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  • Blair Smith
2019

A catalog of genetic loci associated with kidney function from analyses of a million individuals

LifeLines Cohort Study, Wuttke, M., Li, Y., Li, M., Sieber, K. B., Feitosa, M. F., Gorski, M., Tin, A., Wang, L., Chu, A. Y., Hoppmann, A., Kirsten, H., Giri, A., Chai, J-F., Sveinbjornsson, G., Tayo, B. O., Nutile, T., Fuchsberger, C., Marten, J., Cocca, M. & 33 others, Ghasemi, S., Xu, Y., Horn, K., Noce, D., van der Most, P. J., Sedaghat, S., Yu, Z., Akiyama, M., Afaq, S., Ahluwalia, T. S., Almgren, P., Amin, N., Ärnlöv, J., Bakker, S. J. L., Bansal, N., Baptista, D., Bergmann, S., Biggs, M. L., Biino, G., Boehnke, M., Boerwinkle, E., Boissel, M., Bottinger, E. P., Boutin, T. S., Brenner, H., Brumat, M., Burkhardt, R., Butterworth, A. S., Campana, E., Campbell, A., Smith, B. H., Köttgen, A. & Pattaro, C., Jun 2019, In : Nature Genetics. 51, 6, p. 957-972 16 p.

Research output: Contribution to journalArticle

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39 Citations (Scopus)
108 Downloads (Pure)

A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure

LifeLines Cohort Study, Sung, Y. J., de Las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., Manning, A. K., Brown, M. R., Aschard, H., Feitosa, M. F., Franceschini, N., Lu, Y., Cheng, C-Y., Sim, X., Vojinovic, D. & 40 others, Marten, J., Musani, S. K., Kilpeläinen, T. O., Richard, M. A., Aslibekyan, S., Bartz, T. M., Dorajoo, R., Li, C., Liu, Y., Rankinen, T., Smith, A. V., Tajuddin, S. M., Tayo, B. O., Zhao, W., Zhou, Y., Matoba, N., Sofer, T., Alver, M., Amini, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Giulianini, F., Goel, A., Harris, S. E., Hartwig, F. P., Connell, J. M., Smith, B. H., Rotter, J. I., Franks, P. W., Rice, K., Elliott, P., Caulfield, M. J., Gauderman, W. J., Munroe, P. B., Rao, D. C. & Morrison, A. C., 1 Aug 2019, In : Human Molecular Genetics. 28, 15, p. 2615-2633 19 p.

Research output: Contribution to journalArticle

Open Access
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4 Citations (Scopus)
24 Downloads (Pure)

