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AluY-mediated germline deletion, duplication and somatic stem cell reversion in UBE2T defines a new subtype of Fanconi anemia
Virts, E. L., Jankowska, A., Mackay, C., Glaas, M. F., Wiek, C., Kelich, S. L., Lottmann, N., Kennedy, F. M., Marchal, C., Lehnert, E., Scharf, R. E., Dufour, C., Lanciotti, M., Farruggia, P., Santoro, A., Savasan, S., Scheckenbach, K., Schipper, J., Wagenmann, M., Lewis, T. & 12 others, , 15 Sep 2015, In: Human Molecular Genetics. 24, 18, p. 5093-5108 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile45 Citations (Scopus)105 Downloads (Pure) -
A mechanical signal transmitted by the flagellum controls signalling in Bacillus subtilis
Cairns, L. S., Marlow, V. L., Bissett, E., Ostrowski, A. & Stanley-Wall, N. R., Oct 2013, In: Molecular Microbiology. 90, 1, p. 6-21 16 p.Research output: Contribution to journal › Article › peer-review
83 Citations (Scopus) -
A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic dermatitis
Naeem, A. S., Tommasi, C., Cole, C., Brown, S. J., Zhu, Y., Way, B., Willis Owen, S. A. G., Moffatt, M., Cookson, W. O., Harper, J. I., Di, W. L., Brown, S. J., Reinheckel, T. & O'Shaughnessy, R. F. L., Apr 2017, In: Journal of Allergy and Clinical Immunology. 139, 4, p. 1228-1241 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)217 Downloads (Pure) -
A MEMS-based electronic capsule for time controlled drug delivery in the alimentary canal
Zhuang, Y., Hou, W., Zheng, X., Wang, Z., Zheng, J., Pi, X., Cui, J., Jiang, Y., Qian, S. & Peng, C., 10 Sep 2011, In: Sensors and Actuators A - Physical. 169, 1, p. 211-216 6 p.Research output: Contribution to journal › Article › peer-review
10 Citations (Scopus) -
A meta-ethnography of the facilitators and barriers to successful implementation of patient complaints processes in health-care settings
Scott, D. & Grant, S. M., Apr 2018, In: Health Expectations. 21, 2, p. 508-517 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)207 Downloads (Pure) -
A metagenetics approach to determine the diversity and distribution of cyst nematodes at the level of the country, the field and the individual
Eves-van den Akker, S., Lilley, C. J., Reid, A., Pickup, J., Anderson, E., Cock, P. J. A., Blaxter, M., Urwin, P. E., Jones, J. T. & Blok, V. C., Dec 2015, In: Molecular Ecology. 24, 23, p. 5842-5851 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)124 Downloads (Pure) -
A method for automatic segmentation and splitting of hyperspectral images of raspberry plants collected in field conditions
Williams, D., Britten, A., McCallum, S., Jones, H., Aitkenhead, M., Karley, A., Loades, K., Prashar, A. & Graham, J., 1 Nov 2017, In: Plant Methods. 13, p. 1-12 12 p., 74.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)175 Downloads (Pure) -
A methodological approach to assess the hazard of underground cavities subjected to environmental weathering
Castellanza, R., Lollino, P. & Ciantia, M., Dec 2018, In: Tunnelling and Underground Space Technology. 82, p. 278-292 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)43 Downloads (Pure) -
A Micropower Miniature Piezoelectric Actuator for Implantable Middle Ear Hearing Device
Wang, Z., Mills, R., Luo, H., Zheng, X., Hou, W., Wang, L., Brown, S. I. & Cuschieri, A., Feb 2011, In: IEEE Transactions on Biomedical Engineering. 58, 2, p. 452-458 7 p.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus) -
Amine Containing Analogs of Sulindac for Cancer Prevention
Mathew, B., Hobrath, J. V., Connelly, M. C., Guy, R. K. & Reynolds, R. C., 31 Jan 2018, In: Open Medicinal Chemistry Journal. 12, p. 1-12 12 p.Research output: Contribution to journal › Article › peer-review
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Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice
Loftus, R. M., Assmann, N., Kedia-Mehta, N., O'Brien, K. L., Garcia, A., Gillespie, C., Hukelmann, J. L., Oefner, P. J., Lamond, A. I., Gardiner, C. M., Dettmer, K., Cantrell, D. A., Sinclair, L. V. & Finlay, D. K., 14 Jun 2018, In: Nature Communications. 9, 1, p. 1-15 15 p., 2341.Research output: Contribution to journal › Article › peer-review
Open AccessFile62 Citations (Scopus)177 Downloads (Pure) -
Amino acid neurotoxins in feathers of the Lesser Flamingo, Phoeniconaias minor
Metcalf, J. S., Banack, S. A., Kotut, K., Krienitz, L. & Codd, G. A., Jan 2013, In: Chemosphere. 90, 2, p. 835-839 5 p.Research output: Contribution to journal › Article › peer-review
24 Citations (Scopus) -
A mixed-methods feasibility study protocol to assess the communication behaviours within the dental health professional-parent-child triad in a general dental practice setting
Yuan, S., Humphris, G. M., Ross, A., MacPherson, L., Zhou, Y. & Freeman, R., 13 Aug 2018, In: Pilot and Feasibility Studies. 4, p. 1-9 9 p., 136.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)177 Downloads (Pure) -
