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• Article

  ACP Journal Club. Review: Tiotropium mist inhaler increases mortality in chronic obstructive pulmonary disease

  Lipworth, B. J., 2011, In: Annals of Internal Medicine. 155, 8, p. JC4-6

  Research output: Contribution to journal › Article › peer-review

• Adverse respiratory effect of acute beta-blocker exposure in asthma: a systematic review and meta-analysis of randomized controlled trials

  Morales, D. R., Jackson, C., Lipworth, B. J., Donnan, P. T. & Guthrie, B., Apr 2014, In: Chest. 145, 4, p. 779-786

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Meta-Analysis
  • Systematic Reviews
  • Randomized Controlled Trials
  • Celiprolol
  58 Citations (Scopus)

• Airway dysfunction in nasal polyposis: a spectrum of asthmatic disease?

  Williamson, P. A., Vaidyanathan, S., Clearie, K., Barnes, M. & Lipworth, B. J., Oct 2011, In: Clinical and Experimental Allergy. 41, 10, p. 1379-1385 7 p.

  Research output: Contribution to journal › Article › peer-review
  28 Citations (Scopus)

• Allopurinol in Patients with Pulmonary Hypertension Associated with Chronic Lung Disease

  Liu Shiu Cheong, P. S. K., Lipworth, B. J., Weir-McCall, J. R., Houston, J. G. & Struthers, A. D., 25 Aug 2020, In: International Journal of Chronic Obstructive Pulmonary Disease. 2020, 15, p. 2015-2024 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Allopurinol
  • Pulmonary Hypertension
  • Lung Diseases
  • Chronic Disease
  • Placebos
  14 Downloads (Pure)

• An algorithm recommendation for the pharmacological management of allergic rhinitis in the UK: a consensus statement from an expert panel

  Lipworth, B., Newton, J., Ram, B., Small, I. & Schwarze, J., 23 Jan 2017, In: NPJ Primary Care Respiratory Medicine. 27, p. 1-8 8 p., 3.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Allergic Rhinitis
  • Consensus
  • Pharmacology
  • Primary Health Care
  • Secondary Care
  7 Citations (Scopus)

  169 Downloads (Pure)

• Anti-inflammatory reliever therapy for asthma

  Lipworth, B., Chan, R. & RuiWen Kuo, C., Jan 2020, In: Annals of Allergy, Asthma & Immunology. 124, 1, p. 13-15 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  1 Citation (Scopus)

  27 Downloads (Pure)

• Assessment of small-airways disease using alveolar nitric oxide and impulse oscillometry in asthma and COPD

  Williamson, P. A., Clearie, K., Menzies, D., Vaidyanathan, S. & Lipworth, B. J., Apr 2011, In: Lung. 189, 2, p. 121-129 9 p.

  Research output: Contribution to journal › Article › peer-review
  67 Citations (Scopus)

• Asthma Step-Down Strategies: Perhaps the Patient Should Decide?

  Lipworth, B. & Israel, E., Mar 2018, In: The Journal of Allergy and Clinical Immunology: In Practice. 6, 2, p. 644-645 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  149 Downloads (Pure)

• Benefits of glycopyrrolate/formoterol fumarate metered dose inhaler (GFF MDI) in improving lung function and reducing exacerbations in patients with moderate-to-very severe COPD: a pooled analysis of the PINNACLE studies

  Martinez, F. J., Lipworth, B. J., Rabe, K. F., Collier, D. J., Ferguson, G. T., Sethi, S., Feldman, G. J., O'Brien, G., Jenkins, M. & Reisner, C., 25 May 2020, In: Respiratory Research. 21, 1, p. 1-14 14 p., 128.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Glycopyrrolate
  • Formoterol Fumarate
  • Metered Dose Inhalers
  • Chronic Obstructive Pulmonary Disease
  • Lung
  1 Citation (Scopus)

  25 Downloads (Pure)

• Bronchoprotective tolerance with indacaterol is not modified by concomitant tiotropium in persistent asthma

  Jabbal, S., Manoharan, A. & Lipworth, B. J., Oct 2017, In: Clinical and Experimental Allergy. 47, 10, p. 1239-1245 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • indacaterol
  • Tiotropium Bromide
  • Asthma
  • Mannitol
  • Muscarinic Antagonists
  5 Citations (Scopus)