Associations of autozygosity with a broad range of human phenotypes

Clark, D. W., Okada, Y., Moore, K. H. S., Mason, D., Pirastu, N., Gandin, I., Mattsson, H., Barnes, C. L. K., Lin, K., Zhao, J. H., Deelen, P., Rohde, R., Schurmann, C., Guo, X., Giulianini, F., Zhang, W., Medina-Gomez, C., Karlsson, R., Bao, Y., Bartz, T. M. & 416 others, Baumbach, C., Biino, G., Bixley, M. J., Brumat, M., Chai, J-F., Corre, T., Cousminer, D. L., Dekker, A. M., Eccles, D. A., van Eijk, K. R., Fuchsberger, C., Gao, H., Germain, M., Gordon, S. D., de Haan, H. G., Harris, S. E., Hofer, E., Huerta-Chagoya, A., Igartua, C., Jansen, I. E., Jia, Y., Kacprowski, T., Karlsson, T., Kleber, M. E., Li, S. A., Li-Gao, R., Mahajan, A., Matsuda, K., Meidtner, K., Meng, W., Montasser, M. E., van der Most, P. J., Munz, M., Nutile, T., Palviainen, T., Prasad, G., Prasad, R. B., Priyanka, T. D. S., Rizzi, F., Salvi, E., Sapkota, B. R., Shriner, D., Skotte, L., Smart, M. C., Smith, A. V., van der Spek, A., Spracklen, C. N., Strawbridge, R. J., Tajuddin, S. M., Trompet, S., Turman, C., Verweij, N., Viberti, C., Wang, L., Warren, H. R., Wootton, R. E., Yanek, L. R., Yao, J., Yousri, N. A., Zhao, W., Adeyemo, A. A., Afaq, S., Aguilar-Salinas, C. A., Akiyama, M., Albert, M. L., Allison, M. A., Alver, M., Aung, T., Azizi, F., Bentley, A. R., Boeing, H., Boerwinkle, E., Borja, J. B., de Borst, G. J., Bottinger, E. P., Broer, L., Campbell, H., Chanock, S., Chee, M-L., Chen, G., Chen, Y-D. I., Chen, Z., Chiu, Y-F., Cocca, M., Collins, F. S., Concas, M. P., Corley, J., Cugliari, G., van Dam, R. M., Damulina, A., Daneshpour, M. S., Day, F. R., Delgado, G. E., Dhana, K., Doney, A. S. F., Dörr, M., Doumatey, A. P., Dzimiri, N., Ebenesersdóttir, S. S., Elliott, J., Elliott, P., Ewert, R., Felix, J. F., Fischer, K., Freedman, B. I., Girotto, G., Goel, A., Gögele, M., Goodarzi, M. O., Graff, M., Granot-Hershkovitz, E., Grodstein, F., Guarrera, S., Gudbjartsson, D. F., Guity, K., Gunnarsson, B., Guo, Y., Hagenaars, S. P., Haiman, C. A., Halevy, A., Harris, T. B., Hedayati, M., van Heel, D. A., Hirata, M., Höfer, I., Hsiung, C. A., Huang, J., Hung, Y-J., Ikram, M. A., Jagadeesan, A., Jousilahti, P., Kamatani, Y., Kanai, M., Kerrison, N. D., Kessler, T., Khaw, K-T., Khor, C. C., de Kleijn, D. P. V., Koh, W-P., Kolcic, I., Kraft, P., Krämer, B. K., Kutalik, Z., Kuusisto, J., Langenberg, C., Launer, L. J., Lawlor, D. A., Lee, I-T., Lee, W-J., Lerch, M. M., Li, L., Liu, J., Loh, M., London, S. J., Loomis, S., Lu, Y., Luan, J., Mägi, R., Manichaikul, A. W., Manunta, P., Másson, G., Matoba, N., Mei, X. W., Meisinger, C., Meitinger, T., Mezzavilla, M., Milani, L., Millwood, I. Y., Momozawa, Y., Moore, A., Morange, P-E., Moreno-Macías, H., Mori, T. A., Morrison, A. C., Muka, T., Murakami, Y., Murray, A. D., de Mutsert, R., Mychaleckyj, J. C., Nalls, M. A., Nauck, M., Neville, M. J., Nolte, I. M., Ong, K. K., Orozco, L., Padmanabhan, S., Pálsson, G., Pankow, J. S., Pattaro, C., Pattie, A., Polasek, O., Poulter, N., Pramstaller, P. P., Quintana-Murci, L., Räikkönen, K., Ralhan, S., Rao, D. C., van Rheenen, W., Rich, S. S., Ridker, P. M., Rietveld, C. A., Robino, A., van Rooij, F. J. A., Ruggiero, D., Saba, Y., Sabanayagam, C., Sabater-Lleal, M., Sala, C. F., Salomaa, V., Sandow, K., Schmidt, H., Scott, L. J., Scott, W. R., Sedaghati-Khayat, B., Sennblad, B., van Setten, J., Sever, P. J., Sheu, W. H-H., Shi, Y., Shrestha, S., Shukla, S. R., Sigurdsson, J. K., Sikka, T. T., Singh, J. R., Smith, B. H., Stančáková, A., Stanton, A., Starr, J. M., Stefansdottir, L., Straker, L., Sulem, P., Sveinbjornsson, G., Swertz, M. A., Taylor, A. M., Taylor, K. D., Terzikhan, N., Tham, Y-C., Thorleifsson, G., Thorsteinsdottir, U., Tillander, A., Tracy, R. P., Tusié-Luna, T., Tzoulaki, I., Vaccargiu, S., Vangipurapu, J., Veldink, J. H., Vitart, V., Völker, U., Vuoksimaa, E., Wakil, S. M., Waldenberger, M., Wander, G. S., Wang, Y. X., Wareham, N. J., Wild, S., Yajnik, C. S., Yuan, J-M., Zeng, L., Zhang, L., Zhou, J., Amin, N., Asselbergs, F. W., Bakker, S. J. L., Becker, D. M., Lehne, B., Bennett, D. A., van den Berg, L. H., Berndt, S. I., Bharadwaj, D., Bielak, L. F., Bochud, M., Boehnke, M., Bouchard, C., Bradfield, J. P., Brody, J. A., Campbell, A., Carmi, S., Caulfield, M. J., Cesarini, D., Chambers, J. C., Chandak, G. R., Cheng, C-Y., Ciullo, M., Cornelis, M., Cusi, D., Smith, G. D., Deary, I. J., Dorajoo, R., van Duijn, C. M., Ellinghaus, D., Erdmann, J., Eriksson, J. G., Evangelou, E., Evans, M. K., Faul, J. D., Feenstra, B., Feitosa, M., Foisy, S., Franke, A., Friedlander, Y., Gasparini, P., Gieger, C., Gonzalez, C., Goyette, P., Grant, S. F. A., Griffiths, L. R., Groop, L., Gudnason, V., Gyllensten, U., Hakonarson, H., Hamsten, A., van der Harst, P., Heng, C-K., Hicks, A. A., Hochner, H., Huikuri, H., Hunt, S. C., Jaddoe, V. W. V., De Jager, P. L., Johannesson, M., Johansson, Å., Jonas, J. B., Jukema, J. W., Junttila, J., Kaprio, J., Kardia, S. L. R., Karpe, F., Kumari, M., Laakso, M., van der Laan, S. W., Lahti, J., Laudes, M., Lea, R. A., Lieb, W., Lumley, T., Martin, N. G., März, W., Matullo, G., McCarthy, M. I., Medland, S. E., Merriman, T. R., Metspalu, A., Meyer, B. F., Mohlke, K. L., Montgomery, G. W., Mook-Kanamori, D., Munroe, P. B., North, K. E., Nyholt, D. R., O'connell, J. R., Ober, C., Oldehinkel, A. J., Palmas, W., Palmer, C., Pasterkamp, G. G., Patin, E., Pennell, C. E., Perusse, L., Peyser, P. A., Pirastu, M., Polderman, T. J. C., Porteous, D. J., Posthuma, D., Psaty, B. M., Rioux, J. D., Rivadeneira, F., Rotimi, C., Rotter, J. I., Rudan, I., Den Ruijter, H. M., Sanghera, D. K., Sattar, N., Schmidt, R., Schulze, M. B., Schunkert, H., Scott, R. A., Shuldiner, A. R., Sim, X., Small, N., Smith, J. A., Sotoodehnia, N., Tai, E-S., Teumer, A., Timpson, N. J., Toniolo, D., Tregouet, D-A., Tuomi, T., Vollenweider, P., Wang, C. A., Weir, D. R., Whitfield, J. B., Wijmenga, C., Wong, T-Y., Wright, J., Yang, J., Yu, L., Zemel, B. S., Zonderman, A. B., Perola, M., Magnusson, P. K. E., Uitterlinden, A. G., Kooner, J. S., Chasman, D. I., Loos, R. J. F., Franceschini, N., Franke, L., Haley, C. S., Hayward, C., Walters, R. G., Perry, J. R. B., Esko, T., Helgason, A., Stefansson, K., Joshi, P. K., Kubo, M. & Wilson, J. F., 31 Oct 2019, In : Nature Communications. 10, 1, p. 1-17 17 p., 4957.

