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  Allopurinol use is associated with greater functional gains in older rehabilitation patients

  Beveridge, L. A., Ramage, L., McMurdo, M. E. T., George, J. & Witham, M. D., 2013, In: Age and Ageing. 42, 3, p. 400-404 5 p.

  Research output: Contribution to journal › Article › peer-review
  20 Citations (Scopus)

• Allosteric activation of trypanosomatid deoxyhypusine synthase by a catalytically dead paralog

  Nguyen, S., Jones, D. C., Wyllie, S., Fairlamb, A. H. & Phillips, M. A., 24 May 2013, In: Journal of Biological Chemistry. 288, 21, p. 15256-15267 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • deoxyhypusine synthase
  • Spermidine
  • Enzyme activity
  • Biosynthesis
  • Eflornithine
  34 Citations (Scopus)

  110 Downloads (Pure)

• Allosteric targeting of the Fanconi anemia ubiquitin-conjugating enzyme Ube2T by fragment screening

  Morreale, F., Bortoluzzi, A., Chaugule, V., Arkinson, C., Walden, H. & Ciulli, A., 11 May 2017, In: Journal of Medicinal Chemistry. 60, 9, p. 4093-4098 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Ubiquitin-Conjugating Enzymes
  • Fanconi Anemia
  • DNA Repair
  • Binding Sites
  • In Vitro Techniques
  8 Citations (Scopus)

  203 Downloads (Pure)

• Alloyed quaternary/binary core/shell quantum dot-graphene oxide nanocomposite: Preparation, characterization and application as a fluorescence “switch ON” probe for environmental pollutants

  Adegoke, O., Montaseri, H., Nsibande, S. A. & Forbes, P. B. C., 5 Oct 2017, In: Journal of Alloys and Compounds. 720, p. 70-78 9 p.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• A longitudinal examination of neuropsychological and clinical functioning in boys with attention deficit hyperactivity disorder (ADHD): improvements in executive functioning do not explain clinical improvement

  Coghill, D. R., Hayward, D., Rhodes, S. M., Grimmer, C. & Matthews, K., Apr 2014, In: Psychological Medicine. 44, 5, p. 1087-1099 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Attention Deficit Disorder with Hyperactivity
  • Biomarkers
  • Neuropsychological Tests
  78 Citations (Scopus)

