P. R., Sørensen, T. I. A., Munafò, M. R. & Sattar, N., 4 Dec 2014, In : PLoS Genetics. 10, 12, 6 p., e1004799.

Research output: Contribution to journalArticle

Open Access
File
35 Citations (Scopus)
119 Downloads (Pure)
Open Access
File
3 Citations (Scopus)
80 Downloads (Pure)

Systematically searching for and assessing the literature for self-management of chronic pain: a lay users' perspective

Schofield, P., Smith, B. H., Martin, D., Jones, D., Clarke, A., McNamee, P., Marsh, R., Morrison, M., Morrison, R., Fowler, S., Anthony, G. & Stewart, C., 27 Jul 2014, In : BMC Geriatrics. 14, 1, 8 p., 86.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
123 Downloads (Pure)

Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease

Johnson, M. R., Shkura, K., Langley, S. R., Delahaye-Duriez, A., Srivastava, P., Hill, W. D., Rackham, O. J. L., Davies, G., Harris, S. E., Moreno-Moral, A., Rotival, M., Speed, D., Petrovski, S., Katz, A., Hayward, C., Porteous, D. J., Smith, B. H., Padmanabhan, S., Hocking, L. J., Starr, J. M. & 14 others, Liewald, D. C., Visconti, A., Falchi, M., Bottolo, L., Rossetti, T., Danis, B., Mazzuferi, M., Foerch, P., Grote, A., Helmstaedter, C., Becker, A. J., Kaminski, R. M., Deary, I. J. & Petretto, E., 1 Feb 2016, In : Nature Neuroscience. 19, 2, p. 223-232 10 p.

Research output: Contribution to journalArticle

Open Access
File
56 Citations (Scopus)
227 Downloads (Pure)

Targeted genetic testing for familial hypercholesterolaemia using next generation sequencing: a population-based study

Norsworthy, P. J., Vandrovcova, J., Thomas, E. R. A., Campbell, A., Kerr, S. M., Biggs, J., Game, L., Soutar, A. K., Smith, B. H., Dominiczak, A. F., Porteous, D. J., Morris, A. D., Generation Scotland & Aitman, T. J., 23 Jun 2014, In : BMC Medical Genetics. 15, 7 p., 70.

Research output: Contribution to journalArticle

Open Access
File
37 Citations (Scopus)
129 Downloads (Pure)

The Scottish model for chronic pain management services

Gilbert, S., Holdsworth, L. & Smith, B., 2014, In : British Journal of Healthcare Management. 20, 12, p. 568-577 10 p.

Research output: Contribution to journalArticle

Timing, rates and spectra of human germline mutation

Rahbari, R., Wuster, A., Lindsay, S. J., Hardwick, R. J., Alexandrov, L. B., Al Turki, S., Dominiczak, A., Morris, A., Porteous, D., Smith, B., Stratton, M. R., UK10K Consortium & Hurles, M. E., Feb 2016, In : Nature Genetics. 48, 2, p. 126-133

Research output: Contribution to journalArticle

Open Access
File
190 Citations (Scopus)
235 Downloads (Pure)

Training peers to support older people with chronic low back pain following physiotherapy discharge: a feasibility study

Cooper, K., Mary Jehu, L., Klein, S., Smith, B. H. & Schofield, P., Jun 2018, In : Physiotherapy. 104, 2, p. 239-247 9 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
231 Downloads (Pure)

Trends in gabapentinoid prescribing, co-prescribing of opioids and benzodiazepines, and associated deaths in Scotland

Torrance, N., Veluchamy, A., Zhou, Y., Fletcher, E., Moir, E., Hebert, H., Donnan, P., Watson, J., Colvin, L. & Smith, B. H., 19 Jun 2020, In : British Journal of Anaesthesia. 9 p.

Research output: Contribution to journalArticle

Using discrete choice experiments to inform randomised controlled trials: an application to chronic low back pain management in primary care

Yi, D., Ryan, M., Campbell, S., Elliott, A., Torrance, N., Chambers, A., Johnston, M., Hannaford, P. & Smith, B. H., May 2011, In : European Journal of Pain. 15, 5, p. - 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Variants associated with HHIP expression have sex-differential effects on lung function

Smith, B. H., 1 Jun 2020, In : Wellcome Open Research. 5, p. 1-14 14 p., 111.

Research output: Contribution to journalArticle

Open Access
File
4 Downloads (Pure)

World Health Organization essential medicines lists: where are the drugs to treat neuropathic pain?