Research output: Contribution to journalArticle

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3 Citations (Scopus)
67 Downloads (Pure)

Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

Understanding Society Scientific Group, Shrine, N., Guyatt, A. L., Erzurumluoglu, A. M., Jackson, V. E., Hobbs, B. D., Melbourne, C. A., Batini, C., Fawcett, K. A., Song, K., Sakornsakolpat, P., Li, X., Boxall, R., Reeve, N. F., Obeidat, M., Zhao, J. H., Wielscher, M., Weiss, S., Kentistou, K. A., Cook, J. P. & 33 others, Sun, B. B., Zhou, J., Hui, J., Karrasch, S., Imboden, M., Harris, S. E., Marten, J., Enroth, S., Kerr, S. M., Surakka, I., Vitart, V., Lehtimäki, T., Allen, R. J., Bakke, P. S., Beaty, T. H., Bleecker, E. R., Bossé, Y., Brandsma, C-A., Chen, Z., Crapo, J. D., Danesh, J., DeMeo, D. L., Dudbridge, F., Ewert, R., Gieger, C., Gulsvik, A., Hansell, A. L., Hao, K., Hoffman, J. D., Hokanson, J. E., Smith, B. H., Tobin, M. D. & Wain, L. V., Jun 2019, In : Nature Genetics. 51, 6, p. 1067 1 p.

Research output: Contribution to journalArticle

Open Access
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18 Citations (Scopus)
7 Downloads (Pure)

Chronic pain as a symptom or a disease: the IASP Classification of Chronic Pain for the International Classification of Diseases (ICD-11)

Treede, R-D., Rief, W., Barke, A., Aziz, Q., Bennett, M. I., Benoliel, R., Cohen, M., Evers, S., Finnerup, N. B., First, M. B., Giamberardino, M. A., Kaasa, S., Korwisi, B., Kosek, E., Lavandʼhomme, P., Nicholas, M., Perrot, S., Scholz, J., Schug, S., Smith, B. H. & 3 others, Svensson, P., Vlaeyen, J. W. S. & Wang, S-J., 1 Jan 2019, In : Pain. 160, 1, p. 19-27 9 p.

Research output: Contribution to journalReview article

Open Access
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113 Citations (Scopus)
558 Downloads (Pure)
Open Access
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1 Citation (Scopus)
2 Downloads (Pure)
Open Access
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3 Citations (Scopus)
139 Downloads (Pure)
Open Access
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1 Citation (Scopus)
58 Downloads (Pure)

Genetic and shared couple environmental contributions to smoking and alcohol use in the UK population

Clarke, T-K., Adams, M. J., Howard, D. M., Xia, C., Davies, G., Hayward, C., Campbell, A., Padmanabhan, S., Smith, B., Murray, A., Porteous, D., Deary, I. J. & McIntosh, A. M., 25 Nov 2019, In : Molecular Psychiatry. 11 p.

Research output: Contribution to journalArticle

Open Access
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Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations

Understanding Society Scientific Group, Sakornsakolpat, P., Prokopenko, D., Lamontagne, M., Reeve, N. F., Guyatt, A. L., Jackson, V. E., Shrine, N., Qiao, D., Bartz, T. M., Kim, D. K., Lee, M. K., Latourelle, J. C., Li, X., Morrow, J. D., Obeidat, M., Wyss, A. B., Bakke, P., Barr, R. G., Beaty, T. H. & 35 others, Belinsky, S. A., Brusselle, G. G., Crapo, J. D., de Jong, K., DeMeo, D. L., Fingerlin, T. E., Gharib, S. A., Gulsvik, A., Hall, I. P., Hokanson, J. E., Kim, W. J., Lomas, D. A., London, S. J., Meyers, D. A., O’Connor, G. T., Rennard, S. I., Schwartz, D. A., Sliwinski, P., Sparrow, D., Strachan, D. P., Tal-Singer, R., Tesfaigzi, Y., Vestbo, J., Vonk, J. M., Yim, J. J., Zhou, X., Bossé, Y., Manichaikul, A., Lahousse, L., Silverman, E. K., Boezen, H. M., Wain, L. V., Tobin, M. D., Hobbs, B. D. & Cho, M. H., 1 Mar 2019, In : Nature Genetics. 51, 3, p. 494-505 12 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

23andMe Research Team, Karlsson Linnér, R., Biroli, P., Kong, E., Meddens, S. F. W., Wedow, R., Fontana, M. A., Lebreton, M., Tino, S. P., Abdellaoui, A., Hammerschlag, A. R., Nivard, M. G., Okbay, A., Rietveld, C. A., Timshel, P. N., Trzaskowski, M., Vlaming, R. D., Zünd, C. L., Bao, Y., Buzdugan, L. & 22 others, Caplin, A. H., Chen, C. Y., Eibich, P., Fontanillas, P., Gonzalez, J. R., Joshi, P. K., Karhunen, V., Kleinman, A., Levin, R. Z., Lill, C. M., Meddens, G. A., Muntané, G., Sanchez-Roige, S., Rooij, F. J. V., Taskesen, E., Wu, Y., Zhang, F., Auton, A., Boardman, J. D., Clark, D. W., Conlin, A. & Beauchamp, J. P., 2019, In : Nature Genetics. 51, 2, p. 245-257 13 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)

Genome-wide association study of knee pain identifies associations with GDF5 and COL27A1 in UK Biobank

Meng, W., Adams, M. J., Palmer, C. N. A., 23andMe Research Team, Shi, J., Auton, A., Ryan, K. A., Jordan, J. M., Mitchell, B. D., Jackson, R. D., Yau, M. S., McIntosh, A. M. & Smith, B. H., 28 Aug 2019, In : Communications Biology. 2, p. 1-8 8 p., 321.

