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AMP-activated protein kinase: a cellular energy sensor with a key role in metabolic disorders and in cancer
Hardie, D. G., Feb 2011, In: Biochemical Society Transactions. 39, p. 1-13 13 p.Research output: Contribution to journal › Article › peer-review
125 Citations (Scopus) -
AMP-activated protein kinase (AMPK)α2 plays a role in determining the cellular fate of glucose in insulin-resistant mouse skeletal muscle
Lee-Young, R. S., Bonner, J. S., Mayes, W. H., Iwueke, I., Barrick, B. A., Hasenour, C. M., Kang, L. & Wasserman, D. H., Mar 2013, In: Diabetologia. 56, 3, p. 608-617 10 p.Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus) -
AMP-activated protein kinase activator A-769662 increases intracellular calcium and ATP release from astrocytes in an AMPK-independent manner
Vlachaki Walker, J. M., Robb, J. L., Cruz, A. M., Malhi, A., Weightman Potter, P. G., Ashford, M. L. J., McCrimmon, R. J., Ellacott, K. L. J. & Beall, C., 21 Apr 2017, In: Diabetes, Obesity & Metabolism. 19, 7, p. 997-1005 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)303 Downloads (Pure) -
AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study
Boyle, J. G., Logan, P. J., Jones, G. C., Small, M., Sattar, N., Connell, J. M. C., Cleland, S. J. & Salt, I. P., 2011, In: Diabetologia. 54, 7, p. 1799-1809 11 p.Research output: Contribution to journal › Article › peer-review
56 Citations (Scopus) -
Amphiphilic oxygenated amorphous carbon-graphite buckypapers with gas sensitivity to polar and non-polar VOCs
Homaeigohar, S., Sep 2019, In: Nanomaterials. 9, 9, p. 1-14 14 p., 1343.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)22 Downloads (Pure) -
AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation
Gowans, G. J., Hawley, S. A., Ross, F. A. & Hardie, D. G., 1 Oct 2013, In: Cell Metabolism. 18, 4, p. 556-566 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile278 Citations (Scopus)175 Downloads (Pure) -
AMPK: regulating energy balance at the cellular and whole body levels
Hardie, D. G. & Ashford, M. L. J., Mar 2014, In: Physiology. 29, 2, p. 99-107 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile164 Citations (Scopus)175 Downloads (Pure) -
AMPK: opposing the metabolic changes in both tumour cells and inflammatory cells?
Dandapani, M. & Hardie, D. G., Apr 2013, In: Biochemical Society Transactions. 41, 2, p. 687-693 7 p.Research output: Contribution to journal › Article › peer-review
36 Citations (Scopus) -
AMPK: a target for drugs and natural products with effects on both diabetes and cancer
Hardie, D. G., Jul 2013, In: Diabetes. 62, 7, p. 2164-2172 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile266 Citations (Scopus)154 Downloads (Pure) -
AMPK modulates glucose-sensing in insulin-secreting cells by altered phosphotransfer to KATP channels
Beall, C., Watterson, K. R., McCrimmon, R. J. & Ashford, M. L. J., Jun 2013, In: Journal of Bioenergetics and Biomembranes. 45, 3, p. 229-241 13 p.Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus) -
AMPK-sensing energy while talking to other signaling pathways
Hardie, D. G., 2 Dec 2014, In: Cell Metabolism. 20, 6, p. 939-952 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile324 Citations (Scopus)167 Downloads (Pure) -
AMPKα1: a glucose sensor that controls CD8 T-cell memory
Rolf, J., Zarrouk, M., Finlay, D. K., Foretz, M., Viollet, B. & Cantrell, D. A., Apr 2013, In: European Journal of Immunology. 43, 4, p. 889-896 8 p.Research output: Contribution to journal › Article › peer-review
139 Citations (Scopus) -
Amputation-free survival in 17,353 people at high risk for foot ulceration in diabetes: a national observational study
Scottish Diabetes Research Network Epidemiology Group, Vadiveloo, T., Jeffcoate, W., Donnan, P. T., Colhoun, H. C., McGurnaghan, S., Wild, S., McCrimmon, R. & Leese, G. P., Dec 2018, In: Diabetologia. 61, 12, p. 2590-2597 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Citations (Scopus)208 Downloads (Pure) -
A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure
LifeLines Cohort Study, Sung, Y. J., de Las Fuentes, L., Winkler, T. W., Chasman, D. I., Bentley, A. R., Kraja, A. T., Ntalla, I., Warren, H. R., Guo, X., Schwander, K., Manning, A. K., Brown, M. R., Aschard, H., Feitosa, M. F., Franceschini, N., Lu, Y., Cheng, C-Y., Sim, X., Vojinovic, D. & 40 others, , 1 Aug 2019, In: Human Molecular Genetics. 28, 15, p. 2615-2633 19 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)84 Downloads (Pure) -
A Multicellular Model of Intestinal Crypt Buckling and Fission
Almet, A. A., Hughes, B. D., Landman, K. A., Näthke, I. S. & Osborne, J. M., Feb 2018, In: Bulletin of Mathematical Biology. 80, 2, p. 335-359 25 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)235 Downloads (Pure) -
A Multicenter, Randomized, Placebo-Controlled Trial of Atorvastatin for the Primary Prevention of Cardiovascular Events in Patients With Rheumatoid Arthritis: A multicenter, randomized, placebo controlled trial
Kitas, G. D., Nightingale, P., Armitage, J., Sattar, N., Belch, J. J. F. & Symmons, D. P. M., Sep 2019, In: Arthritis and Rheumatology. 71, 9, p. 1437-1449 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile33 Citations (Scopus)48 Downloads (Pure) -
A multicentre parallel-group randomised trial assessing multiparametric MRI characterisation and image-guided biopsy of prostate in men suspected of having prostate cancer: MULTIPROS study protocol
Szewczyk-Bieda, M., Wei, C., Coll, K., Gandy, S., Donnan, P., Ragupathy, S. K. A., Singh, P., Wilson, J. & Nabi, G., 21 Nov 2019, In: Trials. 20, p. 1-8 8 p., 638.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)80 Downloads (Pure) -
A Multi-disciplinary Approach to the Archaeological Investigation of a Bedrock-Dominated Shallow-Marine Landscape: An example from the Bay of Firth, Orkney, UK
Bates, M. R., Nayling, N., Bates, R., Dawson, S., Huws, D. & Wickham-Jones, C., Mar 2013, In: International Journal of Nautical Archaeology. 42, 1, p. 24-43 20 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
A multidisciplinary intervention to reduce antibiotic duration in lower respiratory tract infections
Murray, C., Shaw, A., Lloyd, M., Smith, R. P., Fardon, T. C., Schembri, S. & Chalmers, J. D., Feb 2014, In: Journal of Antimicrobial Chemotherapy. 69, 2, p. 515-518 4 p.Research output: Contribution to journal › Article › peer-review
29 Citations (Scopus) -
A multifaceted approach to identify non-specific enzyme inhibition: Application to Mycobacterium tuberculosis shikimate kinase
Alturki, M. S., Fuanta, N. R., Jarrard, M. A., Hobrath, J. V., Goodwin, D. C., Rants'o, T. A. & Calderón, A. I., 15 Feb 2018, In: Bioorganic and Medicinal Chemistry Letters. 28, 4, p. 802-808 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)169 Downloads (Pure) -
A multifaceted intervention to improve sepsis management in general hospital wards with evaluation using segmented regression of interrupted time series
Marwick, C. A., Guthrie, B., Pringle, J. E. C., Evans, J. M. M., Nathwani, D., Donnan, P. T. & Davey, P. G., Dec 2014, In: BMJ Quality & Safety. 23, 12, 8 p., e2.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
A Multifunctional Protease Inhibitor To Regulate Endolysosomal Function
van Kasteren, S. I., Berlin, I., Colbert, J. D., Keane, D., Ovaa, H. & Watts, C., Nov 2011, In: ACS Chemical Biology. 6, 11, p. 1198-1204 7 p.Research output: Contribution to journal › Article › peer-review
16 Citations (Scopus) -
A multigenic model to predict risk of ischemic stroke in subjects with type 2 diabetes
Pola, R., Kimber, C. H., Giarretta, I., Doney, A., Morris, A. M., Gaetani, E. & Palmer, C. N., Jun 2011, In: Atherosclerosis. Supplements. 12, 1, p. 127-127 1 p.Research output: Contribution to journal › Article › peer-review
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A multimodal approach to cardiovascular risk stratification in patients with type 2 diabetes incorporating retinal, genomic and clinical features
Fetit, A., Doney, A., Hogg, S., Wang, R., MacGillivray, T., Wardlaw, J. M., Doubal, F. N., McKay, G. J., McKenna, S. & Trucco, E., 5 Mar 2019, In: Scientific Reports. 9, 10 p., 3591.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)145 Downloads (Pure) -
A multiprotein binding interface in an intrinsically disordered region of the tumor suppressor protein interferon regulatory factor-1