  195 Downloads (Pure)

• Cardiopulmonary interactions with beta-blockers and inhaled therapy in COPD

  Jabbal, S., Anderson, W., Short, P., Morrison, A., Manoharan, A. & Lipworth, B. J., Dec 2017, In: QJM : an International Journal of Medicine. 110, 12, p. 785-792 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Carvedilol
  • Bisoprolol
  • Chronic Obstructive Pulmonary Disease
  • Forced Expiratory Volume
  • Tiotropium Bromide
  3 Citations (Scopus)

  174 Downloads (Pure)

• Comparative lung bioavailability of fluticasone/salmeterol via a breath-actuated spacer and conventional plastic spacers

  Nair, A., McKinlay, L., Williamson, P., Short, P., Burns, P. & Lipworth, B. J., Apr 2011, In: European Journal of Clinical Pharmacology. 67, 4, p. 355-363 9 p.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• Comparison of bronchodilator response in patients with asthma and healthy subjects using spirometry and oscillometry

  Nair, A., Ward, J. & Lipworth, B. J., Oct 2011, In: Annals of Allergy, Asthma & Immunology. 107, 4, p. 317-322 6 p.

  Research output: Contribution to journal › Article › peer-review
  33 Citations (Scopus)

• Current appraisal of single inhaler triple therapy in COPD

  Lipworth, B., Kuo, R. W. & Jabbal, S., 28 Sep 2018, In: International Journal of Chronic Obstructive Pulmonary Disease. 13, 13, p. 3003-3009 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Muscarinic Antagonists
  • Nebulizers and Vaporizers
  • Chronic Obstructive Pulmonary Disease
  • Adrenal Cortex Hormones
  • fluticasone furoate
  16 Citations (Scopus)

  171 Downloads (Pure)

• Disconnection of pulmonary and systemic arterial stiffness in COPD

  Weir-McCall, J. R., Liu-Shiu-Cheong, P. S., Struthers, A. D., Lipworth, B. J. & Houston, J. G., 28 May 2018, In: International Journal of Chronic Obstructive Pulmonary Disease. 13, p. 1755-1765 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Vascular Stiffness
  • Chronic Obstructive Pulmonary Disease
  • Pulse Wave Analysis
  • Lung
  • Healthy Volunteers
  1 Citation (Scopus)

  157 Downloads (Pure)

• Don’t Forget about Facilitatory Effects of Corticosteroids on b ₂-Adrenoceptors in Acute Asthma

  Lipworth, B., Chan, R. & Kuo, C. R., 15 Dec 2020, In: American Journal of Respiratory and Critical Care Medicine. 202, 12, p. 1743 1 p.

  Research output: Contribution to journal › Article › peer-review

• Effect of beta blockers in treatment of chronic obstructive pulmonary disease: a retrospective cohort study

  Short, P. M., Lipworth, S. I. W., Elder, D. H. J., Schembri, S. & Lipworth, B. J., 10 May 2011, In: BMJ. 342, p. - 9 p., d2549.

  Research output: Contribution to journal › Article › peer-review
  208 Citations (Scopus)

• Effects of contrast administration on cardiac MRI volumetric, flow and pulse wave velocity quantification using manual and software-based analysis

  Fathi, A., Weir-McCall, J. R., Struthers, A. D., Lipworth, B. J. & Houston, J. G., 2018, In: British Journal of Radiology. 91, 1084, 14 p., 20170717.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Pulse Wave Analysis
  • Gadolinium
  • Software
  • Contrast Media
  • gadoterate meglumine
  2 Citations (Scopus)

  191 Downloads (Pure)

• Effects of intravenous and oral β-blockade in persistent asthmatics controlled on inhaled corticosteroids

  Short, P. M., Anderson, W. J., Williamson, P. A. & Lipworth, B. J., Feb 2014, In: Heart (British Cardiac Society). 100, 3, p. 219-223 5 p.

  Research output: Contribution to journal › Article › peer-review

  • esmolol
  • Propranolol
  • Adrenal Cortex Hormones
  • Asthma
  • Cardiovascular Diseases
  15 Citations (Scopus)

• Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19

  Herold, T., Jurinovic, V., Arnreich, C., Lipworth, B. J., Hellmuth, J. C., von Bergwelt-Baildon, M., Klein, M. & Weinberger, T., Jul 2020, In: Journal of Allergy and Clinical Immunology. 146, 1, p. 128-136.e4 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Coronavirus
  • Artificial Respiration
  • Interleukin-6
  • Respiratory Insufficiency
  • Biomarkers
  110 Citations (Scopus)

• Erratum to: Comparative lung bioavailability of fluticasone/salmeterol via a breath-actuated spacer and conventional plastic spacers

  Nair, A., McKinlay, L., Williamson, P., Short, P., Burns, P. & Lipworth, B. J., Jun 2017, In: European Journal of Clinical Pharmacology. 73, 6, p. 793-793 1 p.