Research output: Contribution to journalArticle

Open Access
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2 Citations (Scopus)
88 Downloads (Pure)

Implementation of Patient-Reported Outcomes (PROMs) from specialist pain clinics in England and Wales: experience from a nationwide study

Price, C. M., C. de C. Williams, A., Smith, B. H. & Bottle, A., 1 Aug 2019, In : European Journal of Pain. 23, 7, p. 1368-1377 10 p.

Research output: Contribution to journalArticle

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Insulin resistance: Genetic associations with depression and cognition in population based cohorts

Frangou, S., Shirali, M., Adams, M. J., Howard, D. M., Gibson, J., Hall, L. S., Smith, B. H., Padmanabhan, S., Murray, A. D., Porteous, D. J., Haley, C. S., Deary, I. J., Clarke, T-K. & McIntosh, A. M., Jun 2019, In : Experimental Neurology. 316, p. 20-26 7 p.

Research output: Contribution to journalArticle

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1 Citation (Scopus)
104 Downloads (Pure)

Low-frequency variation in TP53 has large effects on head circumference and intracranial volume

UK10K Consortium, 21 Jan 2019, In : Nature Communications. 10, 1, 357.

Research output: Contribution to journalArticle

Open Access
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5 Citations (Scopus)
70 Downloads (Pure)

Multiancestry Genome-Wide Association Study of Lipid Levels Incorporating Gene-Alcohol Interactions

InterAct Consortium, LifeLines Cohort Study, de Vries, P. S., Brown, M. R., Bentley, A. R., Sung, Y. J., Winkler, T. W., Ntalla, I., Schwander, K., Kraja, A. T., Guo, X., Franceschini, N., Cheng, C-Y., Sim, X., Vojinovic, D., Huffman, J. E., Musani, S. K., Li, C., Feitosa, M. F., Richard, M. A. & 34 others, Noordam, R., Aschard, H., Bartz, T. M., Bielak, L. F., Deng, X., Dorajoo, R., Lohman, K. K., Manning, A. K., Rankinen, T., Smith, A. V., Tajuddin, S. M., Evangelou, E., Graff, M., Alver, M., Boissel, M., Chai, J. F., Chen, X., Divers, J., Gandin, I., Gao, C., Goel, A., Hagemeijer, Y., Harris, S. E., Hartwig, F. P., He, M., Horimoto, A. R. V. R., Hsu, F-C., Jackson, A. U., Kasturiratne, A., Komulainen, P., Connell, J. M., Smith, B. H., Rao, D. C. & Morrison, A. C., 1 Jun 2019, In : American Journal of Epidemiology. 188, 6, p. 1033-1054 22 p.

Research output: Contribution to journalArticle

Open Access
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12 Citations (Scopus)
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New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries

Understanding Society Scientific Group, Shrine, N., Guyatt, A. L., Erzurumluoglu, A. M., Jackson, V. E., Hobbs, B. D., Melbourne, C. A., Batini, C., Fawcett, K. A., Song, K., Sakornsakolpat, P., Li, X., Boxall, R., Reeve, N. F., Obeidat, M., Zhao, J. H., Wielscher, M., Weiss, S., Kentistou, K. A., Cook, J. P. & 33 others, Sun, B. B., Zhou, J., Hui, J., Karrasch, S., Imboden, M., Harris, S. E., Marten, J., Enroth, S., Kerr, S. M., Surakka, I., Vitart, V., Lehtimäki, T., Allen, R. J., Bakke, P. S., Beaty, T. H., Bleecker, E. R., Bossé, Y., Brandsma, C-A., Chen, Z., Crapo, J. D., Danesh, J., DeMeo, D. L., Dudbridge, F., Ewert, R., Gieger, C., Gulsvik, A., Hansell, A. L., Hao, K., Hoffman, J. D., Hokanson, J. E., Smith, B. H., Tobin, M. D. & Wain, L. V., Mar 2019, In : Nature Genetics. 51, 3, p. 481-493 13 p.

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30 Citations (Scopus)
213 Downloads (Pure)

Opioid prescribing is rising in many countries

Smith, B. H., Fletcher, E. H. & Colvin, L. A., 17 Oct 2019, In : BMJ. 367, p. 1-2 2 p., l5823.

Research output: Contribution to journalEditorial

4 Citations (Scopus)

PALS: peer support for community dwelling older people with chronic low back pain: a feasibility and acceptability study

Cooper, K., Schofield, P., Smith, B. H. & Klein, S., 4 Feb 2019, In : Physiotherapy (United Kingdom). 9 p.

Research output: Contribution to journalArticle

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2 Citations (Scopus)
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Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

T2D-Genes Consortium, The MAGIC Investigators, CHD Exome+ Consortium, EPIC-CVD Consortium, ExomeBP Consortium, Global Lipids Genetic Consortium, GoT2D Genes Consortium, ReproGen Consortium, Justice, A. E., Karaderi, T., Highland, H. M., Young, K. L., Graff, M., Lu, Y., Turcot, V., Auer, P. L., Fine, R. S., Guo, X., Schurmann, C., Lempradl, A. & 40 others, Marouli, E., Mahajan, A., Winkler, T. W., Locke, A. E., Medina-Gomez, C., Esko, T., Vedantam, S., Giri, A., Lo, K. S., Alfred, T., Mudgal, P., Ng, M. C. Y., Heard-Costa, N. L., Feitosa, M. F., Manning, A. K., Willems, S. M., Sivapalaratnam, S., Abecasis, G., Alam, D. S., Allison, M., Amouyel, P., Arzumanyan, Z., Balkau, B., Bastarache, L., Bergmann, S., Bielak, L. F., Blüher, M., Boehnke, M., Boeing, H., Boerwinkle, E., Böger, C. A., Bork-Jensen, J., Evangelou, E., Li, J., Morris, A. P., Smith, B. H., Smith, J. A., Wood, A. R., North, K. E. & Lindgren, C. M., Mar 2019, In : Nature Genetics. 51, 3, p. 452-469 18 p.