• A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk

  Manning, A., Highland, H. M., Gasser, J., Sim, X., Tukiainen, T., Fontanillas, P., Grarup, N., Rivas, M. A., Mahajan, A., Locke, A. E., Cingolani, P., Pers, T. H., Viñuela, A., Brown, A. A., Wu, Y., Flannick, J., Fuchsberger, C., Gamazon, E. R., Gaulton, K. J., Im, H. K. & 242 others, Teslovich, T. M., Blackwell, T. W., Bork-Jensen, J., Burtt, N. P., Chen, Y., Green, T., Hartl, C., Kang, H. M., Kumar, A., Ladenvall, C., Ma, C., Moutsianas, L., Pearson, R. D., Perry, J. R. B., Rayner, N. W., Robertson, N. R., Scott, L. J., van de Bunt, M., Eriksson, J. G., Jula, A., Koskinen, S., Lehtimäki, T., Palotie, A., Raitakari, O. T., Jacobs, S. B., Wessel, J., Chu, A. Y., Scott, R. A., Goodarzi, M. O., Blancher, C., Buck, G., Buck, D., Chines, P. S., Gabriel, S., Gjesing, A. P., Groves, C. J., Hollensted, M., Huyghe, J. R., Jackson, A. U., Jun, G., Justesen, J. M., Mangino, M., Murphy, J., Neville, M., Onofrio, R., Small, K. S., Stringham, H. M., Trakalo, J., Banks, E., Carey, J., Carneiro, M. O., DePristo, M., Farjoun, Y., Fennell, T., Goldstein, J. I., Grant, G., Hrabé de Angelis, M., Maguire, J., Neale, B. M., Poplin, R., Purcell, S., Schwarzmayr, T., Shakir, K., Smith, J. D., Strom, T. M., Wieland, T., Lindstrom, J., Brandslund, I., Christensen, C., Surdulescu, G. L., Lakka, T. A., Doney, A. S. F., Nilsson, P., Wareham, N. J., Langenberg, C., Varga, T. V., Franks, P. W., Rolandsson, O., Rosengren, A. H., Farook, V. S., Thameem, F., Puppala, S., Kumar, S., Lehman, D. M., Jenkinson, C. P., Curran, J. E., Fowler, S. P., Arya, R., DeFronzo, R. A., Abboud, H. E., Syvänen, A-C., Hicks, P. J., Palmer, N. D., Ng, M. C. Y., Bowden, D. W., Freedman, B. I., Esko, T., Mägi, R., Milani, L., Mihailov, E., Metspalu, A., Narisu, N., Kinnunen, L., Bonnycastle, L. L., Swift, A., Pasko, D., Wood, A. R., Fadista, J., Pollin, T. I., Barzilai, N., Atzmon, G., Glaser, B., Thorand, B., Strauch, K., Peters, A., Roden, M., Müller-Nurasyid, M., Liang, L., Kriebel, J., Illig, T., Grallert, H., Gieger, C., Meisinger, C., Lannfelt, L., Musani, S. K., Griswold, M., Taylor, H. A., Wilson, G., Correa, A., Oksa, H., Scott, W. R., Afzal, U., Tan, S-T., Loh, M., Chambers, J. C., Sehmi, J., Kooner, J. S., Lehne, B., Cho, Y. S., Lee, J-Y., Han, B-G., Käräjämäki, A., Qi, Q., Qi, L., Huang, J., Hu, F. B., Melander, O., Orho-Melander, M., Below, J. E., Aguilar, D., Wong, T. Y., Liu, J., Khor, C-C., Chia, K. S., Lim, W. Y., Cheng, C-Y., Chan, E., Tai, E. S., Aung, T., Linneberg, A., Isomaa, B., Meitinger, T., Tuomi, T., Hakaste, L., Kravic, J., Jørgensen, M. E., Lauritzen, T., Deloukas, P., Stirrups, K. E., Owen, K. R., Farmer, A. J., Frayling, T. M., O'Rahilly, S. P., Walker, M., Levy, J. C., Hodgkiss, D., Hattersley, A. T., Kuulasmaa, T., Stančáková, A., Barroso, I., Bharadwaj, D., Chan, J., Chandak, G. R., Daly, M. J., Donnelly, P. J., Ebrahim, S. B., Elliott, P., Fingerlin, T., Froguel, P., Hu, C., Jia, W., Ma, R. C. W., McVean, G., Park, T., Prabhakaran, D., Sandhu, M., Scott, J., Sladek, R., Tandon, N., Teo, Y. Y., Zeggini, E., Watanabe, R. M., Koistinen, H. A., Kesaniemi, Y. A., Uusitupa, M., Spector, T. D., Salomaa, V., Rauramaa, R., Palmer, C. N. A., Prokopenko, I., Morris, A. D., Bergman, R. N., Collins, F. S., Lind, L., Ingelsson, E., Tuomilehto, J., Karpe, F., Groop, L., Jørgensen, T., Hansen, T., Pedersen, O., Kuusisto, J., Abecasis, G., Bell, G. I., Blangero, J., Cox, N. J., Duggirala, R., Seielstad, M., Wilson, J. G., Dupuis, J., Ripatti, S., Hanis, C. L., Florez, J. C., Mohlke, K. L., Meigs, J. B., Laakso, M., Morris, A. P., Boehnke, M., Altshuler, D., McCarthy, M. I., Gloyn, A. L. & Lindgren, C. M., Jul 2017, In: Diabetes. 66, 7, p. 2019-2032 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Fasting
  • Type 2 Diabetes Mellitus
  • Insulin
  • Exome
  • Population
  23 Citations (Scopus)

  37 Downloads (Pure)

• Alteration of endoplasmic reticulum lipid rafts contributes to lipotoxicity in pancreatic β-cells

  Boslem, E., Weir, J. M., MacIntosh, G., Sue, N., Cantley, J., Meikle, P. J. & Biden, T. J., 13 Sep 2013, In: Journal of Biological Chemistry. 288, 37, p. 26569-26582 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Sphingomyelins
  • Endoplasmic Reticulum
  • Palmitates
  • Lipids
  • ceramide glucosyltransferase
  63 Citations (Scopus)

• Altered amyloid precursor protein processing regulates glucose uptake and oxidation in cultured rodent myotubes

  Hamilton, D. L., Findlay, J. A., Montagut, G., Meakin, P. J., Bestow, D., Jalicy, S. M. & Ashford, M. L. J., Aug 2014, In: Diabetologia. 57, 8, p. 1684-1692 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Amyloid beta-Protein Precursor
  • Skeletal Muscle Fibers
  • Rodentia
  • Glucose
  • Enzymes
  10 Citations (Scopus)

  157 Downloads (Pure)

• Alternative caries management options for primary molars: 2.5-yr outcomes of a randomised clinical trial

  Santamaria, R. M., Innes, N., Machiulskiene, V., Schmoeckel, J., Alkilzy, M. & Splieth, C. H., 20 Dec 2017, In: Caries Research. 51, 6, p. 605-614

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Randomized Controlled Trials
  • Pulpitis
  • Nonparametric Statistics
  • Compomers
  • Therapeutics
  39 Citations (Scopus)

  288 Downloads (Pure)

• Alternative spaces of 'work' and inclusion for disabled people

  Hall, E. & Wilton, R., 2011, In: Disability & Society. 26, 7, p. 867-880 14 p.

  Research output: Contribution to journal › Article › peer-review
  51 Citations (Scopus)

• Alternative splicing at the intersection of biological timing, development, and stress responses

  Staiger, D. & Brown, J. W. S., Oct 2013, In: Plant Cell. 25, 10, p. 3640-56 17 p.

  Research output: Contribution to journal › Article › peer-review

  • alternative splicing
  • stress response
  • circadian clocks
  • genes
  • transcriptome
  302 Citations (Scopus)

• Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis

  Cookson, T. V. M., Castell, A., Bulloch, E. M. M., Evans, G. L., Short, F. L., Baker, E. N., Lott, J. S. & Parker, E. J., 9 Apr 2014, In: Biochemical Journal. 461, 1, p. 87-98 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Anthranilate Phosphoribosyltransferase
  • anthranilic acid
  • Mycobacterium tuberculosis
  • Phosphoribosyl Pyrophosphate
  • Substrates
  13 Citations (Scopus)

• Alternative ways of seeing the inner body: an arts-led approach to visualising MRI scan data

  McGhee, J. & Johnson, N., Feb 2014, In: Leonardo. 47, 1, p. 90-91 2 p.

  Research output: Contribution to journal › Article › peer-review

  • Magnetic Resonance Imaging
  • Art
  • Lead
  • Imagery
  • Artist
  1 Citation (Scopus)

• A mammography image set for research purposes using BI-RADS density classification

  Mercer, C., Hogg, P., Kelly, J., Borgen, R., Millington, S. R., Hilton, B., Enion, D. & Whelehan, P., Jul 2014, In: Radiologic Technology. 85, 6, p. 609-613 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Data Systems
  • Mammography
  • Breast
  • Breast Density
  • Observation
  1 Citation (Scopus)

• A mechanical signal transmitted by the flagellum controls signalling in Bacillus subtilis

  Cairns, L. S., Marlow, V. L., Bissett, E., Ostrowski, A. & Stanley-Wall, N. R., Oct 2013, In: Molecular Microbiology. 90, 1, p. 6-21 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Flagella
  • Bacillus subtilis
  • Biofilms
  • Signal Transduction
  • Exopeptidases
  82 Citations (Scopus)

• A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic dermatitis

  Naeem, A. S., Tommasi, C., Cole, C., Brown, S. J., Zhu, Y., Way, B., Willis Owen, S. A. G., Moffatt, M., Cookson, W. O., Harper, J. I., Di, W. L., Brown, S. J., Reinheckel, T. & O'Shaughnessy, R. F. L., Apr 2017, In: Journal of Allergy and Clinical Immunology. 139, 4, p. 1228-1241 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cathepsin H
  • Mechanistic Target of Rapamycin Complex 2
  • filaggrin
  • Mechanistic Target of Rapamycin Complex 1
  • Thymoma
  9 Citations (Scopus)

  214 Downloads (Pure)

• A MEMS-based electronic capsule for time controlled drug delivery in the alimentary canal

  Zhuang, Y., Hou, W., Zheng, X., Wang, Z., Zheng, J., Pi, X., Cui, J., Jiang, Y., Qian, S. & Peng, C., 10 Sep 2011, In: Sensors and Actuators A - Physical. 169, 1, p. 211-216 6 p.

  Research output: Contribution to journal › Article › peer-review
  9 Citations (Scopus)

• A meta-ethnography of the facilitators and barriers to successful implementation of patient complaints processes in health-care settings

  Scott, D. & Grant, S. M., Apr 2018, In: Health Expectations. 21, 2, p. 508-517 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cultural Anthropology
  • Delivery of Health Care
  • Social Responsibility
  • New Zealand
  • Sweden
  5 Citations (Scopus)

  201 Downloads (Pure)

• A method for automatic segmentation and splitting of hyperspectral images of raspberry plants collected in field conditions

  Williams, D., Britten, A., McCallum, S., Jones, H., Aitkenhead, M., Karley, A., Loades, K., Prashar, A. & Graham, J., 1 Nov 2017, In: Plant Methods. 13, p. 1-12 12 p., 74.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Rubus
  • hyperspectral imagery
  • raspberries
  • methodology
  • reflectance
  9 Citations (Scopus)

  170 Downloads (Pure)

• A methodological approach to assess the hazard of underground cavities subjected to environmental weathering

  Castellanza, R., Lollino, P. & Ciantia, M., Dec 2018, In: Tunnelling and Underground Space Technology. 82, p. 278-292 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Weathering
  • Hazards
  • cavity
  • Rocks
  • weathering
  6 Citations (Scopus)

  40 Downloads (Pure)

• A Micropower Miniature Piezoelectric Actuator for Implantable Middle Ear Hearing Device

  Wang, Z., Mills, R., Luo, H., Zheng, X., Hou, W., Wang, L., Brown, S. I. & Cuschieri, A., Feb 2011, In: IEEE Transactions on Biomedical Engineering. 58, 2, p. 452-458 7 p.

  Research output: Contribution to journal › Article › peer-review
  13 Citations (Scopus)

• Amine Containing Analogs of Sulindac for Cancer Prevention

  Mathew, B., Hobrath, J. V., Connelly, M. C., Guy, R. K. & Reynolds, R. C., 31 Jan 2018, In: Open Medicinal Chemistry Journal. 12, p. 1-12 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Sulindac
  • sulindac sulfide amide
  • Amines
  • Libraries
  • 3-(5-nitrofuryl)-7-(5-nitrofurfurylidene)-3,3a,4,5,6,7-hexahydro-2H-indazole
  152 Downloads (Pure)

• A minimum data set approach to post-mortem computed tomography reporting for anthropological biological profiling

  Brough, A. L., Morgan, B., Robinson, C., Black, S., Cunningham, C., Adams, C. & Rutty, G. N., Dec 2014, In: Forensic Science, Medicine and Pathology. 10, 4, p. 504-512 9 p.

  Research output: Contribution to journal › Article › peer-review
  22 Citations (Scopus)

• Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice

  Loftus, R. M., Assmann, N., Kedia-Mehta, N., O'Brien, K. L., Garcia, A., Gillespie, C., Hukelmann, J. L., Oefner, P. J., Lamond, A. I., Gardiner, C. M., Dettmer, K., Cantrell, D. A., Sinclair, L. V. & Finlay, D. K., 14 Jun 2018, In: Nature Communications. 9, 1, p. 1-15 15 p., 2341.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Oxidative Phosphorylation
  • amino acids
  • mice
  • Lymphocytes
  • Natural Killer Cells
  59 Citations (Scopus)

  171 Downloads (Pure)

• Amino acid neurotoxins in feathers of the Lesser Flamingo, Phoeniconaias minor

  Metcalf, J. S., Banack, S. A., Kotut, K., Krienitz, L. & Codd, G. A., Jan 2013, In: Chemosphere. 90, 2, p. 835-839 5 p.

