Find Research outputs

Search results

• Article

  ACP Journal Club. Review: Tiotropium mist inhaler increases mortality in chronic obstructive pulmonary disease

  Lipworth, B. J., 2011, In: Annals of Internal Medicine. 155, 8, p. JC4-6

  Research output: Contribution to journal › Article › peer-review

• Adverse respiratory effect of acute beta-blocker exposure in asthma: a systematic review and meta-analysis of randomized controlled trials

  Morales, D. R., Jackson, C., Lipworth, B. J., Donnan, P. T. & Guthrie, B., Apr 2014, In: Chest. 145, 4, p. 779-786

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Meta-Analysis
  • Systematic Reviews
  • Randomized Controlled Trials
  • Celiprolol
  59 Citations (Scopus)

• Airway dysfunction in nasal polyposis: a spectrum of asthmatic disease?

  Williamson, P. A., Vaidyanathan, S., Clearie, K., Barnes, M. & Lipworth, B. J., Oct 2011, In: Clinical and Experimental Allergy. 41, 10, p. 1379-1385 7 p.

  Research output: Contribution to journal › Article › peer-review
  28 Citations (Scopus)

• Allopurinol in Patients with Pulmonary Hypertension Associated with Chronic Lung Disease

  Liu Shiu Cheong, P. S. K., Lipworth, B. J., Weir-McCall, J. R., Houston, J. G. & Struthers, A. D., 25 Aug 2020, In: International Journal of Chronic Obstructive Pulmonary Disease. 2020, 15, p. 2015-2024 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Allopurinol
  • Pulmonary Hypertension
  • Lung Diseases
  • Chronic Disease
  • Placebos
  19 Downloads (Pure)

• An algorithm recommendation for the pharmacological management of allergic rhinitis in the UK: a consensus statement from an expert panel

  Lipworth, B., Newton, J., Ram, B., Small, I. & Schwarze, J., 23 Jan 2017, In: NPJ Primary Care Respiratory Medicine. 27, p. 1-8 8 p., 3.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Allergic Rhinitis
  • Consensus
  • Pharmacology
  • Primary Health Care
  • Secondary Care
  7 Citations (Scopus)

  175 Downloads (Pure)

• Anti-inflammatory reliever therapy for asthma

  Lipworth, B., Chan, R. & RuiWen Kuo, C., Jan 2020, In: Annals of Allergy, Asthma & Immunology. 124, 1, p. 13-15 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  1 Citation (Scopus)

  32 Downloads (Pure)

• Assessment of small-airways disease using alveolar nitric oxide and impulse oscillometry in asthma and COPD

  Williamson, P. A., Clearie, K., Menzies, D., Vaidyanathan, S. & Lipworth, B. J., Apr 2011, In: Lung. 189, 2, p. 121-129 9 p.

  Research output: Contribution to journal › Article › peer-review
  68 Citations (Scopus)

• Benefits of glycopyrrolate/formoterol fumarate metered dose inhaler (GFF MDI) in improving lung function and reducing exacerbations in patients with moderate-to-very severe COPD: a pooled analysis of the PINNACLE studies

  Martinez, F. J., Lipworth, B. J., Rabe, K. F., Collier, D. J., Ferguson, G. T., Sethi, S., Feldman, G. J., O'Brien, G., Jenkins, M. & Reisner, C., 25 May 2020, In: Respiratory Research. 21, 1, p. 1-14 14 p., 128.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Glycopyrrolate
  • Formoterol Fumarate
  • Metered Dose Inhalers
  • Chronic Obstructive Pulmonary Disease
  • Lung
  1 Citation (Scopus)

  26 Downloads (Pure)

• Bronchoprotective tolerance with indacaterol is not modified by concomitant tiotropium in persistent asthma

  Jabbal, S., Manoharan, A. & Lipworth, B. J., Oct 2017, In: Clinical and Experimental Allergy. 47, 10, p. 1239-1245 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • indacaterol
  • Tiotropium Bromide
  • Asthma
  • Mannitol
  • Muscarinic Antagonists
  5 Citations (Scopus)

  199 Downloads (Pure)

• Cardiopulmonary interactions with beta-blockers and inhaled therapy in COPD

  Jabbal, S., Anderson, W., Short, P., Morrison, A., Manoharan, A. & Lipworth, B. J., Dec 2017, In: QJM : an International Journal of Medicine. 110, 12, p. 785-792 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Carvedilol
  • Bisoprolol
  • Chronic Obstructive Pulmonary Disease
  • Forced Expiratory Volume
  • Tiotropium Bromide
  3 Citations (Scopus)

  183 Downloads (Pure)

• Comparative lung bioavailability of fluticasone/salmeterol via a breath-actuated spacer and conventional plastic spacers

  Nair, A., McKinlay, L., Williamson, P., Short, P., Burns, P. & Lipworth, B. J., Apr 2011, In: European Journal of Clinical Pharmacology. 67, 4, p. 355-363 9 p.