Kamerman, P. R., Wadley, A. L., Davis, K. D., Hietaharju, A., Jain, P., Kopf, A., Meyer, A-C., Raja, S. N., Rice, A. S. C., Smith, B. H., Treede, R-D. & Wiffen, P. J., May 2015, In : Pain. 156, 5, p. 793-797 5 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
Book/Film/Article review

Pain and the global burden of disease

Rice, A. S. C., Smith, B. H. & Blyth, F. M., Apr 2016, In : Pain. 157, 4, p. 791-796 6 p.

Research output: Contribution to journalBook/Film/Article review

Open Access
File
75 Citations (Scopus)
328 Downloads (Pure)
Chapter

Neuropathic pain

Smith, B. H. & Torrance, N., 1 Jan 2011, Chronic Pain Epidemiology: From Aetiology to Public Health. Croft, P., Blyth, F. M. & van der Windt, D. (eds.). Oxford University Press

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

The effect of Stanford-type self-management programmes on pain and function in older people with persistent pain

Martin, D., Schofield, P., Jones, D., McNamee, P., Clarke, A., Anthony, G. & Smith, B., 1 Jan 2013, Pain: International Research in Pain Management. Nova Science Publishers, p. 165-172 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Comment/debate

Lessons from Mackenzie that still resonate

Van Hecke, O., Smith, B. H. & Sullivan, F. M., Mar 2013, In : British Journal of General Practice. 63, 608, p. 158-159 2 p.

Research output: Contribution to journalComment/debate

Out of Hours: My personal diagnostic delay

Smith, B. H., 1 Apr 2015, In : British Journal of General Practice. 65, 633, p. 200 1 p.

Research output: Contribution to journalComment/debate

Letter

Association of DISC1 variants with age of onset in a population-based sample of recurrent major depression

Thomson, P. A., MacIntyre, D. J., Hamilton, G., Dominiczak, A., Smith, B. H., Morris, A., Evans, K. L. & Porteous, D. J., Jul 2013, In : Molecular Psychiatry. 18, 7, p. 745-747 3 p.

Research output: Contribution to journalLetter

9 Citations (Scopus)

Exome-wide association study of plasma lipids in >300,000 individuals

Liu, D. J., Peloso, G. M., Yu, H., Butterworth, A. S., Wang, X-Y., Mahajan, A., Saleheen, D., Emdin, C., Alam, D. S., Alves, A. C., Amouyel, P., Di Angelantonio, E., Arveiler, D., Assimes, T. L., Auer, P. L., Baber, U., Ballantyne, C. M., Bang, L. E., Benn, M., Bis, J. C. & 31 others, Boehnke, M., Boerwinkle, E., Bork-Jensen, J., Bottinger, E. P., Brandslund, I., Brown, M. J., Busonero, F., Caulfield, M. J., Chambers, J. C., Chasman, D. I., Chen, Y. E., Chen, Y-D. I., Chowdhury, R., Christensen, C., Chu, A. Y., Connell, J. M., Cucca, F., Cupples, L. A., Damrauer, S. M., Davies, G., Deary, I. J., Dedoussis, G., Denny, J. C., Dominiczak, A. F., Dubé, M. P., Ebeling, T., Eiriksdottir, G., Esko, T., Palmer, C. N. A., Smith, B. H. & Charge Diabetes Working Group, The EPIC-InterAct Consortium, EPIC-CVD Consortium, GOLD Consortium, VA Million Veteran Program, 30 Oct 2017, In : Nature Genetics. 49, 12, p. 1758-1766 9 p.

Research output: Contribution to journalLetter

Open Access
File
147 Citations (Scopus)
117 Downloads (Pure)

Genome-wide association study identifies 74 loci associated with educational attainment

Okbay, A., Beauchamp, J. P., Fontana, M. A., Lee, J. J., Pers, T. H., Rietveld, C. A., Turley, P., Chen, G-B., Emilsson, V., Meddens, S. F. W., Oskarsson, S., Pickrell, J. K., Thom, K., Timshel, P., de Vlaming, R., Abdellaoui, A., Ahluwalia, T. S., Bacelis, J., Baumbach, C., Bjornsdottir, G. & 31 others, Brandsma, J. H., Pina Concas, M., Derringer, J., Furlotte, N. A., Galesloot, T. E., Girotto, G., Gupta, R., Hall, L. M., Harris, S. E., Hofer, E., Horikoshi, M., Huffman, J. E., Kaasik, K., Kalafati, I. P., Karlsson, R., Kong, A., Lahti, J., van der Lee, S. J., deLeeuw, C., Lind, P. A., Lindgren, K-O., Liu, T., Mangino, M., Marten, J., Mihailov, E., Miller, M. B., van der Most, P. J., Oldmeadow, C., Payton, A., Smith, B. H. & LifeLines Cohort Study, 26 May 2016, In : Nature. 533, 7604, p. 539-542 4 p.

