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• Review article

  Chronic pain in later life: A review of current issues and challenges

  Schofield, P., Clarke, A., Jones, D., Martin, D., McNamee, P. & Smith, B., Aug 2011, In: Aging Health. 7, 4, p. 551-556 6 p.

  Research output: Contribution to journal › Review article › peer-review

  • Chronic Pain
  • Health
  • Pain
  • Population Health
  • Biomedical Research
  18 Citations (Scopus)

• Incidence of iatrogenic opioid dependence or abuse in patients with pain who were exposed to opioid analgesic therapy: a systematic review and meta-analysis

  Higgins, C., Smith, B. & Matthews, K., Jun 2018, In: British Journal of Anaesthesia. 120, 6, p. 1335-1344 10 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Opioid-Related Disorders
  • Opioid Analgesics
  • Meta-Analysis
  • Systematic Reviews
  • Pain
  34 Citations (Scopus)

  178 Downloads (Pure)

• NeuPSIG guidelines on neuropathic pain assessment

  Haanpaa, M., Attal, N., Backonja, M., Baron, R., Bennett, M., Bouhassira, D., Cruccu, G., Hansson, P., Haythornthwaite, J. A., Iannetti, G. D., Jensen, T. S., Kauppila, T., Nurmikko, T. J., Rice, A. S. C., Rowbotham, M., Serra, J., Sommer, C., Smith, B. H. & Treede, R-D., Jan 2011, In: Pain. 152, 1, p. 14-27 14 p.

  Research output: Contribution to journal › Review article › peer-review
  650 Citations (Scopus)

• Systematic review and meta-analysis of genetic risk factors for neuropathic pain

  Veluchamy, A., Hébert, H. L., Meng, W., Palmer, C. N. A. & Smith, B. H., May 2018, In: Pain. 159, 5, p. 825-848 24 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Neuralgia
  • Meta-Analysis
  • Systematic Reviews
  • HLA-A Antigens
  • HLA-DQB1 antigen
  17 Citations (Scopus)

  310 Downloads (Pure)
• Letter

  Large-scale discovery of novel genetic causes of developmental disorders

  Deciphering Developmental Disorders (DDD) Study, 12 Mar 2015, In: Nature. 519, 7542, p. 223-228 6 p.

  Research output: Contribution to journal › Letter › peer-review

  • Inborn Genetic Diseases
  • Child
  • Exome
  • Genes
  • Missense Mutation
  512 Citations (Scopus)
• Editorial

  Editorial IV. Managing chronic pain: a clinical challenge: new SIGN guidelines provide a practical evidence-based approach and identify research gaps

  Colvin, L. A., Stein, A. & Smith, B. H., 2014, In: BRITISH JOURNAL OF ANAESTHESIA. 112, 1, p. 9-12 4 p.

  Research output: Contribution to journal › Editorial › peer-review
  2 Citations (Scopus)
• Comment/debate

  Out of Hours: My personal diagnostic delay

  Smith, B. H., 1 Apr 2015, In: British Journal of General Practice. 65, 633, p. 200 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  • Physicians
• Chapter

  Neuropathic pain

  Smith, B. H. & Torrance, N., 1 Jan 2011, Chronic Pain Epidemiology: From Aetiology to Public Health. Croft, P., Blyth, F. M. & van der Windt, D. (eds.). Oxford University Press

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Neuralgia
  • Pain
  • Epidemiology
  • Public Health
  • Population
  2 Citations (Scopus)
• Article

  A classification of chronic pain for ICD-11

  Treede, R-D., Rief, W., Barke, A., Aziz, Q., Bennett, M. I., Benoliel, R., Cohen, M., Evers, S., Finnerup, N. B., First, M. B., Giamberardino, M. A., Kaasa, S., Kosek, E., Lavandʼhomme, P., Nicholas, M., Perrot, S., Scholz, J., Schug, S., Smith, B. H., Svensson, P. & 2 others, Vlaeyen, J. W. S. & Wang, S-J., Jun 2015, In: Pain. 156, 6, p. 1003-1007 5 p.

  Research output: Contribution to journal › Article › peer-review
  665 Citations (Scopus)

• A Genome-Wide Association Study Finds Genetic Associations with Broadly-Defined Headache in UK Biobank (N = 223,773)

  Meng, W., Adams, M. J., Hebert, H. L., Deary, I. J., McIntosh, A. M. & Smith, B. H., Feb 2018, In: EBioMedicine. 28, p. 180-186 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Genome-Wide Association Study
  • Genes
  • Headache
  • Single Nucleotide Polymorphism
  • Tissue
  16 Citations (Scopus)

  204 Downloads (Pure)

• A genome-wide association study provides evidence of sex-specific involvement of Chr1p35.1 (ZSCAN20-TLR12P) and Chr8p23.1 (HMGB1P46) with diabetic neuropathic pain

  Meng, W., Deshmukh, H. A., Donnelly, L. A., Wellcome Trust Case Control Consortium 2, Surrogate Markers for Micro- and Macro-Vascular Hard Endpoints for Innovative Diabetes Tools (SUMMIT) Study Group, Torrance, N., Colhoun, H. M., Palmer, C. N. A. & Smith, B. H., Oct 2015, In: EBioMedicine. 2, 10, p. 1386-1393 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Genome-Wide Association Study
  • Neuralgia
  • Genes
  • Nortriptyline
  • Genetics
  32 Citations (Scopus)