  Research output: Contribution to journal › Article › peer-review
  11 Citations (Scopus)

• Comparison of bronchodilator response in patients with asthma and healthy subjects using spirometry and oscillometry

  Nair, A., Ward, J. & Lipworth, B. J., Oct 2011, In: Annals of Allergy, Asthma & Immunology. 107, 4, p. 317-322 6 p.

  Research output: Contribution to journal › Article › peer-review
  33 Citations (Scopus)

• Don’t Forget about Facilitatory Effects of Corticosteroids on b ₂-Adrenoceptors in Acute Asthma

  Lipworth, B., Chan, R. & Kuo, C. R., 15 Dec 2020, In: American Journal of Respiratory and Critical Care Medicine. 202, 12, p. 1743 1 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  6 Downloads (Pure)

• Effect of beta blockers in treatment of chronic obstructive pulmonary disease: a retrospective cohort study

  Short, P. M., Lipworth, S. I. W., Elder, D. H. J., Schembri, S. & Lipworth, B. J., 10 May 2011, In: BMJ. 342, p. - 9 p., d2549.

  Research output: Contribution to journal › Article › peer-review
  208 Citations (Scopus)

• Effects of intravenous and oral β-blockade in persistent asthmatics controlled on inhaled corticosteroids

  Short, P. M., Anderson, W. J., Williamson, P. A. & Lipworth, B. J., Feb 2014, In: Heart (British Cardiac Society). 100, 3, p. 219-223 5 p.

  Research output: Contribution to journal › Article › peer-review

  • esmolol
  • Propranolol
  • Adrenal Cortex Hormones
  • Asthma
  • Cardiovascular Diseases
  15 Citations (Scopus)

• Elevated levels of IL-6 and CRP predict the need for mechanical ventilation in COVID-19

  Herold, T., Jurinovic, V., Arnreich, C., Lipworth, B. J., Hellmuth, J. C., von Bergwelt-Baildon, M., Klein, M. & Weinberger, T., Jul 2020, In: Journal of Allergy and Clinical Immunology. 146, 1, p. 128-136.e4 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Coronavirus
  • Artificial Respiration
  • Interleukin-6
  • Respiratory Insufficiency
  • Biomarkers
  127 Citations (Scopus)

• Erratum to: Comparative lung bioavailability of fluticasone/salmeterol via a breath-actuated spacer and conventional plastic spacers

  Nair, A., McKinlay, L., Williamson, P., Short, P., Burns, P. & Lipworth, B. J., Jun 2017, In: European Journal of Clinical Pharmacology. 73, 6, p. 793-793 1 p.

  Research output: Contribution to journal › Article › peer-review

• Glycopyrrolate/formoterol fumarate metered dose inhaler for maintenance-naïve patients with chronic obstructive pulmonary disease: a post-hoc analysis of the randomized PINNACLE trials

  Zheng, J., Xu, J-F., Jenkins, M., Assam, P. N., Wang, L. & Lipworth, B. J., 12 Mar 2020, In: Respiratory Research. 21, 10 p., 69.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Glycopyrrolate
  • Formoterol Fumarate
  • Metered Dose Inhalers
  • Chronic Obstructive Pulmonary Disease
  • Maintenance
  1 Citation (Scopus)

  41 Downloads (Pure)

• Glycopyrrolate/formoterol fumarate metered dose inhaler improves lung function versus monotherapies in GOLD category a patients with COPD: Pooled data from the phase III PINNACLE studies

  Martinez, F. J., Rabe, K. F., Lipworth, B. J., Arora, S., Jenkins, M., Martin, U. J. & Reisner, C., 2020, In: International Journal of COPD. 15, p. 99-106 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Glycopyrrolate
  • Formoterol Fumarate
  • Metered Dose Inhalers
  • Chronic Obstructive Pulmonary Disease
  • Lung
  1 Citation (Scopus)

