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  • 2020
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Author

  • Brian Lipworth
52 Citations (Scopus)

Airway dysfunction in nasal polyposis: a spectrum of asthmatic disease?

Williamson, P. A., Vaidyanathan, S., Clearie, K., Barnes, M. & Lipworth, B. J., Oct 2011, In : Clinical and Experimental Allergy. 41, 10, p. 1379-1385 7 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Allopurinol in Patients with Pulmonary Hypertension Associated with Chronic Lung Disease

Liu Shiu Cheong, P. S. K., Lipworth, B. J., Weir-McCall, J. R., Houston, J. G. & Struthers, A. D., 25 Aug 2020, In : International Journal of Chronic Obstructive Pulmonary Disease. 2020, 15, p. 2015-2024 10 p.

Research output: Contribution to journalArticle

Open Access
File
9 Downloads (Pure)

An algorithm recommendation for the pharmacological management of allergic rhinitis in the UK: a consensus statement from an expert panel

Lipworth, B., Newton, J., Ram, B., Small, I. & Schwarze, J., 23 Jan 2017, In : NPJ Primary Care Respiratory Medicine. 27, p. 1-8 8 p., 3.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
158 Downloads (Pure)

Anti-inflammatory reliever therapy for asthma

Lipworth, B., Chan, R. & RuiWen Kuo, C., Jan 2020, In : Annals of Allergy, Asthma & Immunology. 124, 1, p. 13-15 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Assessment of small-airways disease using alveolar nitric oxide and impulse oscillometry in asthma and COPD

Williamson, P. A., Clearie, K., Menzies, D., Vaidyanathan, S. & Lipworth, B. J., Apr 2011, In : Lung. 189, 2, p. 121-129 9 p.

Research output: Contribution to journalArticle

65 Citations (Scopus)

Asthma Step-Down Strategies: Perhaps the Patient Should Decide?

Lipworth, B. & Israel, E., Mar 2018, In : The Journal of Allergy and Clinical Immunology: In Practice. 6, 2, p. 644-645 2 p.

Research output: Contribution to journalArticle

Open Access
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137 Downloads (Pure)

Benefits of glycopyrrolate/formoterol fumarate metered dose inhaler (GFF MDI) in improving lung function and reducing exacerbations in patients with moderate-to-very severe COPD: a pooled analysis of the PINNACLE studies

Martinez, F. J., Lipworth, B. J., Rabe, K. F., Collier, D. J., Ferguson, G. T., Sethi, S., Feldman, G. J., O'Brien, G., Jenkins, M. & Reisner, C., 25 May 2020, In : Respiratory Research. 21, 1, p. 1-14 14 p., 128.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
16 Downloads (Pure)

Bronchoprotective tolerance with indacaterol is not modified by concomitant tiotropium in persistent asthma

Jabbal, S., Manoharan, A. & Lipworth, B. J., Oct 2017, In : Clinical and Experimental Allergy. 47, 10, p. 1239-1245 7 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
179 Downloads (Pure)

Cardiopulmonary interactions with beta-blockers and inhaled therapy in COPD

Jabbal, S., Anderson, W., Short, P., Morrison, A., Manoharan, A. & Lipworth, B. J., Dec 2017, In : QJM : an International Journal of Medicine. 110, 12, p. 785-792 8 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
161 Downloads (Pure)

Comparative lung bioavailability of fluticasone/salmeterol via a breath-actuated spacer and conventional plastic spacers

Nair, A., McKinlay, L., Williamson, P., Short, P., Burns, P. & Lipworth, B. J., Apr 2011, In : European Journal of Clinical Pharmacology. 67, 4, p. 355-363 9 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Comparison of bronchodilator response in patients with asthma and healthy subjects using spirometry and oscillometry

Nair, A., Ward, J. & Lipworth, B. J., Oct 2011, In : Annals of Allergy, Asthma & Immunology. 107, 4, p. 317-322 6 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Current appraisal of single inhaler triple therapy in COPD

Lipworth, B., Kuo, R. W. & Jabbal, S., 28 Sep 2018, In : International Journal of Chronic Obstructive Pulmonary Disease. 13, 13, p. 3003-3009 7 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
155 Downloads (Pure)

Disconnection of pulmonary and systemic arterial stiffness in COPD

Weir-McCall, J. R., Liu-Shiu-Cheong, P. S., Struthers, A. D., Lipworth, B. J. & Houston, J. G., 28 May 2018, In : International Journal of Chronic Obstructive Pulmonary Disease. 13, p. 1755-1765 11 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
135 Downloads (Pure)

Effect of beta blockers in treatment of chronic obstructive pulmonary disease: a retrospective cohort study

Short, P. M., Lipworth, S. I. W., Elder, D. H. J., Schembri, S. & Lipworth, B. J., 10 May 2011, In : BMJ. 342, p. - 9 p., d2549.

Research output: Contribution to journalArticle

203 Citations (Scopus)
Open Access
File
2 Citations (Scopus)
180 Downloads (Pure)

Effects of intravenous and oral β-blockade in persistent asthmatics controlled on inhaled corticosteroids

Short, P. M., Anderson, W. J., Williamson, P. A. & Lipworth, B. J., Feb 2014, In : Heart (British Cardiac Society). 100, 3, p. 219-223 5 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19

Herold, T., Jurinovic, V., Arnreich, C., Lipworth, B. J., Hellmuth, J. C., von Bergwelt-Baildon, M., Klein, M. & Weinberger, T., Jul 2020, In : Journal of Allergy and Clinical Immunology. 146, 1, p. 128-136.e4 13 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Erratum to: Comparative lung bioavailability of fluticasone/salmeterol via a breath-actuated spacer and conventional plastic spacers

Nair, A., McKinlay, L., Williamson, P., Short, P., Burns, P. & Lipworth, B. J., Jun 2017, In : European Journal of Clinical Pharmacology. 73, 6, p. 793-793 1 p.

Research output: Contribution to journalArticle

Glycopyrrolate/formoterol fumarate metered dose inhaler for maintenance-naïve patients with chronic obstructive pulmonary disease: a post-hoc analysis of the randomized PINNACLE trials

Zheng, J., Xu, J-F., Jenkins, M., Assam, P. N., Wang, L. & Lipworth, B. J., 12 Mar 2020, In : Respiratory Research. 21, 1, p. 1-10 10 p., 69.

Research output: Contribution to journalArticle

Open Access
File
29 Downloads (Pure)

Glycopyrrolate/formoterol fumarate metered dose inhaler improves lung function versus monotherapies in GOLD category a patients with COPD: Pooled data from the phase III PINNACLE studies

Martinez, F. J., Rabe, K. F., Lipworth, B. J., Arora, S., Jenkins, M., Martin, U. J. & Reisner, C., 2020, In : International Journal of COPD. 15, p. 99-106 8 p.

Research output: Contribution to journalArticle

Open Access
File
38 Downloads (Pure)

Impact of long-acting bronchodilators and exposure to inhaled corticosteroids on mortality in COPD: a real-life retrospective cohort study

Manoharan, A., Short, P. M., Anderson, W. J. & Lipworth, B. J., Oct 2014, In : Lung. 192, 5, p. 649-652 4 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Improved lung function and patient-reported outcomes with co-suspension delivery technology glycopyrrolate/formoterol fumarate metered dose inhaler in COPD: a randomized Phase III study conducted in Asia, Europe, and the USA

Lipworth, B. J., Collier, D. J., Gon, Y., Zhong, N., Nishi, K., Chen, R., Arora, S., Maes, A., Siddiqui, S., Reisner, C. & Martin, U. J., 26 Sep 2018, In : International Journal of Chronic Obstructive Pulmonary Disease. 13, p. 2969-2984 16 p.

Research output: Contribution to journalArticle

Open Access
File
16 Citations (Scopus)
128 Downloads (Pure)

Influence of β2-adrenergic receptor polymorphism on methacholine hyperresponsiveness in asthmatic patients

Manoharan, A., Anderson, W. J. & Lipworth, B. J., Mar 2013, In : Annals of Allergy, Asthma & Immunology. 110, 3, p. 161-164 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Inhaled and Systemic Corticosteroid Response in Severe Asthma Assessed by Alveolar Nitric Oxide: a randomised crossover pilot study of add-on therapy

Williamson, P. A., Short, P. M., Vaidyanathan, S. & Lipworth, B. J., Jan 2013, In : British Journal of Clinical Pharmacology. 75, 1, p. 93-102 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Inhaled corticosteroid dose-response in asthma: Should we measure inflammation?

Anderson, W. J., Short, P., Jabbal, S. & Lipworth, B., Feb 2017, In : Annals of Allergy, Asthma & Immunology. 118, 2, p. 179-185 6 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
146 Downloads (Pure)

Left Ventricular Hypertrophy in COPD Without Hypoxemia: The Elephant in the Room?

Anderson, W. J., Lipworth, B. J., Rekhraj, S., Struthers, A. D. & George, J., Jan 2013, In : Chest. 143, 1, p. 91-97 7 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Making simple things complicated using anti-inflammatory reliever therapy

Lipworth, B., Kuo, C. R. & Chan, R., 30 Apr 2020, In : European Respiratory Journal. 55, 4, 2000267.