  189 Downloads (Pure)

• A genome-wide association study suggests an association of Chr8p21.3 (GFRA2) with diabetic neuropathic pain

  Meng, W., Deshmukh, H. A., van Zuydam, N. R., Liu, Y., Donnelly, L. A., Zhou, K., Wellcome Trust Case Control Consortium 2, Surrogate Markers for Micro- and Macro-Vascular Hard Endpoints for Innovative Diabetes Tools (SUMMIT) Study Group, Morris, A. D., Colhoun, H. M., Palmer, C. N. A. & Smith, B. H., Mar 2015, In: European Journal of Pain. 19, 3, p. 392-399 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Genome-Wide Association Study
  • Neuralgia
  • Prescriptions
  • Datasets
  • Diabetes Complications
  38 Citations (Scopus)

  226 Downloads (Pure)

• Association between cognition and gene polymorphisms involved in thrombosis and haemostasis

  Quinn, T. J., Alghamdi, J., Padmanabhan, S., Porteous, D. J., Smith, B. H., Hocking, L., Deary, I. J., Gallacher, J., Messow, M. & Stott, D. J., 3 Aug 2015, In: Age. 37, 4, 9 p., 80.

  Research output: Contribution to journal › Article › peer-review

  • Hemostasis
  • Single Nucleotide Polymorphism
  • Cognition
  • Thrombosis
  • Plasminogen Inactivators
  2 Citations (Scopus)

• Association of opioid prescribing practices with chronic pain and benzodiazepine co-prescription: a primary care data linkage study

  Torrance, N., Mansoor, R., Wang, H., Gilbert, S., Macfarlane, G. J., Serpell, M., Baldacchino, A., Hales, T. G., Donnan, P., Wyper, G., Smith, B. H. & Colvin, L., Jun 2018, In: British Journal of Anaesthesia. 120, 6, p. 1345-1355 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Benzodiazepines
  • Information Storage and Retrieval
  • Chronic Pain
  • Opioid Analgesics
  • Prescriptions
  17 Citations (Scopus)

  177 Downloads (Pure)

• A study of National Health Service management of chronic osteoarthritis and low back pain

  Hart, O. R., Uden, R. M., McMullan, J. E., Ritchie, M. S., Williams, T. D. & Smith, B. H., 2014, In: Primary Health Care Research and Development. 16, 2, p. 157-166 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • National Health Programs
  • Low Back Pain
  • Osteoarthritis
  • Chronic Pain
  • Primary Health Care
  4 Citations (Scopus)

  186 Downloads (Pure)

• Can large surveys conducted on highly selected populations provide valid information on the epidemiology of common health conditions? An analysis of UK Biobank data on musculoskeletal pain

  Macfarlane, G. J., Beasley, M., Smith, B. H., Jones, G. T. & Macfarlane, T. V., 20 Oct 2015, In: British Journal of Pain. 9, 4, p. 203-212 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Musculoskeletal Pain
  • Epidemiology
  • Pain
  • Health
  • Population
  23 Citations (Scopus)

• Changes in opioid and other analgesic use 1995-2010: repeated cross-sectional analysis of dispensed prescribing for a large geographical population in Scotland

  Ruscitto, A., Smith, B. H. & Guthrie, B., 1 Jan 2015, In: European Journal of Pain. 19, 1, p. 59-66 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Scotland
  • Opioid Analgesics
  • Analgesics
  • Cross-Sectional Studies
  • Population
  69 Citations (Scopus)

• Chronic pain in families: A cross-sectional study of shared social, behavioural, and environmental influences

  Generation Scotland, Campbell, P., Jordan, K. P., Smith, B. & Dunn, K. M., 1 Jan 2018, In: Pain. 159, 1, p. 41-47 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Chronic Pain
  • Cross-Sectional Studies
  • Family Health
  • Scotland
  • Income
  5 Citations (Scopus)

  120 Downloads (Pure)

• Cohort Profile: Genetics of Diabetes Audit and Research in Tayside Scotland (GoDARTS)

  Hébert, H. L., Shepherd, B., Milburn, K., Veluchamy, A., Meng, W., Carr, F., Donnelly, L. A., Tavendale, R., Leese, G., Colhoun, H. M., Dow, E., Morris, A. D., Doney, A. S., Lang, C. C., Pearson, E. R., Smith, B. H. & Palmer, C. N. A., 1 Apr 2018, In: International Journal of Epidemiology. 47, 2, p. 380-381j 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  19 Citations (Scopus)