  52 Downloads (Pure)

• Impact of long-acting bronchodilators and exposure to inhaled corticosteroids on mortality in COPD: a real-life retrospective cohort study

  Manoharan, A., Short, P. M., Anderson, W. J. & Lipworth, B. J., Oct 2014, In: Lung. 192, 5, p. 649-652 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Bronchodilator Agents
  • Chronic Obstructive Pulmonary Disease
  • Muscarinic Antagonists
  • Adrenal Cortex Hormones
  • Cohort Studies
  12 Citations (Scopus)

• Impulse oscillometry bronchodilator response and asthma control

  Kuo, C. R., Chan, R. & Lipworth, B., 31 Jul 2020, In: The Journal of Allergy and Clinical Immunology: In Practice.

  Research output: Contribution to journal › Article › peer-review

• Inhaled corticosteroid dose-response in asthma: Should we measure inflammation?

  Anderson, W. J., Short, P., Jabbal, S. & Lipworth, B., Feb 2017, In: Annals of Allergy, Asthma & Immunology. 118, 2, p. 179-185 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Architectural Accessibility
  • Adrenal Cortex Hormones
  • Asthma
  • Confidence Intervals
  • Inflammation
  7 Citations (Scopus)

  177 Downloads (Pure)

• Lack of clinically relevant differences between combination therapy and monotherapy in COPD

  Lipworth, B. J., Apr 2014, In: European Respiratory Journal. 43, 4, p. 1204 1 p.

  Research output: Contribution to journal › Article › peer-review

• Making simple things complicated using anti-inflammatory reliever therapy

  Lipworth, B., Kuo, C. R. & Chan, R., 30 Apr 2020, In: European Respiratory Journal. 55, 4, 2000267.

  Research output: Contribution to journal › Article › peer-review

  • Formoterol Fumarate
  • Budesonide
  • Asthma
  • Anti-Inflammatory Agents
  • Reading

• Nasal AMP and histamine challenge within and outside the pollen season in patients with seasonal allergic rhinitis

  Vaidyanathan, S., Williamson, P., Clearie, K., Morrison, A. & Lipworth, B., Jan 2011, In: Journal of Allergy and Clinical Immunology. 127, 1, p. 173-203.e3 9 p.

  Research output: Contribution to journal › Article › peer-review
  6 Citations (Scopus)

• Pharmacokinetic and pharmacodynamic comparison of hydrofluoroalkane and chlorofluorocarbon formulations of budesonide

  Clearie, K. L., Williamson, P. A., Meldrum, K., Gillen, M., Carlsson, L-G., Carlholm, M., Ekelund, J. & Lipworth, B. J., Apr 2011, In: British Journal of Clinical Pharmacology. 71, 4, p. 504-513 10 p.

  Research output: Contribution to journal › Article › peer-review
  24 Citations (Scopus)

• Pragmatic clinical perspective on biologics for severe refractory type 2 asthma

  Chan, R., Kuo, C. R. & Lipworth, B., 13 Jul 2020, In: The Journal of Allergy and Clinical Immunology: In Practice.

  Research output: Contribution to journal › Article › peer-review

  • Biological Products
  • Asthma
  • benralizumab
  • reslizumab
  • SAR231893

• Prescribing of β-adrenoceptor antagonists in asthma: an observational study

  Morales, D. R., Guthrie, B., Lipworth, B. J., Donnan, P. T. & Jackson, C., Jun 2011, In: Thorax. 66, 6, p. 502-507 6 p.

  Research output: Contribution to journal › Article › peer-review
  15 Citations (Scopus)

• Proof of concept evaluation of trough airway hyper-responsiveness following regular racemic or levosalbutamol in genotype-stratified steroid-treated persistent asthmatic patients

  Anderson, W. J., Short, P. M., Williamson, P. A., Morrison, A. E., Palmer, C., Tavendale, R. & Lipworth, B. J., 1 Jan 2014, In: Clinical Science. 126, 1, p. 75-83 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Respiratory Hypersensitivity
  • Proof of Concept Study
  • Albuterol
  • Steroids
  • Genotype
  3 Citations (Scopus)

• Proof of concept study to evaluate step-down therapy with inhaled corticosteroid alone or additive therapy on surrogate inflammatory markers in asthma

  McKinlay, L., Williamson, P. A., Short, P. M., Fardon, T. & Lipworth, B. J., Jan 2011, In: British Journal of Clinical Pharmacology. 71, 1, p. 128-131 4 p.