A model based criterion for gene expression calls using RNA-seq data
Wagner, G. P., Kin, K. & Lynch, V. J., Sep 2013, In: Theory in Biosciences. 132, 3, p. 159-164 6 p.Research output: Contribution to journal › Article › peer-review
77 Citations (Scopus) -
A model for dynamic reconfiguration in service-oriented architectures
Fiadeiro, J. L. & Lopes, A., 1 May 2013, In: Software and Systems Modeling. 12, 2, p. 349-367 19 p.Research output: Contribution to journal › Article › peer-review
26 Citations (Scopus) -
A model of consultation in prostate cancer care: evidence from a systematic review
Paterson, C. & Nabi, G., 2017, In: Cancer Nursing. 40, 4, p. 276-288 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile13 Citations (Scopus)401 Downloads (Pure) -
A model of the transformative journey into reflexivity: an exploration into students' experiences of critical reflection
Shaw, R., 15 Feb 2013, In: Reflective Practice. 14, 3, p. 319-335 17 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
A molecular explanation for the recessive nature of parkin-linked Parkinson's disease
Spratt, D. E., Julio Martinez-Torres, R., Noh, Y. J., Mercier, P., Manczyk, N., Barber, K. R., Aguirre, J. D., Burchell, L., Purkiss, A., Walden, H. & Shaw, G. S., 1 Jan 2013, In: Nature Communications. 4, 12 p., 1983.Research output: Contribution to journal › Article › peer-review
88 Citations (Scopus) -
A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors
Harrison, J. R., Brand, S., Smith, V., Robinson, D. A., Thompson, S., Smith, A., Davies, K., Mok, N., Torrie, L. S., Collie, I., Hallyburton, I., Norval, S., Simeons, F. R. C., Stojanovski, L., Frearson, J. A., Brenk, R., Wyatt, P. G., Gilbert, I. H. & Read, K. D., 12 Sep 2018, In: Journal of Medicinal Chemistry. 61, 18, p. 8374–8389 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile19 Citations (Scopus)209 Downloads (Pure) -
A monovalent ion in the DNA binding interface of the eukaryotic junction-resolving enzyme GEN1
Liu, Y., Freeman, A. D. J., Déclais, A-C. & Lilley, D. M. J., 16 Nov 2018, In: Nucleic Acids Research. 46, 20, p. 11089-11098 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)117 Downloads (Pure) -
"A Morning Since Eight of Just Pure Grill": A Multischool Qualitative Study of Student Abuse
Rees, C. E. & Monrouxe, L. V., Nov 2011, In: Academic Medicine: Journal of the Association of American Medical Colleges. 86, 11, p. 1374-1382 9 p.Research output: Contribution to journal › Article › peer-review
46 Citations (Scopus) -
A Morphological identification cell cytotoxicity assay using cytoplasm-localized fluorescent probe (CLFP) to distinguish living and dead cells
Lai, F., Shen, Z., Wen, H., Chen, J., Zhang, X., Lin, P., Yin, D., Cui, H. & Chen, X., 8 Jan 2017, In: Biochemical and Biophysical Research Communications. 482, 2, p. 257-263 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)409 Downloads (Pure) -
AMP-activated protein kinase: a cellular energy sensor with a key role in metabolic disorders and in cancer
Hardie, D. G., Feb 2011, In: Biochemical Society Transactions. 39, p. 1-13 13 p.Research output: Contribution to journal › Article › peer-review
123 Citations (Scopus) -
AMP-activated protein kinase (AMPK)α2 plays a role in determining the cellular fate of glucose in insulin-resistant mouse skeletal muscle
Lee-Young, R. S., Bonner, J. S., Mayes, W. H., Iwueke, I., Barrick, B. A., Hasenour, C. M., Kang, L. & Wasserman, D. H., Mar 2013, In: Diabetologia. 56, 3, p. 608-617 10 p.Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus) -
AMP-activated protein kinase activator A-769662 increases intracellular calcium and ATP release from astrocytes in an AMPK-independent manner
Vlachaki Walker, J. M., Robb, J. L., Cruz, A. M., Malhi, A., Weightman Potter, P. G., Ashford, M. L. J., McCrimmon, R. J., Ellacott, K. L. J. & Beall, C., 21 Apr 2017, In: Diabetes, Obesity & Metabolism. 19, 7, p. 997-1005 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)295 Downloads (Pure) -
AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study
Boyle, J. G., Logan, P. J., Jones, G. C., Small, M., Sattar, N., Connell, J. M. C., Cleland, S. J. & Salt, I. P., 2011, In: Diabetologia. 54, 7, p. 1799-1809 11 p.Research output: Contribution to journal › Article › peer-review
54 Citations (Scopus) -
AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation
Gowans, G. J., Hawley, S. A., Ross, F. A. & Hardie, D. G., 1 Oct 2013, In: Cell Metabolism. 18, 4, p. 556-566 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile275 Citations (Scopus)163 Downloads (Pure) -
AMPK: a target for drugs and natural products with effects on both diabetes and cancer
Hardie, D. G., Jul 2013, In: Diabetes. 62, 7, p. 2164-2172 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile264 Citations (Scopus)138 Downloads (Pure) -
AMPK: opposing the metabolic changes in both tumour cells and inflammatory cells?