  Research output: Contribution to journal › Article › peer-review

  • cyanobacterial toxin
  • Feathers
  • feather
  • Amino acids
  • Lakes
  24 Citations (Scopus)

• Aminoglycosides restore full-length type VII collagen by overcoming premature termination codons: therapeutic implications for dystrophic epidermolysis bullosa

  Cogan, J., Weinstein, J., Wang, X., Hou, Y., Martin, S., South, A. P., Woodley, D. T. & Chen, M., 23 Jul 2014, In: Molecular Therapy. 22, 10, p. 1741-1752 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Collagen Type VII
  • Epidermolysis Bullosa Dystrophica
  • Nonsense Codon
  • Aminoglycosides
  • Skin
  37 Citations (Scopus)

• A mixed-methods feasibility study protocol to assess the communication behaviours within the dental health professional-parent-child triad in a general dental practice setting

  Yuan, S., Humphris, G. M., Ross, A., MacPherson, L., Zhou, Y. & Freeman, R., 13 Aug 2018, In: Pilot and Feasibility Studies. 4, p. 1-9 9 p., 136.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Dental General Practices
  • Feasibility Studies
  • Communication
  • Tooth
  • Health
  3 Citations (Scopus)

  174 Downloads (Pure)

• A mobile phone intervention to reduce binge drinking among disadvantaged men: study protocol for a randomised controlled cost-effectiveness trial

  Crombie, I. K., Irvine, L., Williams, B., Sniehotta, F. F., Petrie, D., Evans, J. M. M., Emslie, C., Jones, C., Ricketts, I. W., Humphris, G., Norrie, J., Rice, P. & Slane, P. W., 19 Dec 2014, In: Trials. 15, 8 p., 494.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Binge Drinking
  • Cell Phone
  • Vulnerable Populations
  • Cost-Benefit Analysis
  • Text Messaging
  7 Citations (Scopus)

  167 Downloads (Pure)

• A model based criterion for gene expression calls using RNA-seq data

  Wagner, G. P., Kin, K. & Lynch, V. J., Sep 2013, In: Theory in Biosciences. 132, 3, p. 159-164 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Gene Expression
  • RNA
  • gene expression
  • Gene expression
  • Gene
  74 Citations (Scopus)

• A model for dynamic reconfiguration in service-oriented architectures

  Fiadeiro, J. L. & Lopes, A., 1 May 2013, In: Software and Systems Modeling. 12, 2, p. 349-367 19 p.

  Research output: Contribution to journal › Article › peer-review

  • Service-oriented Architecture
  • Dynamic Reconfiguration
  • Service-oriented
  • Service oriented architecture (SOA)
  • Architecture
  26 Citations (Scopus)

• A model of consultation in prostate cancer care: evidence from a systematic review

  Paterson, C. & Nabi, G., 2017, In: Cancer Nursing. 40, 4, p. 276-288 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Prostatic Neoplasms
  • Systematic Reviews
  • Referral and Consultation
  • Self-Management
  • Nurse Specialists
  13 Citations (Scopus)

  379 Downloads (Pure)

• A model of the transformative journey into reflexivity: an exploration into students' experiences of critical reflection

  Shaw, R., 15 Feb 2013, In: Reflective Practice. 14, 3, p. 319-335 17 p.

  Research output: Contribution to journal › Article › peer-review

  • Student Experience
  • Critical Reflection
  • Reflexivity
  • Learning Communities
  • Journey
  9 Citations (Scopus)

• A molecular explanation for the recessive nature of parkin-linked Parkinson's disease

  Spratt, D. E., Julio Martinez-Torres, R., Noh, Y. J., Mercier, P., Manczyk, N., Barber, K. R., Aguirre, J. D., Burchell, L., Purkiss, A., Walden, H. & Shaw, G. S., 1 Jan 2013, In: Nature Communications. 4, 12 p., 1983.

  Research output: Contribution to journal › Article › peer-review

  • Parkinson disease
  • mutations
  • Ubiquitin
  • Parkinsonian Disorders
  • Parkinson Disease
  87 Citations (Scopus)

• A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors

  Harrison, J. R., Brand, S., Smith, V., Robinson, D. A., Thompson, S., Smith, A., Davies, K., Mok, N., Torrie, L. S., Collie, I., Hallyburton, I., Norval, S., Simeons, F. R. C., Stojanovski, L., Frearson, J. A., Brenk, R., Wyatt, P. G., Gilbert, I. H. & Read, K. D., 12 Sep 2018, In: Journal of Medicinal Chemistry. 61, 18, p. 8374–8389 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • glycylpeptide N-tetradecanoyltransferase
  • African Trypanosomiasis
  • Crystallography
  • Trypanosoma brucei brucei
  • Central Nervous System Diseases
  18 Citations (Scopus)

  198 Downloads (Pure)

• A monovalent ion in the DNA binding interface of the eukaryotic junction-resolving enzyme GEN1

  Liu, Y., Freeman, A. D. J., Déclais, A-C. & Lilley, D. M. J., 16 Nov 2018, In: Nucleic Acids Research. 46, 20, p. 11089-11098 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Ions
  • DNA
  • Substrate Specificity
  • Enzymes
  • Catalytic Domain
  3 Citations (Scopus)

  110 Downloads (Pure)

• "A Morning Since Eight of Just Pure Grill": A Multischool Qualitative Study of Student Abuse

  Rees, C. E. & Monrouxe, L. V., Nov 2011, In: Academic Medicine: Journal of the Association of American Medical Colleges. 86, 11, p. 1374-1382 9 p.

  Research output: Contribution to journal › Article › peer-review
  46 Citations (Scopus)

• A Morphological identification cell cytotoxicity assay using cytoplasm-localized fluorescent probe (CLFP) to distinguish living and dead cells

  Lai, F., Shen, Z., Wen, H., Chen, J., Zhang, X., Lin, P., Yin, D., Cui, H. & Chen, X., 8 Jan 2017, In: Biochemical and Biophysical Research Communications. 482, 2, p. 257-263 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cytotoxicity
  • Assays
  • Fluorescent Dyes
  • Cytoplasm
  • Cells
  10 Citations (Scopus)

  400 Downloads (Pure)

• AMP-activated protein kinase: a cellular energy sensor with a key role in metabolic disorders and in cancer

  Hardie, D. G., Feb 2011, In: Biochemical Society Transactions. 39, p. 1-13 13 p.

  Research output: Contribution to journal › Article › peer-review
  123 Citations (Scopus)

• AMP-activated protein kinase (AMPK)α2 plays a role in determining the cellular fate of glucose in insulin-resistant mouse skeletal muscle

  Lee-Young, R. S., Bonner, J. S., Mayes, W. H., Iwueke, I., Barrick, B. A., Hasenour, C. M., Kang, L. & Wasserman, D. H., Mar 2013, In: Diabetologia. 56, 3, p. 608-617 10 p.

  Research output: Contribution to journal › Article › peer-review

  • AMP-Activated Protein Kinases
  • Skeletal Muscle
  • Insulin
  • Nitric Oxide Synthase Type II
  • Lipids
  18 Citations (Scopus)

• AMP-activated protein kinase activator A-769662 increases intracellular calcium and ATP release from astrocytes in an AMPK-independent manner

  Vlachaki Walker, J. M., Robb, J. L., Cruz, A. M., Malhi, A., Weightman Potter, P. G., Ashford, M. L. J., McCrimmon, R. J., Ellacott, K. L. J. & Beall, C., 21 Apr 2017, In: Diabetes, Obesity & Metabolism. 19, 7, p. 997-1005 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • A 769662
  • AMP-Activated Protein Kinases
  • Astrocytes
  • Adenosine Triphosphate
  • Calcium
  14 Citations (Scopus)

  290 Downloads (Pure)

• AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study

  Boyle, J. G., Logan, P. J., Jones, G. C., Small, M., Sattar, N., Connell, J. M. C., Cleland, S. J. & Salt, I. P., 2011, In: Diabetologia. 54, 7, p. 1799-1809 11 p.

  Research output: Contribution to journal › Article › peer-review
  54 Citations (Scopus)

• AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation

  Gowans, G. J., Hawley, S. A., Ross, F. A. & Hardie, D. G., 1 Oct 2013, In: Cell Metabolism. 18, 4, p. 556-566 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Adenosine Monophosphate
  • Phosphorylation
  • Adenosine Diphosphate
  • Adenosine Triphosphate
  272 Citations (Scopus)

  159 Downloads (Pure)

• AMPK: opposing the metabolic changes in both tumour cells and inflammatory cells?

  Dandapani, M. & Hardie, D. G., Apr 2013, In: Biochemical Society Transactions. 41, 2, p. 687-693 7 p.

  Research output: Contribution to journal › Article › peer-review
  34 Citations (Scopus)

• AMPK: a target for drugs and natural products with effects on both diabetes and cancer

  Hardie, D. G., Jul 2013, In: Diabetes. 62, 7, p. 2164-2172 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Biological Products
  • Metformin
  • Pharmaceutical Preparations
  • Salicylates
  263 Citations (Scopus)

  133 Downloads (Pure)

• AMPK: regulating energy balance at the cellular and whole body levels

  Hardie, D. G. & Ashford, M. L. J., Mar 2014, In: Physiology. 29, 2, p. 99-107 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Adenine Nucleotides
  • AMP-Activated Protein Kinases
  • Eukaryota
  • Energy Intake
  • Energy Metabolism
  161 Citations (Scopus)

  160 Downloads (Pure)

• AMPK modulates glucose-sensing in insulin-secreting cells by altered phosphotransfer to KATP channels

  Beall, C., Watterson, K. R., McCrimmon, R. J. & Ashford, M. L. J., Jun 2013, In: Journal of Bioenergetics and Biomembranes. 45, 3, p. 229-241 13 p.

  Research output: Contribution to journal › Article › peer-review

  • KATP Channels
  • AMP-Activated Protein Kinases
  • Insulin-Secreting Cells
  • Glucose
  • Adenylate Kinase
  14 Citations (Scopus)

• AMPK-sensing energy while talking to other signaling pathways

  Hardie, D. G., 2 Dec 2014, In: Cell Metabolism. 20, 6, p. 939-952 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • AMP-Activated Protein Kinases
  • Mechanistic Target of Rapamycin Complex 1
  • Nutrients
  • AMP-activated protein kinase kinase
  • Eukaryota
  311 Citations (Scopus)

  151 Downloads (Pure)

• AMPKα1: a glucose sensor that controls CD8 T-cell memory

  Rolf, J., Zarrouk, M., Finlay, D. K., Foretz, M., Viollet, B. & Cantrell, D. A., Apr 2013, In: European Journal of Immunology. 43, 4, p. 889-896 8 p.

  Research output: Contribution to journal › Article › peer-review
  133 Citations (Scopus)

• Amputation-free survival in 17,353 people at high risk for foot ulceration in diabetes: a national observational study

  Scottish Diabetes Research Network Epidemiology Group, Vadiveloo, T., Jeffcoate, W., Donnan, P. T., Colhoun, H. C., McGurnaghan, S., Wild, S., McCrimmon, R. & Leese, G. P., Dec 2018, In: Diabetologia. 61, 12, p. 2590-2597 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Amputation
  • Ulcer
  • Foot
  • Observational Studies
  • Scotland
  15 Citations (Scopus)

  183 Downloads (Pure)

• A Multicellular Model of Intestinal Crypt Buckling and Fission

  Almet, A. A., Hughes, B. D., Landman, K. A., Näthke, I. S. & Osborne, J. M., Feb 2018, In: Bulletin of Mathematical Biology. 80, 2, p. 335-359 25 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • intestinal crypts
  • buckling
  • Buckling
  • Organoids
  • Tissue
  3 Citations (Scopus)

  224 Downloads (Pure)