  Research output: Contribution to journal › Article › peer-review

• Glycopyrrolate/formoterol fumarate metered dose inhaler for maintenance-naïve patients with chronic obstructive pulmonary disease: a post-hoc analysis of the randomized PINNACLE trials

  Zheng, J., Xu, J-F., Jenkins, M., Assam, P. N., Wang, L. & Lipworth, B. J., 12 Mar 2020, In: Respiratory Research. 21, 10 p., 69.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Glycopyrrolate
  • Formoterol Fumarate
  • Metered Dose Inhalers
  • Chronic Obstructive Pulmonary Disease
  • Maintenance
  1 Citation (Scopus)

  36 Downloads (Pure)

• Glycopyrrolate/formoterol fumarate metered dose inhaler improves lung function versus monotherapies in GOLD category a patients with COPD: Pooled data from the phase III PINNACLE studies

  Martinez, F. J., Rabe, K. F., Lipworth, B. J., Arora, S., Jenkins, M., Martin, U. J. & Reisner, C., 2020, In: International Journal of COPD. 15, p. 99-106 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Glycopyrrolate
  • Formoterol Fumarate
  • Metered Dose Inhalers
  • Chronic Obstructive Pulmonary Disease
  • Lung
  1 Citation (Scopus)

  46 Downloads (Pure)

• Impact of long-acting bronchodilators and exposure to inhaled corticosteroids on mortality in COPD: a real-life retrospective cohort study

  Manoharan, A., Short, P. M., Anderson, W. J. & Lipworth, B. J., Oct 2014, In: Lung. 192, 5, p. 649-652 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Bronchodilator Agents
  • Chronic Obstructive Pulmonary Disease
  • Muscarinic Antagonists
  • Adrenal Cortex Hormones
  • Cohort Studies
  12 Citations (Scopus)

• Improved lung function and patient-reported outcomes with co-suspension delivery technology glycopyrrolate/formoterol fumarate metered dose inhaler in COPD: a randomized Phase III study conducted in Asia, Europe, and the USA

  Lipworth, B. J., Collier, D. J., Gon, Y., Zhong, N., Nishi, K., Chen, R., Arora, S., Maes, A., Siddiqui, S., Reisner, C. & Martin, U. J., 26 Sep 2018, In: International Journal of Chronic Obstructive Pulmonary Disease. 13, p. 2969-2984 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Glycopyrrolate
  • Formoterol Fumarate
  • Metered Dose Inhalers
  • Patient Reported Outcome Measures
  • Chronic Obstructive Pulmonary Disease
  20 Citations (Scopus)

  143 Downloads (Pure)

• Impulse oscillometry bronchodilator response and asthma control

  Kuo, C. R., Chan, R. & Lipworth, B., 31 Jul 2020, In: The Journal of Allergy and Clinical Immunology: In Practice.

  Research output: Contribution to journal › Article › peer-review

• Inhaled corticosteroid dose-response in asthma: Should we measure inflammation?

  Anderson, W. J., Short, P., Jabbal, S. & Lipworth, B., Feb 2017, In: Annals of Allergy, Asthma & Immunology. 118, 2, p. 179-185 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Architectural Accessibility
  • Adrenal Cortex Hormones
  • Asthma
  • Confidence Intervals
  • Inflammation
  7 Citations (Scopus)

  170 Downloads (Pure)

• Lack of clinically relevant differences between combination therapy and monotherapy in COPD

  Lipworth, B. J., Apr 2014, In: European Respiratory Journal. 43, 4, p. 1204 1 p.

  Research output: Contribution to journal › Article › peer-review

• Making simple things complicated using anti-inflammatory reliever therapy

  Lipworth, B., Kuo, C. R. & Chan, R., 30 Apr 2020, In: European Respiratory Journal. 55, 4, 2000267.

  Research output: Contribution to journal › Article › peer-review

  • Formoterol Fumarate
  • Budesonide
  • Asthma
  • Anti-Inflammatory Agents
  • Reading

• Nasal AMP and histamine challenge within and outside the pollen season in patients with seasonal allergic rhinitis

  Vaidyanathan, S., Williamson, P., Clearie, K., Morrison, A. & Lipworth, B., Jan 2011, In: Journal of Allergy and Clinical Immunology. 127, 1, p. 173-203.e3 9 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Pharmacokinetic and pharmacodynamic comparison of hydrofluoroalkane and chlorofluorocarbon formulations of budesonide

  Clearie, K. L., Williamson, P. A., Meldrum, K., Gillen, M., Carlsson, L-G., Carlholm, M., Ekelund, J. & Lipworth, B. J., Apr 2011, In: British Journal of Clinical Pharmacology. 71, 4, p. 504-513 10 p.