  Research output: Contribution to journal › Article › peer-review
  5 Citations (Scopus)

• Randomized controlled trial of triple versus dual inhaler therapy on small airways in smoking asthmatics

  Jabbal, S., Kuo, C. R. & Lipworth, B., Oct 2020, In: Clinical and Experimental Allergy. 50, 10, p. 1140-1147 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • olodaterol
  • Nebulizers and Vaporizers
  • Oscillometry
  • Smoking
  • Randomized Controlled Trials
  1 Citation (Scopus)

  70 Downloads (Pure)

• Relationships between airway hyperresponsiveness, inflammation, and calibre in asthma

  Short, P. M., Lipworth, S. I. W. & Lipworth, B. J., Dec 2011, In: Lung. 189, 6, p. 493-497 5 p.

  Research output: Contribution to journal › Article › peer-review
  4 Citations (Scopus)

• Respiratory effect of beta-blockers in people with asthma and cardiovascular disease: population-based nested case control study

  Morales, D. R., Lipworth, B. J., Donnan, P. T., Jackson, C. & Guthrie, B., 27 Jan 2017, In: BMC Medicine. 15, 9 p., 18.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Case-Control Studies
  • Asthma
  • Cardiovascular Diseases
  • Population
  • Incidence
  34 Citations (Scopus)

  332 Downloads (Pure)

• Safety risks for patients with aspirin-exacerbated respiratory disease after acute exposure to selective nonsteroidal anti-inflammatory drugs and COX-2 inhibitors: meta-analysis of controlled clinical trials

  Morales, D. R., Lipworth, B. J., Guthrie, B., Jackson, C., Donnan, P. T. & Santiago, V. H., Jul 2014, In: Journal of Allergy and Clinical Immunology. 134, 1, p. 40-45.e10 16 p.

  Research output: Contribution to journal › Article › peer-review

  • Cyclooxygenase 2 Inhibitors
  • Controlled Clinical Trials
  • Acute Disease
  • Patient Safety
  • Aspirin
  44 Citations (Scopus)

• Small airway dysfunction is associated with poorer asthma control

  Manoharan, A., Anderson, W. J., Lipworth, J., Ibrahim, I. & Lipworth, B. J., Nov 2014, In: European Respiratory Journal. 44, 5, p. 1353-1355 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
  30 Citations (Scopus)

  146 Downloads (Pure)

• Supervised step-down of inhaled corticosteroids in the community: an observational study

  Clearie, K. L., Jackson, C. M., Fardon, T. C., Williamson, P. A., Vaidyanathan, S., Burns, P. & Lipworth, B. J., Apr 2011, In: Respiratory Medicine. 105, 4, p. 558-565 8 p.

  Research output: Contribution to journal › Article › peer-review
  19 Citations (Scopus)

• Tadalafil in patients with chronic obstructive pulmonary disease: a randomised, double-blind, parallel-group, placebo-controlled trial

  Goudie, A. R., Lipworth, B. J., Hopkinson, P. J., Wei, L. & Struthers, A. D., Apr 2014, In: The Lancet Respiratory Medicine. 2, 4, p. 293-300 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Tadalafil
  • Chronic Obstructive Pulmonary Disease
  • Placebos
  • Dyspepsia
  • Quality of Life
  60 Citations (Scopus)

  180 Downloads (Pure)

• The inverse agonist propranolol confers no corticosteroid-sparing activity in mild-to-moderate persistent asthma

  Anderson, W. J., Short, P. M., Williamson, P. A., Manoharan, A. & Lipworth, B. J., Dec 2014, In: Clinical Science. 127, 11, p. 635-643 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Propranolol
  • Adrenal Cortex Hormones
  • Asthma
  • apaflurane
  • Beclomethasone
  13 Citations (Scopus)

• The potential role of direct and indirect bronchial challenge testing to identify overtreatment of community managed asthma

  Manoharan, A., Lipworth, B., Craig, E. & Jackson, C., Oct 2014, In: Clinical and Experimental Allergy. 44, 10, p. 1240-1245 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Medical Overuse
  • Asthma
  • Methacholine Chloride
  • Mannitol
  • Medical Informatics
  13 Citations (Scopus)

