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  • Brian Lipworth
Article

Comparison of the effect of beclometasone/formoterol in asthma patients after methacholine-induced bronchoconstriction: a non-inferiority study using metered dose versus dry powder inhaler

Singh, D., van den Berg, F., Leaker, B., Corradi, M., Jabbal, S., Collarini, S., Mongelli, V., Santoro, L., Piccinno, A., Biondaro, S. & Lipworth, B., Apr 2019, In : British Journal of Clinical Pharmacology. 85, 4, p. 729-736 21 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
54 Downloads (Pure)

Correction to: Beneft:Risk Profle of Budesonide in Obstructive Airways Disease

Tashkin, D. P., Lipworth, B. & Brattsand, R., Nov 2019, In : Drugs. 79, 17, p. 1911 1 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Current appraisal of single inhaler triple therapy in COPD

Lipworth, B., Kuo, R. W. & Jabbal, S., 28 Sep 2018, In : International Journal of Chronic Obstructive Pulmonary Disease. 13, 13, p. 3003-3009 7 p.

Research output: Contribution to journalArticle

Open Access
File
14 Citations (Scopus)
161 Downloads (Pure)

Disconnection of pulmonary and systemic arterial stiffness in COPD

Weir-McCall, J. R., Liu-Shiu-Cheong, P. S., Struthers, A. D., Lipworth, B. J. & Houston, J. G., 28 May 2018, In : International Journal of Chronic Obstructive Pulmonary Disease. 13, p. 1755-1765 11 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
141 Downloads (Pure)

Effect of beta blockers in treatment of chronic obstructive pulmonary disease: a retrospective cohort study

Short, P. M., Lipworth, S. I. W., Elder, D. H. J., Schembri, S. & Lipworth, B. J., 10 May 2011, In : BMJ. 342, p. - 9 p., d2549.

Research output: Contribution to journalArticle

204 Citations (Scopus)

Effects of adding Tiotropium or Aclidinium as triple therapy using impulse oscillometry in COPD

Manoharan, A., Morrison, A. E. & Lipworth, B., Apr 2016, In : Lung. 194, 2, p. 259-266 8 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
181 Downloads (Pure)
Open Access
File
2 Citations (Scopus)
183 Downloads (Pure)

Effects of formoterol or salmeterol on impulse oscillometry in persistent asthma

Manoharan, A., von Wilamowitz-Moellendorff, A., Morrison, A. & Lipworth, B. J., Mar 2016, In : Journal of Allergy and Clinical Immunology. 137, 3, p. 727-733.e1 8 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
107 Downloads (Pure)

Effects of intravenous and oral β-blockade in persistent asthmatics controlled on inhaled corticosteroids

Short, P. M., Anderson, W. J., Williamson, P. A. & Lipworth, B. J., Feb 2014, In : Heart (British Cardiac Society). 100, 3, p. 219-223 5 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Effects of the inverse alpha-agonist doxazosin in allergic rhinitis

Manoharan, A., Morrison, A. E. & Lipworth, B. J., May 2016, In : Clinical and Experimental Allergy. 46, 5, p. 696-704 9 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
170 Downloads (Pure)

Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19

Herold, T., Jurinovic, V., Arnreich, C., Lipworth, B. J., Hellmuth, J. C., von Bergwelt-Baildon, M., Klein, M. & Weinberger, T., Jul 2020, In : Journal of Allergy and Clinical Immunology. 146, 1, p. 128-136.e4 13 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)

Erratum to: Comparative lung bioavailability of fluticasone/salmeterol via a breath-actuated spacer and conventional plastic spacers

Nair, A., McKinlay, L., Williamson, P., Short, P., Burns, P. & Lipworth, B. J., Jun 2017, In : European Journal of Clinical Pharmacology. 73, 6, p. 793-793 1 p.

Research output: Contribution to journalArticle

Glycopyrrolate/formoterol fumarate metered dose inhaler for maintenance-naïve patients with chronic obstructive pulmonary disease: a post-hoc analysis of the randomized PINNACLE trials

Zheng, J., Xu, J-F., Jenkins, M., Assam, P. N., Wang, L. & Lipworth, B. J., 12 Mar 2020, In : Respiratory Research. 21, 1, p. 1-10 10 p., 69.