Research output: Contribution to journalArticle

Nasal AMP and histamine challenge within and outside the pollen season in patients with seasonal allergic rhinitis

Vaidyanathan, S., Williamson, P., Clearie, K., Morrison, A. & Lipworth, B., Jan 2011, In : Journal of Allergy and Clinical Immunology. 127, 1, p. 173-203.e3 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Pharmacokinetic and pharmacodynamic comparison of hydrofluoroalkane and chlorofluorocarbon formulations of budesonide

Clearie, K. L., Williamson, P. A., Meldrum, K., Gillen, M., Carlsson, L-G., Carlholm, M., Ekelund, J. & Lipworth, B. J., Apr 2011, In : British Journal of Clinical Pharmacology. 71, 4, p. 504-513 10 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Prescribing of β-adrenoceptor antagonists in asthma: an observational study

Morales, D. R., Guthrie, B., Lipworth, B. J., Donnan, P. T. & Jackson, C., Jun 2011, In : Thorax. 66, 6, p. 502-507 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Proof of concept evaluation of trough airway hyper-responsiveness following regular racemic or levosalbutamol in genotype-stratified steroid-treated persistent asthmatic patients

Anderson, W. J., Short, P. M., Williamson, P. A., Morrison, A. E., Palmer, C., Tavendale, R. & Lipworth, B. J., 1 Jan 2014, In : Clinical Science. 126, 1, p. 75-83 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Proof of concept study to evaluate step-down therapy with inhaled corticosteroid alone or additive therapy on surrogate inflammatory markers in asthma

McKinlay, L., Williamson, P. A., Short, P. M., Fardon, T. & Lipworth, B. J., Jan 2011, In : British Journal of Clinical Pharmacology. 71, 1, p. 128-131 4 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Pulmonary and systemic arterial stiffness are disconnected in COPD

Weir-McCall, J., Liu Shiu Cheong, P., Struthers, A., Lipworth, B. & Houston, J., 28 May 2018, In : International Journal of Chronic Obstructive Pulmonary Disease. 13, p. 1755-1765 16 p.

Research output: Contribution to journalArticle

Pulmonary arterial stiffening in COPD and its implications for right ventricular remodelling.

Weir-McCall, J. R., Liu Shiu Cheong, P. S. K., Struthers, A. D., Lipworth, B. J. & Houston, J. G., Aug 2018, In : European Radiology. 28, 8, p. 3464-3472 9 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
216 Downloads (Pure)

Randomised Placebo-controlled Trial to Evaluate Chronic Dosing Effects of Propranolol in Asthma

Short, P. M., Williamson, P. A., Anderson, W. J. & Lipworth, B. J., 15 Jun 2013, In : American Journal of Respiratory and Critical Care Medicine. 187, 12, p. 1308-1314 7 p.

Research output: Contribution to journalArticle

40 Citations (Scopus)
Open Access
File
42 Downloads (Pure)

Relationship of large and small airway response with inhaled corticosteroid to asthma control

Manoharan, A., Anderson, W. J. & Lipworth, B. J., Aug 2013, In : Annals of Allergy, Asthma & Immunology. 111, 2, p. 140-142 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Relationships between airway hyperresponsiveness, inflammation, and calibre in asthma

Short, P. M., Lipworth, S. I. W. & Lipworth, B. J., Dec 2011, In : Lung. 189, 6, p. 493-497 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
Open Access
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27 Citations (Scopus)
289 Downloads (Pure)
41 Citations (Scopus)
Open Access
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3 Citations (Scopus)
146 Downloads (Pure)

Small airway dysfunction is associated with poorer asthma control

Manoharan, A., Anderson, W. J., Lipworth, J., Ibrahim, I. & Lipworth, B. J., Nov 2014, In : European Respiratory Journal. 44, 5, p. 1353-1355 3 p.

Research output: Contribution to journalArticle

Open Access
File
30 Citations (Scopus)
128 Downloads (Pure)

Supervised step-down of inhaled corticosteroids in the community: an observational study

Clearie, K. L., Jackson, C. M., Fardon, T. C., Williamson, P. A., Vaidyanathan, S., Burns, P. & Lipworth, B. J., Apr 2011, In : Respiratory Medicine. 105, 4, p. 558-565 8 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Tadalafil in patients with chronic obstructive pulmonary disease: a randomised, double-blind, parallel-group, placebo-controlled trial

Goudie, A. R., Lipworth, B. J., Hopkinson, P. J., Wei, L. & Struthers, A. D., Apr 2014, In : The Lancet Respiratory Medicine. 2, 4, p. 293-300 8 p.

Research output: Contribution to journalArticle

Open Access
File
55 Citations (Scopus)
157 Downloads (Pure)

Tailored second-line therapy in asthmatic children with the Arg16 genotype

Lipworth, B. J., Basu, K., Donald, H. P., Tavendale, R., MacGregor, D. F., Ogston, S. A., Palmer, C. N. A. & Mukhopadhyay, S., Apr 2013, In : Clinical Science. 124, 8, p. 521-528 8 p.

Research output: Contribution to journalArticle

53 Citations (Scopus)