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18 Citations (Scopus)
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Reply to Henningsen et al.

Rief, W., Korwisi, B., Nicholas, M., Vlaeyen, J. W. S., Smith, B. H., First, M. B., Kosek, E., Barke, A. & Treede, R-D., Jul 2019, In : Pain. 160, 7, p. 1683-1685 3 p.

Research output: Contribution to journalLetter

Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels

Tin, A., Marten, J., Halperin Kuhns, V. L., Li, Y., Wuttke, M., Kirsten, H., Sieber, K. B., Qiu, C., Gorski, M., Yu, Z., Giri, A., Sveinbjornsson, G., Li, M., Chu, A. Y., Hoppmann, A., O'Connor, L. J., Prins, B., Nutile, T., Noce, D., Akiyama, M. & 31 others, Cocca, M., Ghasemi, S., van der Most, P. J., Horn, K., Xu, Y., Fuchsberger, C., Sedaghat, S., Afaq, S., Amin, N., Ärnlöv, J., Bakker, S. J. L., Bansal, N., Baptista, D., Bergmann, S., Biggs, M. L., Biino, G., Boerwinkle, E., Bottinger, E. P., Boutin, T. S., Brumat, M., Burkhardt, R., Campana, E., Campbell, A., Campbell, H., Carroll, R. J., Catamo, E., Chambers, J. C., Ciullo, M., Concas, M. P., Smith, B. H. & Köttgen, A., Oct 2019, In : Nature Genetics. 51, 10, p. 1459–1474 22 p.

Research output: Contribution to journalArticle

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14 Citations (Scopus)
13 Downloads (Pure)

The genetics of neuropathic pain from model organisms to clinical application

Calvo, M., Davies, A. J., Hebert, H., Weir, G., Chesler, E. J., Finnerup, N. B., Smith, B. H., Neely, G., Costigan, M. & Bennett, D. L., 20 Nov 2019, In : Neuron. 104, 4, p. 637-653 17 p.

Research output: Contribution to journalReview article

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2 Citations (Scopus)
56 Downloads (Pure)

The IASP classification of chronic pain for ICD-11: Applicability in Primary Care

Smith, B., Fors, E. A., Korwisi, B., Barke, A., Cameron, P., Colvin, L., Richardson, C., Rief, W. & Treede, R-D., 1 Jan 2019, In : Pain. 160, 1, p. 83-87 5 p.

Research output: Contribution to journalReview article

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14 Citations (Scopus)
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The IASP classification of chronic pain for ICD-11: Chronic neuropathic pain

Scholz, J., Finnerup, N. B., Attal, N., Aziz, Q., Baron, R., Bennett, M. I., Benoliel, R., Cohen, M., Cruccu, G., Davis, K. D., Evers, S., First, M. B., Giamberardino, M. A., Hansson, P. T., Kaasa, S., Korwisi, B., Kosek, E., Lavandʼhomme, P., Nicholas, M., Nurmikko, T. J. & 13 others, Perrot, S., Raja, S. N., Rice, A. S. C., Rowbotham, M. C., Schug, S., Smipson, D. M., Smith, B., Svensson, P., Vlaeyen, J. W. S., Wang, S-J., Barke, A., Rief, W. & Treede, R-D., 1 Jan 2019, In : Pain. 160, 1, p. 53-59 7 p.

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38 Citations (Scopus)
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The National Pain Audit for specialist pain services in England and Wales 2010–2014

Price, C., de C Williams, A. C., Smith, B. H. & Bottle, A., 1 Aug 2019, In : British Journal of Pain. 13, 3, p. 185-193 9 p.

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2016

An empirical comparison of joint and stratified frameworks for studying G x E interactions: systolic blood pressure and smoking in the CHARGE gene-lifestyle interactions working group

Sung, Y. J., Winkler, T. W., Manning, A. K., Aschard, H., Gudnason, V., Harris, T. B., Smith, A. V., Boerwinkle, E., Brown, M. R., Morrison, A. C., Fornage, M., Lin, L. A., Richard, M., Bartz, T. M., Psaty, B. M., Hayward, C., Polasek, O., Marten, J., Rudan, I., Feitosa, M. F. & 38 others, Kraja, A. T., Province, M. A., Deng, X., Fisher, V. A., Zhou, Y., Bielak, L. F., Smith, J., Huffman, J. E., Padmanabhan, S., Smith, B. H., Ding, J., Liu, Y., Lohman, K., Bouchard, C., Rankinen, T., Rice, T. K., Arnett, D., Schwander, K., Guo, X., Palmas, W., Rotter, J. I., Alfred, T., Bottinger, E. P., Loos, R. J. F., Amin, N., Franco, O. H., van Duijn, C. M., Vojinovic, D., Chasman, D. I., Ridker, P. M., Rose, L. M., Kardia, S., Zhu, X., Rice, K., Borecki, I. B., Rao, D. C., Gauderman, W. J. & Cupples, L. A., Jul 2016, In : Genetic Epidemiology. 40, 5, p. 404-415 12 p.

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9 Citations (Scopus)
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An epidemiological study of neuropathic pain symptoms in Canadian adults

VanDenKerkhof, E. G., Mann, E. G., Torrance, N., Smith, B. H., Johnson, A. & Gilron, I., 2016, In : Pain Research and Management. 2016, p. 1-13 13 p., 9815750.

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Association of Forced Vital Capacity with the Developmental Gene NCOR2

Minelli, C., Dean, C. H., Hind, M., Alves, A. C., Amaral, A. F. S., Siroux, V., Huikari, V., Artigas, M. S., Evans, D. M., Loth, D. W., Bossé, Y., Postma, D. S., Sin, D., Thompson, J., Demenais, F., Henderson, J., Bouzigon, E., Jarvis, D., Järvelin, M. R., Burney, P. & 155 others, Gharib, S. A., Wain, L. V., Franceschini, N., Koch, B., Pottinger, T. D., Smith, A. V., Duan, Q., Oldmeadow, C., Lee, M. K., Strachan, D. P., James, A. L., Huffman, J. E., Vitart, V., Ramasamy, A., Wareham, N. J., Kaprio, J., Wang, X. Q., Trochet, H., Kähönen, M., Flexeder, C., Albrecht, E., Lopez, L. M., De Jong, K., Thyagarajan, B., Enroth, S., Omenaas, E., Joshi, P. K., Fall, T., Viñuela, A., Launer, L. J., Loehr, L. R., Fornage, M., Li, G., Wilk, J. B., Tang, W., Manichaikul, A., Lahousse, L., Harris, T. B., North, K. E., Rudnicka, A. R., Hui, J., Gu, X., Lumley, T., Wright, A. F., Hastie, N. D., Campbell, S., Kumar, R., Pin, I., Scott, R. A., Pietiläinen, K. H., Surakka, I., Liu, Y., Holliday, E. G., Schulz, H., Heinrich, J., Davies, G., MVonk, J., Wojczynski, M., Pouta, A., Johansson, Å., Wild, S. H., Ingelsson, E., Rivadeneira, F., Völzke, H., Hysi, P. G., Eiriksdottir, G., Morrison, A. C., Rotter, J. I., Gao, W., White, W. B., Rich, S. S., Hofman, A., Aspelund, T., Couper, D., Smith, L. J., Psaty, B. M., Lohman, K., Burchard, E. G., Uitterlinden, A. G., Garcia, M., Joubert, B. R., McArdle, W. L., Musk, A. B., Hansel, N., Heckbert, S. R., Zgaga, L., Van Meurs, J. B. J., Navarro, P., Rudan, I., Oh, Y. M., Redline, S., Jarvis, D. L., Zhao, J. H., Rantanen, T., O Connor, G. T., Ripatti, S., Scott, R. J., Karrasch, S., Grallert, H., Gaddis, N. C., MStarr, J., Wijmenga, C., Minster, R. L., Lederer, D. J., Pekkanen, J., Gyllensten, U., Campbell, H., Morris, A. P., Gläser, S., Hammond, C. J., MBurkart, K., Beilby, J., Kritchevsky, S. B., Gudnason, V., Hancock, D. B., Williams, OD., Polasek, O., Zemunik, T., Kolcic, I., Petrini, M. F., Wjst, M., Kim, W. J., Porteous, D. J., Scotland, G., Smith, B. H., Viljanen, A., Heliövaara, M., Attia, J. R., Sayers, I., Hampel, R., Gieger, C., Deary, I. J., Boezen, H. M., Newman, A., Wilson, J. F., Lind, L., Stricker, B. H., Teumer, A., Spector, T. D., Melén, E., Peters, M. J., Lange, L. A., Barr, R. G., Bracke, K. R., MVerhamme, F., Sung, J., Hiemstra, P. S., Cassano, P. A., Sood, A., Hayward, C., Dupuis, J., Hall, I. P., Brusselle, G. G., Tobin, M. D. & London, S. J., 2 Feb 2016, In : PLoS ONE. 11, 2, p. 1-17 17 p., e0147388.

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Chronic widespread bodily pain is increased among individuals with history of fracture: findings from UK Biobank

Walker-Bone, K., Harvey, N. C., Ntani, G., Tinati, T., Jones, G. T., Smith, B. H., Macfarlane, G. J. & Cooper, C., 17 Dec 2016, In : Archives of Osteoporosis. 11, 1, p. 1-10 10 p., 1.

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5 Citations (Scopus)
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Common polygenic risk for autism spectrum disorder (ASD) is associated with cognitive ability in the general population

Clarke, T. K., Lupton, M. K., Fernandez-Pujals, A. M., Starr, J., Davies, G., Cox, S., Pattie, A., Liewald, D. C., Hall, L. S., MacIntyre, D. J., Smith, B. H., Hocking, L. J., Padmanabhan, S., Thomson, P. A., Hayward, C., Hansell, N. K., Montgomery, G. W., Medland, S. E., Martin, N. G., Wright, M. J. & 3 others, Porteous, D. J., Deary, I. J. & McIntosh, A. M., Mar 2016, In : Molecular Psychiatry. 21, 3, p. 419-425 7 p.

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57 Citations (Scopus)
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Corrigendum to Genome-wide analysis of over 106 000 individuals identifies 9 neuroticism-associated loci

Smith, D. J., Escott-Price, V., Davies, G., Bailey, M. E. S., Colodro-Conde, L., Ward, J., Vedernikov, A., Marioni, R., Cullen, B., Lyall, D., Hagenaars, S. P., Liewald, D. C. M., Luciano, M., Gale, C. R., Ritchie, S. J., Hayward, C., Nicholl, B., Bulik-Sullivan, B., Adams, M., Couvy-Duchesne, B. & 12 others, Graham, N., Mackay, D., Evans, J., Smith, B. H., Porteous, D. J., Medland, S. E., Martin, N. G., Holmans, P., McIntosh, A. M., Pell, J. P., Deary, I. J. & O'Donovan, M. C., 13 Sep 2016, In : Molecular Psychiatry. 21, p. 1643-1644 2 p.