Narayan, V., Halada, P., Hernychová, L., Chong, Y. P., Žáková, J., Hupp, T. R., Vojtesek, B. & Ball, K. L., 22 Apr 2011, In: Journal of Biological Chemistry. 286, 16, p. 14291-14303 13 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
A multi-repeat adhesin of the phytopathogen, Pectobacterium atrosepticum, is secreted by a Type I pathway and is subject to complex regulation involving a non-canonical diguanylate cyclase
Perez-Mendoza, D., Coulthurst, S. J., Humphris, S., Campbell, E., Welch, M., Toth, I. K. & Salmond, G. P. C., Nov 2011, In: Molecular Microbiology. 82, 3, p. 719-733 15 p.Research output: Contribution to journal › Article › peer-review
44 Citations (Scopus) -
A multiscale mathematical model of tumour invasive growth
Peng, L., Trucu, D., Lin, P., Thompson, A. & Chaplain, M. A. J., Mar 2017, In: Bulletin of Mathematical Biology. 79, 3, p. 389-429 41 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile18 Citations (Scopus)191 Downloads (Pure) -
A multiscale moving boundary model arising in cancer invasion
Trucu, D., Lin, P., Chaplain, M. A. J. & Wang, Y., 2013, In: Multiscale Modeling and Simulation: A SIAM Interdisciplinary Journal. 11, 1, p. 309-335 27 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
A multispecialty study of determining the possibility of pregnancy and the documentation of pregnancy status in surgical patients: a cause for concern?
Ibrahim, I., Ibrahim, B., Yong, G. L., Coats, M., Vujovic, Z. & Wilson, M. S. J., 1 Nov 2018, In: Scottish Medical Journal. 63, 4, p. 108-112 5 p.Research output: Contribution to journal › Article › peer-review
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A mutant O-GlcNAcase enriches Drosophila developmental regulators
Selvan, N., Williamson, R., Mariappa, D., Campbell, D. G., Gourlay, R., Ferenbach, A. T., Aristotelous, T., Hopkins-Navratilova, I., Trost, M. & van Aalten, D. M. F., Aug 2017, In: Nature Chemical Biology. 13, 8, p. 882-887 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Citations (Scopus)215 Downloads (Pure) -
A mutual health service in Scotland: Do we understand fully the leadership implications?
Howieson, B. & Fenwick, C., Jul 2014, In: Leadership in Health Services. 27, 3, p. 193-203 11 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer's Disease
Pickett, E. K., Herrmann, A. G., McQueen, J., Abt, K., Dando, O., Tulloch, J., Jain, P., Dunnett, S., Sohrabi, S., Fjeldstad, M. P., Calkin, W., Murison, L., Jackson, R. J., Tzioras, M., Stevenson, A., d'Orange, M., Hooley, M., Davies, C., Colom-Cadena, M., Anton-Fernandez, A. & 10 others, , 10 Dec 2019, In: Cell Reports. 29, 11, p. 3592-3604.e5Research output: Contribution to journal › Article › peer-review
Open AccessFile24 Citations (Scopus)81 Downloads (Pure) -
Anabolic resistance does not explain sarcopenia in patients with type 2 diabetes mellitus, compared with healthy controls, despite reduced mTOR pathway activity
Cuthbertson, D. J., Babraj, J., Leese, G. & Siervo, M., Dec 2017, In: Clinical Nutrition. 36, 6, p. 1716-1719 4 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
An activatable cancer-targeted hydrogen peroxide probe for photoacoustic and fluorescence imaging
Weber, J., Bollepalli, L., Belenguer, A. M., Antonio, M. D., De Mitri, N., Joseph, J., Balasubramanian, S., Hunter, C. A. & Bohndiek, S. E., 15 Oct 2019, In: Cancer Research. 79, 20, p. 5407-5417 11 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
An active DNA-based nanoprobe for photoacoustic pH imaging
Baumann, K. N., Fux, A. C., Joseph, J., Bohndiek, S. E. & Hernández-Ainsa, S., 2018, In: Chemical Communications. 54, 72, p. 10176-10178 3 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)14 Downloads (Pure) -
An acute transfusion reaction
Webb, C., Norris, A. & Hands, K., 1 Feb 2018, In: Clinical Medicine - Journal of the Royal College of Physicians of London. 18, 1, p. 95-97 3 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
An adaptive IEEE 802.15.4 MAC layer transmission scheme for applications with heterogeneous traffic