Dandapani, M. & Hardie, D. G., Apr 2013, In: Biochemical Society Transactions. 41, 2, p. 687-693 7 p.Research output: Contribution to journal › Article › peer-review
34 Citations (Scopus) -
AMPK dilates resistance arteries via activation of SERCA and BKCa channels in smooth muscle
Schneider, H., Schubert, K. M., Blodow, S., Kreutz, C-P., Erdogmus, S., Wiedenmann, M., Qiu, J., Fey, T., Ruth, P., Lubomirov, L. T., Pfitzer, G., Mederos y Schnitzler, M., Hardie, D. G., Gudermann, T. & Pohl, U., Jul 2015, In: Hypertension. 66, 1, p. 108-116 9 p.Research output: Contribution to journal › Article › peer-review
30 Citations (Scopus) -
AMPK modulates glucose-sensing in insulin-secreting cells by altered phosphotransfer to KATP channels
Beall, C., Watterson, K. R., McCrimmon, R. J. & Ashford, M. L. J., Jun 2013, In: Journal of Bioenergetics and Biomembranes. 45, 3, p. 229-241 13 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
AMPKα1: a glucose sensor that controls CD8 T-cell memory
Rolf, J., Zarrouk, M., Finlay, D. K., Foretz, M., Viollet, B. & Cantrell, D. A., Apr 2013, In: European Journal of Immunology. 43, 4, p. 889-896 8 p.Research output: Contribution to journal › Article › peer-review
138 Citations (Scopus) -
Amputation-free survival in 17,353 people at high risk for foot ulceration in diabetes: a national observational study
Scottish Diabetes Research Network Epidemiology Group, Vadiveloo, T., Jeffcoate, W., Donnan, P. T., Colhoun, H. C., McGurnaghan, S., Wild, S., McCrimmon, R. & Leese, G. P., Dec 2018, In: Diabetologia. 61, 12, p. 2590-2597 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Citations (Scopus)193 Downloads (Pure) -
A Multicellular Model of Intestinal Crypt Buckling and Fission
Almet, A. A., Hughes, B. D., Landman, K. A., Näthke, I. S. & Osborne, J. M., Feb 2018, In: Bulletin of Mathematical Biology. 80, 2, p. 335-359 25 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)228 Downloads (Pure) -
A multi-centre, parallel group superiority trial of silk therapeutic clothing compared to standard care for the management of eczema in children (CLOTHES Trial): study protocol for a randomised controlled trial
Harrison, E. F., Haines, R. H., Cowdell, F., Sach, T. H., Dean, T., Pollock, I., Burrows, N. P., Buckley, H., Batchelor, J., Williams, H. C., Lawton, S., Brown, S. J., Bradshaw, L. E., Ahmed, A., Montgomery, A. A., Mitchell, E. J. & Thomas, K. S., 2 Sep 2015, In: Trials. 16, 12 p., 390.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)173 Downloads (Pure) -
A Multi-disciplinary Approach to the Archaeological Investigation of a Bedrock-Dominated Shallow-Marine Landscape: An example from the Bay of Firth, Orkney, UK
Bates, M. R., Nayling, N., Bates, R., Dawson, S., Huws, D. & Wickham-Jones, C., Mar 2013, In: International Journal of Nautical Archaeology. 42, 1, p. 24-43 20 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
A multifaceted approach to identify non-specific enzyme inhibition: Application to Mycobacterium tuberculosis shikimate kinase
Alturki, M. S., Fuanta, N. R., Jarrard, M. A., Hobrath, J. V., Goodwin, D. C., Rants'o, T. A. & Calderón, A. I., 15 Feb 2018, In: Bioorganic and Medicinal Chemistry Letters. 28, 4, p. 802-808 7 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)160 Downloads (Pure) -
A Multifunctional Protease Inhibitor To Regulate Endolysosomal Function
van Kasteren, S. I., Berlin, I., Colbert, J. D., Keane, D., Ovaa, H. & Watts, C., Nov 2011, In: ACS Chemical Biology. 6, 11, p. 1198-1204 7 p.Research output: Contribution to journal › Article › peer-review
16 Citations (Scopus) -
A multigenic model to predict risk of ischemic stroke in subjects with type 2 diabetes
Pola, R., Kimber, C. H., Giarretta, I., Doney, A., Morris, A. M., Gaetani, E. & Palmer, C. N., Jun 2011, In: Atherosclerosis. Supplements. 12, 1, p. 127-127 1 p.Research output: Contribution to journal › Article › peer-review