Research output: Contribution to journalLetter

Open Access
File
444 Citations (Scopus)
97 Downloads (Pure)

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation

Christophersen, I. E., Rienstra, M., Roselli, C., Yin, X., Geelhoed, B., Barnard, J., Lin, H., Arking, D. E., Smith, A. V., Albert, C. M., Chaffin, M., Tucker, N. R., Li, M., Klarin, D., Bihlmeyer, N. A., Low, S-K., Weeke, P. E., Mueller-Nurasyid, M., Smith, J. G., Brody, J. A. & 142 others, Niemeijer, M. N., Doerr, M., Trompet, S., Huffman, J. E., Gustafsson, S., Schurmann, C., Kleber, M. E., Lyytikainen, L-P., Seppala, I., Malik, R., Horimoto, A. R. V. R., Perez, M., Sinisalo, J., Aeschbacher, S., Theriault, S., Yao, J., Radmanesh, F., Weiss, S., Teumer, A., Choi, S. H., Weng, L-C., Clauss, S., Deo, R., Rader, D. J., Shah, S. H., Sun, A., Hopewell, J. C., Debette, S., Chauhan, G., Yang, Q., Worrall, B. B., Pare, G., Kamatani, Y., Hagemeijer, Y. P., Verweij, N., Siland, J. E., Kubo, M., Smith, J. D., Van Wagoner, D. R., Bis, J. C., Perz, S., Psaty, B. M., Ridker, P. M., Magnani, J. W., Harris, T. B., Launer, L. J., Shoemaker, M. B., Padmanabhan, S., Haessler, J., Bartz, T. M., Waldenberger, M., Lichtner, P., Arendt, M., Krieger, J. E., Kahonen, M., Risch, L., Mansur, A. J., Peters, A., Smith, B. H., Lind, L., Scott, S. A., Lu, Y., Bottinger, E. B., Hernesniemi, J., Lindgren, C. M., Wong, J. A., Huang, J., Eskola, M., Morris, A. P., Ford, I., Reiner, A. P., Delgado, G., Chen, L. Y., Chen, Y-D. I., Sandhu, R. K., Li, M., Boerwinkle, E., Eisele, L., Lannfelt, L., Rost, N., Anderson, C. D., Taylor, K. D., Campbell, A., Magnusson, P. K. E., Porteous, D. J., Hocking, L. J., Vlachopoulou, E., Pedersen, N. L., Nikus, K., Orho-Melander, M., Hamsten, A., Heeringa, J., Denny, J. C., Kriebel, J., Darbar, D., Newton-Cheh, C., Shaffer, C. M., Macfarlane, P. W., Heilmann-Heimbach, S., Almgren, P., Huang, P. L., Sotoodehnia, N., Soliman, E. Z., Uitterlinden, A. G., Hofman, A., Franco, O. H., Voelker, U., Joeckel, K-H., Sinner, M. F., Lin, H. J., Guo, X., Dichgans, M., Ingelsson, E., Kooperberg, C., Melander, O., Loos, R. J. F., Laurikka, J., Conen, D., Rosand, J., van der Harst, P., Lokki, M-L., Kathiresan, S., Pereira, A., Jukema, J. W., Hayward, C., Rotter, J. I., Maerz, W., Lehtimaki, T., Stricker, B. H. C., Chung, M. K., Felix, S. B., Gudnason, V., Alonso, A., Roden, D. M., Kaeaeb, S., Chasman, D. I., Heckbert, S. R., Benjamin, E. J., Tanaka, T., Lunetta, K. L., Lubitz, S. A. & Ellinor, P. T., Jun 2017, In : Nature Genetics. 49, 6, p. 946-952 7 p.

Research output: Contribution to journalLetter

Open Access
File
105 Citations (Scopus)
250 Downloads (Pure)

Large-scale discovery of novel genetic causes of developmental disorders

Deciphering Developmental Disorders (DDD) Study, 12 Mar 2015, In : Nature. 519, 7542, p. 223-228 6 p.