• Tolerability of Bisoprolol on Domiciliary Spirometry in COPD

  Jabbal, S. & Lipworth, B. J., 14 Oct 2017, In: Lung. 196, 1, p. 11-14 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Bisoprolol
  • Spirometry
  • Chronic Obstructive Pulmonary Disease
  • Adrenal Cortex Hormones
  • Muscarinic Antagonists
  198 Downloads (Pure)

• Treatment of chronic rhinosinusitis with nasal polyposis with oral steroids followed by topical steroids: a randomized trial

  Vaidyanathan, S., Barnes, M., Williamson, P., Hopkinson, P., Donnan, P. T. & Lipworth, B., 2011, In: Annals of Internal Medicine. 154, 5, p. 293-302 12 p.

  Research output: Contribution to journal › Article › peer-review
  107 Citations (Scopus)

• Unlocking the quiet zone: the small airway asthma phenotype

  Lipworth, B., Manoharan, A. & Anderson, W., 2014, In: The Lancet Respiratory Medicine. 2, 6, p. 497-506 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Asthma
  • Phenotype
  • Nebulizers and Vaporizers
  • Lung
  • Adrenal Cortex Hormones
  67 Citations (Scopus)

• Use of inhaled corticosteroids in asthma and coronavirus disease 2019: Keep calm and carry on

  Lipworth, B., Chan, R. & Kuo, C., 1 Nov 2020, In: Annals of Allergy, Asthma & Immunology. 125, 5, p. 503-504 2 p.

  Research output: Contribution to journal › Article › peer-review

• β-Agonist safety and the elephant in the room?

  Williamson, P. A., Short, P. M., McKinlay, L., Palmer, C. N. A. & Lipworth, B. J., Jun 2011, In: Thorax. 66, 6, p. 542 1 p.

  Research output: Contribution to journal › Article › peer-review
  1 Citation (Scopus)
• Book/Film/Article review

  A cross sectional survey of inhaler technique and taining among Dundee medical students

  Williamson, P. A., McKinlay, L., Ho, B., Mohammed, A. Y. & Lipworth, B. J., Feb 2011, In: Journal of Allergy and Clinical Immunology. 127, 2 Supplement, p. AB117-AB117 1 p.

  Research output: Contribution to journal › Book/Film/Article review › peer-review

• Comparison of montelukast versus salmeterol in children with asthma carrying-at-risk beta(2)adrenergic receptor polymorphism: a genotype-stratified randomised controlled trial

  Basu, K., Donald, H. P., Lipworth, B. J., Tavendale, R., MacGregor, D. F., Ogston, S. A., Palmer, C. N. A. & Mukhopadhyay, S., 2011, In: Journal of Allergy and Clinical Immunology. 127, 2 Supplement, p. AB212 1 p.

  Research output: Contribution to journal › Book/Film/Article review › peer-review

• Correlation between sinus scoring and nasal nitric oxide in nasal polyp disease

  Vaidyanathan, S., McKinlay, L., Williamson, P. A. & Lipworth, B. J., Feb 2011, In: Journal of Allergy and Clinical Immunology. 127, 2 Supplement, p. AB122-AB122 1 p.

  Research output: Contribution to journal › Book/Film/Article review › peer-review

• Effects of extra-fine inhaled and oral corticosteroids on alveolar nitric oxide in COPD

  Short, P., Williamson, P. A. & Lipworth, B. J., Dec 2011, In: Thorax. 66, Supplement 4, p. A172-A172 1 p., P257.

  Research output: Contribution to journal › Book/Film/Article review › peer-review

• Inhaled and systemic corticosteroid response in moderate-to-severe asthma assessed by extended exhaled nitric oxide and lung function

  Williamson, P. A., Short, P. M. & Lipworth, B. J., Dec 2011, In: Thorax. 66, Supplement 4, p. A7-A8 2 p., S9.

  Research output: Contribution to journal › Book/Film/Article review › peer-review

• Sensitivity of impulse oscillometry and spirometry in the assessment of beta-blocker induced bronchoconstriction and beta-agonist bronchodilatation in mild-to-moderate asthmatics

  Short, P. M., Williamson, P. A. & Lipworth, B. J., Dec 2011, In: Thorax. 66, Supplement 4, p. A7-A7 1 p., S8.

  Research output: Contribution to journal › Book/Film/Article review › peer-review
  34 Citations (Scopus)