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Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12

Jackson, V. E., Ntalla, I., Sayers, I., Morris, R., Whincup, P., Casas, J-P., Amuzu, A., Choi, M., Dale, C., Kumari, M., Engmann, J., Kalsheker, N., Chappell, S., Guetta-Baranes, T., McKeever, T. M., Palmer, C. N. A., Tavendale, R., Holloway, J. W., Sayer, A. A., Dennison, E. M. & 20 others, Cooper, C., Bafadhel, M., Barker, B., Brightling, C., Bolton, C. E., John, M. E., Parker, S. G., Moffat, M. F., Wardlaw, A. J., Connolly, M. J., Porteous, D. J., Smith, B. H., Padmanabhan, S., Hocking, L., Stirrups, K. E., Deloukas, P., Strachan, D. P., Hall, I. P., Tobin, M. D. & Wain, L. V., Jun 2016, In : Thorax. 71, 6, p. 501-509 9 p.

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Exploring peer-mentoring for community dwelling older adults with chronic low back pain: a qualitative study

Cooper, K., Schofield, P., Klein, S., Smith, B. & Mary Jehu, L., May 2016, In : Physiotherapy. 8 p.

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Genetic and environmental risk for chronic pain and the contribution of risk variants for major depressive disorder: a family-based mixed-model analysis

McIntosh, A. M., Hall, L. S., Zeng, Y., Adams, M. J., Gibson, J., Wigmore, E., Hagenaars, S. P., Davies, G., Fernandez-Pujals, A. M., Campbell, A. I., Clarke, T-K., Hayward, C., Haley, C. S., Porteous, D. J., Deary, I. J., Smith, D. J., Nicholl, B. I., Hinds, D. A., Jones, A. V., Scollen, S. & 3 others, Meng, W., Smith, B. H. & Hocking, L. J., 16 Aug 2016, In : PLoS Medicine. 13, 8, p. 1-17 17 p., e1002090.

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Genetic variants linked to education predict longevity

22 Nov 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 47, p. 13366-13371 6 p.

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33 Citations (Scopus)
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Genome-wide analysis of over 106  000 individuals identifies 9 neuroticism-associated loci

Smith, D. J., Escott-Price, V., Davies, G., Bailey, M. E. S., Colodro-Conde, L., Ward, J., Vedernikov, A., Marioni, R., Cullen, B., Lyall, D., Hagenaars, S. P., Liewald, D. C. M., Luciano, M., Gale, C. R., Ritchie, S. J., Hayward, C., Nicholl, B., Bulik-Sullivan, B., Adams, M., Couvy-Duchesne, B. & 12 others, Graham, N., Mackay, D., Evans, J., Smith, B. H., Porteous, D. J., Medland, S. E., Martin, N. G., Holmans, P., McIntosh, A. M., Pell, J. P., Deary, I. J. & O'Donovan, M. C., Jun 2016, In : Molecular Psychiatry. 21, 6, p. 749-757 9 p.

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Genome-wide association study identifies 74 loci associated with educational attainment

Okbay, A., Beauchamp, J. P., Fontana, M. A., Lee, J. J., Pers, T. H., Rietveld, C. A., Turley, P., Chen, G-B., Emilsson, V., Meddens, S. F. W., Oskarsson, S., Pickrell, J. K., Thom, K., Timshel, P., de Vlaming, R., Abdellaoui, A., Ahluwalia, T. S., Bacelis, J., Baumbach, C., Bjornsdottir, G. & 31 others, Brandsma, J. H., Pina Concas, M., Derringer, J., Furlotte, N. A., Galesloot, T. E., Girotto, G., Gupta, R., Hall, L. M., Harris, S. E., Hofer, E., Horikoshi, M., Huffman, J. E., Kaasik, K., Kalafati, I. P., Karlsson, R., Kong, A., Lahti, J., van der Lee, S. J., deLeeuw, C., Lind, P. A., Lindgren, K-O., Liu, T., Mangino, M., Marten, J., Mihailov, E., Miller, M. B., van der Most, P. J., Oldmeadow, C., Payton, A., Smith, B. H. & LifeLines Cohort Study, 26 May 2016, In : Nature. 533, 7604, p. 539-542 4 p.

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GWAS for executive function and processing speed suggests involvement of the CADM2 gene

Ibrahim-Verbaas, C. A., Bressler, J., Debette, S., Schuur, M., Smith, A. V., Bis, J. C., Davies, G., Trompet, S., Smith, J. A., Wolf, C., Chibnik, L. B., Liu, Y., Vitart, V., Kirin, M., Petrovic, K., Polasek, O., Zgaga, L., Fawns-Ritchie, C., Hoffmann, P., Karjalainen, J. & 106 others, Lahti, J., Llewellyn, D. J., Schmidt, C. O., Mather, K. A., Chouraki, V., Sun, Q., Resnick, S. M., Rose, L. M., Oldmeadow, C., Stewart, M., Smith, B. H., Gudnason, V., Yang, Q., Mirza, S. S., Jukema, J. W., DeJager, P. L., Harris, T. B., Liewald, D. C., Amin, N., Coker, L. H., Stegle, O., Lopez, O. L., Schmidt, R., Teumer, A., Ford, I., Karbalai, N., Becker, J. T., Jonsdottir, M. K., Au, R., Fehrmann, R. S. N., Herms, S., Nalls, M., Zhao, W., Turner, S. T., Yaffe, K., Lohman, K., Van Swieten, J. C., Kardia, S. L. R., Knopman, D. S., Meeks, W. M., Heiss, G., Holliday, E. G., Schofield, P. W., Tanaka, T., Stott, D. J., Wang, J., Ridker, P., Gow, A. J., Pattie, A., Starr, J. M., Hocking, L. J., Armstrong, N. J., McLachlan, S., Shulman, J. M., Pilling, L. C., Eiriksdottir, G., Scott, R. J., Kochan, N. A., Palotie, A., Hsieh, Y. C., Eriksson, J. G., Penman, A., Gottesman, R. F., Oostra, B. A., Yu, L., DeStefano, A. L., Beiser, A., Garcia, M., Rotter, J. I., Nöthen, M. M., Hofman, A., Slagboom, P. E., Westendorp, R. G. J., Buckley, B. M., Wolf, P. A., Uitterlinden, A. G., Psaty, B. M., Grabe, H. J., Bandinelli, S., Chasman, D. I., Grodstein, F., Räikkönen, K., Lambert, J. C., Porteous, D. J., Price, J. F., Sachdev, P. S., Ferrucci, L., Attia, J. R., Rudan, I., Hayward, C., Wright, A. F., Wilson, J. F., Cichon, S., Franke, L., Schmidt, H., Ding, J., De Craen, A. J. M., Fornage, M., Bennett, D. A., Deary, I. J., Ikram, M. A., Launer, L. J., Fitzpatrick, A. L., Seshadri, S., Van Duijn, C. M. & Mosley, T. H., 1 Feb 2016, In : Molecular Psychiatry. 21, 2, p. 189-197 9 p.

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61 Citations (Scopus)
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Identification and management of chronic pain in primary care: a review

Mills, S., Torrance, N. & Smith, B. H., Feb 2016, In : Current Psychiatry Reports. 18, 22, 9 p., 22.

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35 Citations (Scopus)
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Neuropathic pain: an updated grading system for research and clinical practice

Finnerup, N. B., Haroutounian, S., Kamerman, P., Baron, R., Bennett, D. L. H., Bouhassira, D., Cruccu, G., Freeman, R., Hansson, P., Nurmikko, T., Raja, S. N., Rice, A. S. C., Serra, J., Smith, B. H., Treede, R-D. & Jensen, T. S., Aug 2016, In : Pain. 157, 8, p. 1599-1606 8 p.

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267 Citations (Scopus)
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Pain and the global burden of disease

Rice, A. S. C., Smith, B. H. & Blyth, F. M., Apr 2016, In : Pain. 157, 4, p. 791-796 6 p.

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75 Citations (Scopus)
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Pedigree- and SNP-Associated Genetics and Recent Environment are the Major Contributors to Anthropometric and Cardiometabolic Trait Variation

Xia, C., Amador, C., Huffman, J., Trochet, H., Campbell, A., Porteous, D., Generation Scotland, Hastie, N. D., Hayward, C., Vitart, V., Navarro, P. & Haley, C. S., 1 Feb 2016, In : PLoS Genetics. 12, 2, e1005804.

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30 Citations (Scopus)

Polygenic risk for alcohol dependence associates with alcohol consumption, cognitive function and social deprivation in a population-based cohort

Clarke, T-K., Smith, A. H., Gelernter, J., Kranzler, H. R., Farrer, L. A., Hall, L. S., Fernandez-Pujals, A. M., MacIntyre, D. J., Smith, B. H., Hocking, L. J., Padmanabhan, S., Hayward, C., Thomson, P. A., Porteous, D. J., Deary, I. J. & McIntosh, A. M., Mar 2016, In : Addiction Biology. 21, 2, p. 469-480 12 p.

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16 Citations (Scopus)
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Shared genetics and couple-associated environment are major contributors to the risk of both clinical and self-declared depression

Yanni, Z., Navarro, P., Xia, C., Amador, C., Fernandez-Pujals, A. M., Thomson, P. A., Campbell, A., Nagy, R., Clarke, T-K., Hafferty, J. D., Smith, B., Hocking, L. J., Padmanabhan, S., Hayward, C., MacIntrye, D. J., Porteous, D. J., Haley, C. S. & McIntosh, A. M., Dec 2016, In : EBioMedicine. 14, p. 161-167 7 p.

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17 Citations (Scopus)
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Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease

Johnson, M. R., Shkura, K., Langley, S. R., Delahaye-Duriez, A., Srivastava, P., Hill, W. D., Rackham, O. J. L., Davies, G., Harris, S. E., Moreno-Moral, A., Rotival, M., Speed, D., Petrovski, S., Katz, A., Hayward, C., Porteous, D. J., Smith, B. H., Padmanabhan, S., Hocking, L. J., Starr, J. M. & 14 others, Liewald, D. C., Visconti, A., Falchi, M., Bottolo, L., Rossetti, T., Danis, B., Mazzuferi, M., Foerch, P., Grote, A., Helmstaedter, C., Becker, A. J., Kaminski, R. M., Deary, I. J. & Petretto, E., 1 Feb 2016, In : Nature Neuroscience. 19, 2, p. 223-232 10 p.

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Timing, rates and spectra of human germline mutation

Rahbari, R., Wuster, A., Lindsay, S. J., Hardwick, R. J., Alexandrov, L. B., Al Turki, S., Dominiczak, A., Morris, A., Porteous, D., Smith, B., Stratton, M. R., UK10K Consortium & Hurles, M. E., Feb 2016, In : Nature Genetics. 48, 2, p. 126-133

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191 Citations (Scopus)
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2015

A classification of chronic pain for ICD-11

Treede, R-D., Rief, W., Barke, A., Aziz, Q., Bennett, M. I., Benoliel, R., Cohen, M., Evers, S., Finnerup, N. B., First, M. B., Giamberardino, M. A., Kaasa, S., Kosek, E., Lavandʼhomme, P., Nicholas, M., Perrot, S., Scholz, J., Schug, S., Smith, B. H., Svensson, P. & 2 others, Vlaeyen, J. W. S. & Wang, S-J., Jun 2015, In : Pain. 156, 6, p. 1003-1007 5 p.

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551 Citations (Scopus)

A genome-wide association study provides evidence of sex-specific involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) with diabetic neuropathic pain

Meng, W., Deshmukh, H. A., Donnelly, L. A., Wellcome Trust Case Control Consortium 2, Surrogate Markers for Micro- and Macro-Vascular Hard Endpoints for Innovative Diabetes Tools (SUMMIT) Study Group, Torrance, N., Colhoun, H. M., Palmer, C. N. A. & Smith, B. H., Oct 2015, In : EBioMedicine. 2, 10, p. 1386-1393 8 p.

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