Research output: Contribution to journalLetter

457 Citations (Scopus)
Meeting abstract

Predictors of QTc and QTc prolongation in the Generation Scotland Family Study

Brown, C. E., Hastie, C. E., Alghamdi, J., Schulz, C., Hocking, L. J., Luciano, M., Porteous, D., Morris, A., Smith, B. H., Dominiczak, A. F., Tobias, E. S., Delles, C. & Padmanabhan, S., 2013, In : Journal of Human Hypertension. 27, 10, p. 639-639 1 p.

Research output: Contribution to journalMeeting abstract

Review article

Chronic pain in later life: A review of current issues and challenges

Schofield, P., Clarke, A., Jones, D., Martin, D., McNamee, P. & Smith, B., Aug 2011, In : Aging Health. 7, 4, p. 551-556 6 p.

Research output: Contribution to journalReview article

16 Citations (Scopus)
Open Access
File
23 Citations (Scopus)
141 Downloads (Pure)

Investigating shared aetiology between type 2 diabetes and major depressive disorder in a population based cohort

Clarke, T-K., Obsteter, J., Hall, L. S., Hayward, C., Thomson, P. A., Smith, B. H., Padmanabhan, S., Hocking, L. J., Deary, I. J., Porteous, D. J. & McIntosh, A. M., Apr 2017, In : American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 174, 3, p. 227-234 8 p.

Research output: Contribution to journalReview article

Open Access
File
11 Citations (Scopus)
151 Downloads (Pure)

NeuPSIG guidelines on neuropathic pain assessment

Haanpaa, M., Attal, N., Backonja, M., Baron, R., Bennett, M., Bouhassira, D., Cruccu, G., Hansson, P., Haythornthwaite, J. A., Iannetti, G. D., Jensen, T. S., Kauppila, T., Nurmikko, T. J., Rice, A. S. C., Rowbotham, M., Serra, J., Sommer, C., Smith, B. H. & Treede, R-D., Jan 2011, In : Pain. 152, 1, p. 14-27 14 p.

Research output: Contribution to journalReview article

622 Citations (Scopus)

Physical activity and exercise for chronic pain in adults: an overview of Cochrane Reviews

Geneen, L. J., Moore, R. A., Clarke, C., Martin, D., Colvin, L. A. & Smith, B. H., 14 Jan 2017, In : Cochrane Database of Systematic Reviews. 2017, 4, p. 1-75 75 p., CD011279.

Research output: Contribution to journalReview article

Open Access
File
5 Citations (Scopus)
211 Downloads (Pure)

Physical activity and exercise for chronic pain in adults: an overview of Cochrane Reviews

Geneen, L. J., Moore, R. A., Clarke, C., Martin, D., Colvin, L. A. & Smith, B. H., 24 Apr 2017, In : Cochrane Database of Systematic Reviews. 2017, 4, p. 1-75 75 p., CD011279.

Research output: Contribution to journalReview article

Open Access
File
17 Citations (Scopus)
156 Downloads (Pure)

Risk factors for neuropathic pain in diabetes mellitus

Hébert, H. L., Veluchamy, A., Torrance, N. & Smith, B. H., 1 Apr 2017, In : Pain. 158, 4, p. 560-568 9 p.

Research output: Contribution to journalReview article

Open Access
File
21 Citations (Scopus)
189 Downloads (Pure)

Systematic review and meta-analysis of genetic risk factors for neuropathic pain

Veluchamy, A., Hébert, H. L., Meng, W., Palmer, C. N. A. & Smith, B. H., May 2018, In : Pain. 159, 5, p. 825-848 24 p.

Research output: Contribution to journalReview article

Open Access
File
13 Citations (Scopus)
250 Downloads (Pure)

The effect of stanford-type self-management programmes on pain and function in older people with persistent pain: A systematic review of randomised controlled trials

Martin, D., Schofield, P., Jones, D., McNamee, P., Clarke, A., Anthony, G. & Smith, B., 8 Oct 2013, In : Journal of Pain Management. 6, 2, p. 117-122 6 p.

Research output: Contribution to journalReview article

2 Citations (Scopus)

Translating clinical trials into improved real-world management of pain: Convergence of translational, population-based and primary care research

Gilron, I., Blyth, F. M. & Smith, B., Jan 2020, In : Pain. 161, 1, p. 36-42 7 p.

Research output: Contribution to journalReview article