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A multiprotein binding interface in an intrinsically disordered region of the tumor suppressor protein interferon regulatory factor-1
Narayan, V., Halada, P., Hernychová, L., Chong, Y. P., Žáková, J., Hupp, T. R., Vojtesek, B. & Ball, K. L., 22 Apr 2011, In: Journal of Biological Chemistry. 286, 16, p. 14291-14303 13 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
A multi-repeat adhesin of the phytopathogen, Pectobacterium atrosepticum, is secreted by a Type I pathway and is subject to complex regulation involving a non-canonical diguanylate cyclase
Perez-Mendoza, D., Coulthurst, S. J., Humphris, S., Campbell, E., Welch, M., Toth, I. K. & Salmond, G. P. C., Nov 2011, In: Molecular Microbiology. 82, 3, p. 719-733 15 p.Research output: Contribution to journal › Article › peer-review
43 Citations (Scopus) -
A multiscale mathematical model of tumour invasive growth
Peng, L., Trucu, D., Lin, P., Thompson, A. & Chaplain, M. A. J., Mar 2017, In: Bulletin of Mathematical Biology. 79, 3, p. 389-429 41 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile17 Citations (Scopus)178 Downloads (Pure) -
A multiscale moving boundary model arising in cancer invasion
Trucu, D., Lin, P., Chaplain, M. A. J. & Wang, Y., 2013, In: Multiscale Modeling and Simulation: A SIAM Interdisciplinary Journal. 11, 1, p. 309-335 27 p.Research output: Contribution to journal › Article › peer-review
22 Citations (Scopus) -
A multispecialty study of determining the possibility of pregnancy and the documentation of pregnancy status in surgical patients: a cause for concern?
Ibrahim, I., Ibrahim, B., Yong, G. L., Coats, M., Vujovic, Z. & Wilson, M. S. J., 1 Nov 2018, In: Scottish Medical Journal. 63, 4, p. 108-112 5 p.Research output: Contribution to journal › Article › peer-review
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A mutant O-GlcNAcase as a probe to reveal global dynamics of protein O-GlcNAcylation during Drosophila embryonic development
Mariappa, D., Selvan, N., Borodkin, V. S., Alonso, J., Ferenbach, A. T., Shepherd, C., Navratilova, I. H. & Van Aalten, D. M. F., Sep 2015, In: Biochemical Journal. 470, 2, p. 255-262 8 p.Research output: Contribution to journal › Article › peer-review
17 Citations (Scopus) -
A mutant O-GlcNAcase enriches Drosophila developmental regulators
Selvan, N., Williamson, R., Mariappa, D., Campbell, D. G., Gourlay, R., Ferenbach, A. T., Aristotelous, T., Hopkins-Navratilova, I., Trost, M. & van Aalten, D. M. F., Aug 2017, In: Nature Chemical Biology. 13, 8, p. 882-887 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile22 Citations (Scopus)199 Downloads (Pure) -
Anabolic resistance does not explain sarcopenia in patients with type 2 diabetes mellitus, compared with healthy controls, despite reduced mTOR pathway activity
Cuthbertson, D. J., Babraj, J., Leese, G. & Siervo, M., Dec 2017, In: Clinical Nutrition. 36, 6, p. 1716-1719 4 p.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
An active DNA-based nanoprobe for photoacoustic pH imaging
Baumann, K. N., Fux, A. C., Joseph, J., Bohndiek, S. E. & Hernández-Ainsa, S., 2018, In: Chemical Communications. 54, 72, p. 10176-10178 3 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)8 Downloads (Pure) -
An acute transfusion reaction
Webb, C., Norris, A. & Hands, K., 1 Feb 2018, In: Clinical Medicine - Journal of the Royal College of Physicians of London. 18, 1, p. 95-97 3 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
An adaptive IEEE 802.15.4 MAC layer transmission scheme for applications with heterogeneous traffic
Zhou, Y., He, J., Chen, K., Tang, Z. & Li, Y., Dec 2013, In: Information: An Interdisciplinary Journal in English, Japanese and Chinese . 16, 12 A, p. 8451-8456 6 p.Research output: Contribution to journal › Article › peer-review