Research output: Contribution to journalArticle

Open Access
File
32 Downloads (Pure)

Glycopyrrolate/formoterol fumarate metered dose inhaler improves lung function versus monotherapies in GOLD category a patients with COPD: Pooled data from the phase III PINNACLE studies

Martinez, F. J., Rabe, K. F., Lipworth, B. J., Arora, S., Jenkins, M., Martin, U. J. & Reisner, C., 2020, In : International Journal of COPD. 15, p. 99-106 8 p.

Research output: Contribution to journalArticle

Open Access
File
41 Downloads (Pure)

Impact of long-acting bronchodilators and exposure to inhaled corticosteroids on mortality in COPD: a real-life retrospective cohort study

Manoharan, A., Short, P. M., Anderson, W. J. & Lipworth, B. J., Oct 2014, In : Lung. 192, 5, p. 649-652 4 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Implication of alternative minimal clinically important difference threshold estimation on technology assessment

Brixner, D., Meltzer, E. O., Marland, K., Carroll, C. A., Munzel, U. & Lipworth, B., 6 Dec 2016, In : International Journal of Technology Assessment in Health Care. 32, 6, p. 371-375 5 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
135 Downloads (Pure)

Improved lung function and patient-reported outcomes with co-suspension delivery technology glycopyrrolate/formoterol fumarate metered dose inhaler in COPD: a randomized Phase III study conducted in Asia, Europe, and the USA

Lipworth, B. J., Collier, D. J., Gon, Y., Zhong, N., Nishi, K., Chen, R., Arora, S., Maes, A., Siddiqui, S., Reisner, C. & Martin, U. J., 26 Sep 2018, In : International Journal of Chronic Obstructive Pulmonary Disease. 13, p. 2969-2984 16 p.

Research output: Contribution to journalArticle

Open Access
File
17 Citations (Scopus)
133 Downloads (Pure)

Inhaled corticosteroid dose-response in asthma: Should we measure inflammation?

Anderson, W. J., Short, P., Jabbal, S. & Lipworth, B., Feb 2017, In : Annals of Allergy, Asthma & Immunology. 118, 2, p. 179-185 6 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
153 Downloads (Pure)

I say IOS you say AOS: comparative bias in respiratory impedance measurements

Kuo, C., Jabbal, S. & Lipworth, B., Aug 2019, In : Lung. 197, 4, p. 473-481 9 p.

Research output: Contribution to journalArticle

Open Access
File
3 Citations (Scopus)
111 Downloads (Pure)

Is Gly16Arg β2 Receptor Polymorphism Related to Impulse Oscillometry in a Real-Life Asthma Clinic Setting?

Jabbal, S., Manoharan, A., Lipworth, J., Anderson, W., Short, P. & Lipworth, B., Apr 2016, In : Lung. 194, 2, p. 267-271 5 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
132 Downloads (Pure)

Making simple things complicated using anti-inflammatory reliever therapy

Lipworth, B., Kuo, C. R. & Chan, R., 30 Apr 2020, In : European Respiratory Journal. 55, 4, 2000267.

Research output: Contribution to journalArticle

Nasal AMP and histamine challenge within and outside the pollen season in patients with seasonal allergic rhinitis

Vaidyanathan, S., Williamson, P., Clearie, K., Morrison, A. & Lipworth, B., Jan 2011, In : Journal of Allergy and Clinical Immunology. 127, 1, p. 173-203.e3 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Pharmacokinetic and pharmacodynamic comparison of hydrofluoroalkane and chlorofluorocarbon formulations of budesonide

Clearie, K. L., Williamson, P. A., Meldrum, K., Gillen, M., Carlsson, L-G., Carlholm, M., Ekelund, J. & Lipworth, B. J., Apr 2011, In : British Journal of Clinical Pharmacology. 71, 4, p. 504-513 10 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Pragmatic evaluation of inhaled corticosteroid particle size formulations on asthma control

Kuo, C., Jabbal, S., Anderson, W. & Lipworth, B., 9 Oct 2019, In : Clinical and Experimental Allergy. 49, 10, p. 1321-1327 7 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
14 Downloads (Pure)

Prescribing of β-adrenoceptor antagonists in asthma: an observational study

Morales, D. R., Guthrie, B., Lipworth, B. J., Donnan, P. T. & Jackson, C., Jun 2011, In : Thorax. 66, 6, p. 502-507 6 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

Proof of concept evaluation of trough airway hyper-responsiveness following regular racemic or levosalbutamol in genotype-stratified steroid-treated persistent asthmatic patients

Anderson, W. J., Short, P. M., Williamson, P. A., Morrison, A. E., Palmer, C., Tavendale, R. & Lipworth, B. J., 1 Jan 2014, In : Clinical Science. 126, 1, p. 75-83 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Proof of concept study to evaluate step-down therapy with inhaled corticosteroid alone or additive therapy on surrogate inflammatory markers in asthma

McKinlay, L., Williamson, P. A., Short, P. M., Fardon, T. & Lipworth, B. J., Jan 2011, In : British Journal of Clinical Pharmacology. 71, 1, p. 128-131 4 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Pulmonary and systemic arterial stiffness are disconnected in COPD

Weir-McCall, J., Liu Shiu Cheong, P., Struthers, A., Lipworth, B. & Houston, J., 28 May 2018, In : International Journal of Chronic Obstructive Pulmonary Disease. 13, p. 1755-1765 16 p.

Research output: Contribution to journalArticle

Pulmonary arterial stiffening in COPD and its implications for right ventricular remodelling.

Weir-McCall, J. R., Liu Shiu Cheong, P. S. K., Struthers, A. D., Lipworth, B. J. & Houston, J. G., Aug 2018, In : European Radiology. 28, 8, p. 3464-3472 9 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
221 Downloads (Pure)
Open Access
File
46 Downloads (Pure)

Relationships between airway hyperresponsiveness, inflammation, and calibre in asthma

Short, P. M., Lipworth, S. I. W. & Lipworth, B. J., Dec 2011, In : Lung. 189, 6, p. 493-497 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
Open Access
File
22 Citations (Scopus)
174 Downloads (Pure)
Open Access
File
27 Citations (Scopus)
299 Downloads (Pure)
42 Citations (Scopus)

Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5)

Bousquet, J., Farrell, J., Crooks, G., Hellings, P., Bel, E. H., Bewick, M., Chavannes, N. H., de Sousa, J. C., Cruz, A. A., Haahtela, T., Joos, G., Khaltaev, N., Malva, J., Muraro, A., Nogues, M., Palkonen, S., Pedersen, S., Robalo-Cordeiro, C., Samolinski, B., Strandberg, T. & 301 others, Valiulis, A., Yorgancioglu, A., Zuberbier, T., Bedbrook, A., Aberer, W., Adachi, M., Agusti, A., Akdis, C. A., Akdis, M., Ankri, J., Alonso, A., Annesi-Maesano, I., Ansotegui, I. J., Anto, J. M., Arnavielhe, S., Arshad, H., Bai, C., Baiardini, I., Bachert, C., Baigenzhin, A. K., Barbara, C., Bateman, E. D., Beghé, B., Kheder, A. B., Bennoor, K. S., Benson, M., Bergmann, K. C., Bieber, T., Bindslev-Jensen, C., Bjermer, L., Blain, H., Blasi, F., Boner, A. L., Bonini, M., Bonini, S., Bosnic-Anticevitch, S., Boulet, L. P., Bourret, R., Bousquet, P. J., Braido, F., Briggs, A. H., Brightling, C. E., Brozek, J., Buhl, R., Burney, P. G., Bush, A., Caballero-Fonseca, F., Caimmi, D., Calderon, M. A., Calverley, P. M., Camargos, P. A. M., Canonica, G. W., Camuzat, T., Carlsen, K. H., Carr, W., Carriazo, A., Casale, T., Cepeda Sarabia, A. M., Chatzi, L., Chen, Y. Z., Chiron, R., Chkhartishvili, E., Chuchalin, A. G., Chung, K. F., Ciprandi, G., Cirule, I., Cox, L., Costa, D. J., Custovic, A., Dahl, R., Dahlen, S. E., Darsow, U., De Carlo, G., De Blay, F., Dedeu, T., Deleanu, D., De Manuel Keenoy, E., Demoly, P., Denburg, J. A., Devillier, P., Didier, A., Dinh-Xuan, A. T., Djukanovic, R., Dokic, D., Douagui, H., Dray, G., Dubakiene, R., Durham, S. R., Dykewicz, M. S., El-Gamal, Y., Emuzyte, R., Fabbri, L. M., Fletcher, M., Fiocchi, A., Fink Wagner, A., Fonseca, J., Fokkens, W. J., Forastiere, F., Frith, P., Gaga, M., Gamkrelidze, A., Garces, J., Garcia-Aymerich, J., Gemicioğlu, B., Gereda, J. E., González Diaz, S., Gotua, M., Grisle, I., Grouse, L., Gutter, Z., Guzmán, M. A., Heaney, L. G., Hellquist-Dahl, B., Henderson, D., Hendry, A., Heinrich, J., Heve, D., Horak, F., Hourihane, J. O. B., Howarth, P., Humbert, M., Hyland, M. E., Illario, M., Ivancevich, J. C., Jardim, J. R., Jares, E. J., Jeandel, C., Jenkins, C., Johnston, S. L., Jonquet, O., Julge, K., Jung, K. S., Just, J., Kaidashev, I., Khaitov, M. R., Kalayci, O., Kalyoncu, A. F., Keil, T., Keith, P. K., Klimek, L., Koffi N'Goran, B., Kolek, V., Koppelman, G. H., Kowalski, M. L., Kull, I., Kuna, P., Kvedariene, V., Lambrecht, B., Lau, S., Larenas-Linnemann, D., Laune, D., Le, L. T. T., Lieberman, P., Lipworth, B., Li, J., Lodrup Carlsen, K., Louis, R., MacNee, W., Magard, Y., Magnan, A., Mahboub, B., Mair, A., Majer, I., Makela, M. J., Manning, P., Mara, S., Marshall, G. D., Masjedi, M. R., Matignon, P., Maurer, M., Mavale-Manuel, S., Melén, E., Melo-Gomes, E., Meltzer, E. O., Menzies-Gow, A., Merk, H., Michel, J. P., Miculinic, N., Mihaltan, F., Milenkovic, B., Mohammad, G. M. Y., Molimard, M., Momas, I., Montilla-Santana, A., Morais-Almeida, M., Morgan, M., Mösges, R., Mullol, J., Nafti, S., Namazova-Baranova, L., Naclerio, R., Neou, A., Neffen, H., Nekam, K., Niggemann, B., Ninot, G., Nyembue, T. D., O'Hehir, R. E., Ohta, K., Okamoto, Y., Okubo, K., Ouedraogo, S., Paggiaro, P., Pali-Schöll, I., Panzner, P., Papadopoulos, N., Papi, A., Park, H. S., Passalacqua, G., Pavord, I., Pawankar, R., Pengelly, R., Pfaar, O., Picard, R., Pigearias, B., Pin, I., Plavec, D., Poethig, D., Pohl, W., Popov, T. A., Portejoie, F., Potter, P., Postma, D., Price, D., Rabe, K. F., Raciborski, F., Radier Pontal, F., Repka-Ramirez, S., Reitamo, S., Rennard, S., Rodenas, F., Roberts, J., Roca, J., Rodriguez Mañas, L., Rolland, C., Roman Rodriguez, M., Romano, A., Rosado-Pinto, J., Rosario, N., Rosenwasser, L., Rottem, M., Ryan, D., Sanchez-Borges, M., Scadding, G. K., Schunemann, H. J., Serrano, E., Schmid-Grendelmeier, P., Schulz, H., Sheikh, A., Shields, M., Siafakas, N., Sibille, Y., Similowski, T., Simons, F. E. R., Sisul, J. C., Skrindo, I., Smit, H. A., Solé, D., Sooronbaev, T., Spranger, O., Stelmach, R., Sterk, P. J., Sunyer, J., Thijs, C., To, T., Todo-Bom, A., Triggiani, M., Valenta, R., Valero, A. L., Valia, E., Valovirta, E., Van Ganse, E., van Hage, M., Vandenplas, O., Vasankari, T., Vellas, B., Vestbo, J., Vezzani, G., Vichyanond, P., Viegi, G., Vogelmeier, C., Vontetsianos, T., Wagenmann, M., Wallaert, B., Walker, S., Wang, D. Y., Wahn, U., Wickman, M., Williams, D. M., Williams, S., Wright, J., Yawn, B. P., Yiallouros, P. K., Yusuf, O. M., Zaidi, A., Zar, H. J., Zernotti, M. E., Zhang, L., Zhong, N., Zidarn, M. & Mercier, J., 29 Jul 2016, In : Clinical and Translational Allergy. 6, p. 1-18 18 p., 29.

Research output: Contribution to journalArticle

Open Access
File
32 Citations (Scopus)
114 Downloads (Pure)
Open Access
File
3 Citations (Scopus)
148 Downloads (Pure)

Small airway dysfunction is associated with poorer asthma control

Manoharan, A., Anderson, W. J., Lipworth, J., Ibrahim, I. & Lipworth, B. J., Nov 2014, In : European Respiratory Journal. 44, 5, p. 1353-1355 3 p.

Research output: Contribution to journalArticle

Open Access
File
30 Citations (Scopus)
130 Downloads (Pure)

Supervised step-down of inhaled corticosteroids in the community: an observational study

Clearie, K. L., Jackson, C. M., Fardon, T. C., Williamson, P. A., Vaidyanathan, S., Burns, P. & Lipworth, B. J., Apr 2011, In : Respiratory Medicine. 105, 4, p. 558-565 8 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Tadalafil in patients with chronic obstructive pulmonary disease: a randomised, double-blind, parallel-group, placebo-controlled trial

Goudie, A. R., Lipworth, B. J., Hopkinson, P. J., Wei, L. & Struthers, A. D., Apr 2014, In : The Lancet Respiratory Medicine. 2, 4, p. 293-300 8 p.

Research output: Contribution to journalArticle

Open Access
File
56 Citations (Scopus)
158 Downloads (Pure)

The burden of chronic obstructive pulmonary disease associated with maintenance monotherapy in the UK

Edwards, S. C., Fairbrother, S. E., Scowcroft, A., Chiu, G., Ternouth, A. & Lipworth, B. J., 22 Nov 2016, In : International Journal of Chronic Obstructive Pulmonary Disease. 11, 1, p. 2851-2858 8 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
132 Downloads (Pure)

The inverse agonist propranolol confers no corticosteroid-sparing activity in mild-to-moderate persistent asthma

Anderson, W. J., Short, P. M., Williamson, P. A., Manoharan, A. & Lipworth, B. J., Dec 2014, In : Clinical Science. 127, 11, p. 635-643 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

The potential role of direct and indirect bronchial challenge testing to identify overtreatment of community managed asthma

Manoharan, A., Lipworth, B., Craig, E. & Jackson, C., Oct 2014, In : Clinical and Experimental Allergy. 44, 10, p. 1240-1245 6 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Tolerability of Bisoprolol on Domiciliary Spirometry in COPD

Jabbal, S. & Lipworth, B. J., 14 Oct 2017, In : Lung. 196, 1, p. 11-14 4 p.

Research output: Contribution to journalArticle

Open Access
File
185 Downloads (Pure)

Toll-like receptor 3 blockade in rhinovirus-induced experimental asthma exacerbations: A Randomized Controlled Study

Silkoff, P. E., Flavin, S., Gordon, R., Loza, M. J., Sterk, P. J., Lutter, R., Diamant, Z., Turner, R. B., Lipworth, B. J., Proud, D., Singh, D., Eich, A., Backer, V., Gern, J. E., Herzmann, C., Halperin, S. A., Mensinga, T. T., Del Vecchio, A. M., Branigan, P., San Mateo, L. & 3 others, Baribaud, F., Barnathan, E. S. & Johnston, S. L., Apr 2018, In : Journal of Allergy and Clinical Immunology. 141, 4, p. 1220-1230 11 p.

Research output: Contribution to journalArticle

Open Access
File
18 Citations (Scopus)
186 Downloads (Pure)

Treatment of chronic rhinosinusitis with nasal polyposis with oral steroids followed by topical steroids: a randomized trial

Vaidyanathan, S., Barnes, M., Williamson, P., Hopkinson, P., Donnan, P. T. & Lipworth, B., 2011, In : Annals of Internal Medicine. 154, 5, p. 293-302 12 p.

Research output: Contribution to journalArticle

103 Citations (Scopus)

Underuse of β-blockers in heart failure and chronic obstructive pulmonary disease

Lipworth, B., Skinner, D., Devereux, G., Thomas, V., Ling Zhi Jie, J., Martin, J., Carter, V. & Price, D. B., 1 Dec 2016, In : Heart. 102, 23, p. 1909-1914 7 p.

Research output: Contribution to journalArticle

Open Access
File
38 Citations (Scopus)
254 Downloads (Pure)