  Research output: Contribution to journal › Article › peer-review
  24 Citations (Scopus)

• Pragmatic clinical perspective on biologics for severe refractory type 2 asthma

  Chan, R., Kuo, C. R. & Lipworth, B., 13 Jul 2020, In: The Journal of Allergy and Clinical Immunology: In Practice.

  Research output: Contribution to journal › Article › peer-review

  • Biological Products
  • Asthma
  • benralizumab
  • reslizumab
  • SAR231893

• Prescribing of β-adrenoceptor antagonists in asthma: an observational study

  Morales, D. R., Guthrie, B., Lipworth, B. J., Donnan, P. T. & Jackson, C., Jun 2011, In: Thorax. 66, 6, p. 502-507 6 p.

  Research output: Contribution to journal › Article › peer-review
  15 Citations (Scopus)

• Proof of concept evaluation of trough airway hyper-responsiveness following regular racemic or levosalbutamol in genotype-stratified steroid-treated persistent asthmatic patients

  Anderson, W. J., Short, P. M., Williamson, P. A., Morrison, A. E., Palmer, C., Tavendale, R. & Lipworth, B. J., 1 Jan 2014, In: Clinical Science. 126, 1, p. 75-83 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Respiratory Hypersensitivity
  • Proof of Concept Study
  • Albuterol
  • Steroids
  • Genotype
  3 Citations (Scopus)

• Proof of concept study to evaluate step-down therapy with inhaled corticosteroid alone or additive therapy on surrogate inflammatory markers in asthma

  McKinlay, L., Williamson, P. A., Short, P. M., Fardon, T. & Lipworth, B. J., Jan 2011, In: British Journal of Clinical Pharmacology. 71, 1, p. 128-131 4 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Pulmonary and systemic arterial stiffness are disconnected in COPD

  Weir-McCall, J., Liu Shiu Cheong, P., Struthers, A., Lipworth, B. & Houston, J., 28 May 2018, In: International Journal of Chronic Obstructive Pulmonary Disease. 13, p. 1755-1765 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Vascular Stiffness
  • Chronic Obstructive Pulmonary Disease
  • Lung
  • Healthy Volunteers
  • Biomarkers

• Pulmonary arterial stiffening in COPD and its implications for right ventricular remodelling.

  Weir-McCall, J. R., Liu Shiu Cheong, P. S. K., Struthers, A. D., Lipworth, B. J. & Houston, J. G., Aug 2018, In: European Radiology. 28, 8, p. 3464-3472 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Ventricular Remodeling
  • Chronic Obstructive Pulmonary Disease
  • Pulse Wave Analysis
  • Lung
  • Stroke Volume
  3 Citations (Scopus)

  231 Downloads (Pure)

• Randomized controlled trial of triple versus dual inhaler therapy on small airways in smoking asthmatics

  Jabbal, S., Kuo, C. R. & Lipworth, B., 1 Oct 2020, In: Clinical and Experimental Allergy. 50, 10, p. 1140-1147 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • olodaterol
  • Nebulizers and Vaporizers
  • Oscillometry
  • Smoking
  • Randomized Controlled Trials
  61 Downloads (Pure)

• Relationships between airway hyperresponsiveness, inflammation, and calibre in asthma

  Short, P. M., Lipworth, S. I. W. & Lipworth, B. J., Dec 2011, In: Lung. 189, 6, p. 493-497 5 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Respiratory effect of beta-blockers in people with asthma and cardiovascular disease: population-based nested case control study

  Morales, D. R., Lipworth, B. J., Donnan, P. T., Jackson, C. & Guthrie, B., 27 Jan 2017, In: BMC Medicine. 15, 9 p., 18.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Case-Control Studies
  • Asthma
  • Cardiovascular Diseases
  • Population
  • Incidence
  31 Citations (Scopus)

  318 Downloads (Pure)

• Safety risks for patients with aspirin-exacerbated respiratory disease after acute exposure to selective nonsteroidal anti-inflammatory drugs and COX-2 inhibitors: meta-analysis of controlled clinical trials

  Morales, D. R., Lipworth, B. J., Guthrie, B., Jackson, C., Donnan, P. T. & Santiago, V. H., Jul 2014, In: Journal of Allergy and Clinical Immunology. 134, 1, p. 40-45.e10 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Cyclooxygenase 2 Inhibitors
  • Controlled Clinical Trials
  • Acute Disease
  • Patient Safety
  • Aspirin
  43 Citations (Scopus)