  238 Downloads (Pure)

• Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval

  Lin, H., van Setten, J., Smith, A. V., Bihlmeyer, N. A., Warren, H. R., Brody, J. A., Radmanesh, F., Hall, L., Grarup, N., Müller-Nurasyid, M., Boutin, T., Verweij, N., Lin, H. J., Li-Gao, R., van den Berg, M. E., Marten, J., Weiss, S., Prins, B. P., Haessler, J., Lyytikäinen, L-P. & 30 others, Mei, H., Harris, T. B., Launer, L. J., Li, M., Alonso, A., Soliman, E. Z., Connell, J. M., Huang, P. L., Weng, L-C., Jameson, H. S., Hucker, W., Hanley, A., Tucker, N. R., Chen, Y-D. I., Bis, J. C., Rice, K. M., Sitlani, C. M., Kors, J. A., Xie, Z., Wen, C., Magnani, J. W., Nelson, C. P., Kanters, J. K., Sinner, M. F., Strauch, K., Peters, A., Waldenberger, M., Meitinger, T., Bork-Jensen, J. & Smith, B. H., May 2018, In: Circulation: Genomic and Precision Medicine. 11, 5, p. 1-30 30 p., e002037.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Genetic Loci
  • Genetic Variation
  • Heart
  • Sinoatrial Node
  • Genome-Wide Association Study
  5 Citations (Scopus)

  408 Downloads (Pure)

• Common genetic variants associated with cognitive performance identified using the proxy-phenotype method

  Rietveld, C. A., Esko, T., Davies, G., Pers, T. H., Turley, P., Benyamin, B., Chabris, C. F., Emilsson, V., Johnson, A. D., Lee, J. J., Leeuw, C. D., Marioni, R. E., Medland, S. E., Miller, M. B., Rostapshova, O., van der Lee, S. J., Vinkhuyzen, A. A. E., Amin, N., Conley, D., Derringer, J. & 39 others, van Duijn, C. M., Fehrmann, R., Franke, L., Glaeser, E. L., Hansell, N. K., Hayward, C., Iacono, W. G., Ibrahim-Verbaas, C., Jaddoe, V., Karjalainen, J., Laibson, D., Lichtenstein, P., Liewald, D. C., Magnusson, P. K. E., Martin, N. G., McGue, M., McMahon, G., Pedersen, N. L., Pinker, S., Porteous, D. J., Posthuma, D., Rivadeneira, F., Smith, B. H., Starr, J. M., Tiemeier, H., Timpson, N. J., Trzaskowski, M., Uitterlinden, A. G., Verhulst, F. C., Ward, M. E., Wright, M. J., Davey Smith, G., Deary, I. J., Johannesson, M., Plomin, R., Visscher, P. M., Benjamin, D. J., Cesarini, D. & Koellinger, P. D., 23 Sep 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 38, p. 13790-13794 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Proxy
  • Single Nucleotide Polymorphism
  • Phenotype
  • Education
  • Memory
  134 Citations (Scopus)

• Copy number variation in the human Y chromosome in the UK population

  Wei, W., Fitzgerald, T., Ayub, Q., Massaia, A., Smith, B. B., Dominiczak, A. A., Morris, A. A., Porteous, D. D., Hurles, M. E., Tyler-Smith, C. & Xue, Y., Jul 2015, In: Human Genetics. 134, 7, p. 789-800 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Chromosomes, Human, Y
  • Genes
  • Population
  • Pseudogenes
  • Comparative Genomic Hybridization
  17 Citations (Scopus)

• Correction for Rietveld et al., Common genetic variants associated with cognitive performance identified using the proxy-phenotype method

  Rietveld, C. A., Esko, T., Davies, G., Pers, T. H., Turley, P., Benyamin, B., Chabris, C. F., Emilsson, V., Johnson, A. D., Lee, J. J., De Leeuw, C., Marioni, R. E., Medland, S. E., Miller, M. B., Rostapshova, O., Van Der Lee, S. J., Vinkhuyzen, A. A. E., Amin, N., Conley, D., Derringer, J. & 39 others, Van Duijn, C. M., Fehrmann, R., Franke, L., Glaeser, E. L., Hansell, N. K., Hayward, C., Iacono, W. G., Ibrahim-Verbaas, C., Jaddoe, V., Karjalainen, J., Laibson, D., Lichtenstein, P., Liewald, D. C., Magnusson, P. K. E., Martin, N. G., McGue, M., McMahon, G., Pedersen, N. L., Pinker, S., Porteous, D. J., Posthuma, D., Rivadeneira, F., Smith, B. H., Starr, J. M., Tiemeier, H., Timpson, N. J., Trzaskowski, M., Uitterlinden, A. G., Verhulst, F. C., Ward, M. E., Wright, M. J., Smith, G. D., Deary, I. J., Johannesson, M., Plomin, R., Visscher, P. M., Benjamin, D. J., Cesarini, D. & Koellinger, P. D., 27 Jan 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 4, 1 p., E380.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)

• Corrigendum to "Neuropathic pain in the general population:a systematic review of epidemiological studies": [PAIN® 155(4) pp. 654-662 (2014)] (DOI:10.1016/j.pain.2013.11.013)

  van Hecke, O., Austin, S. K., Khan, R. A., Smith, B. H. & Torrance, N., Sep 2014, In: Pain. 155, 9, p. 1907 1 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Decision Support for Diabetes in Scotland: Implementation and Evaluation of a Clinical Decision Support System

  Conway, N., Adamson, K. A., Cunningham, S. G., Emslie Smith, A., Nyberg, P., Smith, B. H., Wales, A. & Wake, D. J., 1 Mar 2018, In: Journal of Diabetes Science and Technology. 12, 2, p. 381-388 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Clinical Decision Support Systems
  • Scotland
  • Medical problems
  • Decision support systems
  • Health care
  3 Citations (Scopus)

  275 Downloads (Pure)

• Directional dominance on stature and cognition in diverse human populations

  Joshi, P. K., Esko, T., Mattsson, H., Eklund, N., Gandin, I., Nutile, T., Jackson, A. U., Schurmann, C., Smith, A. V., Zhang, W., Okada, Y., Stančáková, A., Faul, J. D., Zhao, W., Bartz, T. M., Concas, M. P., Franceschini, N., Enroth, S., Vitart, V., Trompet, S. & 32 others, Guo, X., Chasman, D. I., O'Connel, J. R., Corre, T., Nongmaithem, S. S., Chen, Y., Mangino, M., Ruggiero, D., Traglia, M., Farmaki, A-E., Kacprowski, T., Bjonnes, A., van der Spek, A., Wu, Y., Giri, A. K., Yanek, L. R., Wang, L., Hofer, E., Rietveld, C. A., McLeod, O., Cornelis, M. C., Pattaro, C., Verweij, N., Baumbach, C., Abdellaoui, A., Meng, W., Connell, J., Smith, B. H., BioBank Japan Project, Morris, A. D., Palmer, C. N. A. & Wilson, J. F., 23 Jul 2015, In: Nature. 523, 7561, p. 459-462 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Cognition
  • Genome
  • Inbreeding
  • Late Onset Disorders
  • Multifactorial Inheritance
  85 Citations (Scopus)

• Does a history of depression actually mediate smoking-related pain? findings from a cross-sectional general population-based study

  van Hecke, O., Torrance, N., Cochrane, L., Cavanagh, J., Donnan, P. T., Padmanabhan, S., Porteous, D. J., Hocking, L. & Smith, B. H., Oct 2014, In: European Journal of Pain. 18, 9, p. 1223-1230 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Smoking
  • Depression
  • Pain
  • Population
  • Smokers
  5 Citations (Scopus)

• DOLORisk: Study protocol for a multi-centre observational study to understand the risk factors and determinants of neuropathic pain [version 2; referees: 2 approved]

  Pascal, M. M. V., Themistocleous, A. C., Baron, R., Binder, A., Bouhassira, D., Crombez, G., Finnerup, N. B., Gierthmühlen, J., Granovsky, Y., Groop, L., Hebert, H. L., Jensen, T. S., Johnsen, K., McCarthy, M. I., Meng, W., Palmer, C. N. A., Rice, A. S. C., Serra, J., Solà, R., Yarnitsky, D. & 3 others, Smith, B. H., Attal, N. & Bennett, D. L. H., 29 May 2018, In: Wellcome Open Research. 3, p. 1-23 23 p., 63.

  Research output: Contribution to journal › Article › peer-review

  File

  • Neuralgia
  • Observational Studies
  • Network protocols
  • Ethics Committees
  • Neural Conduction
  7 Citations (Scopus)

  71 Downloads (Pure)

• DOLORisk: study protocol for a multi-centre observational study to understand the risk factors and determinants of neuropathic pain

  Pascal, M. M. V., Themistocleous, A. C., Baron, R., Binder, A., Bouhassira, D., Crombez, G., Finnerup, N. B., Gierthmühlen, J., Granovsky, Y., Groop, L., Hebert, H. L., Jensen, T. S., Johnsen, K., McCarthy, M. I., Meng, W., Palmer, C. N. A., Rice, A. S. C., Serra, J., Solà, R., Yarnitsky, D. & 3 others, Smith, B. H., Attal, N. & Bennett, D. L. H., 29 May 2018, In: Wellcome Open Research. 3, p. 1-16 16 p., 63.

  Research output: Contribution to journal › Article › peer-review

  File

  • Neuralgia
  • Observational Studies
  • Network protocols
  • Chemotherapy
  • Open access
  141 Downloads (Pure)

• Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function

  Artigas, M. S., Wain, L. V., Repapi, E., Obeidat, M., Sayers, I., Burton, P. R., Johnson, T., Zhao, J. H., Albrecht, E., Dominiczak, A. F., Kerr, S. M., Smith, B. H., Cadby, G., Hui, J., Palmer, L. J., Hingorani, A. D., Wannamethee, S. G., Whincup, P. H., Ebrahim, S., Smith, G. D. & 31 others, Barroso, I., Loos, R. J. F., Wareham, N. J., Cooper, C., Dennison, E., Shaheen, S. O., Liu, J. Z., Marchini, J., Dahgam, S., Naluai, A. T., Olin, A-C., Karrasch, S., Heinrich, J., Schulz, H., McKeever, T. M., Pavord, I. D., Heliovaara, M., Ripatti, S., Surakka, I., Blakey, J. D., Kahonen, M., Britton, J. R., Nyberg, F., Holloway, J. W., Lawlor, D. A., Morris, R. W., James, A. L., Jackson, C. M., Hall, I. P., Tobin, M. D. & SpiroMeta Consortium, Med Res Council Natl Survey Hlth D, 1 Oct 2011, In: American Journal of Respiratory and Critical Care Medicine. 184, 7, p. 786-795 10 p.

  Research output: Contribution to journal › Article › peer-review
  104 Citations (Scopus)

• Effect of smoking on blood pressure and resting heart rate: a Mendelian randomisation meta-analysis in the CARTA Consortium

  Linneberg, A., Jacobsen, R. K., Skaaby, T., Taylor, A. E., Fluharty, M. E., Jeppesen, J. L., Bjørngaard, J. H., Åsvold, B. O., Gabrielsen, M. E., Campbell, A., Marioni, R. E., Kumari, M., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Ahluwalia, T. S., Wannamethee, S. G., Lahti, J., Räikkönen, K. & 40 others, Palotie, A., Wong, A., Dalgård, C., Ford, I., Ben-Shlomo, Y., Christiansen, L., Kyvik, K. O., Kuh, D., Eriksson, J. G., Whincup, P. H., Mbarek, H., de Geus, E. J. C., Vink, J. M., Boomsma, D. I., Davey Smith, G., Lawlor, D. A., Kisialiou, A., McConnachie, A., Padmanabhan, S., Jukema, J. W., Power, C., Hyppönen, E., Preisig, M., Waeber, G., Vollenweider, P., Korhonen, T., Laatikainen, T., Salomaa, V., Kaprio, J., Kivimäki, M., Smith, B. H., Hayward, C., Sørensen, T. I. A., Thuesen, B. H., Sattar, N., Morris, R. W., Romundstad, P. R., Munafò, M. R., Jarvelin, M-R. & Husemoen, L. L. N., 2015, In: Circulation: Cardiovascular Genetics. 8, 6, p. 832-841 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mendelian Randomization Analysis
  • Meta-Analysis
  • Heart Rate
  • Smoking
  • Blood Pressure
  50 Citations (Scopus)

• Effects of education to facilitate knowledge about chronic pain for adults: a systematic review with meta-analysis

  Geneen, L. J., Martin, D. J., Adams, N., Clarke, C., Dunbar, M., Jones, D., McNamee, P., Schofield, P. & Smith, B. H., 1 Oct 2015, In: Systematic Reviews. 4, 21 p., 132.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Chronic Pain
  • Meta-Analysis
  • Systematic Reviews
  • Education
  • Pain
  44 Citations (Scopus)

  201 Downloads (Pure)

• Epidemiology and heritability of Major Depressive Disorder, stratified by age of onset, sex, and illness course in Generation Scotland: Scottish Family Health Study (GS:SFHS)

  Fernandez-Pujals, A. M., Adams, M. J., Thomson, P., McKechanie, A. G., Blackwood, D. H. R., Smith, B. H., Dominiczak, A. F., Morris, A. D., Matthews, K., Campbell, A., Linksted, P., Haley, C. S., Deary, I. J., Porteous, D. J., MacIntyre, D. J. & McIntosh, A. M., 16 Nov 2015, In: PLoS ONE. 10, 11, 18 p., e0142197.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • mental depression
  • Epidemiology
  • Family Health
  • Scotland
  • Major Depressive Disorder
  47 Citations (Scopus)

  302 Downloads (Pure)

• Erratum to: Copy number variation in the human Y chromosome in the UK population

  Wei, W., Fitzgerald, T. W., Ayub, Q., Massaia, A., Smith, B. H., Dominiczak, A. F., Morris, A. D., Porteous, D. J., Hurles, M. E., Tyler-Smith, C. & Xue, Y., Jul 2015, In: Human Genetics. 134, 7, p. 801 1 p.

  Research output: Contribution to journal › Article › peer-review

• Estimating the burden of disease in chronic pain with and without neuropathic characteristics: does the choice between the EQ-5D and SF-6D matter?

  Torrance, N., Lawson, K. D., Afolabi, E., Bennett, M. I., Serpell, M. G., Dunn, K. M. & Smith, B. H., Oct 2014, In: Pain. 155, 10, p. 1996-2004 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Chronic Pain
  • Health
  • Pain
  • Quality of Life
  • Mental Health
  37 Citations (Scopus)

  269 Downloads (Pure)

• Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6

  Prins, B. P., Mead, T. J., Brody, J. A., Sveinbjornsson, G., Ntalla, I., Bihlmeyer, N. A., van den Berg, M., Bork-Jensen, J., Cappellani, S., Van Duijvenboden, S., Klena, N. T., Gabriel, G. C., Liu, X., Gulec, C., Grarup, N., Haessler, J., Hall, L. M., Iorio, A., Isaacs, A., Li-Gao, R. & 93 others, Lin, H., Liu, C-T., Lyytikäinen, L-P., Marten, J., Mei, H., Müller-Nurasyid, M., Orini, M., Padmanabhan, S., Radmanesh, F., Ramirez, J., Robino, A., Schwartz, M., van Setten, J., Smith, A. V., Verweij, N., Warren, H. R., Weiss, S., Alonso, A., Arnar, D. O., Bots, M. L., de Boer, R. A., Dominiczak, A. F., Eijgelsheim, M., Ellinor, P. T., Guo, X., Felix, S. B., Harris, T. B., Hayward, C., Heckbert, S. R., Huang, P. L., Jukema, J. W., Kähönen, M., Kors, J. A., Lambiase, P. D., Launer, L. J., Li, M., Linneberg, A., Nelson, C. P., Pedersen, O., Perez, M., Peters, A., Polasek, O., Psaty, B. M., Raitakari, O. T., Rice, K., Rotter, J. I., Sinner, M. F., Soliman, E. Z., Spector, T. D., Strauch, K., Thorsteinsdottir, U., Tinker, A., Trompet, S., Uitterlinden, A. G., Vaartjes, I., van der Meer, P., Völker, U., Völzke, H., Waldenberger, M., Wilson, J. G., Xie, Z., Asselbergs, F. W., Dörr, M., van Duijn, C. M., Gasparini, P., Gudbjartsson, D. F., Gudnason, V., Hansen, T., Kääb, S., Kanters, J. K., Kooperberg, C., Lehtimäki, T., Lin, H. J., Lubitz, S. A., Mook-Kanamori, D. O., Conti, F. J., Newton-Cheh, C., Rosand, J., Rudan, I., Samani, N. J., Sinagra, G., Smith, B., Holm, H., Stricker, B. H. C., Ulivi, S., Sotoodehnia, N., Apte, S. S., van der Harst, P., Stefansson, K., Munroe, P. B., Arking, D. E., Lo, C. W. & Jamshidi, Y., 17 Jul 2018, In: Genome Biology. 19, p. 1-17 17 p., 87.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Exome
  • Connexin 43
  • meta-analysis
  • Gap Junctions
  • Sudden Cardiac Death
  15 Citations (Scopus)

  158 Downloads (Pure)

• Fine mapping the CETP region reveals a common intronic insertion associated to HDL-C

  van Leeuwen, E. M., Huffman, J. E., Bis, J. C., Isaacs, A., Mulder, M., Sabo, A., Smith, A. V., Demissie, S., Manichaikul, A., Brody, J. A., Feitosa, M. F., Duan, Q., Schraut, K. E., Navarro, P., van Vliet-Ostaptchouk, J. V., Zhu, G., Mbarek, H., Trompet, S., Verweij, N., Lyytikäinen, L-P. & 31 others, Deelen, J., Nolte, I. M., van der Laan, S. W., Davies, G., Vermeij-Verdoold, A. J., van Oosterhout, A. A., Vergeer-Drop, J. M., Arking, D. E., Trochet, H., Medina-Gomez, C., Rivadeneira, F., Uitterlinden, A. G., Dehghan, A., Franco, O. H., Sijbrands, E. J. G., Hofman, A., White, C. C., Mychaleckyj, J. C., Peloso, G. M., Swertz, M. A., Willemsen, G., de Geus, E. J. C., Milaneschi, Y., Penninx, B. W., Ford, I., Buckley, B. M., de Craen, A. J., Starr, J. M., Deary, I. J., Smith, B. H. & Generation Scotland, 2015, In: NPJ Aging and Mechanisms of Disease. 1, p. 1-9 9 p., 15011.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Cholesterol Ester Transfer Proteins
  • Meta-Analysis
  • Genome
  • Particle Size
  • Longevity
  3 Citations (Scopus)

  136 Downloads (Pure)

• Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

  23andMe Research Team, Lee, J. J., Wedow, R., Okbay, A., Kong, E., Maghzian, O., Zacher, M., Nguyen-Viet, T. A., Bowers, P., Sidorenko, J., Karlsson Linnér, R., Fontana, M. A., Kundu, T., Lee, C., Li, H., Li, R., Royer, R., Timshel, P. N., Walters, R. K., Willoughby, E. A. & 58 others, Yengo, L., Alver, M., Bao, Y., Clark, D. W., Day, F. R., Furlotte, N. A., Joshi, P. K., Kemper, K. E., Kleinman, A., Langenberg, C., Mägi, R., Trampush, J. W., Verma, S. S., Wu, Y., Lam, M., Zhao, J. H., Zheng, Z., Boardman, J. D., Campbell, H., Freese, J., Harris, K. M., Hayward, C., Herd, P., Kumari, M., Lencz, T., Luan, J., Malhotra, A. K., Metspalu, A., Milani, L., Ong, K. K., Smith, B. H., Perry, J. R. B., Porteous, D. J., Ritchie, M. D., Smart, M. C., Tung, J. Y., Wareham, N. J., Wilson, J. F., Beauchamp, J. P., Conley, D., Esko, T., Lehrer, S. F., Magnusson, P. K. E., Oskarsson, S., Pers, T. H., Robinson, M. R., Thom, K., Watson, C., Chabris, C. F., Meyer, M. N., Laibson, D., Yang, J., Johannesson, M., Koellinger, P. D., Turley, P., Visscher, P. M., Benjamin, D. J. & Cesarini, D., 23 Jul 2018, In: Nature Genetics. 50, 8, p. 1112-1121 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Genetic Association Studies
  • Genome-Wide Association Study
  • Single Nucleotide Polymorphism
  • Genome
  • Neurons
  383 Citations (Scopus)

  564 Downloads (Pure)

• Genetic and environmental determinants of stressful life events and their overlap with depression and neuroticism

  Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Clarke, T-K., Zeng, Y., Navrady, L., Xia, C., Haley, C. S., Campbell, A., Navarro, P., Amador, C., Adams, M. J., Howard, D. M., Soler, A., Hayward, C., Thomson, P. A., Smith, B., Padmanabhan, S., Hocking, L. J., Hall, L. S., Porteous, D. J., Deary, I. J. & 1 others, McIntosh, A. M., 14 Feb 2018, In: Wellcome Open Research. 3, p. 1-10 10 p., 11.

  Research output: Contribution to journal › Article › peer-review

  File

  • Neuroticism
  • Major Depressive Disorder
  • Depression
  • Genes
  • Population Biological Variation
  11 Citations (Scopus)

  177 Downloads (Pure)

• Genome-wide association analysis identifies six new loci associated with forced vital capacity

  Loth, D. W., Artigas, M. S., Gharib, S. A., Wain, L. V., Franceschini, N., Koch, B., Pottinger, T. D., Smith, A. V., Duan, Q., Oldmeadow, C., Lee, M. K., Strachan, D. P., James, A. L., Huffman, J. E., Vitart, V., Ramasamy, A., Wareham, N. J., Kaprio, J., Wang, X-Q., Trochet, H. & 33 others, Kähönen, M., Flexeder, C., Albrecht, E., Lopez, L. M., de Jong, K., Thyagarajan, B., Alves, A. C., Enroth, S., Omenaas, E., Joshi, P. K., Fall, T., Viñuela, A., Launer, L. J., Loehr, L. R., Fornage, M., Li, G., Wilk, J. B., Tang, W., Manichaikul, A., Lahousse, L., Harris, T. B., North, K. E., Rudnicka, A. R., Hui, J., Gu, X., Lumley, T., Wright, A. F., Hastie, N. D., Campbell, S., Generation Scotland, Smith, B. H., Tobin, M. D. & London, S. J., Jul 2014, In: Nature Genetics. 46, 7, p. 669-677 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Vital Capacity
  • Genome-Wide Association Study
  • Lung
  • Lung Diseases
  • Hispanic Americans
  88 Citations (Scopus)

• Genome-wide interaction study of a proxy for stress-sensitivity and its prediction of major depressive disorder

  Arnau-Soler, A., Adams, M. J., Generation Scotland, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Hayward, C. & Thomson, P. A., 20 Dec 2018, In: PLoS ONE. 13, 12, e0209160.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • mental depression
  • Neuroticism
  • Proxy
  • Major Depressive Disorder
  • Genes
  2 Citations (Scopus)

  166 Downloads (Pure)

• Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain

  Suri, P., Palmer, M. R., Tsepilov, Y. A., Freidin, M. B., Boer, C. G., Yau, M. S., Evans, D. S., Gelemanovic, A., Bartz, T. M., Nethander, M., Arbeeva, L., Karssen, L., Neogi, T., Campbell, A., Mellstrom, D., Ohlsson, C., Marshall, L. M., Orwoll, E., Uitterlinden, A., Rotter, J. I. & 17 others, Lauc, G., Psaty, B. M., Karlsson, M. K., Lane, N. E., Jarvik, G. P., Polasek, O., Hochberg, M., Jordan, J. M., Van Meurs, J. B. J., Jackson, R., Nielson, C. M., Mitchell, B. D., Smith, B. H., Hayward, C., Smith, N. L., Aulchenko, Y. S. & Williams, F. M. K., 27 Sep 2018, In: PLoS Genetics. 14, 9, p. 1-23 23 p., e1007601.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • back (body region)
  • meta-analysis
  • ancestry
  • pain
  • Back Pain
  20 Citations (Scopus)

  148 Downloads (Pure)

• Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium

  Morris, R. W., Taylor, A. E., Fluharty, M. E., Bjørngaard, J. H., Åsvold, B. O., Elvestad Gabrielsen, M., Campbell, A., Marioni, R., Kumari, M., Korhonen, T., Männistö, S., Marques-Vidal, P., Kaakinen, M., Cavadino, A., Postmus, I., Husemoen, L. L. N., Skaaby, T., Ahluwalia, T. V. S., Treur, J. L., Willemsen, G. & 42 others, Dale, C., Wannamethee, S. G., Lahti, J., Palotie, A., Räikkönen, K., McConnachie, A., Padmanabhan, S., Wong, A., Dalgård, C., Paternoster, L., Ben-Shlomo, Y., Tyrrell, J., Horwood, J., Fergusson, D. M., Kennedy, M. A., Nohr, E. A., Christiansen, L., Kyvik, K. O., Kuh, D., Watt, G., Eriksson, J. G., Whincup, P. H., Vink, J. M., Boomsma, D. I., Davey Smith, G., Lawlor, D., Linneberg, A., Ford, I., Jukema, J. W., Power, C., Hyppönen, E., Jarvelin, M-R., Preisig, M., Borodulin, K., Kaprio, J., Kivimaki, M., Smith, B. H., Hayward, C., Romundstad, P. R., Sørensen, T. I. A., Munafò, M. R. & Sattar, N., 11 Aug 2015, In: BMJ Open. 5, 8, 12 p., e008808.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Mendelian Randomization Analysis
  • Waist Circumference
  • Tobacco
  • Smokers
  • Meta-Analysis
  28 Citations (Scopus)

  122 Downloads (Pure)

• "I try and smile, I try and be cheery, I try not to be pushy. I try to say 'I'm here for help' but I leave feeling… worried": a qualitative study of perceptions of interactions with health professionals by community-based older adults with chronic pain

  Clarke, A., Martin, D., Jones, D., Schofield, P., Anthony, G., McNamee, P., Gray, D. & Smith, B. H., Sep 2014, In: PLoS ONE. 9, 9, 7 p., e105450.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • health care workers
  • pain
  • Chronic Pain
  • Emotions
  • Health
  15 Citations (Scopus)

  208 Downloads (Pure)

• Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility

  Wessel, J., Chu, A. Y., Willems, S. M., Wang, S., Yaghootkar, H., Brody, J. A., Dauriz, M., Hivert, M-F., Raghavan, S., Lipovich, L., Hidalgo, B., Fox, K., Huffman, J. E., An, P., Lu, Y., Rasmussen-Torvik, L. J., Grarup, N., Ehm, M. G., Li, L., Baldridge, A. S. & 31 others, Stančáková, A., Abrol, R., Besse, C., Boland, A., Bork-Jensen, J., Fornage, M., Freitag, D. F., Garcia, M. E., Guo, X., Hara, K., Isaacs, A., Jakobsdottir, J., Lange, L. A., Layton, J. C., Li, M., Hua Zhao, J., Meidtner, K., Morrison, A. C., Nalls, M. A., Peters, M. J., Sabater-Lleal, M., Schurmann, C., Silveira, A., Smith, A. V., Southam, L., Stoiber, M. H., Strawbridge, R. J., Taylor, K. D., Varga, T. V., Smith, B. H. & EPIC-InterAct Consortium, 29 Jan 2015, In: Nature Communications. 6, 16 p., 5897.

  Research output: Contribution to journal › Article › peer-review

  • fasting
  • Exome
  • glucose
  • Medical problems
  • insulin
  114 Citations (Scopus)

• Major depressive disorder and current psychological distress moderate the effect of polygenic risk for obesity on body mass index

  Clarke, T. K., Hall, L. S., Fernandez-Pujals, A. M., MacIntyre, D. J., Thomson, P., Hayward, C., Smith, B. H., Padmanabhan, S., Hocking, L. J., Deary, I. J., Porteous, D. J. & McIntosh, A. M., 30 Jun 2015, In: Translational Psychiatry. 5, 6, p. 1-6 6 p., e592.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Major Depressive Disorder
  • Body Mass Index
  • Obesity
  • Psychology
  • Neuroticism
  16 Citations (Scopus)

  176 Downloads (Pure)

• Management of chronic pain in primary care

  Smith, B. H. & Torrance, N., Jun 2011, In: Current Opinion in Supportive and Palliative Care. 5, 2, p. 137-142 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Chronic Pain
  • Primary Health Care
  • Self-Management
  • Pain Management
  • Pharmacology
  34 Citations (Scopus)

• Managing chronic pain in the non-specialist setting: a new SIGN guideline

  Smith, B. H., Hardman, J. D., Stein, A., Colvin, L. & SIGN Chronic Pain Guideline Development Group, 1 Jul 2014, In: British Journal of General Practice. 64, 624, p. e462-e464 3 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Meta-analysis of exome array data identifies six novel genetic loci for lung function

  Understanding Society Scientific Group, Jackson, V. E., Latourelle, J. C., Wain, L. V., Smith, A. V., Grove, M. L., Bartz, T. M., Obeidat, M., Province, M. A., Gao, W., Qaiser, B., Porteous, D. J., Cassano, P. A., Ahluwalia, T. S., Grarup, N., Li, J., Altmaier, E., Marten, J., Harris, S. E., Manichaikul, A. & 33 others, Pottinger, T. D., Li-Gao, R., Lind-Thomsen, A., Mahajan, A., Lahousse, L., Imboden, M., Teumer, A., Prins, B., Lyytikäinen, L-P., Eiriksdottir, G., Franceschini, N., Sitlani, C. M., Brody, J. A., Bossé, Y., Timens, W., Kraja, A., Loukola, A., Tang, W., Liu, Y., Bork-Jensen, J., Justesen, J. M., Linneberg, A., Lange, L. A., Rawal, R., Karrasch, S., Huffman, J. E., Smith, B. H., Davies, G., Burkart, K. M., Mychaleckyj, J. C., Morris, A. P., Tobin, M. D. & London, S. J., 7 Aug 2018, In: Wellcome Open Research. 3, 28 p., 4.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Exome
  • Genetic Loci
  • Pulmonary diseases
  • Single Nucleotide Polymorphism
  • Meta-Analysis
  7 Citations (Scopus)

  167 Downloads (Pure)

• Molecular genetic contributions to socioeconomic status and intelligence

  Marioni, R. E., Davies, G., Hayward, C., Liewald, D., Kerr, S. M., Campbell, A., Luciano, M., Smith, B. H., Padmanabhan, S., Hocking, L. J., Hastie, N. D., Wright, A. F., Porteous, D. J., Visscher, P. M. & Deary, I. J., 2014, In: Intelligence. 44, May-June, p. 26-32 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Molecular Genetics
  • Socioeconomic Status
  • Intelligence
  • Social Class
  • Molecular Biology
  80 Citations (Scopus)

  161 Downloads (Pure)