Zhou, Y., He, J., Chen, K., Tang, Z. & Li, Y., Dec 2013, In: Information: An Interdisciplinary Journal in English, Japanese and Chinese . 16, 12 A, p. 8451-8456 6 p.Research output: Contribution to journal › Article › peer-review
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Anaesthesia for laryngo-tracheal surgery, including tubeless field techniques
Pearson, K. L. & McGuire, B. E., 1 Jul 2017, In: BJA Education. 17, 7, p. 242-248 7 p.Research output: Contribution to journal › Article › peer-review
7 Citations (Scopus) -
Analgesic tone conferred by constitutively active mu opioid receptors in mice lacking beta-arrestin 2
Lam, H., Maga, M., Pradhan, A., Evans, C. J., Maidment, N. T., Hales, T. G. & Walwyn, W., 12 Apr 2011, In: Molecular Pain. 7, p. - 10 p., 24.Research output: Contribution to journal › Article › peer-review
19 Citations (Scopus) -
An algorithm recommendation for the pharmacological management of allergic rhinitis in the UK: a consensus statement from an expert panel
Lipworth, B., Newton, J., Ram, B., Small, I. & Schwarze, J., 23 Jan 2017, In: NPJ Primary Care Respiratory Medicine. 27, p. 1-8 8 p., 3.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)179 Downloads (Pure) -
Análisis de la formación y el ámbito de práctica de los médicos de atención primaria en Inglaterra, Alemania y España
Glonti, K., Struckmann, V., Alconada, A., Pettigrew, L. M., Hernandez-Santiago, V., Minue, S., Risso-Gill, I., McKee, M. & Legido-Quigley, H., Mar 2019, In: Gaceta Sanitaria. 33, 2, p. 148-155 8 p.Research output: Contribution to journal › Article › peer-review
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An Alternative Genealogy for Global Capitalism: The Rhine Becomes an Inland Sea 1792-1815
Livesey, J., 1 Nov 2019, In: Critical Historical Studies. 6, 2, p. 223-245 23 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Analyses of groundwater flow and plant evapotranspiration in a vegetated soil slope
Leung, A. K. & Ng, C. W. W., Dec 2013, In: Canadian Geotechnical Journal. 50, 12, p. 1204-1218 15 p.Research output: Contribution to journal › Article › peer-review
44 Citations (Scopus) -
Analysing trajectories of a longitudinal exposure: a causal perspective on common methods in lifecourse research
Gadd, S. C., Tennant, P. W. G., Heppenstall, A. J., Boehnke, J. & Gilthorpe, M. S., 4 Dec 2019, In: PLoS ONE. 14, 12, p. 1-12 12 p., e0225217.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)76 Downloads (Pure) -
Analysis for Time Discrete Approximations of Blow-up Solutions of Semilinear Parabolic Equations
Kyza, I. & Makridakis, C., 2011, In: SIAM Journal on Numerical Analysis. 49, 1, p. 405-426 22 p.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus) -
Analysis of > 1000 single nucleotide polymorphisms in geographically matched samples of landrace and wild barley indicates secondary contact and chromosome-level differences in diversity around domestication genes
Russell, J., Dawson, I. K., Flavell, A. J., Steffenson, B., Weltzien, E., Booth, A., Ceccarelli, S., Grando, S. & Waugh, R., 2011, In: New Phytologist. 191, 2, p. 564-578 15 p.Research output: Contribution to journal › Article › peer-review
56 Citations (Scopus) -
Analysis of a continuous finite element method for H(curl,div)-elliptic interface problem
Duan, H., Lin, P. & Tan, R. C. E., 2013, In: Numerische Mathematik. p. 1-37 37 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
Analysis of a model for banded vegetation patterns in semi-arid environments with nonlocal dispersal
Eigentler, L. & Sherratt, J. A., Sep 2018, In: Journal of Mathematical Biology. 77, 3, p. 739-763 25 p.Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus) -
Analysis of chain saw lubricating oils commonly used in Thailand's southern border provinces for forensic science purpose
Choodum, A., Tripuwanard, K. & Daeid, N. N., Aug 2014, In: Forensic Science International. 241, p. 60-68 9 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Analysis of Conformational Changes in the DNA Junction-Resolving Enzyme T7 Endonuclease I on Binding a Four-Way Junction Using EPR
Freeman, A. D. J., Ward, R., El Mkami, H., Lilley, D. M. J. & Norman, D. G., 22 Nov 2011, In: Biochemistry. 50, 46, p. 9963-9972 10 p.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus)