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  • 2018
  • 2017
  • 2014
  • 2013
  • 2011

Author

  • Julian Blow
2018

Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing

Shoaib, M., Walter, D., Gillespie, P. J., Izard, F., Fahrenkrog, B., Lleres, D., Lerdrup, M., Johansen, J. V., Hansen, K., Julien, E., Blow, J. J. & Sørensen, C. S., 12 Sep 2018, In : Nature Communications. 9, 1, p. 1-11 11 p., 3704.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
123 Downloads (Pure)

Lgr5+ intestinal stem cells reside in an unlicensed G1 phase

Carroll, T., Newton, I., Chen, Y., Blow, J. & Nathke, I., 7 May 2018, In : Journal of Cell Biology. 217, 5, p. 1667-1685 19 p.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
189 Downloads (Pure)

The Anthelmintic Drug Niclosamide and Its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1

Barini, E., Miccoli, A., Tinarelli, F., Mulholland, K., Kadri, H., Khanim, F., Stojanovski, L., Read, K. D., Burness, K., Blow, J. J., Mehellou, Y. & Muqit, M. M. K., 2 Mar 2018, In : ChemBioChem. 19, 5, p. 425-429 5 p.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
155 Downloads (Pure)
2017

Reversal of DDK-mediated MCM phosphorylation by Rif1-PP1 regulates replication initiation and replisome stability independently of ATR/Chk1

Alver, R. C., Chadha, G. S., Gillespie, P. J. & Blow, J. J., 7 Mar 2017, In : Cell Reports. 18, 10, p. 2508-2520 13 p.

Research output: Contribution to journalArticle

Open Access
File
42 Citations (Scopus)
168 Downloads (Pure)

The High-Affinity Interaction between ORC and DNA that Is Required for Replication Licensing Is Inhibited by 2-Arylquinolin-4-Amines

Gardner, N. J., Gillespie, P. J., Carrington, J. T., Shanks, E. J., McElroy, S. P., Haagensen, E. J., Frearson, J. A., Woodland, A. & Blow, J. J., 17 Aug 2017, In : Cell Chemical Biology. 24, 8, p. 981-992.e4 16 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
149 Downloads (Pure)
2014

Buffered Qualitative Stability explains the robustness and evolvability of transcriptional networks

Albergante, L., Blow, J. J. & Newman, T. J., 2 Sep 2014, In : eLife. 3, p. 1-28 28 p., e02863.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
177 Downloads (Pure)
Open Access
27 Citations (Scopus)

The contribution of dormant origins to genome stability: from cell biology to human genetics

Alver, R. C., Chadha, G. S. & Blow, J. J., Jul 2014, In : DNA Repair. 19, p. 182-189 8 p.

Research output: Contribution to journalArticle

Open Access
File
50 Citations (Scopus)
223 Downloads (Pure)

Xenopus Cdc7 executes its essential function early in S phase and is counteracted by checkpoint-regulated protein phosphatase 1

Poh, W. T., Chadha, G. S., Gillespie, P. J., Kaldis, P. & Blow, J. J., 8 Jan 2014, In : Open Biology. 4, January, 130138.

Research output: Contribution to journalArticle

Open Access
File
21 Citations (Scopus)
142 Downloads (Pure)
2013

Combinatorial regulation of meiotic holliday junction resolution in C. elegans by HIM-6 (BLM) helicase, SLX-4, and the SLX-1, MUS-81 and XPF-1 nucleases

Agostinho, A., Meier, B., Sonneville, R., Jagut, M., Woglar, A., Blow, J., Jantsch, V. & Gartner, A., 18 Jul 2013, In : PLoS Genetics. 9, 7, e1003591.

Research output: Contribution to journalArticle

53 Citations (Scopus)

Deregulated origin licensing leads to chromosomal breaks by rereplication of a gapped DNA template

Neelsen, K. J., Zanini, I. M. Y., Mijic, S., Herrador, R., Zellweger, R., Chaudhuri, A. R., Creavin, K., Blow, J. J. & Lopes, M., 1 Dec 2013, In : Genes and Development. 27, 23, p. 2537-2542 6 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Kinetochores coordinate pericentromeric cohesion and early DNA replication by Cdc7-Dbf4 kinase recruitment

Natsume, T., Müller, C. A., Katou, Y., Retkute, R., Gierlinski, M., Araki, H., Blow, J. J., Shirahige, K., Nieduszynski, C. A. & Tanaka, T. U., 6 Jun 2013, In : Molecular Cell. 50, 5, p. 661-674 14 p.

Research output: Contribution to journalArticle

86 Citations (Scopus)

Mcm8 and Mcm9 form a dimeric complex in Xenopus laevis egg extract that is not essential for DNA replication initiation

Gambus, A. & Blow, J. J., 15 Apr 2013, In : Cell Cycle. 12, 8, p. 1225-1232 8 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

PHD1 links cell-cycle progression to oxygen sensing through hydroxylation of the centrosomal protein Cep192

Moser, S. C., Bensaddek, D., Ortmann, B., Maure, J-F., Mudie, S., Blow, J. J., Lamond, A. I., Swedlow, J. R. & Rocha, S., 26 Aug 2013, In : Developmental Cell. 26, 4, p. 381-392 12 p.

Research output: Contribution to journalArticle

43 Citations (Scopus)

Replisome stall events have shaped the distribution of replication origins in the genomes of yeasts

Newman, T. J., Mamun, M. A., Nieduszynski, C. A. & Blow, J. J., Nov 2013, In : Nucleic Acids Research. 41, 21, p. 9705-9718 14 p.

Research output: Contribution to journalArticle

33 Citations (Scopus)

Stochastic association of neighboring replicons creates replication factories in budding yeast

Saner, N., Karschau, J., Natsume, T., Gierlinski, M., Retkute, R., Hawkins, M., Nieduszynski, C. A., Blow, J. J., de Moura, A. P. S. & Tanaka, T. U., 2013, In : Journal of Cell Biology. 202, 7, p. 1001-1012 12 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

The Geminin and Idas coiled coils preferentially form a heterodimer that inhibits Geminin function in DNA replication licensing

Caillat, C., Pefani, D-E., Gillespie, P. J., Taraviras, S., Blow, J. J., Lygerou, Z. & Perrakis, A., Nov 2013, In : Journal of Biological Chemistry. 288, 44, p. 31624-31634 11 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)
2011

A Role for Dormant Origins in Tumor Suppression

Klotz-Noack, K. & Blow, J. J., 4 Mar 2011, In : Molecular Cell. 41, 5, p. 495-496 2 p.

Research output: Contribution to journalEditorial

6 Citations (Scopus)

Biphasic chromatin binding of histone chaperone FACT during eukaryotic chromatin DNA replication

Kundu, L. R., Seki, M., Watanabe, N., Murofushi, H., Furukohri, A., Waga, S., Score, A. J., Blow, J. J., Horikoshi, M., Enomoto, T. & Tada, S., Jun 2011, In : Biochimica et Biophysica Acta. Molecular Cell Research. 1813, 6, p. 1129-1136 8 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

CDC-48/p97 Coordinates CDT-1 Degradation with GINS Chromatin Dissociation to Ensure Faithful DNA Replication

Franz, A., Orth, M., Pirson, P. A., Sonneville, R., Blow, J. J., Gartner, A., Stemmann, O. & Hoppe, T., 7 Oct 2011, In : Molecular Cell. 44, 1, p. 85-96 12 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)

Evidence for a mammalian late-G1 phase inhibitor of replication licensing distinct from geminin or Cdk activity

Sasaki, T., Li, A., Gillespie, P. J., Blow, J. J. & Gilbert, D. M., Sep 2011, In : Nucleus. 2, 5, p. 455-464

Research output: Contribution to journalArticle

4 Citations (Scopus)

How dormant origins promote complete genome replication

Blow, J. J., Ge, X. Q. & Jackson, D. A., Aug 2011, In : Trends in Biochemical Sciences. 36, 8, p. 405-414 10 p.

Research output: Contribution to journalReview article

145 Citations (Scopus)

MCM2-7 Form Double Hexamers at Licensed Origins in Xenopus Egg Extract

Gambus, A., Khoudoli, G. A., Jones, R. C. & Blow, J. J., 1 Apr 2011, In : Journal of Biological Chemistry. 286, 13, p. 11855-11864 10 p.

Research output: Contribution to journalArticle

95 Citations (Scopus)