• Sensitivity of lung resistance and compliance to beta-blocker induced bronchoconstriction and long acting beta-agonist withdrawal in COPD

  Jabbal, S. & Lipworth, B. J., Feb 2018, In: Lung. 196, 1, p. 15-18 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Carvedilol
  • Lung Compliance
  • Bronchoconstriction
  • Oscillometry
  • Chronic Obstructive Pulmonary Disease
  3 Citations (Scopus)

  156 Downloads (Pure)

• Small airway dysfunction is associated with poorer asthma control

  Manoharan, A., Anderson, W. J., Lipworth, J., Ibrahim, I. & Lipworth, B. J., Nov 2014, In: European Respiratory Journal. 44, 5, p. 1353-1355 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  30 Citations (Scopus)

  139 Downloads (Pure)

• Supervised step-down of inhaled corticosteroids in the community: an observational study

  Clearie, K. L., Jackson, C. M., Fardon, T. C., Williamson, P. A., Vaidyanathan, S., Burns, P. & Lipworth, B. J., Apr 2011, In: Respiratory Medicine. 105, 4, p. 558-565 8 p.

  Research output: Contribution to journal › Article › peer-review
  19 Citations (Scopus)

• Tadalafil in patients with chronic obstructive pulmonary disease: a randomised, double-blind, parallel-group, placebo-controlled trial

  Goudie, A. R., Lipworth, B. J., Hopkinson, P. J., Wei, L. & Struthers, A. D., Apr 2014, In: The Lancet Respiratory Medicine. 2, 4, p. 293-300 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Tadalafil
  • Chronic Obstructive Pulmonary Disease
  • Placebos
  • Dyspepsia
  • Quality of Life
  59 Citations (Scopus)

  173 Downloads (Pure)

• The inverse agonist propranolol confers no corticosteroid-sparing activity in mild-to-moderate persistent asthma

  Anderson, W. J., Short, P. M., Williamson, P. A., Manoharan, A. & Lipworth, B. J., Dec 2014, In: Clinical Science. 127, 11, p. 635-643 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Propranolol
  • Adrenal Cortex Hormones
  • Asthma
  • apaflurane
  • Beclomethasone
  13 Citations (Scopus)

• The potential role of direct and indirect bronchial challenge testing to identify overtreatment of community managed asthma

  Manoharan, A., Lipworth, B., Craig, E. & Jackson, C., Oct 2014, In: Clinical and Experimental Allergy. 44, 10, p. 1240-1245 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Medical Overuse
  • Asthma
  • Methacholine Chloride
  • Mannitol
  • Medical Informatics
  13 Citations (Scopus)

• Tolerability of Bisoprolol on Domiciliary Spirometry in COPD

  Jabbal, S. & Lipworth, B. J., 14 Oct 2017, In: Lung. 196, 1, p. 11-14 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Bisoprolol
  • Spirometry
  • Chronic Obstructive Pulmonary Disease
  • Adrenal Cortex Hormones
  • Muscarinic Antagonists
  194 Downloads (Pure)

• Toll-like receptor 3 blockade in rhinovirus-induced experimental asthma exacerbations: A Randomized Controlled Study

  Silkoff, P. E., Flavin, S., Gordon, R., Loza, M. J., Sterk, P. J., Lutter, R., Diamant, Z., Turner, R. B., Lipworth, B. J., Proud, D., Singh, D., Eich, A., Backer, V., Gern, J. E., Herzmann, C., Halperin, S. A., Mensinga, T. T., Del Vecchio, A. M., Branigan, P., San Mateo, L. & 3 others, Baribaud, F., Barnathan, E. S. & Johnston, S. L., Apr 2018, In: Journal of Allergy and Clinical Immunology. 141, 4, p. 1220-1230 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Toll-Like Receptor 3
  • Rhinovirus
  • Asthma
  • Placebos
  • Healthy Volunteers
  18 Citations (Scopus)

  218 Downloads (Pure)

• Treatment of chronic rhinosinusitis with nasal polyposis with oral steroids followed by topical steroids: a randomized trial

  Vaidyanathan, S., Barnes, M., Williamson, P., Hopkinson, P., Donnan, P. T. & Lipworth, B., 2011, In: Annals of Internal Medicine. 154, 5, p. 293-302 12 p.

  Research output: Contribution to journal › Article › peer-review
  106 Citations (Scopus)